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Tear Jerker: Cardfight Vanguard
Misaki's backstory being revealed via flashbacks of her parents' deaths that give her a breakdown until she has to stop what triggers them. Which is playing Vanguard.
Episode 49, specifically Ren and Kai's backstory. Watching Ren transform from an Adorkable kid into his currentpersona is heartbreaking.
In episode 50, Aichi's anguished rant at Kai. Effects of PSY Qualia aside, he was probably keeping most of what he said bottled up inside for pretty much the entire series...
