McBain: But, captain, I can't avenge my partner's death with the pea shooter.
Captain: I don't wanna hear it, McBain – tha-that cannon of yours is against regulations! In this department, we go by the book.
[McBain fires part of the book through the wall]
McBain: Bye, book.
"Why the fuck didn't you tell us there was someone in the bathroom? Slip your mind? Did you forget that there was someone in there with a goddamn hand cannon?"
— Vince, Pulp Fiction
"I know what you're thinking, punk. You're thinkin', 'Did he fire six shots or only five?' Now, to tell you the truth, I forgot myself in all this excitement. But being as this is a .44 Magnum, the most powerful handgun in the world, and will blow your head clean off, you've gotta ask yourself a question: 'Do I feel lucky?' Well, do ya, punk?!"
— Inspector Harry Callahan, Dirty Harry
"Putting it down your pants compensates not only for your own penis, but for every penis within a twenty five mile radius."
— Ben Thompson, talking about the S&W .500 Magnum.
"Stranger! (laughs) What do you need that for? Goin' hunting an elephant?"
— The Merchant, Resident Evil 4, on purchasing the Handcannon
"WHY DOES THAT HOWITZER HAVE A HANDLE AND FUCKING TRIGGER!?!"
""Monster of the East", huh? Well, I've got the Monster of the West right here in my holster. Hope I get to introduce them."
— NCR Ranger chatter, Fallout: New Vegas
"The Five Hundred Magnum from our mutual friends at Smith and Wesson. Makes the gun of Dirty Harry look like a weasel's cock. Enough to stop even the largest charging buck."
— Leopoldo Luna, The Punisher Presents Barracuda
"Shirou's gun was clearly not a toy, but an honest-to-goodness, Israel-made Desert Eagle .50 AE - often called a "hand cannon" and no doubt the strongest handgun in the world."