"You asked what about me? It's simple. I love cutting up live people, and I like killing people so much, I can't stand it. I kill; therefore I am! I am who I am. That's all the evidence I need!"Fullmetal Alchemist has several especially heinous villains.
—Barry the Chopper (anime version only), "The Red Glow" (subtitles)
Original manga and Brotherhood:
- Shou Tucker, the Sewing-Life Alchemist, is known for his ability to create chimeras capable of speech. He's introduced to the Elric brothers as an awkward Nice Guy with a 4-year-old daughter named Nina. With his State Alchemist license soon to expire, Tucker created another Chimera by fusing Nina and her dog Alexander into a miserable Half-Human Hybrid which is in constant agony. When the Elric brothers discovered Nina's new state, Edward's rage nearly drove him to kill Tucker. It is then revealed that the other speaking Chimera was actually his wife and Nina's mother, whom Tucker created by fusing her to another animal, earning him his State Alchemist status in the first place. Tucker refuses to admit what he did was horrible, going as far as to tell the Elric brothers that they shouldn't have a problem with his actions and that anybody else would have done the same thing For Science!. While only appearing in one chapter, Shou Tucker manages to be one of the most depraved characters in the manga and Brotherhood anime.
- The unnamed and utterly heinous Gold-Toothed Doctor crosses the Moral Event Horizon in one of Bradley's flashbacks, when he's shown cackling with glee as he puts one subject after another through the process intended to create Wrath; this process horrifically kills the first twelve candidates, deconstructing their bodies while they are still alive. In the present day he only gets a few scenes, but they are more than enough. He uses his medical alchemy to heal Mad Bomber Solf J. Kimblee so that he might be unleashed upon the heroes again. He later looses the remaining Fuhrer candidates (all of whom have been reduced to an essentially mindless state) on Ed, Roy, Hawkeye, and Scar to prevent them from interfering with Father's plans to destroy the country, activates the Transmutation Circle that sends Ed, Al, and Izumi into Father's presence, and finally has one of the candidates slit Riza Hawkeye's throat in an attempt at forcing Roy to perform human transmutation and open the Gate. Perhaps most importantly, he's privy to Father's endgame (unlike Central Command, who believe they are all going to receive immortality) and simply doesn't give a damn. No explanation for his actions is ever given, and he spends all of his appearances sporting a Slasher Smile and bragging about his achievements as a scientist.
- The Sacred Star of Milos: "Melvin Voyager", actually Security Chief Atlas, is a power-hungry, sociopathic Cretan soldier, who starts off by denouncing his vows to protect the Crichton family by brutally murdering the female protagonist Julia's parents and then rips the skin of Julia's brother's Ashleigh's face in order to steal his identity. This was done so that Atlas could easily manipulate the rebel group, Bats, into making a transmutation circle for him by promising Creta enough power to rival other nations. Ashleigh, in turn, ended up becoming a vengeful Knight Templar, seeking revenge for Milos after losing his faith for its people. After showing his true colors, Atlas murders Bats' leader, Miranda, so that he can use her blood to activate the circle. He then proceeds to murder his co-conspirator, Raul, as well when it turns out there is not enough sacrificial blood. After succeeding in activating the circle, Atlas sacrifices dozens of Amestrian soldiers by feeding them to Milos's machinery to create a Philosopher's Stone for himself. A textbook sociopath who abandoned his honor and home country for power, Atlas stood out as one of the most vile villains in the Brotherhood canon.
- Dante is a 400-year-old woman with a penchant for Body Surfing; she's stayed alive this long by jacking innocent people's bodies, ditching them when they start to rot, and repeating the process infinitely. When her own Philosopher's Stone runs out, she sets in motion a plan to cause so much misery in Amestris that someone will be desperate enough to recreate the Stone, allowing her to steal it with no risk to herself. She's abusive towards her Homunculi "children", arranges for Ed to kill Greed, jacks her own assistant's body, and finally, attempts to steal the body of one of the hero's Love Interests, who had already been severely traumatized by rape/pregnancy, solely so that she can force him to have sex with her. Said hero is both a teenager, and her ex-boyfriend's son. She later shatters the mind of one of her Homunculi servants when he dares to miss his dead friend, turning him into a mindless eating machine. She's never shown in a sympathetic light, comes off as an overconfident Jerk Ass in person, and doesn't even have the excuse of not being human to protect her.
