In the first episode of the series after being UnCanceled for good, Lois and Peter take a trip to rekindle their waning romance -- and end up on the run from Mel Gibson, who is plotting to make a sequel to his controversial religious movie, ''Passion of the Christ''. Meanwhile, Brian and Stewie are put in charge of disciplining Meg and Chris.
!!"North By North Quahog" contains examples of:
* DisneyVillainDeath: Mel Gibson.
* EpicFail: Peter apparently once forgot how to ''sit down''.
* FreudianSlip: When Brian meets with Tom Tucker about Jake, his upside down faced son, giving Chris alcohol at school:
--> '''Brian''': This whole situation has just turned his whole life upside-down face.\\
''(Stewie slowly turns and glares at Brian)''
* LongList: The ColdOpen shows Peter sadly telling the rest of the family that their show has been canceled to make room for more important shows, proceeding to list several short-lived Fox shows which had come and went since ''Family Guy'' had gone out of production, including ''Series/That80sShow''[[note]]though that show would more or less live on as ''Series/ItsAlwaysSunnyInPhiladelphia'', as Glenn Howerton, Charlie Day, and the actress who plays Corey's bisexual ex-girlfriend would be on that show[[/note]], ''Series/ThePitts'', ''Cedric the Entertainer Presents'', ''Series/{{Titus}}'', ''Series/{{Undeclared}}'', ''Series/{{Firefly}}'', ''Series/DarkAngel'', ''Series/GregTheBunny'', ''Series/TheTick2001'', ''Wanda At Large'', ''Andy Richter Controls The Universe'' and ''Series/{{Action}}''. He concludes that their show only has a chance to come back in the unlikely event that ''[[{{Irony}} all]]'' [[{{Irony}} of these shows go down the tubes]].
* TakeThat: When Meg asks Chris to turn the channel to ''Series/TheGeorgeLopezShow'', Chris says the show perpetuates the stereotype that George Lopez is funny.
* WasTooHardOnHim: Stewie asks Brian this when he spanks Chris after catching him with vodka, despite that Chris was framed by a student.
-->'''Stewie''': Do you think we were too hard on Chris tonight?\\
'''Brian''': What? Oh, God. No, no. I don't...I don't think so. Do you?\\
'''Stewie''': Oh, no, I just always feel badly when we have to be strict.
* WholePlotReference: The episode's A plot is one to ''Film/NorthByNorthwest'', including the famous crop-duster chase and showdown at Mount Rushmore.