Role Association: Anime Japanese
- Ai Yori Aoshi: College student Ben Tennyson bumps into childhood friend/arranged bride Saber, become an Official Couple (in secret) and move into a mansion consisting of Ben's guardian Yukari Tanizaki and tenants/unwanted harems Kagome Higurashi, Laharl, Kusu Kusu and Komugi Nakahara.
- Ah! My Goddess: Tenchi Masaki is an ordinary college student who accidentally gets The Boss to be his girlfriend. The Boss's sisters Ivy and Storm are also major characters.
- AKIRA: Yuusuke Urameshi becomes insane after being tested on by the government. It's up to his friend Ironhide and Karen Joshua to stop him.
- Allison & Lillia: Teen Genius Kid Salsamille and Ace Pilot Hinata Hyuuga go on a year long treasure hunt around the world. It then shifts over fifteen years to the adventures of Fate Testarossa, Kid and Hinata's daughter and her friend Hibiki Tokai.
- Amagami: Atsushi Dojo just got dumped by Zeke on Christmas Eve. He then goes on with his life, while being annoyed by his younger sister Fiona, and can either romance his sempai Boota, his best friend Muroon, his kouhai Il (while her story was narrated by Peterhausen), another one of his kouhai Rinslet Walker, his childhood friend Sae, the class president Lala-Ru, or Stalker with a Crush Vivi.
- Angel Sanctuary: Yuji Kaidou wants to fuck his sister Mahoro Ando (oh and something about being caught in the middle of a war between Heaven and Hell).
- anohana: The Flower We Saw That Day: Ryoushi Morino, Suzaku Kururugi, Sumi Kuori, Ayase Aragaki and Phoenix Wright reunite after ten years to grant the wish of their deceased friend, Roman Saotome.
- Anpanman: Matilda Ajan fights the evil forces of Frieza and Bulma.
- Arakawa Under the Bridge: Tieria Erde falls into a river and gets saved by Ciel Phantomhive and becomes the latter's boyfriend in return. Kratos Aurion narrates.
- Arcade Gamer Fubuki: Hinaichigo is a girl that puts on panties to become a pro gamer. And faces off against people like Amuro Ray, Kirino Chiba and even Rider 1
- ARIA: ¡Three Amigos! Yamamoto, Subaru and Kyou work for a gondolier tour business under their respective mentors Yuko, Cornelia and Utena.
- Cat Planet Cuties: Toppa Bashin discovers Cat Girl Natsumi Hayamiya at his Grandfather's funeral. Military based hi-jinks with Lala Satalin Deviluke and Elea and (somewhat justified) cat girl harem ensure.
- Asura Cryin': Nuts and his childhood ghost friend, Ayame, find out from Mina that they can summon a giant robot thing. At the same time, a fire-throwing demon miko by the name of Ichijou comes into Nuts' life to help him figure out just what's going on.
- Attack on Titan: Shu Ouma lost his mother, Trisha Elric, when man-eating giants broke into the fortress city. He joins Yoko Littner, Kittan Bachika, Nezumi, Millais Alloy, Nice Holystone, Miku Hatsune, Yuki Sanada, Keima Katsuragi, Akari Akaza, Battler Ushiromiya, Koyomi Araragi and Toshiro Hitsugaya to defeat these monsters.
- Axis Powers Hetalia: Rock, Guile, and Katsuya Jounouchi unite to become the Axis Powers. They fight the Allied Powers, led by Kamina who controls Bloo, Gluttony, Vash the Stampede, and Shusuke Fuji.
- Alphonse is Edward's younger... sister?
- Azumanga Daioh: Child Prodigy Nel Tu goes to school and befriends Jerkass Shiho Nagaoka, Straight Man Princess Bubblegum, Motoko Aoyama, Cloud Cuckoo Lander Tsuruya and athletic Stella Lousier. They belong to Miyuki Kobayakawa's class. Also features a possibly-hallucinatory Coach Ohta who is a bird.
- Baccano!: Jadeite, Cream The Rabbit, Brief, Roger Smith and slew of others get in a slew of problems in prohibition-era America.
- Bakemonogatari: Nozomu Itoshiki finds himself helping Aika deal with a spirit problem by going to Guiche for help. He ends up helping Disc, Kivaara, Yuka and Mihoko as well. All while having to deal with his sisters, Naeka and Rimi at home.
- Bakugan: Grimlock enters the human world to keep Ian Vashti from destroying Vestroia. In order to do so, he has to work with Mariya Shido and her friends Marchis, Mifi Lotten, Rin, Le Chevalier d'Eon & Tails and fight Souichirou Nagi (Who's really Rin) & General Gil Dorom; Wataru Tachibana, Naviga Stelte & Perrine-H. Clostermann start out as villains, but eventually make a Face-Heel Turn.
- Bakuman。: Touma Kamijou decides to work as a manga artist with Sai in order to impress his friend Ikaros.
- Bamboo Blade: Down on luck Kendo instructor Ozma Lee assembles a team of female Kendo students including Tomoyo Sakagami, Arusu, Sora Naegino, Negi Springfield and Yumi Omura.
- Beast Wars II: Chirico Cuvie and his team fight the evil forces of Gouzaburou Kaiba, Japan & Helios (and their lackeys). Tomo Atoda and Metabee watch from outer space.
- Beelzebub: Young delinquent Cat is forced to become the surrogate father of Anti-Antichrist Dead Master.
- The Big O: Ayame Sohma is a skilled negotiator who's often accompanied by his Robot Buddy Relena Darlian. He frequently runs afoul of Makoto Kino.
- Birdy the Mighty:
- OVA Series: Space Police officer Usagi Tsukino accidentally kills Kensuke Aida while chasing after an intergalactic criminal, and winds up Sharing a Body with Kensuke until she can shut down their syndicate, ran by Sharon Apple. Solid Snake, another member of the syndicate, at one point breaks Usagi's arm, C.C. is interested in Kensuke, and Apolline Faria is Kensuke's sister.
- Decode: Same premise and the crime syndicate's still ran by Sharon (though she's not seen as much this time), but the Space Police officer is Ruby Tojo and she has an Idol Singer disguise, the kid she accidentaly kills is Haku, it's Jet Black who breaks Ruby's arm, Nowa is Haku's sister, Amu is just friends with Haku, and Rip Van Winkle is Haku's love interest. Additionally, Nick Carlyle is a TV producer with Social Darwinist tendencies. In the second season, it's revealed that Ruby was friends with Teru Mikami and Teru's taking care of Melfina.
- Black Lagoon: Italy, Dawn, Sanji, and Inspector Runge form an unlikely team against gangs of terrorists and Neo-Nazis. Lunch is a Russian mafiya boss who occasionally hires them.
- Black★Rock Shooter (OVA): Nadeko Sengoku must travel to another world to rescue her best friend Celty Sturluson. Meanwhile, Sengoku's other friend, Ku Fei may or may not be involved in the other world.
- Bleach: Meia Gisborn has a chance encounter with Auel Neider during a mission. After getting injured, Meia temporarily passes her powers to Auel to substitue for her. Eventually, they are joined by Barrier Maiden Alisa Boskonovitch, big guy Germany and Archer Archetype Rivalz. And that... is the first arc.
- Soul Society arc: Meia is taken away with her Aloof Big Brother Alucard and his lieutenant Chester Burklight. After much training with Trickster Mentors Lockon Stratos and Kaname Chidori, Auel went to kick some ass through a squad of elite fighters which contain the likes of Nanaly Fletch (with Gran Bruce as her lieutenant), Shadow the Hedgehog (with Jonathan Morris as lieutenant), Judith (with C.C as lieutenant), Akechi Mitsuhide (with Ciel as lieutenant), Doggie Kruger (with Chimatsuri Doukokuu as lieutenant), Solid Snake (with Margery Daw as lieutenant), Shagia Frost (with Altair as lieutant), Finn the human (with Neon as lieutenant), Nightmare (flanked with lieutenant Hwang Bu-Ling, 3rd seat Haken Browning, 5th seat Roy), Freeza (with Rise Kujikawa as lieutenant), and the lieutenant-less Squall Leonhart. Though in the end, it turns out these are a grand plan for Mitsuhide, Shadow and Shagia to betray their squad.
