Cheryl is a serial homewrecker who enjoys destroying families by seducing and sleeping with married men so she can tell everything to their wives and kids afterwards. Points added if she has no Freudian Excuse.
Cheryl has sex and is praised for becoming a "real woman".
Gender Flipped: Bob learns the hard way that having sex with women does not made him a stud.
Cheryl is being called names for having had sex but it turns out she didn't and everyone involved in the bashing is sued for public slander.
Cheryl is a Good Bad Girl who likes to see herself as an Ethical Slut and, even though she gets called names, she leads her life regardless of what people may say.
Double Subverted: After the hoopla over insulting Cheryl is over, she reveals to her best friends that she only gives handjobs and blowjobs. Thus, her hymen is intact!
Parodied: Shaming the Slut is a yearly parade, where someone wears a ridiculous costume based loosely on a cheerleader's uniform and they pelt it with water balloons.
Zig Zagged: The town gets in an uproar whenever side characters have sex, but the heroine is allowed to get away scot free and is even given free muffins for life at the bakery for losing her virginity, until a monster shows up and the town decides to sacrifice her to it for being a giant slut, only it turns out the monster only eats virgins as a punishment for not having the emotional maturity to just do it.