Laser-Guided Karma: Peter suffers this when Brian shaves off his fur, and gives Peter a taste of his own medicine.
Major Injury Underreaction: Peter taunts Brian by mailing his penis, collapses after losing too much blood, which he didn't pay attention to.
Off Model: Brian is arguably this after he shaves himself. He's been shown without fur during the episode where the family goes swimming in a toxic lake (as well as a cutaway gag) and is drawn differently. More likely Played for Drama, however.
The Pig Pen: Peter, as shown in the cutaway scene when he doesn't shower for six months.
Please Put Some Clothes On: Brian to Peter throughout the episode, and Stewie to Brian in the final scene after Brian shaves himself.
Slow No: Meg at the cafeteria when bumping into Mike.
Truth in Television: The uncaring administration when Meg complains that Mike has threatened her personal safety is, sadly, a real-life occurrence in too many junior high and senior high schools in America.note (Explanations vary; everything from poor to no training to combat bullying, to "boys will be boys" to outright support for the bully by administrators.) There is also the fact that Meg's friends deserted her because they could "be targeted for association" and the fact that, when Quagmire was being bullied, his classmates did nothing, both of which also occurs in real cases of bullying.
Ungrateful Bastard: Brian thanks Stewie for suggesting he shave himself, to which Stewie simply snarks that he can't believe Brian went through with it, even though Stewie was clearly serious when he suggested it to Brian!
With Friends Like These...: Meg's friends (the nerdy girls who sometimes hang out with her, despite many jokes and references to Meg not having any friends at all) refuse to help Meg in her hour of need.