- Vizard arc: Zelos Wilder barges into Auel's life and tells him that he is part of him. He drafted him to train together with the likes of Cassandra Alexandra, Brooklyn Luckfield and Captain Commando. On the other hand, a reconnaissance squad of Mitsuhide's forces, led by Yuu Narukami, Iron Tager and later a VERY PSYCHO Archer, which ends up in Alisa being captured (in which Archer kills Edge Maverick for lulz).
- Hueco Mundo Arc: Auel, Rivalz and Germany barges in to Mitsuhide's realm to save Alisa, meeting up with Meia and Chester, alongside Chiyo Miyama. On the other hand, Mitsuhide assembles a group of elite Arrancars, but only sends out Yuu (knocks Auel out), Thouzer (beaten by Nightmare), Archer (beaten by Auel), Yuri Lowell (beaten by Freeza), Rude (beaten by Alucard) and Rau le Creuset (beaten by Meia). But it was only a discretion so Mitsuhide could advance to the next stage...
- (Filler) New Captain Arc: In some sort of an Alternate Universe, the empty seat of Shadow is replaced by Captain America who also brought in his 3rd seat Asakim Dowin. Conspiracy around a princess named Kaolla Su happens and it is later revealed that both Cap and Asakim are the actual antagonists. They're swiftly killed and Cap hits the Ret Gone button on him.
- (Filler) Zanpakutou Rebellion Arc: Graham Aker causes a rebellion within enemy weapons, causing the weapons, consisting Faize (assisted with Vita, they were created by splitting off Ingram Prisken), Susanoo, The Edel Bernal, Ashelia B'nargin Dalmasca, Reizei Abane, Litchi Faye-Ling, Aya Shameimaru, Eko (without Kaz), Akuma, Apollo, Honda Tadakatsu. Graham's plan is to revive Dio Brando, an ancestor of Alucard, but then Dio backstabs him and is beaten by Alucard whereas Auel, after taming his Wanyuudo, gave Graham death, after the rest of the weapons became tame once more.
- Beast Sword Arc: After Dio and Graham's demise, things has yet to calm down as other 'released spirits' are still out to wreak havoc. The good guys and their weapon spirits try to quell the chaos, although Litchi ends up striking a tragic relationship with Leonhardt Raglen. All the troubles eventually led to Albert Wesker, and after taking him out, most weapons spirits return in peace for good.
- Fake Karakura Town Arc: The good guys consisting Shanoa (a replacement of Nanaly), Jonathan, Ciel (arriving late), Doggie, Doukokuu, Snake, Altair, Ed, Neon and Squall face off against Mitsuhide's bad guys spearheaded by Wolverine, Mons Drake and Princess Emeraude. In the meantime, Auel had his final showdown with Yuu, while Alucard and Raoh team up to beat Tager. Lots of bad guys die... including Shagia.
- Deicide Arc: The good guys fell thanks to Mitsuhide's power, even with the help of Lockon, Chidori and Auel's father Kyosuke Nanbu. Shadow betrayed Mitsuhide only to be killed, but then thanks to a Training from Hell provided by Kyosuke, Auel managed to kick Mitsuhide's ass (after transforming Wanyuudo into Yosuke Hanamura).
- Substitute Shinigami Arc: Auel thought he's had his normal life again while helping Matsu run her unagi shop... until he's confronted with Ovan to confront his brainwashing friend Nameless, who's had his sights on everyone Auel dears on. With the help of Ovan's friend, Aqua, Auel retrains for battle again... Ovan is also a Big Bad like Nameless.
- Final War Arc: Not going to be animated, but still... after surviving the Fake Karakura arc, Emeraude has been kidnapped and Chiyo had to drag Auel to beat her captors.
- Bleach movies:
- Memories of a Nobody: Auel attempts to stop Sazh Katroy to sacrifice Hitagi Senjougahara to achieve his utopia. Sazh is beaten, but Senjougahara still dies and reincarnates.
- Diamond Dust Rebellion: After Finn is accused of treachery, Auel tried to solve the mystery of it, only to find Finn's old, vengeful friend Kuja behind this.
- Fade to Black: Meia has brothers and sisters in form of Nozomu Itoshiki and Haruhi Suzumiya. But now they're erasing Auel's memories and wants to keep Meia only for them...
- Hell Verse: Ribbons Almark kidnapped Auel's sister and Auel must save her, helped by Date Masamune. However, Masamune was actually the mastermind of the whole event.
- Blood-C: Lan Fan is a miko who battles vampire-like creatures.
- Blood+: After being saved by Kamina, Ami Kawashima discovers that she has vampire-like powers and, with the help of her best friend Yoshimori, she must fight her Evil Twin, Relena Peacecraft.
- Bludgeoning Angel Dokurochan: Mio Sakamoto repeatedly turns Cassandra Alexandra into a bloody mess and then resurrects him for laughs. Taiga Aisaka wants to end Cassandra's suffering but she continually fails at that.
- Blue Exorcist: Accelerator learns he and his genius brother Lelouch are the sons of Satan, which unintentionally causes their surrogate father Maes Hughes to die. He goes to a school run by Izaya to learn how to become an exorcist.
- Bobobo-bo Bo-bobo: Excalibur, Kafuka Fuura, France, Cagalli Yula Attha, Seto Kaiba, and Chiyo Mihama all fight an evil empire.
- Brave 10: Snow Villiers is constantly being pestered to protect by shrine maiden Yui Emelia Mitsukihara, which culminates him staying along with the famous general Charlie Nash who employs 'ninja/assassins' like Jin Kisaragi and Rider (Snow's childhood friend) and recruiting some more, all while dealing those who wants to capture Yui Emelia, which includes ninja Cloud Strife and one-eyed general Tekkaman Evil
- Busou Renkin: After being killed by a homunculus, Lelouch Lamperouge is revived by a strange heart implant that doubles as his signature weapon. His partner-in-action, Ino Yamanaka, fights against the homunculi with a series of blades hidden beneath her school uniform.
- Canaan: Beginning professional photographer Aiko Kudo travels to Shanghai to meet Asami Iwasawa, a girl who saved Aiko before. Crona targets her, causing Asami to rescue her again. Every now and again, Giroro shows up as a Taxi driver.
- CLANNAD: Graham Aker has a change encounter with Rena Ryuuguu, who is interested in reviving her school's drama club. Graham's buddy Jacuzzi Splot gets beaten up a lot.
- Chobits: Kyon discovers Lacus Clyne in the trash, and eventually begins to develop feelings for him.
- Chousoku Henkei Gyrozetter: Shockwave recruits Rio Rollins, Nick, Magellan, Index and Masumi Kotsu to fight the evil forces of Starscream and his henchmen Nils Nielsen and Hatsune Miku. Leonidas and Sei also turn up to help the heroes.
- Code Geass: Watanuki teams up with mysterious waif Meiling to form a guerrilla army so they can make the world a better place for Eureka. Along the way they team up with Tenma. However, Chiyo's Dad has other plans.
- Cowboy Bebop: Ryoga Hibiki, Professor Oak, Rei Ayanami, and Terriemon are bounty hunters who try to make a living while avoiding Ryoga's greatest enemy: EMPEROR CHARLES ZI BRITANNIA.
- Dangan Ronpa The Animation: Shinji Ikari, Yuri Lowell, Milla Maxwell, Viridi, Suzaku Kururugi, Teddie, Homura Akemi, Hanataro Yamada, Maria Cadenzavna Eve, Ellen Kurokawa, Date Masamune, Orochimaru, Amane Nishiki, Teru Mikami and Hikaru Shidou are all in a Gilded Cage school where the only way to escape is to kill someone without being found out. The school's headmaster? Doraemon.
