Josephine robs a bank. The police show up to arrest her, but take one look at her and immediately start fighting amongst themselves over who gets to help carry her dollar-sign bags to the getaway car. The sole female officer of the group is less than amused and speaks out in protest, only to be shushed by her male coworkers and threatened to be reported to Da Chief if she keeps "interfering with the investigation".
Josephine's beauty attracts more attention to her, and thus more scrutiny to her unscrupulous actions.
Plain Jane is assumed guiltless, because people think manipulation relies on looks. Cue Wounded Gazelle Gambit.
Ivan uses his intimidating appearance to intimidate people into cooperating with him without having to resort to overt threats.
Josephine gets blamed for something she didn't do because she's ugly.
Alternatively, people are jealous of her looks and punish her far worse than they would an average-looking person.
Or People are jealous of her looks. So they compensate by assuming she's a bad person even though she's actually is a really polite Ideal Hero or more realistically a really polite Classical Anti-Hero.
Josephine attempts to use her looks to manipulate others; unfortunately, the people she tries to manipulate don't actually find her attractive.
Josephine gets away because the people are insanely forgiving, not for her looks
Double Subverted: The reason it didn't work on the last man whom Josephine used her looks on was because he was gay; as soon as she finds a straight man, she's got him wrapped around her little finger.
Parodied: Josephine is the very definition of Gonk, yet it still works thanks to an Uncanny Valley Make Up that makes her look even MORE repulsive for the audience, but irresistible to the in-universe characters.
Zig Zagged: Josephine gets called on her manipulative behavior by boyfriend Bob, but she lavishes him with a little extra affection until he's putty in her hands, willing to do anything for her. She then sets Bob and Dave against each other for laughs; this leads to Bob's death and Dave being seriously injured and Josephine's Heel Realization... only she doesn't care. Not until Bob's sister Maybelle comes after her and scars her face, robbing her of the very thing she used to avoid punishment for her misdeeds...
Averted: Josephine's looks don't factor into how her various crimes / flaws are dealt with.
Josephine's mom tries to teach her it's bad to manipulate people at young so that this trope won't happen.
Discussed: "She's cute. There are different standards for cute people". "You mean no standards".
Beauty is fleeting, so Josephine's sway over others naturally wanes with time. Eventually, she's forced to face the consequences of her actions without her pretty face to protect her.
Josephine's seductive abilities will be of no use to her this time because the ones out to get her are women and they're not lesbians.
Aware of this natural time-limit, Josephine nevertheless decides to flaunt it while she's got it.
As her beauty slowly fades, she realizes she won't be able to get away with being a Jerk Ass any more and becomes a better person as a result. By the time she's completely lost her looks, she's a Cool Old Lady.
Played For Laughs: Josephine uses it as an actual legal defense for Hero Insurance despite use of nuclear weapons. The courts just accept it and release her immediately.