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Tear Jerker: Batman and Sons
The entire Cabbage Patch story, but "Look, there's Momma" , especially since it hits very close to home in terms of what the DC Comics Catwoman has been going through as of late.
The One-Scene Wonder with Cassandra Cain who is watching the Batfamily (and even waves at baby Terry), but is called back by her father. The way she walks back to her father, back hunched over and face sad made the scene worse.