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"So come now... Children of Nibiru! Be strong, and set your master free, so that I may bathe this world...in fire!"

"There is only darkness for you, and only death for your people. These ancients are just the beginning. I will command a great and terrible army... and we will sail to a billion worlds. We will sail until every light has been extinguished. You are strong, child. But I am beyond strength. I am the end."
The Lich to Finn, Adventure Time, "Escape from the Citadel"

Cartoons have always been home to supervillains whose whole lives seemed to be dedicated to committing evil acts, without any redeeming qualities to speak of other than humor. And then there are some who took it even further. Much further.

Other non-Anime works can be found here, while Animated Films can be found here.

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  • Action Man (2000): Dr. X is the mastermind of all the evil in the series, committing all his crimes in the name of evolving humanity into perfection for him to control. X kicks the series by off by kidnapping, torturing, and bodyjacking the young athlete Brandon Caine, using his body to form the Council of Doom and carry out a variety of atrocities against humanity. Seeking to weed out the weak and useless parts of humankind and replace them with a "Neo-Humanity" of his own design, X unleashes lethal plagues, threatens nuclear and winter holocausts, and attempts to copy his mind into every human on the planet to reign supreme. X's supposedly well-intentioned goals are disproven time and time again with his sadism and egomania, before he finally snaps and drops all pretense of improving humanity to instead try to drag an asteroid down to Earth and wipe out all life on the planet — including his own Council of Doom — before creating a new race of humans in his own image.
  • The Adventures of Puss in Boots: The Bloodwolf is an ancient being of fear that existed before time itself begin, once attempted to destroy the entire world before being sealed away by a wizard named Sino in the Netherworld. Upon being released by Uli, the Bloodwolf shows no gratitude and tossed him aside while coldly stating that he'll destroy him and the whole town of San Lorenzo. The Bloodwolf later tortures the whole town with their greatest fear so that he could wait for the Blood Moon where he would reach his full power, so he could continue his quest to bring about the complete destruction of the world.
  • The Adventures of Tintin: R.J. Rastapopoulos is, much like his counterpart from the original comics, Tintin's most ruthless foe, and personal Arch-Enemy. Initially appearing to just be a benign film producer, Rastapopoulos is eventually outed as being the leader of a massive drug smuggling ring that is operating out of Africa and Asia. Anyone who opposes Rastapopoulos is either killed or driven insane by a special poison, and when Tintin begins dismantling his organization, Rastapopoulos tries to have him and his allies, the Wangs, beheaded by the Wangs' own poison-maddened son, Didi. Later, in attempt to rebuild his criminal empire after it was toppled by Tintin, Rastapopoulos draws up plans to steal the wealth of a millionaire named Laszlo Carreidas using a truth serum developed by his new ally, Doctor Krollspell. When he is accidentally injected with the serum, Rastapopoulos inadvertently lets slip that he was going to shoot Krollspell as soon as they finished with Carreidas. When this plan is foiled, Rastapopoulos, under a new identity, starts promising Arab refugees safe passage to America. After the refugees give him all of their valuables, Rastapopoulos has them drowned in the Pacific. When Tintin begins investigating his latest activities, Rastapopoulos tries to get rid of him by planting a bomb on a passenger airplane that Tintin had boarded, and by blowing up one of his own refugee-filled ships when it is taken over by Tintin.
  • Adventure Time: The seemingly sweet land of Ooo has many villains, but while many are either very tragic or not serious, the same cannot be said of the following:
    • The Lich is an evil, ancient sorcerer, the "last scholar of GOLB", and the series's defining Knight of Cerebus who returns time and time again from seeming destruction focused solely on one thing: the destruction of all life.
      • The original Lich escapes his amber prison and attempts to use his well of power to restore his power and bring about the end of Ooo, only to be foiled by Finn. The Lich then possesses Princess Bubblegum to use her body for his purposes. The Lich later murders Billy in retribution for his past defeat, wearing his skin to trick Finn into giving him the Enchiridion so he can enter the Time Room and wish for the extinction of all life across the multiverse. The Lich spitefully murders Prismo and his physical body and tries to use an army of cosmic breakouts to destroy a billion worlds across the universe, turned into a harmless baby named Sweet P afterwards.
      • The "Farmworld" incarnation of the Lich is an alternate version that possessed the body of an alternate version of Jake the Dog. The Lich manipulates his world's version of a grief-stricken Finn to gain access to The Multiverse, planning to slaughter the denizens of every reality, over and over again, until he has made a "mountain of broken bodies" from his victims. Escaping into the world of Ooo, the Lich mentally tortures Sweet P for nights on end to try and turn him back into the original Lich. After his final death, the Lich resurfaces in Distant Lands, where Farmworld Lich manipulates New Death into killing his father and uses him as a puppet to annihilate the cycle of reincarnation, stopping new life from blooming.
    • "Preboot" & Season 8's "Islands" miniseries: Dr. Gross was formerly a scientist and doctor on the series of islands founded by Minerva Campbell as a refuge for the remnants of humanity, training children to become "Seekers", with no hesitation in brainwashing them and having them brutalize their own friends to prevent any escape from the islands. Dr. Gross eventually turned to twisted experiments on sapient beings, with her recklessness accidentally unleashing a virus that killed off two-thirds of all humanity on the islands — to her complete apathy. Escaping the islands, Gross continued her experiments, scheming to return to the islands and forcibly augment all humanity into cybernetic abominations like herself, even trying to cut apart Finn and his friends to use as raw material. An unfeeling scientist with zero empathy, Dr. Gross proves that, sometimes, Humans Are the Real Monsters.
    • Distant Lands "Wizard City": Dr. Caledonius, supposedly a Cool Teacher at Wizard City's school for preeminent young wizards, is actually a deranged cult leader worshiping an eldritch horror named Coconteppi. Caledonius takes an obsessive interest in the amnesiac, childlike Peppermint Butler, knowing he used to be the most evil dark wizard in Ooo's history, and so manipulates and corrupts him into drinking the ichor of Coconteppi and becoming the monster's host, all so that he'll annihilate Wizard City and usher in the "Second Age of Terror". Caledonius has no compunction murdering her own teenaged students; she murders Spader in a failed ritual to summon Coconteppi, then remorselessly orders Peppermint's friend Cadebra murdered when she tries to help him break out of Coconteppi's influence.
  • Adventures of the Galaxy Rangers: The Queen of the Crown is an evil sorceress who starts off by ambushing Kirwin, and putting a heavy bounty on humans for every two-bit thug in the galaxy. She is mashing the humans down to power Slaver Lords, artificial creatures through which she can see, hear, and administer her Empire; this is not only an exceedingly painful process, but leaves the victim fully awake and aware of what's happened. The Queen also slaughtered millions on the planet of Tortuna, leaving a few domed cities behind in a lot of wasteland. She was hunting humans because the last race she used to power Slaver Lords has been hunted to near-extinction and she needed replacements. If that wasn't bad enough, she enslaves an entire planet, making the inhabitants work in concentration camp conditions to build a massive hyperspace cannon she uses to blow a chunk out of Earth's moon, threatening to do worse to Earth unless they gave her 5,000 humans in tribute. On a personal level, she uses the only psychocrystal she's made from a human — Zach's wife — to commit Mind Rape nightly on both of them.
  • Agent Elvis: Robert Goulet is a "Tony Award-winning pompous prick" who initially just appears to be Elvis Presley's Sitcom Arch-Nemesis in the world of music, but soon reveals himself to be an egotistical monster who would sell out the entire world out of little more than spite and envy. Once the Number Two of The Central Bureau, Goulet helped oversee their tortuous experiments on Elvis to harness his musical abilities for mind control, only to instead end up with a device that reverted subjects to a primal, murderous state. Betraying TCB to provide the device to Gabriel Wolf, which would lead to the technology being tested at numerous concerts to instigate bloody massacres, Goulet uses the weapon to target several Elvis shows before helping attempt to hijack the global broadcast of the Aloha from Hawaii production. Intent on seeing millions of Elvis fans slaughtered across the world through this act, Goulet proves himself to be exactly the "bag of shit" that Elvis proclaims him to be in his efforts to see his rival's reputation burned to the ground.
  • Alfred J. Kwak's two-parter "The Strange Bottle" and "Flying Carpet": The Evil Spirit Of Darkness is an evil genie who terrorized the land long ago for fun, causing droughts, floods, storms, plagues, and fires, destroying cities and killing many people. After The Almighty One sealed the spirit inside a bottle, the spirit vowed that when it was freed, it would kill whoever freed it to spite the god who punished it previously, before returning to its homeland to terrorize the people once more. When Dolf and Alfred free the spirit, it tries to eat Alfred despite the fact that he is a child.
  • Alienators: Evolution Continues: General Granger is a high-ranking general with ambitions of establishing a New World Order to control humanity, believing that humanity is prone to violence and self-destruction without the guidance of a strong leader. To achieve this goal, Granger allies with SCOPES and the Genus, supplying the Genus with missiles to infect the entire planet and breaking SCOPES out when the latter is captured by the Alienators. During the series finale, Granger plans to launch more missiles to spread the Genus across the planet and planning to give the Eastern Hemisphere to SCOPES so he can rule over what's left. When the Alienators foil project Alpha-Omega, Granger tries to restart the project through using the satellite defense system to launch a nuclear strike on the moon so the Genus cells there could be spread across Earth and successfully acquires most of the launch code. During the final battle, when Ira reveals to Granger that SCOPES has no intention of keeping his end of the bargain, Granger refuses to listen and continues to believe that SCOPES was under his control.
  • Angel Wars: Morg was once a heroic angel, but betrayed his kind to ally with the satanic Dragon for power. Failing to kill his best friend Michael and deliver a powerful Foundation Stone to the Dragon, Morg was imprisoned for ages before escaping by nearly driving a man insane and feasting on his negative energy. Morg immediately murders his former partner Graven upon escape and steals back the Foundation Stone, using it to nearly wipe out a moon colony of humans and following it up by trying to destroy all life on Earth. After merging with the Foundation Stone, Morg begins devouring everything and everyone in sight, primarily his own minions, and then reveals his goal to ensure that nothing in the universe is "higher" than himself by devouring all life in existence.
  • Animalia: Wooster Q. Weasel — better known as the Creeper — is the former king of Animalia, and brings an unprecedented darkness to a series that had otherwise been very lighthearted. Having become drunk on his own power during his tenure as king, and exiled for the safety of Animalia as a whole, the Creeper resolves to take back the power of the Core regardless of the consequences to Animalia. A refined manipulator, the Creeper attempts to start a war in Animalia through Tyrannicus, and after this fails, moves on to tricking his old friend King Livingstone and his young friend by pretending to undergo an epiphany, only to backstab the two and try and have them blown away to their deaths into the Winds of No Return purely out of spite. The series finale sees the Creeper at his nastiest: Upon taking the power of the Core and resuming control of Animalia, the Creeper brainwashes and captures all resistance and ultimately strives to use the knowledge contained within the Corespore to travel to and subject other worlds entirely — at the consequence of killing off everyone in Animalia.