- Dead Leaves: InuYasha and Princess Luna find themselves in a prison, staffed by Wheeljack and Baltro.
- Death Note: Death the Kid finds a mystical artifact that causes people to die if their name is written in it. Usopp, the world's greatest detective, tries to stop him. After Usopp dies, Akane Tendo and Oz take his place.
- Deltora Quest: Kakeru Nohara is joined by swordsman Senbei Norimaki and wild girl Erika Karisawa on a quest to free the land from Ultra Magnus.
- Detective Conan: Sai Saici is a well-known teenaged detective until Dodoria and his partner Gendo Ikari drug him and becomes Kiki. She's then taken in by Shukyuu & Kenshiro and is also joined by Faye Valentine (who also shrunk), Genma Saotome, Garv, officer Bellamy and many others.
- Digimon Tamers: Rudy Tabootie, Chun Li, and Envy are paired with Merryweather, Arisa Uotani, and Ed.
- Dirty Pair: Holi and Kodachi Kuno who accompanied by their pet Gunmax, are a pair of detectives whom leave a trail of (mostly accidental) destruction in their wake.
- Dragon Ball: Guilmon meets Meryl Stryfe who ropes him into a search for the Dragon Balls so she can wish for the perfect man, however in order to gather all seven they must contend with the shape-shifting pig Dr. Escargon, desert bandits Amuro Ray and Guu and most notably, Buggy the Clown and his bumbling minions Gin and Suppaman. After summoning the Dragon Alex Louis Armstrong, Guilmon heads out on his own to train under Chang Ang alongside Koenma.
- Dragon Ball Kai: After alien invaders, Captain Falcon and Mr. 1 kill several of Guilmon's allies, the remaining heroes must venture into space to gather the Namekian Dragon Balls. Unfortunately, they are unaware that someone else is after these mystical artifacts, the most fearsome dictator in the galaxy, "Him".
- Dragon Crisis!: Keima Katsuragi is an ordinary high school student until C.C., his second cousin returns from America forcing him to join her unauthorized organization. The two intercept a trade and discover what was being traded - Ruby Gloom.
- Durarara!!: Tayura Minamoto, at the invitation of his friend Light Yagami, transfers to a school in Tokyo. Tayura then witnesses an urban legend on his first day in the city: a headless Satanic baby.
- Eureka Seven: Kazue Nanpo falls in love with mysterious mecha pilot Tsubaki and joins an anti-military group including Satella Harvenheit, Jake Martinez and Etemon.
- Excel Saga: Boa Hancock and Euphemia li Britannia are two agents of Excalibur, who intends to take over a city.
- Fairy Tail: Haruhi joins with Simon and the Palmtop Tiger to save the Wizarding World alongside Beatrice and Iceman Hotty.
- Fist of the North Star In a post-apocalyptic Earth previously ravaged by nuclear war, Ryo Saeba, successor to the deadly Hokuto Shinken martial art style, emerges as its savior. With his traveling companions Masao-kun and Jirachi, he initially travels to win back his love Sally the Witch, who was taken from him by friend turned rival, Nanto Seiken practitioner Piccolo. Later, he encounters opposition and assistance by several other Nanto Seiken masters: D, Liquid Snake, Go Mifune and Zack. Also, he reunites with his brothers and fellow Hokuto Shinken practitioners, the heartless Takeharu Kirijo, the benevolent Severus Snape, and the ambitious Braiking Boss, who seeks to become the soul Hokuto Shinken master and ruler of Earth/The Heavens, establishing himself as the Big Bad.
- Fruits Basket: Naru Narusegawa is a girl who ends up as a live in maid with Keroberos the rat, Hiromu Shinbo the cat and Byakuya Kuchiki the dog. Other members of their family include Sailor Moon the boar, Honey the rabbit, Kakashi Hatake the seahorse, Roger Klotz the cow, Simba the snake, Miyu Kozuki the tiger, Ibuki Yagami the ram, and Ellonwy the monkey. Naru's best friends are former gang member Angel Salvia and psychic Ran Tsukikage.
- Fullmetal Alchemist: Temari and her younger sister Shana attempt to get their bodies back by using a mysterious stone. Along the way, Tinky Winky wants to kill them.
- Full Metal Panic!: Shinichi Chiaki is a Child Soldier who is assigned, alongside with his team mate Roy Mustang and leader Agnes Chevalier de Milan, by Inspector Yokomizo to guard Kagome Higurashi from overseas threats. Meanwhile, Inspector Yokomizo works in a highly advanced submarine with its captain C.C. and her executive officer Edward "The Elder" Hamilton to eliminate the source of those threats.
- Fushigi Yuugi: Felicia and Urd get sucked into the novel's universe, but Felicia gets stuck into said universe and she later falls in love with Zelgadis Greywords. The other Suzaku warriors includes Il Palazzo, Sailor Star Healer, Sousuke Sagara, Knuckles, Yamazaki and Utena, who must defeat Millions Knives and his minions.
- Future GPX Cyber Formula: Harley becomes a racer after he rescues Mr. 11 from thieves. Sailor Moon is a race queen and Heero Yuy, Mousse, Sosuke Aizen, Broly, Zero and Oolong are also racers.
- Gankutsuou: A version of The Count of Monte Cristo IN SPACE!! Lelouch and Makoto Ito are best friends who meet Albert Wesker one night at a space party. Murder ensues.
- Gintama: Ragna the Bloodege, Jacuzzi Splot, Tsukuyomi, and their gigantic dog Montmorency, take various odd jobs in order to pay their rent from the landlord, Orochimaru.
- Girls und Panzer: in an interschool competition in which teams of girls operate tanks, one team consisting of Alice Yotsuba, Maomin, Keiko Totsugawa, Oriha and a gunner competes with their school's existence at stake.
- Glass Mask (1984): Alordayne Grotke is girl with a dream to act, so she runs away from home to attend an acting school. Her talent is noted by the Makaiju, and wants Miss Grotke to ressurect the role in a play she was going to star in before a stage accident and health problems made her stop acting. However, Makaiju also has her eyes on professional actress Lulu, who just wants to succeed on her own.
- Great Teacher Onizuka: Masaru Aoki is an ex-delinquent who became a high school teacher. Among his class are Teen Geniuses Heero Yuy and Sailor Moon, Momma's Boy Sousuke Sagara, ditzy Saber, Recca who's always bullied by Nami, and Aoki's constant antagonist Veemon.
- Grenadier: Busty Gunslinger Caro Ru Lushe is on a journey to learn the Ultimate Battle Strategy. She is joined by Samurai Mugen and Balloon Maker Ayumu Kasuga.
- Gundam Build Fighters: Joey is good Gundam builder but is a terrible fighter. Weed suddenly joins him to help. Mikasa then also joins Joey, along with Tomoya and Ryuji as a scientist.
- Hajime No Ippo: Kaoru Kaidou is being beaten up by Kaname Ohgi and his pals when pro-boxer Reiji Takayama intervenes. Takayama took Kaido to the gym and from then on, Kaido decided to become a boxer to discover the true meaning of strength.
- Heartcatch Precure: Shy flower girl Tsubasa Kazanari gets to be "The Weakest Magical Girl Ever" and work her ass off to become competent in fighting monsters under Zasalamel and his 'daughter' Pit, along with Quirky Miniboss Squad Francis Drake, Ishida Mitsunari and Warz Gils, working under Pegasus Kouga to prevent them to turn the world into desert, also helped with her fashionista Juliet, Wholesome Crossdresser student council president Cliana Rimskaya and the legendary former Magical Girl Brought Down to Normal Judith.
- Hellsing: Edmond Dantes is a vampire under the control of Queen Nehellenia. Along with Roeas' Battle Butler Norman Burg, they fight people such as Father Onsokumaru.
