"The Firstborn, children of a lifeless universe, cherished life above all else. It was as if they saw the universe as a park, and themselves as gamekeepers charged with its preservation. But gamekeepers must sometimes cull."
Your civilization is based on the technology of the mass relays, our technology. By using it, your society develops along the paths we desire. We impose order on the chaos of organic evolution. You exist because we allow it, and you will end because we demand it.
"Human, you've changed nothing. Your species has the attention of those infinitely your greater. That which you know as 'Reapers' are your salvation through destruction."
"Shepard, you have become an annoyance. You fight against inevitability. Dust struggling against cosmic winds. This seems a victory to you. A star system sacrificed. But even now, your greatest civilizations are doomed to fall. Your leaders will beg to serve us. Know this as you die in vain, your time will come, your species will fall. Prepare yourselves, for the arrival!
Your kind feared the darkness, so we gave you light. You begged us for the Purge, and did it not come to pass? Now you spurn our counsel? You must learn your place!
We now know that the Decepticons are not our only foes, that another more dangerous race of beings also plan our destruction. Our universe will never be the same again. We Transformers have looked into the face of our creators and seen the face of an enemy.