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Occasionally, while performing surgery on the alien, one of the body parts will start making noises when you remove it. The fact that they move on their own makes it worse.
Eye transplants. Have fun ripping out the patient's eyes as they pop out before they become loose enough for you to tear off!
You can replace the eyes with an 8 ball and a ball with a smiley, making poor Bob perfectly blind.
Even if you're not doing eye surgery, Bob will occasionally have his eyes open if you shake his head around, and they're staring right at you. This is even more unsettling when the eyes are open and Bob dies.
The fact that Nigel is selling spare organs and Mystery Meat to his friend, who serves them as food at his diner, may add to the fuel. Poor guy doesn't know. Not that he cares.