- Hidamari Sketch: Kiyal gets into the art department of a private high school whose principal is the constantly-trembling Nanomon, and moves into the apartments across the street, where she befriends fellow first-year Pepper, and their sempai, the motherly Mikuru Asahina and more reticent flat chested Meganekko Milfeulle Sakuraba. (The apartments, incidentally, are run by Puchiko.) The first-years have Choppy for an art teacher. Milfeulle is occasionally visited by little sister Ikuto Noguchi, and has a rivalry with Golden Darkness. When they move up to the next year, the four are joined in the apartments by new first-years Menoly, who's in the art department, and Maka Albarn, who's not.
- High School DXD: Hope Estheim gets killed by Yukiji Katsuragi but gets revived as a devil by The Literature Girl. She then invites him on her club composed of herself, Kaori Kanzaki, Serph Sheffield, and Tsubaki. They're latter joined by Yukiho Hagiwara.
- High School Of The Dead: Archer, Senou Natsuru, Guy Shishioh, Nia, Celty Sturluson, and Karen Araragi fight zombies.
- Higurashi: When They Cry: Kira Yamato, Sernia Iori Flameheart, Kagome Higurashi, and Yamada are all stuck in a murder mystery.
- The iDOLM@STER: Join Kouji Kabuto as he is drafted by Jiraiya to produce Idol Singer like overly average Enjutsu, super-serious-in-singing Kurisu Makise, super-shy formerly-known-as-Thursday the Robot, hyperactive Lilica Felchenrow, ditzy Litchi Faye-Ling, haughty little Ojou-sama Rise Kujikawa, tomboyish Kamui Tokinomiya, twin girls Rin & Len Kagamine, amongst others... He is also assisted by Princess Elincia of Crimea as his secretary, and must also endure the antagonism made by Lezard Valeth.
- Infinite Stratos: Ventus is tutored by Aqua and Sakura Matou on how to pilot a Powered Armor. Ventus must also deal with the hearts of his fellow colleagues Maya Kumashiro, Mezool, the Futami twins, Black★Rock Shooter and Yoko Littner, all pounding on him like Heartless.
- Inuyasha: Usopp, a half-demon living in Feudal Japan, falls in love with Milly Thompson, a high school student who finds herself transported back into the past. Along the way, they befriend perverted monk Justy Ueki Tylor, mighty demon hunter Kagura (who falls in love with Tylor), and the fox demon Sgt. Keroro. They also frequently encounter Usopp's brother Jeremiah "Orange-kun" Gottwald and the prideful wolf demon Kindaichi. They're doing all of this to stop the demented Sephiroth.
- K: Italy is being chased two opposing groups, the Red clan (led by Seto Kaiba and composed of Suzaku Kururugi, Maria Ushiromiya, Kimihiro Watanuki and Alto Saotome) and the Blue clan (led by Gintoki Sakata and composed of Celty Sturluson and Light Yagami). Then, he meets Sebastian Michaelis and Marika Katou.
- Kaiketsu Zorori (Series): Genie wants world domination.
- (Film) Iago becomes a wizard's apprentice to try and achieve world domination.
- Kämpfer: Rei Miyamoto is an ordinary high schooler who finds out she can turn into Yoko. She fights other people with her friends Cutie Honey, Nanoha, and Carly.
- Kazemakase Tsukikage Ran: Saki Hanajima is a Sake loving female ronin who is joined by martial artist Nami.
- Kenichi: The Mightiest Disciple: In order to become stronger, Domon Kasshu trains with Rosette Christopher, Hoody, Arlong, Koji Kabuto, Alex Rosewater, Yusaku Godai and Ai Enma.
- Kill la Kill: In order to find her father's murderer, Kallen Stadtfeld along with her talking uniform Genjo Sanzo must face The Great And Powerful Trixie and her Absurdly Powerful Student Council consisting of A-ou, Black Wargreymon, Ox Ford and Haruko Haruhara.
- K-On!: Su, Aine Shizuma, Satan and Serah Farron join a light music club. Vita is their teacher, and Ako later joins the gang.
- Maid-Sama!: Seikon No Qwaser's Mafuyu is the student council president of a formerly all-boys' school, but has a part time job as a maid at a cafe run by Otohime. She may or may not be falling in love with Leicester Maycraft.
- Kyattou Ninden Teyandee: Inuyasha, Ryoko and Arlong are feline ninja who fight an evil band of ninja crows led by Spike Spiegel while working at a pizzeria.
- Kyousogiga: Shana went to Mirror Kyoto with Near and Hayate Ayasaki where she meets Trowa Barton, Saya Otonashi and Shinn Asuka, who are protectors of the city and waiting for their parents, Cerberus and Athrun Zala. She also meets Homura Akemi, and her assistant, Miles Edgeworth.
- Legend of Galactic Heroes in the future, where mankind has expanded far beyond the confines of Earth and are in midst of war between two factions, Vegeta, a poor, but ambitious noble from the Galactic Empire, sets out to lead the Empire and unite the Universe under his rule. He is assisted mainly by his childhood friend and close subordinate Wingwaver, and his handpicked squad of talented commanders. Chief among them are his earliest followers Chiyo's Dad and Ken The Eagle. Meanwhile, on the other side, Duke Fleed of the Free Planets Alliance, a gifted tactician and Vegeta's eventual Worthy Opponent, and is tasked with defending the Alliance along with fellow solders Jerrid Messa, Kai Shiden, and later his adopted son Tetsuo Shima, among others.
- The Legend of Koizumi OVA: Former Japanese prime minister Sephiroth delegates with Korean leader Brook and his son Eikichi Onizuka using mahjong. Later, Sephiroth delegates with Chinese leaders Liquid Snake and Dr. Riddles, which takes a turn for the worse when Communist leader Raoh is brought back from the dead.
- Les Miserables Shojo Cosette: Ray Lovelock is being chased down by Takeo Saeki and he adopts Empress Tianzi who later grows up as Nunnually vi Britannia and falls in love with Motoharu Tsuchimikado.
- A Little Snow Fairy Sugar: Orderly 11-year-old Marguerite has her plans turned upside-down by a little fairy named Madoka Fujisaki, who has the power to make snow. They are soon joined by wind fairy apprentice Laharl and sun fairy apprentice Emilio, and all of them have taken up residence in her home, where she lives with her grandmother Takako Inubushi. Part of the problem is that she's the only human around who can see and hear them. The three need to find a "twinkle" in order to become full-fledged season fairies of their respective types, but they cannot find out what it is, and indeed, have different ideas of what it's like... not to mention that Elder Cerberumon isn't helping much, especially given his fixation on the romantic pursuit of full-fledged rain fairy Excel, who in turn, seems to have an interest in cloud fairy Waspinator, who just wants to make the perfect cloud. Mixed up in all this craziness are Marguerite's friends Chiyo and Kayo Ando, inventor Sawako Yamanaka, and Rich Bitch and self-proclaimed rival President Aria.
- Lost Universe: Goku and his Spaceship Girl Lime roam the galaxy fighting evildoers, one of whom happens to be Gourry Gabriev.
- Love Hina: Takeshi lives with his Cool Big Sis aunt Lina Inverse, and is surrounded by hot chicks such as Ayu, Lumine, Kaname, Sakaki, Rakshata and Hiyori.
- Lucky Star: Kaoru Akashi, Hyper Blossom, Koromo and Sheryl Nome indulge in nerdy pursuits.
- Lupin III: Dr. Mashirito, Watari, Captain Harlock & Honey Kisaragi are a quartet of thieves that constantly get chased by a pissed off Grand Lord Crisis.
- Madlax: Legendary mercenary Asuka Tenjoin and wealthy heir Princess Shoukei, two females who have little memory of their pasts, team up and investigate Norbert, who's taken interest to them.
- Magical Girl Lyrical Nanoha: Rozalin attempts to befriend Neige Hausen who is suffering from her mad mother Hawkgirl.