  • The Animals of Farthing Wood Season 2: The blue fox Scarface is a ruthless bully who begins killing the Farthing animals when he can get away with it. After having a litter of children with his mate, Lady Blue, Scarface becomes incensed by his rival Fox's children and murders Fox's young daughter Dreamer. When he has an excuse, Scarface rallies his other foxes and kills one of the Farthing rabbits, hunting the Farthing animals down and intending to massacre them one and all. When defeated by Fox, he returns to kill another of the rabbits, showing his lack of honor and refusal to ever stop. Even his son Ranger admits upon attempting to broker peace that his father would murder him should he know of the talks. Vicious, cruel and without any remorse or care for others, Scarface embodies the sheer savagery of the wild, even in a place of peace such as White Deer Park.
  • Archer: Sterling Archer dreams up some pretty heinous versions of his then-Arch-Enemy Barry Dylan.
    • Dreamland: "Dutch" Dylan is a psychopathic enforcer to gangster Len Trexler. Having killed Archer's partner just to watch him die, Dutch enjoys performing hits and dissolves his victims' bodies in acid to sate his blood thirst. After being crippled and having his limbs replaced with mechanical ones, Dutch takes vengeance upon Trexler for the surgery by killing all of his underlings to pose their corpses in a grisly parody of The Last Supper, and later tries to murder Archer and all of his allies to avenge his injury.
    • 1999: Barry-6 is an upbeat and sociopathic robot, slaver, and pirate, leading the Dri'n in terrorizing the galaxy while casually murdering or sacrificing his men. Raiding transport ships and either killing or selling the occupants into slavery, Barry-6's forces also try to commit genocide against the endangered Grimalkian race in their attempt to skin them alive for their fur coats. Holding a particular grudge against Archer for sleeping with his fiancée years ago, Barry-6 sells his friends into lethal Gladiator Games where they are forced to fight to the death, tortures Archer with electricity, and endangers his entire team with destruction to force him into a final duel to the death.
  • Argai: The Prophecy: Dark Queen Orial is a serpentine sorceress whose ultimate goal is to one day reign in Hell as the bride of Lucifer. Having made a Deal with the Devil for eternal life, Orial maintains her youth by regularly placing young maidens in magical comas, with one of her victims being Angele, the fiancée of Prince Argaï. Originally a marauding medieval warlord, Orial eventually conquered the world in a bloody campaign that killed a tenth of the population of the Earth, which she then turned into a dystopic Police State in which anyone who steps out of line is either executed or condemned to a Hellhole Prison. Orial regularly disposes of her own allies at the slightest provocation, and when she learns that Argaï is destined to slay her, she resorts to increasingly extreme attempts at eliminating him and his allies, like burning entire villages, leveling a city block, and razing all of Chinatown. In the end, when she realizes that she has been beaten with no way out, Orial spitefully tries to blow up the Earth.
  • Babar: The unnamed hunter, the Big Bad of the first five episodes, focusing on Babar's childhood, is the darkest and cruelest villain in this mostly lighthearted series. Initially seeming to be a simple Evil Poacher, who relentlessly hunts a herd of elephants, one of his successful kills was Babar's own mother. The hunter continues this, even when he witnesses multiple instances of the animals being sapient, eventually calling in a bigger team of poachers to wage war on the animals. His only apparent motivations are greed and wounded pride over being beaten by a young Babar. This eventually comes to a head when he has the rhino village destroyed, and sets fire to the jungle to wipe out all its inhabitants. When the fire is beaten back, the hunter dies defiantly screaming how he'll stop at nothing to destroy the animals.
  • Big Guy and Rusty the Boy Robot:
    • "The Inside Scoop" & "Nephew of Neugog": Dr. Hieronymous Neugog was a wannabe Mad Scientist before a freak accident transformed him into a brain-eating monstrosity. Neugog sucks out the minds of many unfortunate people who get in his way, even people Neugog admits have no valuable knowledge to him whatsoever, and at the end of his first episode plans to attack a convention filled with hundreds of brilliant minds for him to snack upon. Even when a rival brain-eater forces Neugog to team up with the heroes, Neugog betrays them at his earliest convenience and attempts to take all the minds his rival has devoured for himself.
    • "The Champ": Po the Obliterator is a posturing brute out to prove himself as the best fighter in the universe. Po travels to a world and threatens to destroy it unless its best fighter challenges him to a duel. After invariably defeating his opponent through cheating if need be, Po takes his fallen foe as a frozen trophy, kept in containers lining his ship for him to mock as he so pleases. Arriving on Earth and forcing the Big Guy into combat, Po flies into a rage when Rusty saves the Big Guy armor from Po's captivity, prompting Po to rampage on Robopolis and threaten to destroy the whole planet. Even when beaten down by Big Guy and showed mercy, Po feigns remorse only to try to wipe out Earth anyway "just for laughs" out of spite at being defeated.
  • Blake and Mortimer: Colonel Olrik is even more fiendish than in the comics. A mercenary willing to work for the highest bidder, Olrik is first introduced working as a military adviser for an empire and leads bombing runs against several major cities, devastating them and killing thousands in the process. Olrik wants to steal Professor Mortimer's new invention the Swordfish plane, betray the Empire and rule the world himself. After that scheme is foiled, Olrik returns, leads a military coup that turns a democratic country into a dictatorship and joins forces with a rogue general in Atlantis, trying to encourage a military coup there as well that would leave hundreds dead, just to plunder Atlantis's resources. Olrik later shows up and commissions a Mad Scientist to build a machine that controls the weather. Olrik uses this machine to cause disasters across Europe, until he unveils his master plan to blanket Western Europe in a toxic fog, killing everyone, so that a foreign power can successfully invade. Much later Olrik is seemingly killed after trying to using alchemy to gain immortality, but he is merely banished to an alternate world, where he takes over and rules as a dictator. Wanting revenge for being banished from the Earth, Olrik plans to use a powerful moon medallion in a ritual that would destroy the Earth.
  • Blue Eye Samurai:
    • Abijah Fowler is a ruthless, cruel, and wantonly bloodthirsty Irish Arms Dealer and one of the Four White Devils who plots the takeover of Japan. Once a boy who lost his family to famine, Fowler turned to a new outlook on life where nobody else but himself mattered. Growing sadistic over the years, Fowler plots a violent coup against the Shogun that will see thousands of his men dead and the crowning of a puppet shogun for Fowler to control Japan from the shadows, with Fowler hoping to personally kill the Shogun and his entire family. Having birthed plenty of bastard "half-breed" children during his time in Japan, Fowler has them and their mothers killed, their bones littering his underground tunnels. Using his traitorous henchmen as target practice after their failed attempt to kill him, Fowler ultimately wishes to open up Japan's borders to destroy the country's culture as his insurrection leads Edo to ruin. With the death of his own sister treated as a mere afterthought, Fowler's newfound philosophy is nothing more than an excuse to hurt those he deems beneath him.
    • Heiji Shindo is Fowler's fellow mastermind in concocting the heinous plan to overthrow the Shogun. A seemingly-respectable lord who uses his political power to run a variety of crime rings involving Human Trafficking and gun smuggling, Shindo serves as Fowler's hands and feet in setting the stage for their grand plan to slaughter thousands of people in Edo. Shindo enjoys overseeing brutal torture sessions of prisoners, notably subjecting Taigen to days of it, and he routinely forces men who swear allegiance to him to chop their own thumbs off for his "collection". Fostering ambitions of his own, Shindo tries to betray and murder Fowler to carry out their plan for himself, only to let the blame for the treachery fall on someone else to save his own skin when Fowler survives. When Fowler's invasion of Edo begins, Shindo infiltrates the Shogun's castle and murders multiple innocents to open the way for Fowler's continued slaughter.
    • "Peculiarities" & "The Tale of the Ronin and the Bride": Boss Hamata is a brutal crime lord near the district where benevolent brothel owner Madam Kaji operates. A believer in ruthless, overwhelming force, Hamata slaughters anyone who opposes him and everyone connected to them in a scorched earth policy he has practiced many times. When he took a shine to the mute girl Kinuyo, Hamata had her taken to be his personal concubine against her and Kaji's will. Upon Kinuyo's death at the hands of Mizu, Hamata leads his forces to have Kaji and her brothel butchered.
  • Cadillacs and Dinosaurs :
    • Hammer Terhune is the psychopathic minion to Governor Scharnhorst. Trying to discredit Jack Tenrec's idea of promoting a balance between humans and nature, Hammer uses a sonic transmitter to torment a T-Rex and has it attack nearby settlements, then tries to cause a bunch of Triceratops to stampede and kill people in a mining town. Unhappy with taking orders, Hammer uses a killer satellite to try and destroy the City in the Sea, so that he can take over what's left. Hammer later discovers a boy who can control dinosaurs and tries to test the boy's skills by throwing him into a pit with a hungry raptor and seeing if he can control it. Finally, Hammer uses some dynamite to try to kill some dinosaurs, but causes a wildfire instead, which is heading towards some gas wells, which would eventually cause an explosion that would devastate the jungle, resulting in mass starvation for the City in the Sea. Scharnhorst orders Hammer to work with Tenrec to use nitroglycerine to save the jungle, but Hammer intends to kill Tenrec anyway and steal the nitroglycerin for himself, not caring that his actions could have endangered millions of lives.
    • "Duel": Sean Russel is Jack Tenrac's old friend and rival. Russel sabotages Tenrac's car and steals a helicopter engine from him. He uses his new helicopter to go to the home of the Grith, a race of peaceful sapient lizard creatures who communicate through telepathy, and steals the life stone, a gem they need to survive. Russel uses the stone to summon several dinosaurs to a valley. Russel captures Tenrac and says he invited Hammer Terhune and his brothers to come and slaughter both the dinosaurs and the Grith, planning to sell their meat and bones on the black market. Tenrac lectures Russel about selling out the Grith to make a profit and Russel seems to briefly feel guilty over it, but quickly decides he cares far more about money then his old beliefs and continues with his genocidal scheme.
  • Captain Planet and the Planeteers has two Eco-Villains who stand out, and are proudly motivated more by sadistic enjoyment than mere greed:
    • Zarm, the Spirit of War and Destruction, is arguably the strongest and most deadly adversary of Gaia and the Planeteers. A former Spirit of the Earth exiled by Gaia, Zarm dedicates himself to bringing ruin and destruction in all forms to Gaia and all she protects out of vengeful spite, having consumed at least one planet to the tides of destruction and constantly attempting to do the same to Earth. Zarm attempts to initiate all-out nuclear war on Earth; painfully reverts Gaia to a withered old lady incapable of stopping the Earth from dying and taking over the Earth for a ten-year-period of time where the Earth has become desiccated and ruined; coins a strategy he calls "Scorched Earth" by convincing world leaders to obliterate their own land and people — and claims to have been "a part of every important tyrant in history" — and nearly dooms the Planeteers' efforts to stop an alternate timeline where the Eco-Villains' descendants rule the planet by smugly ordering a young girl Ma-Ti saves murdered. A sadist drunk on his own capacity for destruction, Zarm is one of the single greatest sources of human misery within the show.
