Asok: You are dressed very odd.
Phil: It's casual day.
Asok: That's the most frightening outfit I have ever seen.
Phil: You haven't seen me in bicycle pants.
"Find anything interesting?"
— Barry Burton, completely ignoring the decomposing snake that Jill Valentine just killed, Resident Evil
"On any other day, that might seem strange."
— Cameron Poe, ignoring a car being towed behind the plane by a rope as he hunts escaped convicts, Con Air
River Song: How could we miss that?
The Doctor: Low level perception filter, or maybe we're thick.
"Asides from the wounded soldier lying unconscious, starving, and dehydrated in the main hallway, the remainder of the summer remains uneventful."
Dr. Venture: Okay, Hank, you're taking this way too well.
Hank: Well gee, dad, we've seen a lot of strange stuff over the years. Last week, we were fighting a giant dinosaur.
Dr. Venture: Granted, but I wasn't the dinosaur. Can't you see where maybe this is different?
— The Venture Bros., after Dr. Venture is turned into a giant caterpillar, "Mid-Life Chrysalis"
"Mm-hm. Mm-hm. Pretty neat."
"You just saw this guy flying! Be impressed, dammit!"
— Linkara on Captain Electron
C-Sec officer: A few minor changes were made to reduce the risk of geth infiltration. We apologize for the inconvenience.
Legion (a geth): Geth do not infiltrate.
C-Sec officer: You should leave your personal synthetic assistant at home. They're not allowed on public shuttles any more.
Legion: (sidelong glance at Shepard) Geth do not intentionally infiltrate.
"She's just being Pinkie Pie."
—Several different characters from My Little Pony: Friendship is Magic
"Kid, you're on a raft with fucking DINOSAURS! How about a little acknowledgement of this miracle, huh?"
Grishnak: You're a strange lookin' group. What'dya want?
Knight-Captain: ... says the half-orc pirate.
Howard: Nice place. You pay to live here?
Beverly: It's cheap, the manager of my band found it for me.
Howard: I suggest you find a new manager.
Beverly: Hey, I'd love to, but we got this damn contract with the sleazoid. He won't even give us the money he owes us.
Nostalgia Critic: YOU KNOW YOU'RE TALKING TO A DUCK, RIGHT?!