- Magical Girl Lyrical Nanoha A's: Rachel Alucard found out a sealed book which contains a sealed Franziska von Karma, along with her guardians Dejiko, Lamia Loveless, Reala and Asura. Rozalin and Neige try to befriend them.
- Magical Girl Lyrical Nanoha StrikerS: Rozalin, Neige and Rachel formed a squadron consisting Taokaka, Reimu Hakurei, shota version of Yoko Littner and Heart Aino. They stumble upon Norma Beatty and has to protect her from the forces of Johnny Bravo.
- Mai-HiME: May Wong, Nina Einstein and Suzuka Tsukimura are among a dozen girls sent to school to fight shadowy demons...a school run by three-hundred-and-eleven-year-old Tessa Testarossa. Kaworu Nagisa sticks around to watch the chaos unfold.
- Mai-Otome: Mokona enrolls in a Magical Girl Warrior academy, but her powers can only activate with the help of fake princess C.C.. Holo the Wise Wolf is Mokona's #1 rival, and the adopted daughter of Kamina, who is working under the strict orders of the tyrannical Athrun Zala. Yomi, the school's #2 student, is jealous of Mokona and Holo to a homicidal degree (especially Mokona).
- Mazinger Z: Emperor Daibazzal, a megalomanaical Mad Scientist, sends his henchman who is half Silene and half King Bradley with an army of mechanical monsters to wreak havoc. The only one who can stop them is Apachai Hopachai piloting a giant robot invented by his late grandfather. Joining him are Alexandria Meat whose robot fires breast missles and Kazuto Nagano who gets his own robot.
- Midori no Hibi: Kittan is a tough fighter who just wants to have a girlfriend. Without any explanation, his right hand becomes Mai Tokiha.
- Minami-ke: Negi Springfield, Erio Mondial, and Sakutaro are siblings and are engaging normal lives.
- Mnemosyne: Private investigator Ai Enma and her assitant Shana happen to be an immortal couple.
- Mobile Suit Gundam: Pegasus Seiya gets drafted into Banjou Haran's battleship to fight against Souther's empire, whose dragon is Hiko Seijurou, who plots to overthrow Souther's empire (and he's done that to Souther's brother Ken The Eagle). Seiya gets slapped to shape by Banjou. Both Seiya and Hiko fell for Athena, but then Seiya accidentally killed Athena.
- G Gundam: Viewtiful Joe travels around the world with Kiyone Makibi to look for his brother Bartholomew Kuma. Giant robots are involved.
- Mobile Suit Gundam Wing: Tamahome was sent to Earth for a mission. He was attacked and was found by Maya Amano and she developed an attraction to him. He doesn't seem to like it and he threatens to kill her. On missions, he is eventually accompanied by his comrades Mousse, Android 17, Max Mizuhara and Chousokabe Motochika.
- After War Gundam X: Eikichi Onizuka rescues Vanilla H and joins Pain's gang. They are constantly persisted by brothers Naraku and Yusuke.
- Mobile Suit Gundam SEED: Childhood friends Narutaki and Coud are forced to fight each other in war. They eventually join forces.
- Mobile Suit Gundam Seed Destiny: Coud returns with his girlfriend Shizuru to have a peace meeting with PLANT chairman Shanks, but the trio of Grimmjow, Tidus and Kagura led by Ran "Aya" Fujimiya, stole three mechas and caused havoc. Coud decides to fight, but is outnumbered. Luckily, Lavi came to his aid, along with his pals Hitomi and Sanzo.
- Mobile Suit Gundam 00: Season 1 features Riku, Takumi Fujiwara, Hibiki Tokai and Nozomu Itoshiki fighting all factions of the world to unite them. Season 2 features Riku reuniting with Sora and eventually co-piloting the titular machine. The machine is armed with GN Swords and The Power of Friendship. Together with their new teammates Kisuke (Takumi's Backup Twin) and Cheza (Hibiki's girlfriend), they fight Yamcha and his sissy goons.
- My Neighbor Totoro: Akane Tendo and Nuriko have strange and wonderful adventures when they move to the country with their dad, the mastermind who brought you Giygas. Said mastermind's wife is Kanata Izumi.
- Najica Blitz Tactics: Sally Poe is an undercover secret agent who's day job is a perfume worker. While on a mission, she encounters Sumomo, a highly advanced android. Gratuitous amounts of Fanservice ensure.
- Naruto: Rika Minami, Bad Girl and England are three ninja in training under November 11 in order to become master shinobi. At the end of the seres, England does a Heel-Face Turn and joins Otose in order to kill his brother, Auron. Bad Girl decides to train under Reiko Kashiwara in order to get stronger. And Rika leaves the village to train with Xigbar.
- Naruto Shippuden: After training with Xigbar for three years, Rika returns and, with new comrades like Saito and Shinigami-sama, she searches for her friend England. She is also being persued by a sinister organization led by Raiden, who is really working for Hayato Jin who is disguised as Jan Valentine. Also, Rika later finds out that her parents are Ryu and Sailor Jupiter.
- Later in the series, Rika trains with Geki Hyuuma to try and gain control of her Superpowered Evil Side, Optimus Prime.
- Neon Genesis Evangelion: Three unstable teens—shy Yukito Tsukishiro, brash Casca, and seemingly emotionless Lina Inverse—are forced by ruthless leader Don Krieg to battle "Angels" while under the command of Sailor Moon.
- Nightwalker: Vampire Detective George De Sand is joined by agent Makoto Kino, Girl Friday Haruhi Fujioka and imp Dot Warner.
- Nogizaka Haruka no Himitsu: Arcueid's brother and Kaolla Su's friend is a real estate agent who has to protect a secret of crossdressing Johan Liebert, who once won a piano contest against Negi Springfield. Nena Trinity is also involved. This won't end well...
- Noir: Professional assassin Juri Arisugawa and an amnesiac Wendy Garret get tangled with organized crime and international conspiracies as they discover more about each other's pasts.
- No Matter How I Look at It, It's You Guys' Fault I'm Not Popular: Rainbow Dash, a deranged and anti-social shut-in, desperately tries to find ways to become popular.
- Ojamajo Doremi: Hinako, a clumsy and hyper elementary school student, becomes a witch apprentice after discovering that Zim is a witch. After her best friends, brainy Suzume Mizuno and athletic Osakan transfer student Tsuruya find out her secret, they become witch apprentices, too. They also recieve their own fairies: Hinako gets clumsy Tailmon, Suzume gets kindhearted Angela Moore, and Tsuruya gets tough Riff-Raff. Later joining the team is Hinako's little sister, Ikue Ogawa. They gain a rival witch apprentice, Sakurako Sanjo, under the apprenticeship of Zim's rival, but later joins the team. A later addition to the girls is Japanese-American transfer student Rolling Bubbles. The girls have to take care of a baby from the witch world as well, Nowi, who uses magic to age up into an eleven-year-old.
- One Piece: Krillin starts his own pirate crew, recruiting swordsman Date Masamune, navigator Saturn, sniper Kyle Broflovski, chef Wild Tiger, doctor Pikachu, archaeologist Ritsuko Akagi, shipwright Yoki and musician Kim Jong-il. Eventually they are split up by Captain Ginyu and Krillin must save his brother Ataru Moroboshi from being executed.
- Oreimo: Greed can't believe that his sister Ako Suminoe can be this cute and perverted.
- Ouran High School Host Club: As punishment for breaking an expensive vase, Hitomi Kanzaki is forced to join Death the Kid's "Pretty Boys" club to earn her keep. Members of said club include Mikami Teru and Shiki Tohno (who is part of a pair of incestous twins).
- Paprika: Musashi and Batou try to figure who stole a dream-seeing device built by Tuxedo Mask ( It's Gin and his lackey Ryoga Hibiki!), with the help of Musashi's alter-ego, a perky red-headed Rei Ayanami.