    • The appropriately-named Verminous Skumm is a humanoid rat-man who, despite being far less powerful than Zarm, manages to be just as evil. Taking a sick pleasure in the polluted and festering, Skumm's schemes vary from willingly endangering and trying to destroy entire cities, and include deliberately trying to destroy an entire city with a cloud of acid rain and flooding Venice with oversized, carnivorous rats; peddling mind-altering drugs and even murdering Linka's cousin Boris through them; attempting to bait two sides of the Arab–Israeli Conflict into using a nuclear bomb in Jerusalem Mount, as well as bringing nukes into The Troubles and apartheid South Africa; and attempting to flood the entire world with his "Rat Rot" chemical to turn everyone into his mutated rat slaves. Skumm's end goal is to destroy the civilized world and enslave what remains to his mutated Rat Men followers to rule over them all as a king. Happily admitting "I'm ignorance; I'm fear; I'm hate", and taking delight in everything from ruining the life of a single person — a teenager with AIDS — for giggles, to the attempted annihilation of millions of lives, Skumm stands out as the darkest of the recurring Eco-Villains due to his propensity to target people rather than the environment.
  • Captain Simian and the Space Monkeys: Lord Nebula is a half-human half-black hole creature who seeks the destruction of the entire universe so he can rebuild it in his own image. Nebula orders his henchman Rhesus-2 to acquire the anti-force, but ends up tricked and reduced to a humanoid form. During the series, Nebula frequently threatens to kill Rhesus-2 when he fails him and shows how awful he truly is when it is revealed that when Rhesus-1 failed him too many times, Nebula violently killed and disposed of him. To complete his plan, Nebula captures Simian's crew, but since Simian was able to escape, Nebula orders Rhesus-2 to torture them until they give up Simian's location. When Simian does return and promises to give up the part he needs, Nebula reveals to Rhesus-2 that he lied to him and was never planning on giving him a Pocket Universe to rule over.
  • Chaotic
    • Season 2 (M'arrillian Invasion): Aa'une the Oligarch is supreme leader of the M'arrillian tribe and mastermind of their invasion of Perim. After Phelphor opens the Door of the Deepmines and frees the M'arrillians from their imprisonment, Aa'une sends his soldiers to take control of Perim's creatures and flood the land with the water in which only M'arrillians can live. In the season finale, Aa'une lures Maxxor into his domain and manipulates him into bringing Aa'une to Lake Bakker, where he becomes invincible. Aa'une tortures and tries to kill Maxxor and Chaor while giving his soldiers the power to brainwash all people of Kiru City, planning to melt the Glacier Planes and flood the whole of Perim.
    • "Son of the Spiritlands" series finale: Vitog is a cruel Spirit Creature of War who terrorised the Spiritlands until he was defeated and reduced to a non-corporeal form by Tangath Toborn. Vitog comes to Perim and spreads destruction across the land, at one point attacking an innocent village, threatening to completely destroy Perim unless Tangath Toborn fights him. When Tangath Toborn faces him, Vitog uses Mugic to gain the upper hand, intent on completely destroying both him and Perim.
  • Chuck Norris: Karate Kommandos: The Claw is the leader of VULTURE, a cabinet of terrorists willing to wreak vast destruction under the Claw's firm eye in their goal of world domination. The Claw, throughout the series, hijacks an undersea lab to use its powers to try and wipe out coastal cities; tries to seize a NATO memory core to disable their defenses; coldly orders Norris's young friend Too Much murdered; attempts to seize a powerful laser robot to use it to attack and devastate Tokyo and orders a train full of people transporting it spitefully destroyed; and steals a shuttle to try and extort billions of dollars out of all the world's major powers lest he use a Kill Sat to obliterate all of the capital cities of each powerful country around the world. Throughout the series, the Claw regularly tortures and murders his own minions with aplomb and is happy to claim as many civilian lives as it takes to further his own nefarious agenda.
  • Class of the Titans: The Titan Cronus, the God of Time, once warred with his fellow gods for control of the world before being imprisoned in Tartarus. Escaping in the present, Cronus attempts to reassert dominance and reconquer both Mount Olympus and Earth. Over the series, Cronus has attempted various apocalyptic schemes, which include using the Antikythera Device to sink the continents beneath the waves; mutating a group of soldiers into ant monsters to conquer Olympus; plotting to use the Time Piece of Zeus to erase humanity from existence; and poisoning the Tree of Immortality to wipe out his fellow gods. With nothing but hatred for his children and the other gods, Cronus is utterly brutal and merciless in his tactics, which include torturing and trying to kill his own children while throwing the world into chaos and disarray. Cronus eventually gets tired of the human heroes resisting him and makes it a point to attempt to exterminate the entire human race in retribution. At other points, Cronus releases the savage werewolf Lycaon from imprisonment to eat "whomever he may please" and tries to get his mother Gaea to kill Zeus for him. Sophisticated, suave, seemingly polite, and never at loss for a vicious plan, Cronus repeatedly proves how nothing will stand in the way of his goals of domination and destruction.
  • Code Lyoko: XANA is a rogue multi-agent program living on the virtual world Lyoko that evolved to the point of achieving sapience. Gaining a desire to rule over and/or destroy humanity, XANA tries to kill its creator, Franz Hopper, as well as his daughter Aelita. Trapped inside the supercomputer for a decade, once revived, XANA regularly launches many vicious schemes upon the real world, not caring about the sheer amounts of potential casualties that would result from the attacks. XANA shifts strategies to absorbing Aelita's memory to gain the power to leave the supercomputer and into the network, the success of which nearly killing Aelita in the process. Using the internet to access supercomputers across the world, XANA gradually builds a robot army to rule over humanity. In the mean time, XANA tries and almost succeeds in destroying Lyoko, taking William as a slave. When Lyoko is revived, XANA decides to lure out and kill Franz Hopper by using Aelita as bait and plans on keeping the latter as its eternal prisoner. In the one episode where it appears before the heroes, XANA shows sadistic enjoyment in trying to kill them.
  • C.O.P.S. (1988)'s "The Case of the Lowest Crime": Addictem is a drug lord flooding Empire City with a new drug called Crystal Twysts. Addictem creates 200 Crystal Twyst addicts within a week, with many of them ending up hospitalized or in mental institutions; Crystal Twysts are also deadly in large doses. Addictem offers to become partners with Empire City's main crime lord, Big Boss. Big Boss is disgusted by Addictem's business practices and has him thrown out of his office. Addictem has no limits regarding who he sells his drugs to, willing to sell them to 2 pre-teen girls.
  • Courage the Cowardly Dog:
    • Katz, Courage's most recurring foe, is a ruthless and sadistic Serial Killer. While his motives tend to change, each episode he appears in generally has him using some sort of illegitimate business as a front for committing murders, and his list of past victims is strongly implied to be quite long. In his first appearance, he ran a Hell Hotel where he fed all his guests to spiders. Other episodes have seen Katz transforming the guests of his health spa into machines and forcing them to fight to the death for his entertainment; attempting to turn Muriel into candy as revenge for her always beating him in a candy-making competition; and trying to blow up a submarine full of people to drive a rival vacation submarine company out of business. Not content with simply killing Courage, Katz sometimes challenges him to some sort of game solely so that he can inflict more physical pain and drag out the dog's suffering for as long as he can.
    • "Queen of the Black Puddle": The Black Puddle Queen is a man-eating siren who uses bodies of water to travel from her underwater kingdom and hunt for humans. With her Compelling Voice and sultry appearance, the Queen hypnotizes men into following her to her castle, where she performs a ritualistic ceremony before eating them alive. The Queen has filled her kingdom with the skeletal remains of her hundreds—if not thousands—of victims, and she tries to subject Eustace and Courage to the same fates. She later joins a villainous alliance to take Muriel hostage and destroy Courage in a slow, painful way out of nothing but annoyance that Courage thwarted the Queen's last scheme.
    • "The Great Fusilli": The Great Fusilli himself is a traveling stage magician who lured people onto his stage under the guise of making them famous actors. He would then have them perform for an imaginary audience, in order to use enchanted puppet strings to convert them into lifeless puppets, which he would then play with for his own amusement. Once Courage finds a room filled with the dozens of people he's converted into marionettes, Fusilli turns his owners Muriel and Eustace into puppets—an act not reversed by the end of the episode, causing Courage to suffer Sanity Slippage—while at the same time attempting to dispose of Courage.
    • "The Quilt Club": The Stitch Sisters, Eliza and Elisa, are the owners of an antique quilt shop and reclusive quilting club who make Muriel work day and night to pass the standards they use to admit those into their club. The club itself is a front; since the dawn of humanity the Sisters have walked the Earth, ensnaring the souls of women to prolong their own youth and binding them forever to their quilt. The souls of their victims are kept within the quilt for centuries on end, forever ripped of everything that once made them unique.
  • Cybersix: Dr. Von Reichter is a cruel scientist with two concerns: conquering the city of Meridiana, and exterminating his hated creation Cybersix. Throughout the series, Von Reichter engages in various ploys to achieve his goals, such as: resurrecting Cybersix's little brother Cyber 29 as a panther, only to wipe his mind and use him as a weapon against his sister; sending in the werewolf Elaine, who attacks civilians and transforms them into more of her kind; and making countless attempts on Cybersix's life. In the final episode, Von Reichter grows weary with his failures, and tries to wipe Meridiana and its populace off the face of the Earth with a gigantic living bomb known as the Isle of Doom, so that the rest of the world will take him seriously as a threat. Even when he is thwarted and moments from being blown to kingdom come, Von Reichter still makes one last effort to ensure Cybersix's demise by setting his remaining creations upon her.
  • Dan Dare: Pilot of the Future: The Mekon, the tyrannical ruler of the Treens from the north of Venus, aims to conquer the universe. Under the Mekon's rule, the Treens wage war on the peaceful Therons, with Treen children experimented on to create the perfect soldiers, one of whom is his bodyguard Sondar. When a human mission on Venus is intercepted by his forces, the Mekon plots to use technology from their ship to destroy the Therons and invade Earth. When Dan Dare punches him, the Mekon attempts to painfully execute him, as well as Sondar for his slow reaction. The Mekon then tries to enslave both the Therons and Earth: Methods include include using an ancient superweapon; trying to starve the Therons; and weaponizing a disease, almost destroying the afflicted village in the process. When the Mekon's campaign to Jupiter ends with him destroying a peaceful colony and being pursued by more powerful enemies, he manipulates his way into Space Fleet Command and tries to launch nuclear warheads against Jupiter. After his mining of the north of Venus leaves it uninhabitable, the Mekon joins forces with the treacherous Earth senator to fake his death and frame Dan for a war crime so Earth will lower its defences, allowing his fleet to attack Earth—reducing entire cities to rubble. When forced to call off the invasion, the Mekon sends a satellite crashing into Earth, gloating that the entire planet would be destroyed.
  • Delta State: Sven Ragnar is easily the worst of all the Rifters that appeared in this series. Sven is a super Rifter, in charge of the Rifter invasion of the human world, and is opposed by Broody and his proteges: Martin, Phillip, Claire and Luna. In his first appearance, Sven kills one his Rifter minions for lounging around in a hotel room instead of performing her appointed tasks. Later he kills a psychic that could detect Rifters, fearing she is a threat to his invasion plans. In another scheme, Sven uses his shapeshifting powers to impersonate a hospital administrator, who is pushing a new microchip that would be implanted in the human brain, claiming it had medical benefits, but which in reality this chip simply allows Rifters to take over human minds more quickly. 20% of the patients who received this chip would have been taken over by Rifters, while the rest would die. Sven also kills Martin's father to prevent Martin from discovering his past. Sven decides to torment Phillip, mocking him over the fact that his mother abandoned him. Sven's sister Marie falls in love with Phillip and saves him from Sven's wrath, so Sven kills her. Broody eventually revels that he himself is a Rifter and has been training his students to fight Rifters so they can be powerful enough to kill him, before his Rifter energy overwhelms him and causes him to explode. Sven does everything in his power to stop Broody's students from preventing this disaster.
