A high end courier is found murdered with the only witness a woman with an unusually strong sense of smell.
- Cain and Abel: The victim, Justin, was murdered by his brother Graham because he found out that Justin wanted to give away the real Van Gogh instead of selling it and splitting the proceeds, which Graham needed to pay off his gambling debts.
- Fingore: Castle smashes the fingers of one of the suspects with the trunk lid of his own car.
- My Sensors Indicate You Want to Tap That: Mia could smell Beckett's pheromone levels increasing around Castle, which she informs him of.
- Nasal Trauma: While defending himself from the painting's original owner, Castle accidentally breaks Mia's nose.
- Shot in the Ass: While chasing a suspect, Ryan accidentally shoots Esposito in the ass, forcing him to use a cane for the rest of the episode.
- The Nose Knows: The witness who called in the murder, Mia, is a woman with hyperosmia, so her nose is highly sensitive to odors. Among other things, she could smell that the painting that the precinct recovered was a forgery.