- Panty & Stocking with Garterbelt: Loveable Sex Maniac Holly Jones and Elegant Gothic Lolita Mika Harima are two angels sent to battle ghosts (including spectral Chihuahua Nanao Ise) under the command of Kotaro Taiga. They are later helped out by Firo Prochainezo who has a crush on Holly, and later fight two demon sisters, Cure Passion and Niche, and their boss, Discord.
- Pokémon: Ryou Bakura goes on a journey to become a Pokémon master, with Tron Bonne and Keitaro Urashima providing support. Constantly they're hounded by Lina Inverse, Roy Mustang, and Manta Oyamada who are constantly trying to steal Tony Tony Chopper. An egg later hatches for Tron Bonne, revealing Snarf. Keitaro takes a break during season 2, and Mepple fills in.
Eventually, Tron Bonne is replaced by Nana "Hatchi" Komatsu and Pekkle. In turn, they are eventually replaced by Revy. Then they and Keitaro are replaced by Madoka Kaname and Death the Kid. Madoka and Death the Kid are then replaced by Eren Yeager, his little sister Urara Kasugano, and Yuri Usui, a childhood acquaintance of Bakura.
- Prince of Tennis: Oz Vessalius joins the Seigaku tennis club led by Zero. Also in the team are his sempai and constant companion Vash, prodigy Kurapika, Awesome by Analysis Seto Kaiba, Keet and doubles genius Impmon and grumpy Ippo.
- Psycho-Pass: Kobato joins the police force which is composed of Gilgamesh, Ryuunosuke Uryuu, Lenalee Lee and Szilard Quates and led by Fumito Nanahara.
- Puella Magi Madoka Magica: Iris and her friend Saya Takagi are approached by Kagami Hiiragi, who offers to grant them each one wish in return for making them magical girls. Natsumi Hinata, Navi, and Konoka Konoe are also major characters. Navi gets eaten horribly, And There Was Much Rejoicing among Zelda fans.
- Queen's Blade: Saber, Nyamses, Satellizer El Bridget, Sanada Yukimura, Routier, Amu Hinamori, Rushuna Tendo, Sayaka Miki, Vivio Takamachi, Eruru, Waffle, Selveria Bles, Marida Cruz and Lacus Clyne battle it out to see who would become the next queen. Seikon No Qwaser's Ekaterina "Katja" Kurae is the one who foresees the match.
- Ranma ½: L is an expert martial artist who turns into Lina Inverse when splashed with water. Near is a tsundere. They are thrown into an arranged marriage by their fathers (King Dedede and Exsedol Folmo, respectively). They aren't too keen about this, and neither are their various suitors (which include Yubel, Spike Speigel, Giovanni, and Yuri).
- Rosario + Vampire: Souichi Negishi, due to a mix-up, is sent to a school for supernatural beings. He falls in love with Fate Testarossa, although other students (such as Golden Darkness, Sora Kitano, and Alphonse Elric) also want to jump his bones.
- Saber Marionette J: On a planet populated by men, Wakaba Shinohara, a poor but hard-working young man, finds himself with three female androids: Genki Girl female Ranma, Yamato Nadeshiko Sayo Aisaka and Yukari Tanizaki.
- Saki: Hayate, Boota, Lelouch, Kallen, Shana & Rin get together and play Mahjong.
- Sakura Diaries: High School Graduate Kaname Ohgi seeks to enter a prestigious university but ends up in a triangle between classy beauty Martel and his cute cousin Yurika Dojima.
- Sailor Moon: Mink learns from Professor Ivy that she is a Magical Girl. She makes friends with four other similar girls: brainy Nyamo, fiery C-Ko, Misaka Mikoto's mother (who can shoot lightning like her daughter), and ditsy Fran. Mink later falls in love with Amuro Ray and meets her future daughter Felecia. Eventually, Mink meets several other magical girls who work on a separate team: Shinji Ikari and Lady Tsunade (who are in love with each other), the guardian of the Time Gates Hikaru Makiba, as well as the emissary of destruction Pan.
- Saint Seiya: Tuxedo Kamen, Bright Noa, Robert Device, Heiji Hattori and Schwartz Bruder are young warriors who fight for Luna, who happens to be the incarnation of the goddess Athena.
- Saiyuki: Journey to the West, featuring a Jerkass Duo Maxwell, Keet Kira Yamato, Team Mom Kuja and Chivalrous Pervert Sanji, ordered by an ambiguously good Precia Testarossa to retrieve an artifact stolen by Caster. Barring their way is a group of Punch Clock Villains consisting of Noble Demon Ky Kiske, little Itsuki, Yamato Nadeshiko Hotaru Tomoe, and Big Brother Mentor Jotaro Kujo.
- Samurai Champloo: Saber manages to trick Roronoa Zoro and Saix into becoming her bodyguards in order to find a mysterious samurai.
- Science Ninja Team Gatchaman: Earth is threatened by the Galactor terrorist organization, who plots to steal the world's natural resources and eventually become its sole ruler. In response, Darth Vader of the International Science Origination deploys the Science Ninja Team as the counteroffensive, led by the heroic Nephrite and consisting of Doctor Mochizuki, rebellious 2nd in command, Celebi, the sole female, Cosmo Yuki, Celebi's adopted kid brother, and country boy Big Guy Ibuki Yagami's Dad.
- Seikon No Qwaser: Kneesocks and her adopted sister Yui meet Selim Bradley, a "qwaser" who can control iron and is powered by breast milk. Their allies include Misa and her soma slave Satan, Naughty Nun Yuki, and Father Maki Ichinose. They have to protect a holy artifact from Evil Qwasers.
- Seitokai Yakuindomo: Yoshiyuki Sakurai recently enrolled in a new high school, Ousai Academy, because it was an easier commute. From the very first day he gets pressganged into the Student Council, which is chaired by Satan. Assisting her are a girl possessed by the Hell Girl and Karin Maaka, a genius returnee with an IQ of 180 who speaks fluent English and can do ten-digit calculations. All they ever do is talk about sex.
- Senki Zesshou Symphogear: Madoka Kaname gets drafted to fight Gnosis-like creature, alongside a broken Fate Testarossa, who didn't accept that Madoka got her powers from her beloved Dead Partner Nabiki Tendou. Their battles are observed by Itachi Uchiha.
- Senko No Night Raid: Allelujah Haptism, Ulquiorra Cifer and Van are one of the super-powered spies working for the Imperial Japan in 1930's Shanghai. Sanji is the long-lost brother of one of the spies and Allelujah's girlfriend is Saber.
- Shakugan no Shana: Ron Stoppable is walking in the street until he encounters Fiery Redhead Kagura fighting a demon by chance. After the fated encounter, Kagura decided to attend Ron's school to observe him. Eventually she falls for him and forms a Love Triangle with Ron's classmate Melfina.
- Shaman King: Nyarth is a ghost obssessed kid who befriends Lust, a Shaman who is engaged to Female Ranma. Together with Lust and his spirit companion Kamina, he goes on adventures with Edward Elric, Sanosuke Sagara and later Zorin Blitz.
- Shinkon Gattai Godannar!!: Phoenix Wright marries the MUCH younger Furukawa Nagisa and gets to fight a bunch of Giant Space Flea from Nowhere, assisted by a really busty Charlotte Aulin, and occasionally gets interrupted/helped with a duet of loli Signum and a gritty Tokugawa Ieyasu.
- Shugo Chara!: Mihoshi Akeno must battle The Heartless by using the powers of Yuno, Ahiru and Yui Hirasawa. She also has a crush on Graham Aker, but her rival Fate Testarossa won't let her have a word about that.
- Shukufuku no Campanella: Takumi Tsuzuki is a member of an adventurer's clan with Komoe. Solva and Miyako join him on the night of a meteor show when Mimi Usa wakes up.