  • Di-Gata Defenders:
    • Lord Nazmul was a member of the Wizards of Yan, the protectors of RaDos. Obsessed with unlocking the secret of immortality, Nazmul betrayed his brother Alnar and the other Wizards and freed the Megalith, which he tried to use to turn him into the eternal ruler of RaDos. Nazmul killed many of his old allies during his campaign, which ended when the Di-Gata Defenders and the remaining Wizards sacrificed themselves to defeat him and seal away the Megalith. Reduced to a shadow of his former self, Nazmul becomes reliant on Lord Brackus and his Yin-Tos Army to do his bidding and bring about the return of the Megalith. Since his body is failing him, Nazmul tries to possess Kara, the youngest member of the new Di-Gata Defenders, and when that fails, he resorts to taking over his fanatically loyal servant, Malco. After realizing that Brackus is untrustworthy, Nazmul kills a prisoner in front of him as an example, makes failed attempts on his life, and eventually condemns him to the Dark Realm after terrorizing the Yin-Tos Army into siding with him over Brackus. Nazmul is later trapped in the Nova Stone, but is released from it by Malco, who offers up most of his own life energy to restore Nazmul. Nazmul thanks Malco by tossing him into an abyss before trying to feed on the young Di-Gata Defender trainee Rion.
    • "The Lost Children": The Professor lost his job at a prestigious university due to his "crazy" belief that the RaDosians were descended from aliens that had immigrated to RaDos from a theoretical RaDos Prime. After triangulating the approximate location of the Prime RaDosians' lost ship, the Professor abducts children to use as slaves to help him dig it up, having discovered that the ship is housing an adult-killing contagion called the Toten' Ka Virus. When he finally finds the ship, the Professor orders his henchmen to kill all of the child slaves while he boards the vessel, followed by Seth and Rion. After incapacitating the two Defenders, the Professor reveals that he is going to fly the ship to the university to show up all of his old colleagues before killing them and all of the planet's other adults by releasing the virus, leaving a world of only children for him to mold "in my ways." When Rion damages the ship's engine, the Professor refuses to evacuate it, and instead tries to crash it in a way that is guaranteed to release the virus on an unsuspecting RaDos.
  • Dinofroz: Neceron is the lord of all dragons and the Big Bad of Season 1. Desiring more power, Neceron broke the treaty between dinosaurs and dragons and declared war on the dinosaurs. He then spent several years ordering his dragon armies to eradicate his foes and kidnap humans to use as slave labor. When the Dinofroz arrive and start interfering with Neceron's plans, Neceron repeatedly tries to destroy them all, even going as far as nearly drowning the residents in a village just to lure them out of hiding. After one of his generals tries to start a rebellion, Neceron and his army simply kill all of the rebels without hesitation. Upon finding out that the Dinofroz are merely four young boys, Neceron and his dragons kidnap three of them, and he threatens to kill them all one by one if they don't surrender. He later drains all of the power from his three loyal generals and leaves them for dead before going after Tom Carter in his Dinofroz form. Once Neceron begins to lose the fight, he tries to make Tom submit by threatening to murder his father right in front of him.
  • Disenchantment: Queen Dagmar, mother of Princess Bean, murdered her own parents to seize control of her kingdom. To fulfill a prophecy for hell, Dagmar screwed a crown onto her brother's head which left him with severe brain damage and later tried to poison her husband King Zog. When a switch left Dagmar turned to stone, she revives her plan upon Bean bringing her back to life and turns almost everyone in the kingdom to stone, which she expects to be fatal. Murdering her own siblings and also trying to kill Bean, Dagmar creates an evil clone of her daughter and gleefully tricks Bean into seemingly murdering her own girlfriend. Upon defeat, Dagmar attempts to ensure that Bean's friend Elfo dies in the process, being so wicked that even Satan himself fears her.
  • DOTA: Dragon's Blood: Terrorblade is a vicious, evil demon who collaborates with the Invoker to start a holy war from the followers of Selemene against the elves and create mass bloodshed to weaken the worship of Selemene. Terrorblade gleefully crafts conflict to murder the eldest dragons and steal their souls. Intending on destroying the world and recreating it in his image, Terrorblade plans to make a world of pure darkness and hellish torment for all living things.
  • Double Dragon (1993): The Shadow Master is the leader of the Shadow Warriors, and the uncle of the Double Dragons, Billy and Jimmy Lee. Shortly after the brothers were born, the Shadow Master trapped their mother in the Abyss and abducted Jimmy, raising him to be his second-in-command, Shadow Boss. Despite promising his sister that he would never harm Jimmy, the Shadow Master callously orders him killed when Jimmy fails him, which spurs Jimmy into joining forces with the heroic Billy. Ruling the criminal underworld of Metro City with an iron fist, the Shadow Master has flooded the city's streets with drugs and weapons, enslaved most of its marginalized mutant population, and terrorized its citizens with illusions of their greatest fears and a massive beast called the Shadowmonster. The Shadow Master's other plots include hacking all of the world's banks; consuming minds to increase his own intellect; and starting a race war between mutants and humans by framing the mutants for the abduction of a little blind girl, who he then tries to kill. Any minion who displeases the Shadow Master is magically added to the Shadow Mural, a tapestry which is covered in dozens of victims, all of them frozen mid-scream.
  • Dragon Booster: Armeggaddon was the Emperor of the Black Draconium Empire who lived 3,000 years ago and was responsible for triggering the first Dragon-Human War that nearly brought both races to extinction, before he was defeated by being trapped within the Shadow Track. Accidentally awakened in the present day, Armeggaddon selects Moordryd Paynn to be his apprentice, training him to become the Shadow Booster and encouraging increasingly immoral actions including killing, which horrifies Moordryd and drives him away. He reveals he intends to start another Dragon-Human War to wipe out all life on the planet but himself.
  • Dragon Flyz: Dreadwing is a cruel, mutant warlord determined to conquer Earth and sky by any means necesary. In his war against the Dragon Flyz and the city of Airlandis, Dreadwing constantly schemes to either conquer or destroy the latter and its humans. Dreadwing tries to have the eggs of Dragons allied with Airlandis stolen and mutated into his soldiers before tricking a rival warlord into allying with him to attack Airlandis, only to betray him and his soldiers. Dreadwing has Z'neth captured and brainwashed into believing he is Dreadwing's son, sending him to attack Airlandis. His other plots include unleashing a sleeping sickness on Dragons to leave Airlandis defenseless; taking the Airlandiean settlement hostage and threatening to kill everyone if city doesn't surrender to him; threatening to use nuclear missiles to destroy Airlandis; and tricking a giant Dragon into attacking it. Never one to miss an opportunity for cruelty, Dreadwing constantly threatens his minions with death; and has Dramen Dragonator Dram forced to fight to the death in a cage to free the village of innocent Dramen, planning to drop them all into lava if Dram wins. When a group of kids try to help the Dragon Flyz when Dreadwing creates a toxin to turn them into monsters, Dreadwing uses them as bait and human shields against the heroes. In the penultimate episode, Dreadwing captures Z'neth and Councilman Joshua, putting them in the Kangaroo Court, leaving the latter without water for days to force him to testify in Dreadwing's favor.
  • The Dragon Prince (includes Bloodmoon Huntress comic & "The Queen's Mercy"): The wicked and treacherous Kim'dael is an ancient Moonshadow elf who has survived with her youth for centuries by murdering innocents and drinking their blood during the Blood Moon. Thought to be just a myth, a young Rayla witnesses her trying to kill a family of elves with no compunction at killing children. Upon her plan being foiled, Kim'dael tries to murder Rayla as well. Kim'dael is later recruited by the renegade Sun Elf prince Karim to kill Queen Janai under promise of freeing her from bondage. Kim'dael proceeds to massacre Janai's guards and attempts to deliver Janai to execution, with Janai protesting her brother's plot to unleash such a monster on the world.
  • Exo Squad:
    • Governor General Phaeton is the falsely-noble despotic ruler of the Neosapien Empire who manipulates his people into throwing their lives away to increase his personal power. Once a Neosapien rebel, Phaeton cowardly sold out his cohorts to save his own skin, then rose to power while ordering the genocide of humanity while consolidating his grip on the Neosapiens. Running brutal death camps, Phaeton has any who resist his orders taken there to be killed and proves a horrific war criminal, with tactics including forced starvation and labor. With cloning technology, Phaeton takes advantage of an unending supply of troops and cruelly executes his commanders for even minor failures only to replace and replenish his army. A completely disgusting madman, Phaeton eventually sends so many of his loyal followers to pointless deaths that even his most loyal aide abandons him when he discovers Phaeton's endgame involved wiping out his own race to guarantee victory.
    • General Draconis is the Neosapien Governor in charge of Venus. Cruel even by the brutal standards Phaeton has set for their species, Draconis doesn't even have Phaeton's pretense of trying to help the Neosapien people. Everything Draconis does is for his own advancement. Draconis enacts a scorched earth campaign on Venus, creating a planet-wide famine that wipes out the majority of the civilian population, with the few survivors sent to toil in forced labor camps. Draconis's treatment of his own race is little better, even murdering two Neo Megas assigned to him as advisors because he felt their "suggestions" undermined his absolute authority. As a contingency if Venus fell out of his control, Draconis rigged a hydrogen bomb to the city of Vesta, intending to spite his enemies by murdering thousands of human civilians. Draconis assigned a noble soldier named Thrax to detonate the bomb in order to "redeem" himself for showing mercy to an Exo Squad member. Except Draconis lied about there being a timer for the bomb, and once Thrax activated it, he and Draconis's remaining Neosapien soldiers would've died in the resulting blast. Draconis's lust for power was so great, he plotted to betray Phaeton and usurp control of the Neosapien Empire for himself. He eventually seized his chance by leaving what he thought was Phaeton to die in an exploding ship.
    • Dr. Albrecht Ketzer proves that Terrans can be just as evil as the Neosapiens. It is revealed that he turned an entire village of natives in the Amazon — as well as himself — into half-plant monstrosities, a rather horrific process. Later injecting Nara Burns with the same DNA formula he used on himself, he withholds the antidote unless the exotroopers attack a nearby Neosapien command station; while this may seem like a good cause, in reality this was for his own purposes. When the heroes point out that there were still Terrans in that area, and an attack would lead to Neosapien retaliation, Ketzer dismisses these concerns. Even worse, when the squad relents and attacks, Ketzer reveals that there is no antidote. Injecting Medusa with the same formula, Ketzer later reappears to kidnap Nara again and finish his "work" on her.
  • The Fairytaler's "The Travelling Companion": The Troll from the Magic Mountain is a sadistic fiend who enchanted a beautiful princess into being his servant. Using her beauty, Troll has countless young men lured to their deaths in a sadistic game of guessing what the princess is thinking, resulting in the creation of a giant graveyard outside the king's palace to bury the unlucky victims. When young John successfully guesses the correct answer the first two times, Troll makes his head the final answer, laughing that boy will never get it right and will die.
