Marge goes too far in cleaning the house and passes out after inhaling too many cleaning solvent fumes. When she wakes up in the hospital, she has amnesia, which is seemingly cured when she recognizes herself and her children through her quirks, but doesn't remember Homer at all.
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* CallBack: Homer punching UsefulNotes/GeorgeHWBush in [[Recap/TheSimpsonsS7E13TwoBadNeighbors Two Bad Neighbors]]
* ComicallyMissingThePoint: Marge desperately cleans her home to keep a cleaning lady from seeing how dirty her family is.
* ImagineSpot: Marge has one with cleaning ladies gossiping about her family.
* NoodleIncident: Homer punching [[UsefulNotes/GeorgeWBush George Bush, Jr.]]
* WholePlotReference: To the film ''Regarding Henry''.