- Envy lacks all the pitiful qualities that his manga counterpart had. An Ax-Crazy sadist, Envy uses his Shape Shifter Guilt Trip by taking on the forms of people's loved ones before killing them. He is the one responsible for murdering Maes Hughes, by impersonating his wife and rubbing it at his face before killing him. Envy is mostly seen manipulating Amestris's government behind the scenes with a string of mind games and murders, while Pride controls the military as King Bradley. This all culminates in him killing Ed when he finds out that Envy is in fact, the homunculus version of his half-sibling. Unlike other homunculi, who wanted to become humans, Envy was the sole exception, only working for Dante so he could kill as many people as possible, abusing both other homunculi and prisoners in the process simply for laughs. His Parental Abandonment as a Freudian Excuse doesn't even come close to justifying his homicidal mania and Envy completely undermines it in Conqueror of Shamballa when he decides to murder his father rather than trying to reconnect with him.
- King Bradley/Pride is the military dictator of Amestris and one of Dante's most trusted homunculi. He is the mastermind behind the events that caused the genocide in Ishbal, and worse yet, repeats the same actions in Reole in order to lead his own nation in destruction. At one point, he even releases infamous Mad Bomber Solf J. Kimblee from prison and unleashes him upon Reole citizens in order to take care of the deed as fast as possible. While mainly assisting Dante in her plans to create the Philosopher's Stone all over again, it is made clear that Bradley enjoys committing these deeds for the sake of "purifying" the population and expanding the country's territory. After Martel finds out about Bradley's true identity, he proceeds to murder her cold-bloodedly in front of Al in order to keep her silent. It is not until the final arc of the series when Bradley reaches the level of an irredeemable monster, when he plays a sadistic cat-and-mouse game with Roy Mustang, torturing him both physically and emotionally, even bringing up the tragic fact that he couldn't save his best friend from a certain death. When his own son steps in the hopes of helping his father, Bradley strangles him to death while ranting about being an agent of God.
- Solf J. Kimblee stands out as even more insane and psychotic than his manga counterpart. A state alchemist with the ability to turn objects—and people—- into explosives, Kimblee Loves the Sound of Screaming and earned a reputation during the Ishbal genocide for his ruthlessness. As seen in early flashbacks, Kimblee was responsible for massive explosions all around the region, all while laughing about it. He also tortured Scar by sadistically blasting him apart one piece at a time, making him the distinctive mark in his forehead. Later, Kimblee escapes the prison by using a fellow inmate as a bomb and starts working for Greed before betraying him to Frank Archer and being indirectly responsible for the Devil's Nest massacre. After his reinstatement, Kimblee reenacts the Ishbal genocide in Reole and tries to murder Al by transforming him into a walking time bomb. When encountered by Scar, Kimblee reveals that he has no reason for fighting, other than the fact that he sees humans—not exempting himself--as empty beings and that he simply enjoys seeing people suffer.
- Barry the Chopper, unlike his manga incarnation, is far more vicious and horrifying. Barry was once a simple butcher living in Central City who had grown bored with his life of cutting up pigs and cows. One day, to see what it felt like, Barry decided to chop up his wife and quickly found that he loved the sensation. What followed was a string of women being brutally murdered. Barry's killing spree came to a temporary halt when he was arrested after trying to kill the Elrics' childhood friend, Winry. Rather than be executed, Barry was experimented on, had his soul bound to a suit of armor, and became one of the guards for the Fifth Laboratory. After the lab's destruction, Barry slaked his bloodlust by joining a group of mercenaries to slaughter a camp of harmless Ishvalans. An utter sociopath, Barry killed people for no other reason than because he enjoyed it. When asked by Alphonse if Barry was afraid that he wasn't the real Barry and was just an artificially constructed soul, like Barry accused Alphonse of being, Barry stated that it didn't matter if he was the original Barry or not* . Barry claimed that so long as he had the ability to kill people, he loved who he was: "I kill therefore I am."