  • Fantomcat's "Tomb of the Fantoms": Salamander is a criminal who wants to destroy the world to get revenge for being put down and disrespected. He breaks into a laboratory and disintegrates two scientists who work there before activating a cyclotron and planning to use it to create a chain reaction that will destroy the world.
  • Final Space:
    • Invictus, the Greater-Scope Villain of the series, is an ancient, malevolent being whose only desire is destruction on a mass scale. In the beginning, it poisoned the Titans' minds, turning them against their creators. Spending millennia crafting a plan to escape Final Space, Invictus corrupts the Lord Commander and uses him as a pawn, making it indirectly responsible for the Lord Commander's worst crimes. Upon his death, Invictus takes Quinn hostage — as well as killing alternate reality versions of Gary to make them apart of its morbid collection — and possesses the primary Gary, using him to try to kill Avocato and Little Cato. Sensing Avocato as being stronger, Invictus takes him as a vessel, forcing Little Cato to shoot his own father to save Gary. Feeding on the life forces of dozens of captives, Invictus subtly manipulates Ash into betraying Team Squad, killing and maneuvering Fox's corpse to make it seem that Gary killed him. When it is released from its prison, Invictus leaves the Lord Commander to rot for all eternity before escaping Final Space to kick start the end of everything.
    • The Lord Commander is a tyrannical overlord bent on becoming a godlike being and ruling all dimensions. Throughout the series, the Lord Commander would continually demonstrate his madness, whether by ordering Avocato to destroy the country of Ventrexia; ordering his lieutenants to kill their firstborn children as a display of loyalty; corrupting a portion of the Infinity Guard to his cause; or overseeing the construction of a laser designed to expand a breach in space-time. The Lord Commander would lure his arch-enemies into a prison planet, then tries to force a possessed Little Cato to murder his adoptive father Avocato, culminating in the latter performing a Heroic Sacrifice when the Lord Commander plants a sticky bomb on his son's back. The Lord Commander then traps Mooncake in a laser machine which painfully forces him to create a portal to Final Space, which caused the Earth to be sucked into it. Resurrected by Invictus, the Lord Commander is revealed as the one who had Avocato murder Little Cato's birth family, before betraying his master in favor of merging with a Titan incubating inside the Earth's core to gain immortality. After succeeding, the Lord Commander destroys the planet from the inside, before killing numerous Titans, including the heroic Bolo.
    • "The Grand Surrender": Werthrent, the fire serpent god of Ash's homeworld, is a cruel being who demands endless sacrifices. Devouring countless innocents, including children, Werthrent keeps them alive and suffering within himself, draining their minds and turning them into agonized zombies who remain in agony forevermore.
  • Fright Krewe: Belial is a demon who feeds on fear, and schemes to bring Hell on Earth for an endless feast. Centuries ago, Belial caused a number of tragedies so he could consume the terror of innocents—from an outbreak of yellow fever that killed thousands, to burning down a schoolhouse—and when a headmistress saved some of his victims from death, Belial punished her by sealing her mouth shut and damning her ghost to haunt the school forever. Unintentionally released from a prison, Belial allies with Mayor Furst to manipulate the vampires and rougarous into a race war, planning to wipe out both groups in a brutal fashion, getting many innocents caught in the crossfire. Orchestrating Furst's death when he outlives his usefulness, Belial plans to use the Fright Krewe as his pawns to usher in an army of demons and Take Over the World.
  • Galactik Football: Bleylock is a General of Technoid who desires to rule the galaxy. Fifteen years before the series's events, Bleylock launched an attack on Clamp and Sonny Blackbones when they try to dispose the Metaflux, once the latter realize the danger of it. After Bleylock saw the Snow Kids using the Flux against the Red Tigers, Bleylock later tracks down and abducts Clamp and forces him to gather Metaflux by injecting a microphone and deadly poison inside his body. When the Pirates managed to save Clamp and retrieve the Metaflux, Bleylock kidnaps D'Jok and wants Sonny to hand over Metaflux in exchange for his son's safety. Bleylock later imprisons Sonny and threatens D'Jok to kill his father unless he makes the Snow Kids lose the finals. When the Pirates with the Technoids' help go after Bleylock and rescue Sonny, Bleylock attempts to kill Sonny and shoots his right-hand Baldwin after he was forced to reveal Bleylock's plans. Years later, Bleylock, with help of his subordinates, creates a "Netherball" sphere which absorbs the fluxes of many football players, creating The Multiflux. When the Pirates find that Bleylock is still alive and manage to get close to him, Bleylock then launches the Multiflux at the Shadow Archipelago, destroying Smog. Bleylock then frames Sonny by dropping wrecked parts of his ship. Chased by Sonny and Corso, Bleylock attempts to destroy Genesis with the Multiflux.
  • Generator Rex:
    • Van Kleiss is the ruthless dictator of Abysus, and the Arch-Enemy of Rex Salazar. Once a researcher who worked on the original nanite project with Rex's parents, Van Kleiss betrayed them and left them to die when the project went critical. After the nanite event, Van Kleiss resurfaces as a powerful EVO with the ability to drain the nanites of others and turn them into statues. Van Kleiss has his minions threaten Peter Meechum's young daughter in order to have her father start a Zombie Apocalypse across New York to create an army of minions for him to use. Van Kleiss later drains Rex of his powers to gain the ability to turn others into monstrous EVOs which he uses to target Rex's best friend. Van Kleiss also cares nothing for his subordinates and will sacrifice them if need be, or in the case of Breach painfully experiment on her to increase her abilities. Though he claims that he wishes to help create a better world for EVOs, Van Kleiss only truly cares for himself and his goal to become a god.
    • Quarry is a ruthless crime lord defined by greed and cruelty. Introduced as a gangster who uses manipulated EVO teenagers to commit crimes in his name, Quarry is quick to mistreat and even have those in service eaten alive if they fail or disobey him. After temporarily teaming up with Breach to steal a powerful disintegration weapon, Quarry turns on her and begins using the device to wreak devastation throughout Hong Kong, hoping to then sell the weapon to the highest bidder without a care to the mass death it will cause. In his final showdown against Rex, Quarry reaches his most depraved depths as he tricks many children into being the unwitting slavers of mind-controlled EVOs, convincing the kids they are just playing arcade games while using them to force the EVOs to do Quarry's bidding. Throughout it all, the controlled victims are fully aware they are being controlled, but unable to do anything to save themselves.
    • Dr. Fell is a ruthless scientist who wants to wholly expunge EVOs and their nanite infection from the planet. The former chief scientist of Providence, Fell disregarded his compatriots' desires to more benevolently study the EVOs, instead painfully experimenting on and dissecting the EVOs on a molecular level. Even when the young EVO boy Rex was discovered to have the capability of curing nanites in a natural, painless way, Fell refused to show mercy and chose to attempt vivisection on Rex. Returning years later in a tie-in comic where he has continued his EVO experiments as a rogue operative, Fell tries to dissect a captive Circe and nearly kills multiple Providence agents for stopping him. Fell's final appearance sees him wreaking havoc in a city with a giant robot.
    • "A Family Holiday": Dr. Branden Moses is the greedy head of Moses Labs. Moses fakes a cure for EVO mutations and convinces dozens of functional but deformed innocent EVOs to sign up for it, including Dr. Holiday's sister. Moses is lying though, and instead horrifically experiments on them and turns then into living bioweapons to be sold to the highest bidder.
  • Gladiators: Canidia, High Priestess of Anubis, is a scheming fanatic who dreams of reducing humanity to undead slaves of her master. Manipulating the ambitious centurion Catilius, Canidia has him kill Prince Prospero and try to kill infant Ali, leading to the death of his father and imprisonment of his mother. Planning to take over the Roman Empire, Canidia has Emperor Hadrian slowly poisoned and schemes with Catilius to have Prince Marcus killed. Canidia sends her champion Gutta to assist Catilius in the tournament for the Princess Domithia's hand. Canidia constantly tries to destroy Ali during his challenges, at one point attempting to poison him using a vision of his mother, and eventually causing an earthquake that destroys Rhodes. Disguising herself as Ali's mother Niobe, Canidia tries to manipulate him into killing Hadrian, before transforming into a jackal demon and planning to destroy Rome out of spite.
  • The Greatest Adventure: Stories from the Bible's "Queen Esther": Haman is the ambitious and petty advisor of King Ahasuerus who manipulates the king into banishing his wife. Leading the search for candidates for new royal wife, Haman developed a hatred for the Jew Mordecai after the latter refuses to bow to him. Haman manipulates the king into passing a law by which all Jews in the empire are to be eradicated, while also trying to speed up Mordecai's execution.

    H – Q 
  • Hero: 108: Twin Masters is a malevolent entity who wishes to plunge the Hidden Kingdom into everlasting chaos. Originally a prince with aspirations of conquest, Twin Masters had since become a master of chaos energy, altering their plans to decimate the Hidden Kingdom and lord over the remains as a despot. Several of Twin Masters's plans are designed to cause massive damage, including forcing Oyster-Rahmas into draining the oceans; trying to revert all life to its prehistoric state; changing the course of an asteroid to crash into Hidden Kingdom; creating a chaotic storm with Mighty Ray's eyes; and, in the finale, absorbing all life energy into themselves as well as condemning their former minions to die alongside Hidden Kingdom. Forming a deep hatred for First Squad — Lin Chung in particular — Twin Masters corrupts Commander ApeTrully with their chaos energy and forces him to attack First Squad against his will. Drunk on their love for carnage and destruction, Twin Masters darkened the setting of an otherwise lighthearted show with their presence.
  • High Guardian Spice's "Attack on High Guardian Academy": Mandrake is an unhinged shapeshifter who revels in wanton destruction and death. After Olive fails in her mission to kill Rosemary and her three friends, Mandrake is appointed to take care of the girls for her. Posing as a teacher within High Guardian Academy, Mandrake drugs the other teachers and lures most of the academy's students into a locked room and sets it and the rest of the school on fire, nearly burning all the students and teachers alive. Once he finally confronts Rosemary and her companions, Mandrake almost kills the four of them, and even targets Olive once she turns against him.
  • Hot Wheels: Battle Force 5 Season 2: Krytus was known as the most malicious being in the multiverse. Ambitious and power-hungry, he restarted an eons old war between the Red and Blue Sentients to conquer the multiverse. When his own twin sister, Sage, froze the Red Sentients in stasis, he retaliated by carrying out a genocide on the Blues. It was also revealed that he had several thousand Blue Sentients tortured to death, and the one who managed to enter hibernation to escape him was punished by having his body sabotaged, dooming him when he woke up. After being freed from his prison, he then throws the one who released him off a cliff. He then spends most of the series trying to kill Sage. After being forced into an Enemy Mine with Vert to escape the Shadow Zone, he sets up an ambush for Vert the moment they're out of it. Not even the other villains are safe from his wrath, as he starts an Enemy Civil War among the Vandals through Grimian. In the season finale, when he and Sage finally have a confrontation, he asks Sage if it was worth it to imprison the Red Sentients, in which she replies that if she hadn't, Krytus would've endangered not only the Blue Sentients, but the multiverse. Krytus actually agrees with her as he plans on using them as an army to conquer the Multiverse itself and cares nothing for them.
