Justified: People get sick. And sometimes, especially in times or places where there isn't modern medicine (or where there is, but no cure is as yet available), people's lives can be cut short by the disease.
Inverted: Alice is physically healthy, but mentally ill.
Subverted: Alice is sick, but seems to be on the mend.
Alternatively, Alice's illness is mostly a mental one, but has a physical component that really takes a toll on her.
Alice's illness isn't all that serious.
Double Subverted: Just when it seems to have cleared up, the Soap Opera Disease comes back with a vengeance, and this time, medicine cannot cure Alice. Cue A Death in the Limelight.
Reconstructed: Alice's reflection helps her come to terms with her illness (and her mortality). She might even befriend someone who helps make her last days meaningful.
Zig Zagged: Sometimes, Alice has "good days" where she feels relatively better, can get out of bed, etc. Other days are "bad days" where Alice feels lousy and lacks energy.
Averted: Alice is perfectly healthy.
Enforced: A Shout Out to romantic literature (such as that by Edgar Allan Poe), or the writer wants to explore themes of sickness, death, and dying.
Defied: Alice is very sick, maybe even terminally so, but she refuses to stay in bed contemplating the last leaf on the tree outside. Instead, she goes out and makes the most of the time she has.
Alice is very sick, but it doesn't stop her from being a BadassAction Girl. Or really anything else.
Discussed: "Alice doesn't have much longer..."
Conversed: "It's totally cute to be weak and helpless—as long as she doesn't actually die from whatever."
Played For Laughs: Alice fakes being seriously ill to get out of doing something she doesn't want to do.
Alice makes a big fuss out of a common cold.
Played For Drama: The whole premise of this trope, when played straight.