Made all the worse by the fact that the Roboticizer was originally invented to help people who are dying of sickness, by converting the infected parts to metal. The inventor (Uncle Chuck) has to live with the knowledge that his invention has effectively condemned almost everyone on the planet to a Fate Worse than Death, himself included.
In the time travel episode, we get to see that Sonic actually stood in line right behind Uncle Chuck and watched him get roboticized... when he was like FIVE YEARS OLD. Jesus, that's harsh.
In Sonic's Nightmare, Sonic envisions Sally being put in the roboticizer while he watches helplessly.
Not to mention that quote from Sally..."Where were you when the brains were handed out?"
It's likely that was just Sally taking a jab at Sonic's stupidity. Said quote is an actual way of insulting someone in real life for their alleged lack of intelligence.
Tails nearly getting trampled by a Terapod herd in "Sonic Past Cool."
The robot double from "Sonic and Sally" could very well have been a roboticized Mobian.
The glowing red eyes against a black background in the finale.
The end of "Ultra Sonic" where Uncle Chuck reverts back into an automaton with no free will and starts snarling at his nephew like a rabid dog, prompting Bunnie to drag Sonic away. Again, keep in mind that while this is going on, Uncle Chuck's completely aware of it and yet can't do a thing.
Ben Hurst's original plans for Nicole: she used to be a child prodigy, and Sally's best friend; Robotnik takes notice of this and has his SWATbots bring her to him one day. He says that she's been selected to participate in a research project, but first he needs to give her some forms for her parents to sign. She agrees and follows him into a room with a machine that he asks if she will let him connect her to, to make sure it'll fit. He proceeds to transfer her consciousness to the computer said machine is hooked up to, killing her original body—that's right, Robotnik just straight-up murdered a child—and leaving Nicole, now an AI, trapped in her handheld. She realizes she's dead and that she'll have to work for Robotnik, and begins analyzing the potential results: strip every sentient being on Mobius of their free will, leaving her completely alone, or make everyone happy at the cost of also removing their free will. She instead suppresses her personality, mind-wipes Robotnik, and manipulates him into handing her over to King Max, who in turn entrusts her to Sally, who's unaware that the AI is all that remains of her best friend. One can only imagine what her parents were going through.