  • Huntik: Secrets & Seekers: The Betrayer, originally one of the sorcerers and seekers who helped found the Huntik Foundation, turned upon his fellows to summon the Lovecraftians monstrosities known as the Nullifers to destroy the world. The Casterwill family fought back and destroyed the Betrayer, but his spirit endured, forming the Bloodspiral Brotherhood to work at his revival. The Betrayer eventually had the Casterwill family "purged" with any who served as obstacles treated the same way. Upon his revival, the Betrayer revealed that he had double-crossed the Bloodspiral Brotherhood and they would not be spared from destruction either. The Betrayer proceeds to summon a comet the destroy everyone present and summon the Nullifers, plotting to destroy everything that lives on Earth to satisfy his lust for chaos.
  • Inhumanoids:
    • Metlar is the tyrannical leader of the Inhumanoids. The former slave of Sslither, Metlar overthrows and imprisons his former master before waging a genocidal war against the Mutores to Take Over the World. Awakened from his seal eons later, Metlar launches an all-out attack on Earth with his fellow Inhumanoids, razing a Soviet weapons department to a smoldering heap and stealing several cluster missiles while having his servants attack and destroy all they can. Metlar's ultimate goal is to use the missiles to obliterate the crust of the Earth and drown the entire world in fire, killing everything—his own loyal servants not excluded — so he can rule over the ashes that remain. Throughout the rest of the series, Metlar brutalizes and threatens to torture his own minions for every slight and attempts to destroy everything he can get his fiery talons on.
    • D'Compose, Metlar's terrifying second-in-command, is a hulking, undead monstrosity who pulled an entire city underground to turn it into his personal domain, killing everyone who lived there and reducing the city's knights into his undead slaves, cursed to wander the ruins of the town forevermore. Able to painfully transform anyone he touches into his undead slaves, D'Compose demonstrates his powers on the noble scientist Sandra Shore and tries to use her to kill her own friends, eagerly decomposing anyone he can whilst aiding Metlar in his conquest. D'Compose's vilest actions come when he has Blackthorne Shore amass countless disaffected teenagers into a cult in his name, reducing them all to his decomposed slaves and having them attack the nearby city, proclaiming his intention to shroud the world in darkness and turn all that lives into the undead.
    • Blackthorne Shore is a wealthy industrialist who came across the secrets of the Inhumanoids. Blackthorne attempts to free them to use them to take control of the world, allowing them to first wreak death and destruction at their whim. When his own sister Sandra is turned into an undead monster by D'Compose, Blackthorne acts horrified — but then abandons the heroes to die when they try to save her so he can take control of Metlar, settling for allying with him to present him with a way to destroy most of the world so Blackthorne can rule over the remainder. After being foiled, Blackthorne eventually starts a Cult with D'Compose, convincing numerous young men and women to submit themselves to the evil Inhumanoid to be changed into his undead slaves. Blackthorne continues to try to control the Inhumanoids and kill the heroes in his quest to dominate the world, fully admitting that he himself is an utterly evil, monstrous human being as wicked as any Inhumanoid.
  • Invasion America: The Dragit is the military commander of Tyrus and the Evil Uncle of the planet's ruler Cale-Oosha. When he makes an attempt to overthrow Cale, Cale manages to escape, ending up on Earth where he fathers a son named David. Upon learning of them, the Dragit attempts to murder the baby and his mother. Installing a secret base on the moon, the Dragit reveals his plan to use a weapon to have asteroids bombard America, causing countless deaths, until the country gives in whereupon the Dragit will continue the process with every nation on Earth, killing millions until the human race gives in. When David is captured in the finale, the Dragit opts to personally attempt to murder his great-nephew, his rhetoric about saving Tyrus a front for his own cruelty and lust for power.
  • Jackie Chan Adventures' "Into the Mouth of Evil": Mr. Jumba is a museum curator who plots with his associates, Portia Martindale and Dr. Weber, to destroy the Ganges River to excavate the treasures therein. "Accidentally" injuring Jackie's tooth, Jumba cons him into an appointment with Weber, who inserts a tiny magical artifact, the Sutras of Raktajiba, into Jackie's filling. Arranging for Jackie to unwittingly smuggle the Sutras into India, Jumba then has Weber painfully extract them and reveals his plan to use them to dry up the Ganges with their power. When Jackie informs them that this would result in drought and famine for millions, the three villains simply mock him for being "sentimental" before trying to kill him and his niece Jade.
  • Jayce and the Wheeled Warriors:
    • Saw Boss leads the Mind Monsters, who were created by Jayce's father, Audric, initially for a peaceful purpose before rebelling against him in order to conquer the galaxy. A bellicose commander, Saw Boss orders the invasion of many planets destroying several of their ecosystems; institutes mass enslavement; causes the starvation of worlds' worth of people; creates horrific plant creatures in order to enrage a warlord and steal his weapons after he and his armies are defeated; and manipulates the population of another into a civil war for his own gain. As resistance groups rise up against him, Saw Boss infects their water supply in order to weaken them. His thirst for power knowing no limits, Saw Boss even used slave labor, capturing innocent scientists to build a weapon to allow him to conquer other universes and, when stopped sabotaged a satellite to make it crash into a planet out of spite. In order to get the ultimate weapon Jayce possessed and get rid of him and his companions, the Lightning League, Saw Boss manipulates several people to do his bidding while betraying them once they're no further use to him. He even creates a black hole by crashing three planets; destabilizing another inhabited planet; and crystallizing another one, including its population, all just to get what he wants.
    • Vantu is a slimy magician who betrayed his own race by stealing the Liberty Stone that protects his race for years, before allying himself with Saw Boss in order to defeat the Lightning League. Disguising himself as the former leader of his race, he tricks one of the Lightning League members, turning him into stone, and after Jayce saved him, Vantu went into the nearby village and petrified most of the population with his Liberty Stone. Returning in the next episodes, he aids Saw Boss by causing much mayhem, with his worst act being his attempt to drain the core of a certain planet in order to boost his magical power — with no intention of sharing with Saw Boss — which would result in the annihilation of all life in the planet. In his final appearance, he made a magic generator that resulted in the fabric of the universe getting torn apart so that he could give Saw Boss more power.
  • Jonny Quest franchise:
    • The New Adventures's "Temple of Gloom": The wicked Deprave is from a nation bordering two countries formerly in peace talks. Kidnapping Hadji's kindly mentor, Deprave subjects him to painful mental control to use his powers to sabotage the peace talks, with her intention being to force both nations to go to war and completely obliterate one another so she may preside over attempts to pick up the pieces.
    • The Real Adventures:
      • "AMOK": James Compton is a former special forces operative thought killed in action but now working as a freelance mercenary for whoever can hire him. Paid by a private party to investigate a hindrance to the drug trade in Borneo, Compton assumes the identity of "Mitchell Stramm" after his party is seemingly wiped out by the native Amok monster, winning his way into the Quest's family's good graces and finding the village that's been disrupting the drug trade. Smugly betraying the Quests at this point, Compton opts to simply massacre every last native man, woman, and child in the village to remove them as an obstacle, gloating that his employers will pay him handsomely for each head he brings back to them, attached to the bodies or not.
      • "Rock of Rages" & "General Winter": General Vostok is a frozen-cold ex-KGB terrorist who yearns for a world "free of having to make decisions." Vostok introduces himself icily murdering two treasure hunters to procure a destructive golem with which he attempts to assassinate the President of the Czech Republic, and later attempts to create a flash-freezing superweapon he first tests by flash-freezing a base full of soldiers to death. Vostok strong-arms a scientist friend of Dr. Benton Quest into perfecting the device, and when the scientist chafes, Vostok shoots him dead in front of Quest to hurt him. Vostok appears one last time in the comics where he attempts to convert a nuclear reactor into the world's most potent nuclear weapon, one he spitefully attempts to set off when foiled heedless of all the lives — all of his own men included — he'll waste in the process.
      • "Nuclear Netherworld": Von Romme is a Corrupt Corporate Executive extraordinaire who built his company over a uranium mine. Von Romme abuses his own minions; looks the other way when his uranium irradiates the water supply of the local Hopi population; and when a local farmer tries to expose him, Von Romme has him murdered and his death made to look like an accident. Von Romme's true evil comes to light when it's revealed he's selling the uranium to terrorists for them to make nuclear weapons with, as Von Romme stays ambivalent as to whomever gets nuked so long as his bank stays intact.
      • "Eclipse": The succubus/vampire known as Elise Lenoir initially appears to be a victim, an innocent young woman on the run from evil men. However, Elise was actually maintaining her youth and beauty by draining the life from beautiful, innocent women, and the man hunting her was trying to avenge his sister when she fell victim to her. Elise murdered the men who tried to tail her, and later mind controlled Hadji into her slave to bring Jessie to her for her food source. When her right-hand man protested about Elise trying to replace him with Hadji, Elise declared he was right and sucked the life from him as well. When her deadline of an eclipse was approaching, Elise abandoned all pretense of charm and subtlety and assumed her monstrous true form to kill everyone around and drain Jessie's life.
      • "Diamonds and Jade": Dja'Lang Mukharno is a puppeteer and brother of Kumar who exploits his people's old traditions for personal benefit. Coaxing his weak-willed brother into routinely selling off a rare gem to greedy buyers, Dja'Lang summons a shadow demon to brutally kill the buyers and anyone else in the premises to keep the money and the gem. Dja'Lang attempts to kill the Quest family and their friend Jade alongside the cops in the area when Jade sets Kumar up, and when Kumar loses the gem to the Quest family, Dja'Lang turns the shadow beast on him with full intent to murder him for his failure, laughing that he should have killed him years ago.
  • Kipo and the Age of Wonderbeasts: Dr. Emilia is the finest and most steadfast proponent of Fantastic Racism in a series that otherwise emphasizes the importance of reaching out to people. Years ago, Emilia murdered her own brother Liam for reaching out to the surface-dwelling Mutes and used his death as an act of propaganda to further her eventual designs of Mute eradication. Emilia helped shape the misanthropic views of Scarlemagne with her cruel experiments on him when he was still Hugo, and used her former colleague Song as a brainwashed weapon for years on end after Song became a Mega Mute, kicking off the series by coldly ordering Song to murder her own child Kipo and devastate her people's burrow in the process. In Season 3, Dr. Emilia invents a cure that forces a permanent Death of Personality on the uplifted Mutes, using it to devastating effect on several of Kipo's allies as well as the remaining members of Wolf's old Mute family. Emilia consistently rejects and suppresses every single attempt to better herself to the end of the series, attempting to kill human and Mute alike when the two sides reconcile and trying to kill Kipo after the latter saves Emilia from a Fate Worse than Death.
  • Kulipari: An Army of Frogs:
    • Lord Marmoo, the brutal Evil Overlord of the scorpions, believes that the weak have no right to survive. Longing to destroy the fertile Amphibilands, Marmoo teams up with the Spider Queen Jarrah and leads the armies into battle, killing the Turtle King Sergu. Upon his initial defeat, Jarrah makes Marmoo stronger than before, whereupon he repays her by murdering her. Drunk on his newfound might, Marmoo attacks another village to raze it to the ground and kills the chief of the frogs himself. Returning to the spiders, Marmoo kills many of them by collapsing their fortress, not even caring his own men and brother Pigo are within. Forcing the surviving spiders into service, Marmoo attacks the Amphibilands, killing many frogs and even sneering that the only scorpions to die are those too weak to survive. Upon his victory, Marmoo banishes the frogs into the desert with no supplies, condemning them to slow death by heat and starvation. Not even his men are immune to his cruelty, as any scorpion injured in the fight, including Pigo, is given the choice of leaving or being eaten alive. Ambitious, brutal, cruel and egotistical a monster as they come, Marmoo believes only in power, domination and revenge with nothing to stand in his way.