- Silent Möbius: Dorothy Catalonia, a sorceress of no small power, joins an all female police force consisting of cyborg Bulma, Miko Marie Mjolnir, esper Orihime Soletta and hacker Shizuru, all of whom are under the command of "Hot Ice" Hilda in order to fight a race of extradimensional monsters.
- Sket Dance: Brief, Hayate Ayasaki, and Kyon create another club to help out others.
- Skip Beat!: Yoko is so in love with her childhood friend Setsuna, but when he became a celebrity, he dumps Yoko. With her feelings hurt, Yoko decided to become a celebrity that is bigger than Setsuna and joins the same talent agency of the country's biggest star and Setsuna's rival Tooya.
- Slam Dunk: Trunks joins his school's basketball club to impress Yukari Tanizaki, but she has her eyes on another member of the team: Li Xingke. Tessai, The Captain of the team, turns out to be Yukari's older brother, and he doesn't like Trunks that much. Other members of the team include vice captain Otacon, point guard Jinpei and returning legendary junior high player Dark Mousse.
- Slayers: Sorceress Canal Vorfeed and swordsman Folka Albark team up for food and treasure. They are later joined by chimera Kyouya Takamachi and Princess Shou Marufuji. White Priestess Urd and Golden Dragon Sango once traveled with the group. Of course, they are all being manipulated by a mysterious demon priest known as Gaara of the Sand.
- Softenni: Sanae Nagatsuki, Shinra Kuonji, Yui, Haruna Sairenji and Sari Sumdac are a mostly incompetent middle school tennis team.
- Heaven's Lost Property: Local pervert Kira Yamato finds a mysterious girl named Saki Morimi, who she sees as her master. At times, Kira will transform into his female counterpart Hatsune Miku in order to do more perverted things.
- Soul Eater: Jun and her human/weapon partner, Roxas, battle against villians like the evil witch Kagura, and her insane daughter/son, Mari Illustrious, with the aid of their friends, the cat witch Kagami, Ling, and Sarah. Also, Mu La Flaga is a jerkass Infinity+1 Sword.
- Special A: Mikuru Asahina is very obsessed with beating her childhood rival Lelouche vi Britania.
- Spice and Wolf: The Onion Knight is a traveling merchant who comes across Mai Shiranui one day. Together, they face the consuming evil of...economics.
- Spider Riders: Syaoran Li discovers another world, teams up with Leopolde Scorpse the spider and fights alongside Nina Einstein, Kururu, Hiyori Tamura & Meg against the forces of Warrior Volk, Douglas Rosenberg, Motoko Aoyama, Garlic Jr and Duo Maxwell.
- Strawberry Marshmallow: Ise Nanao unwillingly plays host to the antics of her plain younger sister Natsuki Kuga, and her friends Rukia Kuchiki, Angol Mois, and Natsuki Mogi, a Cute Clumsy Girl in glasses.
- Strike Witches: Kurumu Kurono is recruited by Natsuki Kuga and Lacus Clyne to join a group of female pilots who fight aliens with powerful jet engines strapped to their legs...but never wear pants.
- Suite Precure: Frequently fighting friends Kallen and Rukia become Magical Girls tasked with helping Excel collect musical notes before Dawn can steal them.
- The Great Mission to Save Princess Peach Tuxedo Mask falls in love with Toaster, who is captured by Marge Simpson. Finally, when Tuxedo Mask and his brother Wakko do save her, it turns out that Toaster is engaged to Kyanchome.
- Suzumiya Haruhi No Yuutsu: Chiko forces Raidou Kuzunoha to join her club. Chiaki, Kaede and Sebastian Michaellis also join.
- Tantei Opera Milky Holmes: Pinkie Pie, Applejack, Rarity and Rainbow Dash are a group of super-powered detectives who lose their powers at the beginning and go through various hijinks to get them back.
- Tekkaman Blade: Kyosuke Nanbu becomes an armored warrior-monster who'd invade Earth, but turns out to be rebelling and helps out the Earthling led by Bright Noah and assisted with Gourry Gabriev and Faye Valentine (he fell in love with Faye), reunite with his little sister Excellen Browning, only to see her die in front of him and must fight his evil little brother Shu Shirakawa and big brother Stern Neue Regisseur, who spearheaded the monsters attacking humanity.
- Tenchi Muyo!: Keiichi Morisato is told by his grandfather Dr. Wily of a demon in a cave. Driven nuts by it, he enters it and accidentally awakens Quatre. Her awakening catches the attention of Hatsuho Kazami, who is brought to Earth with her sister Sakura Shinguji. Quatre's ship Omochao is reborn just in time for Excellen Browning to arrive. Soon, Anaval Gato arrives, looking to claim a lot of power, only for Keiichi to defeat him and rescue Nico Robin with his newfound powers.
- Tengen Toppa Gurren Lagann: Jin Kisaragi and his best friend America both pilot a giant robot and, with the help of Senou Natsuru, battle an army led by Link. He also falls in love with Marikawa Shizuka.
- Tenjho Tenge: Kira Yamato and Kojiro are two new students at Todo Academy. They join the Juken Club, a fighting club consisting of Ami Mizuno, her younger sister Yuki Nagato, and Domon Kasshu, who has a crush on Yuki.
- Tiger & Bunny: Aging superhero Laguna Loire is forced to team up with a younger superhero, Claire Stanfield. Some of the other superheroes are Seto Kaiba, Stocking, Tsumugi Kotobuki, Accelerator, and Genichirou Sanada.
- To Love-Ru: Liz Thompson is an ordinary high school girl who accidentally molests alien Nagi in her bathroom. Fanservice ensues. In the sequel series, assassin Oshawott and Nagi's sister Yui Hirasawa are given more time in the spotlight.
- Toradora!: The romantic journeys of the tough-looking but actually gentle Black Knight and the pint-sized, initially angry Sabato. Multi and Yatterman-1 also compete for the Black Knight's feelings.
- Toriko: Proto Man is a food bounty hunter who wishes to create the ultimate meal. Edward Elric is his traveling partner.
- Transformers Generation One Anime:
- Transformers Headmasters: During their war, Dan Dastun and Hazanko encounter Captain Ginyu, Oolong, Devilman, Detective Tokuno, The Fallen, Speed Racer & Jonathan Washington. After Dan dies, Koji Kabuto assumes leadership (akin to the 1986 movie). Zoisite and Ru Shako (who also narrates) both fight each other, die and get rebuilt. Captain Planet also dies (at the hands of Jonathan, no less).
- Transformers Super God Masterforce: A group of robots consisting of Garma Zabi, Chap Adel, Man Wolf & Zensou Saeki recruit Sara Yuki, Urd, Chaozu, Rowen, Harry MacDougall, Toru Shirai, Detective Shiratori and Kougaiji against the war between Baron Ashura's male side, Slash / Michiru, Jinpei the Swallow, his brother Nigel Kirkland, Badass idiots Robin Mask, Buffaloman & Detective Gobugari and rookies Mondo Agake, Captain Tsubasa and Aphrodite.
- Transformers Victory: Captain Falcon leads his team of Alpha Bate, Dilgear, Astonaige Medoz, Siegfried Kircheis, Tony Frost; mini-bots Kei, Sailor Mercury & Apoline and his adopted son (yes you read that right), in the war against Roy Campbell and his forces.
- Transformers: Robots in Disguise: Terry Bogard, alongside his spiteful brother Mobead, Joe Suihan, Goki Muto, Speedbreakernote , construction vehicles May, Kuroro Lucifer, Dreadwing and Shoji Endo and bullet trains Tomoyoshi Ishizuka, Eiji Mishima & Raven, together with Shiho Nagaoka and Kisaragi Ninomai. Fights Akunamukanon and his minions Ikkyu the poet, bumbling idiots DJ, Starscream & Emporio Ivankov, sub-commander Rock Bison and military vehicles Aritomo Yamagata, Denny Brosh, Go Saruwatari, Kyoji Kawato & Step Johnny, who combine to form Bobby Max.
