Chakravartin: You have exceeded my expectations. I praise you. You are indeed the one to inherit this world. Gaea must be led by one of its own. Now that you have become a perfect being, I may now leave this world, and save other worlds in need of my guidance. Come, and join your daughter (...) (extends hand) I am counting on you.
Loki: ENOUGH! You are, all of you, beneath me! I am a god, you dull creature, and I will not be bullied by-
The Incredible Hulk: ...puny god.
Condiment King: "What's this? Ah, the Big Bad Bat Guy. I knew you'd ketchup to me sooner or later. How I've relished this meeting. You, the Dynamic Dark Knight, versus me, the Conceptual Condiment King! Come, Batman, let's see if you can cut the mustard.
Batman: *delivers a single punch to CK's stomach* Quiet!
Fritz Stanford: HAHAHAHAHA! Are you afraid?! There's no way you're not! Now witness the awesome power of —
Revy: Shut the fuck up. Can't you see I wasn't even listening? I mean, were you trying to sell me the damn gun or what?
Hari: And you don't block a groin-kick with your hands, you take it on the thigh. Every time you drop your hands, you're gonna get a whack. You understand?
Kris: Yes, I'm starting to— (takes uppercut to solar plexus)
Hari: Lesson two. Best time to hit someone is when he's off guard. Best time to catch someone off guard is when he's talking. When you talk, you're thinking about what to say next, not— (takes jab to face) ... Y'know, there's just the faintest chance I could start to like you.
Don't speak. Just die.
— Dante, Devil May Cry 2
When you have to shoot, shoot. Don't talk.
— Tuco, The Good, the Bad and the Ugly
Psycho Mantis: Hold up... Crash Bandicoot? SERIOUSLY? You played THAT!?
Solid Snake: *shoots Psycho Mantis on the head*
I've had enough of your snide insinuations!
Commander Shepard, Mass Effect 1
I've had enough of your disingenuous assertions!
Commander Shepard, Mass Effect 2
Some people think they can outsmart me. Maybe... Maybe. I've yet to meet one that could outsmart boolit.
— The Heavy Weapons Guy, Team Fortress 2
Let this be a lesson, kids. When debating, solve your problems not with an agreement, but by screaming "I AM A MAN!" and punching them in the guts. Allow me to demonstrate. "I AM A MAN!!!" *punch*
Megatron: Oh well, come on, let's have it. The usual "destiny and honor" speech.
AK-130 Android: Intruder. Identify yourself.
Rubber Soul!Kakyoin: I'm Rubber Soul!
(Rubber Soul reveals himself.)
Rubber Soul: And this is my real identity, Rubber Soul, Mr. Damn Handsome.
Jotaro: What's with this guy? He's annoying.
Rubber Soul: Huh? What was that? There's something on my face? What is it? Huh? Handsome? Hehaha! Handsome on my face. Huhuhuhu! Seriously?! Oh man! Hahaha, Handsome on it, oh man! Can wash that off. Nah, no way, it's Handsome after a...
(Star Platinum decks Rubber Soul in the face.)
Jotaro: You're pretty damn irritating!
(Star Platinum pummels Rubber Soul some more.)
"The law of my fist is about to compel your teeth!"
— The Blackfish, Game of Thrones
Judge Fear: Gaze into the face of Fear!
Judge Dredd: GAZE INTO THE FIST OF DREDD!
(Dredd puts his fist through Judge Fear's face and into his skull up to Dredd's wrist.)