    • Dream Walker: Lord Darkan, the ruler of Cardigal, is a vicious lizard who relishes in dominating those in and around his city. With an army of lizards and spiders at his command, Darkan and his forces seek out strong warriors around the world, kidnapping and imprisoning them before forcing them to fight in the Kingdom of Fighters tournaments. Those who refuse to fight are either killed or cajoled into fighting after Darkan threatens to murder their families. When Darkan learns that Koa is a Dream Walker with extraordinary power, he and his army storm Koa's village and force his father to deliver Koa into his custody. After Koa initially refuses to join the Kingdom of Fighters tournament and threatens to kill Darkan, Darkan convinces him to fight by smugly telling Koa that should anything happen to him, his soldiers will slaughter all of the prisoners in Cardigal as well as Koa's entire village.
  • Kung Fu Panda:
    • Legends of Awesomeness:
      • "Enter the Dragon": Ke-Pa is an ancient demon who terrorized the Valley of Peace with his army of demons, driving out or killing the citizens. After his army was sealed away by Oogway, Ke-Pa spent decades waiting for the peach tree that his powers are bound by dies, then, with his power returned, transformed into a dragon and lay siege to the Valley of Peace, threatening to eat the citizens one by one. Capturing and torturing Shifu under the belief that he has the Hero's Chi, Ke-Pa tries to crush the Hero's Chi out of him to free his demon army, before doing the same to Po and succeeding. Once his demons are unleashed, Ke-Pa orders them to kill everything in the Valley of Peace, bragging that he will destroy all mortals on the planet and reign supreme.
      • "A Tigress Tale": Mugan is a skilled kung fu master whose twisted ideals of seeking "perfection" in her students instead hide an utter sadist. Mugan takes in kung fu masters and leads them on that she'll teach them her art, but instead she is lying and subjects them to horrific training in an attempt to break them. Mugan slowly breaks her students both physically and mentally, like Wu Yong, and then leaves them broken slaves who are added as her servants. When Tigress joins her training, Mugan tries to enslave her to the academy and promises that she will be broken.
    • The Paws of Destiny:
      • First half: Jindiao was the original Dragon Warrior until his hunger for power corrupted him and drove him to kill his four students, the Four Constellations, in his attempt to become a god. His spirit kicked out of his body, Jindiao possessed a vulture and survived by drinking the chi of "lesser beings" for 1,000 years. Jindiao seeks once again to "enslave the world in fire and fury", regularly attempting to Mind Rape, corrupt, or kill Po and his four young students, the new Four Constellations, and eventually attempts to wipe out all of Panda Village and everyone in it out of spite. At one point one of their allies, Bunnidharma, takes a lethal blow meant for Po and dies in his arms—upon which Jindiao laughs in his face. A dreadful boss as well, Jindiao kills, beats and throws his minions to the wolves with aplomb. Even his most treasured student Jade Tusk, whom Jindiao mentored for years, is thrown away almost unthinkingly by him when one of the heroes tries to use her as a hostage.
      • Second half: The Voice in the Shadows, aka Baigujing, aka the White Bone Demon, once roamed the land devouring souls of entire villages and leaving dolls behind to mark her crimes. When sealed away by Sun Wukong, the White Bone Demon eventually contacts Shi Long, corrupting the young girl into being her slave and using her to assassinate the Emperor, Shi Long's own adoptive father. Having Shi Long steal the Wellspring for her, the White Bone Demon's plans lead to a drought plaguing China, and Shi Long destroys entire villages to serve the White Bone Demon. The White Bone Demon's spirit inhabits a Humongous Mecha with Shi Long's help in the finale, betraying Shi Long and eating her alive before viciously trying to kill Po, his students the Four Constellations, and all of their friends before bringing an age of darkness onto China.
    • The Dragon Knight's "A Thread in the Dark": The High Priestess runs a small village in the outskirts, where she ostensibly helps travelers. In truth a cruel cannibal, the High Priestess runs a cult where innocents are taken to be harvested, murdered, and cannibalized by her and her followers, something she has done many times. Upon Veruca trying to save her brother Klaus with her sorcery, the High Priestess reveals she doesn't even believe in her own purported religion, murdering people for the sheer enjoyment.
  • The Last Kids on Earth:
  • The Legend of Calamity Jane:
    • Bill Doolin is a dirty little bandit out to make a big score. Disguising himself and his men as Comanche, he rides into one town, shooting it up and beating the sheriff to near-death in order to frame the peaceful tribe to provoke a war between them and the US military so he can steal a supply of gold. Later freed from jail, Doolin steals a train carrying explosives so he can use them for his scores, heedless of the lives lost, and when Jane faces him, Doolin even tries to kill her beloved horse just to hurt her more before he kills her.
    • "Troubled Waters": Mr. Filbert is an arrogant, racist bureaucrat in the pocket of his greedy higher-ups. He proves himself far worse than most disposable bureaucrats by muscling onto Apache territory while trying to use outdated legal tactics to force them off. When intimidation fails, Filbert forces Sheriff O'Rourke to push them off and shoot any who resist, eventually revealing his plans to murder their leader to spur them into war and massacre them all to the last, even trying to burn Jane and O'Rourke to death for getting in his way.
  • The Legend of Prince Valiant:
    • "The Walls of Tyranny": Baron Frederick von Holsing manages to outdo even recurring villains with his greed and lack of regard for human life. Von Holsing is a noble in the kingdom of Kengary, which has been at war with a neighboring nation for as long as anyone can remember. When King Ian, Frederick's uncle, makes inroads to initiate a lasting peace, Frederick murders him to frame their enemies and keep the war going. It is revealed that Frederick intends to prolong the war indefinitely so he can take men, women and children as slaves to work to death in his private mines for his personal profit. When Valiant uncovers the plot, Frederick attempts to murder his friends, send Valiant to his mines and kidnap Valiant's female comrade Rowanne with the threat of making her his. Vain, selfish and greedy, Frederick von Holsing stands as the worst representative of nobility in all the series.
    • "The Sage" & "The Rings of Truth": Sage Advisor Selena is the Treacherous Advisor to King Michael of the North. She engineers a civil war, which causes the deaths of several hundred people, to arrange a better puppet figurehead to become king. She also conspires to murder an infant, frames Rowanne for a crime which makes her leave Camelot in disgrace, and turns an invention of peace into a war weapon in an attempt to frame Merlin for a crime. Vain, with no loyalties to anyone but herself, Selena surpassed the Mordred in terms of monstrosity.
  • Legend Quest:
    • Season 1:
      • Quetzalcoatl is the reincarnation of a long line of other Quetzalcoatls. The others were arguably well-intentioned, and would destroy humanity every 10,000 years and remake it at the cost of his own life with the intention of bettering humanity. This one's methods, however, were deemed too cruel, and he was locked away. The current Quetzalcoatl, feeling "bitter" and "betrayed" by serving a race of "ants", spent the last 10,000 years plotting to Kill All Humanspermanently — and remake the world in his own image. First, he spread the legend that destroying the Esfera egg using the Celestial Point would destroy him, in an attempt to have the new Quetzalcoatl killed so his existence won't be averted. He enslaved the witches and unleashed his Horrorosos on Puebla, turning it into a Zombie Apocalypse. He also opens a portal into the mortal realm in an attempt to destroy the world. When Leo and his crew thwart him, he pulls the town into his dimension and enslaves everyone in it — sans Marcella, Godofredo and Rosa — turning them into beasts under his command. He also tortures Marcella, threatening to take her soul out in front of Leo. Eventually pulling the entire world into his dimension he goes to war with the Brotherhood, killing a large number of them. He kills Nu Gui, and rips Leo's soul out of his body and takes control of his lifeless body in an attempt to destroy the Esfera.
      • "Ghost Of Medusa": Medusa is a Gorgon from Pompeii who lived in the cave of Mount Vesuvius, and had the unique ability to turn anyone who gazed into her eyes into stone. She had used this power to turn several humans into stone, until one day a man named Perseus turned her into stone and killed her. Upon becoming a ghost, she gained the power to turn other ghosts into stone. She had turned many warriors who tried to defeat her into stone. She eventually made a deal with the Mayor that if they provide her a sacrifice every year she will spare the town. After being disturbed by an unwitting Leo, she reneges and turns the ghost of the townsfolk into stone, where they will crumble into dust once the sun rises. When Leo and Teodora stumble into her cave they find the skull of someone Medusa slayed; she also tries to kill them by lowering them into a pool of lava.
      • "Vodnik": The Vodnik was a human tinkerer who intended to use his inventions to help others, however growing fed up with the impurities of his fellow adults, he turned himself into a frog monster, and became a collector of souls. He would kidnap any children who went by a lakes or even the smallest puddles, pull them underwater, suck their souls out and put them in cups or jars. He has been doing this for decades, possibly centuries, and has acquired a collection large enough to fit three whole shelves, each with over 20 souls. When Alebrije goes in search of the Grimsword Root, the Vodnik kidnaps him and sucks his soul out, and attempts to do the same to Leo. Despite his claims of wanting to save children from corruption, The Vodnik was every bit as corrupted as the worst adults himself.
    • Season 2 (Masters of Myth):
      • Coyolxāuhqui, Goddess of the Moon, is the firstborn of Goddess Cōātlīcue and former ruler of the skies. After the birth of her brother Huitzilopochtli the Sun God, Coyolxāuhqui attempts to kill her mother in retaliation, only to be stopped by her brother. Coyolxāuhqui waged eternal war with Huitzilopochtli before being turned into a statue. Contacting Brother Upton, Coyolxāuhqui has him work to release her by any means necessary. After being freed, Coyolxāuhqui plots to incubate in the center of the Earth, eventually blowing up the planet and gaining enough power to take revenge on her brother.
      • Brother Upton was once just a normal member of the Brotherhood who researched Coyolxāuhqui. Coming to worship her, he was laughed of before making contact with Coyolxāuhqui and becoming her herald. Upton turns the Brotherhood into an Apocalypse Cult dedicated to freeing Coyolxāuhqui, having countless magical creatures captured in order to use their energy to break the seal. After Father Godofredo gets suspicious of his intentions, Upton attempts to have him killed. Realising Leo and his team are on the trail of the truth, Upton has Tsukumogami released at them, uncaring about members of the Brotherhood caught in the danger. Manipulating Marcella and her team into capturing the last creature he needs, Upton uses her as the conduit for freeing Coyolxāuhqui, nearly killing Marcella in the process. With his Goddess free, Upton plans to use his newly bestowed powers to kill the heroes before helping Coyolxāuhqui end the world.
  • The Long Long Holiday: Durand is a resident of the small French town of Grangeville. After the town is occupied by the Nazis, Durand becomes a traitorous collaborator. Durand vows to root out Jews and French citizens who are disloyal to the Vichy regime. When a group of children who name themselves the Robinsons start to resist the Nazis, Durand tries to expose them and have them arrested by the Nazis. Durand manages to get their teacher Mr. Herbin arrested. Durand turns in a Jewish teenager who refuses to wear the Star of David badge to the Nazis and is thus sent to a death camp. Durand ultimately finds the Robinsons' clubhouse in the woods and informs the Nazis of it, happy that the Nazis intend to kill everyone there.