- Transformers Armada: Autobots Clank, Recca Hanabishi and Zartan travel across the Earth to find tiny, human-sized robots before Gateau Mocha, Jin Kazama, Prowl and Nagira. Along the way, the 'bots are joined in their search by fellow team members Bakunetsumaru, Hannes, Tsukasa Sekoguchi, Darkseid and Hayao Ichimonji and children Rikichi, Kate Ashley, Sachiyo Matsumoto, Kariya Mato and Taro Beppu. While Vincent Law, Robert Epps, Suzaku Kururugi and former Autobot Kondou Isao join the Decepticons. Towards the end, Mr. Clark becomes a threat.
- Transformers Energon: After the defeat of River Zastory. Autobots Kamina, Gai Shishio, Jinbu, Basara Nekki and Kaneda, together with reformed Decepticons Parn and Renzo Shima and humans Dave the Barbarian & Yosuke now face the Terrorcons and their leader Tarantulas. But before long, Akitoshi Okazaki is revived, takes back Parn and Renzo, gives them, the ghost of Quickstrike and Ramon Zero new bodies, steals Etemon from Tarantulas, adds Nightscream and his younger brother Ryou Takatsuki to his ranks and tries to bring River back to life. The 'Bots meanwhile, encounter and recruit commander Akio Furukawa, rookie Hayato Minagami, Thor, Douglas Rosenberg, former security guard Lau, Johnny Beppu, Lloyd Irving and Sinistra.
- Transformers Cybertron: Goliath and his team of Autobots - Kazuya Tanaka, Dr. Thunderland Jr., Yuusuke Saitou, Sideswipe, George O'Malley, Boichiro Yamato and Spike Witwicky, with humans Hirokazu Shiota, Miriam, Souseiseki, Motoko Mihara and Seiichi Suzuki, battle Michael Heartland, Darcia and Hachirota Hoshino for four "Planet Keys" that are needed to restore Inspector Gadget back to life. During the quest, Hikaru Ichibanboshi, Nakano, Miki, Benny, Parnell Jesek, Kirk Hamill, Francis, Hades, Shieldsaurus and Goddard align themselves with the Autobots. While Masami Hirukawa, his buddy Captain Jack Sparrow, Kikori, Sid Barett, Someoka Ryuugo, Yue Ayase, Count Balsamico, Red Star and Noboru Yamaguchi side with the Decepticons. Both Akuma and General Godwin end up changing sides at different points in the series.
- Transformers Go: Two teams of robots (one consisting of Moid, Andy W Hole and Golem, the other with Billy Peltzer, Youhei Sunohara and Itaru Shiodome) with the help of Ichika and Marika Kato, do battle against the recently reawakened Bravoman, Bighorn, Cyclops and Dallas Genoard to stop them from reviving their master.
- Trigun: France roams the land for his brother Yoshiyuki Terada. He is followed by Bulma, Kagome Higurashi, and Sousuke Aizen.
- Tsubasa Reservoir Chronicle: Vanitas travels with Lu Bu, Lucario, and Arika Yumemiya to regain Yusa's memories.
- Vampire Knight: Naru Narusegawa and Light Yagami are students whose duty is to keep the Day Class from finding out that the Night Class is composed of Vampires such as Tsukune Aono,Lelouch Lamperouge and Ayaka Yukihiro. Eventually Naru realizes that she is a vampire herself.
- Vampire Princess Miyu: (OAV): Chi-Chi is a vampire girl who, alongside her servant Aries Mu, must hunt down a race of demons. She crosses paths with spiritualist Balalaika.
- Vandread: Life really does stink for Solf J. Kimble. His co-workers Sôsuke Sagara and Tezuk constantly tease Kimble. Dipper is Kimble's robotic friend.
- Wedding Peach: Clumsy Rabi~En~Rose, well-mannered Cure White, and tomboyish June are Love Angels with the mission to destroy senders of hate, such as the Devil World's queen, Daisy Duck, Igamon, and Sailor Moon (Who later becomes good). Yuki-Sensei joins the team later on, and Tommy Pickles was a former devil who's now on the Angels' side.
- Weiß Kreuz: Zechs Marquise, Lockon Stratos, Dommon Kashuu and Clotho Buer are assassins with dark and troubled pasts.
- WORKING!!: The Hero is recruited by a petite Nyarlathotep to work as a waiter in the family restaurant Wagnaria, where he faces a diverse group of colleagues, including androphobic Feng Lan, katana-wielding Ami Kawashima, ex-delinquent manager Sergeant Keroro, stoic chef Hosaka, his fellow chef Nozomu Itoshiki and later Jin the Taxi Driver, who brought along with him Kyou Fujibayashi.
- The World God Only Knows: Takuma Higuchi is a Dating Sim God who makes a deal with the devil to capture runaway spirits with Eris.
- X1999(TV version): Shinn Asuka returns to Tokyo and must decide the fate of the world whether he should save it or destroy it. His childhood friends, Enma Ai and Archer, got involved in this situation.
- X-Men: After the 5th Mizukage dies (again), Michael Seebach rounds up all of his mutant students, which include Naraku, Shinigami-sama, Sailor Mercury, and Otacon, to go to Japan to find Rika Furude.
- ×××HOLiC: Lelouch stumbles in a mysterious shop owned by Beatrice who can grant wishes unless there's a price.
- Yes! Precure 5: Renton Thurston gets distracted by a butterfly and bumps into Trunks. He then uses the power of dreams to turn into a Magical Girl. With his best friend Takuya, Anarchy Stocking, Honey Kisaragi, and Mimi, Renton is tasked with collecting 55 pixie creatures in order to restore Trunks, Triela, and Tstutomu's homeworld.
- Yoroiden Samurai Troopers: Trunks, Might Gaine, Mello, Crusher Joe and Corkus don samurai armor to save the world from Dahal Muhammad and his henchmen 777 (who later does a Heel Faceturn), Ohtaki,  & a brainwashed Sailor Neptune.
- You're Under Arrest!: Bloodberry & Princess Kakyuu are a police duo in a force that also includes Gossip Girl Ryo-Ohki, Gentle Giant King Nikochan, a transgendered Jim Hawking, Princess Kakyuu's love intrest Gilgamesh and chief Soundblaster.
- Yu-Gi-Oh!: Sailor Uranus, a former pharaoh of Egypt, is reincarnated in the body of Shinji Ikari, who solved her puzzle. Together with Shinji's friends The Fourth Hokage (or Japan or Squalo), Yuffie Kisaragi, and Shinji's rival Marth (or 25-year-old Lambo/Spanner), they play children's card games. The Fourth Hokage has a romantic subplot with Gaz. All of the good guys join forces to ultimately take down villains like Ken and Chiro.
- Yu-Gi-Oh! GX: The hero of this story (who eventually becomes Dino) goes to a special school on an island. His rival is Spongebob Squarepants, who has a crush on Nana. His teacher is Ranma Saotome.
- Yu-Gi-Oh! 5D's: Lambo and Dino's old singing buddy is living in the derelict ruins of the previous series' city, and has created his own motorcycle to hunt down is old friend Vahn (whose Dann of Thursday turned into a giant Donut) because he stole something from him. Later on he meets up with two of his old friends, a director for a live action Black Butler, and a shogun from Gintama.
- YuYu Hakusho: Johan Liebert, Kefka, Pallazo, Shinji Ikari and Guy Shishioh are hired (conscripted) by Monkey D. Luffy to bust some yokai ass.
- Zettai Karen Children: Haruhi, Arashi, and Lala are a super powered fighting team led by Iceman Hotty, trying to stop an evil organization led by Urataros.
- Zoids: Chaotic Century: GyroMan discovers a pair of capsules which contain SharkMan and Kirby. They soon run into Axel and Klonoa who soon join them to stop the evil plans of Chibodee Crocket. Soon enough Gyro Man encounters a mysterious rival known only as Tsukasa.