- Team America: World Police: Gary stars in a parody of RENT called "LEASE", which exaggerates the HIV/AIDS aspect of the musical ("Everyone has AIDS").
- Hedwig and the Angry Inch has Yitzak leaving the company because he's offered the part of Angel in the Polynesian tour of RENT. This Shout-Out happened because John Cameron Mitchell was offered the same part, but he turned it down because of Hedwig.
- Incest! The Musical: Jenny tells Alex that the PTA is boycotting the theater department's production of RENT because of it's depiction of non-normative sexual relationships.
- The Lonely Island mentions the musical in the song "No Homo".
Ey yo, I kinda like the musical RENT (no homo)
Live Action TV
- The Big Bang Theory: Penny is an aspiring actress. In one episode, she gets a gig as a stand-in of Mimi in a production of Rent. It's off-screen. The episode dealt with Sheldon's escalating lie when the guys invented a cousin who is a drug addict.
- Broad City: Lincoln casually wonders why the hell the characters would think they didn't have to pay rent.
- Supernatural: Dean quoting RENTas an inspirational speech for a play in an episode.
- In one of his last few episodes of The Office (US), Michael's coworkers sing "Seasons of Love" to him after a disastrous award party.
- The Simpsons: In "Behind the Laughter", Homer mentions that while The Simpsons went on hiatus, he acted in a sequel to RENT, where he played a Dastardly Whiplash landlord called Mr. Stingely.
Homer: I literally chewed the scenery.