  • Love, Death & Robots's "Good Hunting": The Governor is a vile politician with a penchant for machines. Unable to become aroused by regular human beings, the Governor decided to drug and capture Yan. Afterwards, he had several surgeons operate on Yan, cutting her body to pieces all while she was still conscious. Once all of Yan's flesh was gone, the Governor had his surgeons turn her into an android, and promptly used Yan as his personal Sex Slave.
  • Martin Mystery's "They Came from the Gateway" two-parter: In a series filled with supernatural beings and monsters that have some semblance of redeeming traits, the ghostly Gatekeeper is wholly bereft of them. Keeper of the gateway to the underworld and longing to take over the human world, the Gatekeeper violently turns the head of the Center, M.O.M., into his slave and proxy while sending out monsters to kill her young agent. Hungering to “feast on the bones” of anyone who opposes him, the Gatekeeper's ultimate goal is to swarm the entire world with monsters from the underworld and rein in the bloody slaughter of mankind, even managing to unleash his monsters on several populated cities throughout the planet to wreak wanton havoc before he's ultimately stopped.
  • Matt Hatter Chronicles:
    • Lord Tenoroc is the master of all the villains within The Multiverse, and the Arch-Enemy of the Hatter Family. Tenoroc is responsible for turning Discordia into a lifeless wasteland, and for removing all power of Carnival City which forced the children to rely on packs to survive. Tenoroc once tried to destroy the multiverse in the past so he could remake it in his image, until being trapped in an unknown dimension by Alfred Hatter. Tenoroc uses the Triple Sphere to summon villains to wreak havoc across the multiverse: he tries to eradicate the denizens within the Region of Ruin; tries to starve the population of the Sea of Sands to submission by removing their water supplies; and tries to bring the complete destruction of the multiverse, such as when he tries to turn it into a desert wasteland or pollute the air with toxic gas so everyone could suffocate. Tenoroc also shows no care for his minions, knowingly sending one to their deaths if it suits his needs. Tenoroc would later try to drown all of Carnival City and its denizens, and ultimately, tries to kill the mystical Amber Crest Dragon to destroy the Enchanted Forest and all the creatures within.
    • "Monster From The Dark Lagoon": Phibious is a monstrous fish creature from the black lagoon summoned by Lord Tenoroc to pollute the sewers of Carnival City. However, Phibious has his own plans and decided to poison the air of the city with swamp gas so that everyone could perish. Phibious plans to kidnap one of Matt's friends and two street kids, so he can genetically modify them into monstrous fish creatures like himself and have them serve him as slaves forever.
    • "Heart of a Vampire" & "The Root of All Evil": Count Venom, the "Prince of Darkness", is a vampire seeking to usurp Lord Tenoroc and conquer the multiverse for himself. Sent by Tenoroc to turn Matt Hatter into his eternal slave, Venom has turned Roxie into a vampire slave to attack her friends, only to be defeated. Returning after his Sanctuary Chamber Heart was restored, Venom kidnaps Roxie to turn her into a Living Battery and drain her life force; doing so would poison all of the Enchanted Forest, which he plans to remold into a dark realm for him to rule over. Venom then starts turning several inhabitants of the realm into bloodsucking vampires to serve him.
  • Maya and the Three:
    • Lord Mictlan is the bloodthirsty god of war hellbent on destroying humanity. Initially wanting to kill a newborn Maya for being the product of his wife Lady Micte's infidelity, Mictlan only spares her so he may sacrifice her when she's older in order to gain immense power. Come present day, Mictlan personally slaughters the Teca army and sends several gods to bring Maya to be sacrificed, gleefully mutilating and killing those who fail or oppose him. Despite claiming to love Micte, come the final battle, Mictlan ignores his wife's pleas to abandon his plans to destroy humanity and furiously attacks her. When the heroes start to gain the upper hand against him and his army, Mictlan kills his loyal underlings and devours their hearts in order to strengthen himself.
    • Xtabay, the Goddesss of Illusion, is one of Lord Mictlan's underlings, and his most sadistic. Xtabay invades Picchu's village, having her army slaughter everyone in his village and murdering Picchu's parents. Xtabay allows Picchu to live solely for him to live with the fact he condemned his people to be massacred and fall into despair. Participating in Mictlan's campaign to destroy humanity, Xtabay returns to haunt Picchu by psychologically torment him with illusions of her murdering his parents and his failure to protect his people. In the show's finale, Xtabay helps Mictlan's attempt to destroy all four kingdoms, starting with Teca.
  • Men in Black: The Series:
    • Alpha was once the top agent for the Men in Black; however, after getting his hands on an alien device known as the Cosmic Integrator, he began his path of evil that leads him to become the monster he is in the present. Originally offering his partner, Agent Kay, a team up to use the Cosmic Integrator for immoral schemes, Alpha coldly gunned down his pupil when he refused Alpha's offer. Alpha went on to butcher aliens across the galaxy, ripping off or tearing out parts of their bodies that he would then fuse to his own biology via the Cosmic Integrator, with his most targeted part being the heads of aliens, attaching them to his torso while they stay conscious of their current state but unable to do anything of consequence to help themselves. Throughout the series, Alpha regularly mutilates aliens, nearly kills Agent Kay and his partner Jay in various sadistic ways, and murdered at least one human to steal his body parts. Trying numerous times to subjugate the Earth by way of mass murder, from using a Kill Sat to trying to flood half the planet, Alpha ultimately allies with the psychopathic Vangus to lead a full-scale assault on Earth, laying siege to numerous cities and causing countless amounts of destruction, all in his quest for total domination of first his own planet, then the galaxy. A sociopath with a lust for power above all else, Alpha was an arrogant, manipulative genius who used his intelligence for nothing but his own gain.
    • Vangus is the leader of the Ixion Federation, a race of planet-plundering aliens who value oil as an extremely valuable commodity and go from planet to planet draining them dry of their oil. Vangus sets his eyes on Earth and strikes up a deal with the traitorous MIB agent Alpha to invade Earth and steal it of its oil, leaving what remains of the Earth itself for Alpha to dictate. Vangus grows tired of waiting after Alpha postpones the invasion and, after a failed attempt to scout out oil fields which leads to his capture, Vangus breaks out in the series finale and teams up with Alpha to invade the Earth. Vangus sets his forces to obliterate both the UN and the Washington Monument before leading his forces in an all-out invasion on Earth, ravaging cities all across the world. Out of sheer impatience with the continued resistance, Vangus ultimately attempts to detonate a bomb to wipe out all life on Earth to make the planet's oil ooze to the crust, callously betraying Alpha and setting a torpedo en route to Earth with the assurance he'll come back and clean up whatever's left after the attack.
  • Metalocalypse: Mister Salacia is the puppetmaster behind the Tribunal monitoring Dethklok. At first seeming to be simply an influential human power broker, Salacia reveals himself to be far more when he uses telekinesis to gruesomely massacre a group of subordinates for acting without sanction, and later takes over the mind of military general Crozier to reroute US Army resources to the mysterious Falconback Project. In the finale, Salacia is revealed as an Eldritch Abomination from another dimension who lost most of his power upon getting trapped on Earth in ancient times, and has manipulated influential people throughout history to regain his full strength. His goal is to bring the Doomstar to Earth and perform a ritual to transform it into a portal to his home dimension—and Salacia cares absolutely nothing for the fact that doing so will render the Earth a lifeless husk due to the star's extreme heat. When Dethklok finally confronts him face to face, Salacia reveals that once he's done draining their mystical energies to power the Falconback device for the ritual, he plans on killing all of them except frontman Nathan Explosion, whom he intends to keep as his immortal, tortured plaything for all eternity.
  • Mighty Orbots: The massive bio-computer Umbra is the leader of SHADOW, an intergalactic terrorist organization dedicated to universal conquest and the dissolution of the United Planets. Umbra's schemes include attempting to ravage the Earth with monsters and an asteroid; framing the Orbots for terrorist attacks in order to get them thrown into a Hellhole Prison secretly run by SHADOW; bombing and nearly overtaking the United Planets headquarters; and enslaving a peaceful race of primitives whose planet he spitefully tries to blow up when they are freed from his control by the Orbots. When a minion successfully completes his assigned mission, Umbra informs him that he is abandoning him to die due to no longer having any use for him, and when a scientist later complains that Umbra is treating him more like a servant than a partner, Umbra responds by infecting the doctor with his own deadly plague. In the series finale, Umbra wipes out an entire solar system with a weapon called the Sun Smasher, which he threatens to use on the Milky Way unless he is declared overlord of Earth. When the Orbots launch a desperate direct assault against him, Umbra captures them and tortures them with nightmarish illusions while smugly informing them that soon everyone they know and love will be either under his control or obliterated.
  • Monster Force:
    • Count Dracul(a) himself is the Big Bad of this series, having enslaved countless to his vampiric curse in his constant efforts to pursue power and see Dr. Reed and his Monster Force exterminated. Dracula tries various schemes throughout the series, from trying to trap a member of the Monster Force in his lycanthropic form, to have him kill his own friends, to trying to trick a large group of vampires into performing a ceremony that would allow Dracula to take their power and become a god, killing all of them in the process. In his nastiest appearance, Dracula murders the real Abraham Stoker to take his appearance to trick Reed, forcing him to listen as the rest of Monster Force is seemingly killed — only to reveal he's intending to make them his vampire slaves to have Reed die at their hands, admitting the whole plot was solely to make Reed suffer. An elegantly vicious creature of the night all the while, Dracula consciously rejects his own humanity to see all before him destroyed in the finale.
    • "Dark City" The Dark Town is a living and malevolent entity that takes the shape of a town to lure in prey, while it sadistically relishes in their fear as it drains their lives and souls, the fate that befalls two luckless travelers in the opening. The Dark Town has been traveling for centuries, depopulating entire towns that it lures into its borders before devouring them, vanishing to repeat the cycle anew before trapping the Monster Force themselves.
  • Moral Orel: Cecil Creepler was the local ice cream man of Moralton who was in truth immensely depraved. After failing to lure 12-year-old Doughy Latchkey into the back of his van, Creepler became a prolific Serial Rapist who targeted dark-haired women. Assaulting seven women, Creepler's last victim was schoolteacher Miss Agnes Sculptham when she dyed her hair black to compel him into entering her apartment. Despite his death, Miss Agnes suffers a psychological breakdown upon hearing the news, making it self-evident how broken she had become because of his actions.
  • Moville Mysteries's "The Day Rico Became Smart": The avaricious Professor Kindly has taken to eliminating his rivals so that he can steal and profit from their ideas. Finding his targets through papers that have been submitted for peer review, Kindly lures the victims to his lair, where he cuts their brains out while they are fully conscious and aware, at one point informing a would-be victim, "Now then, this won't hurt a bit...it'll hurt a lot!" After extracting information from the excised brains, Kindly keeps them as souvenirs, preserving them in jars that adorn his mantel. When Rico Caliente, a jock who gained Sudden Intelligence from a concussion, loses his newfound intellect and escapes Kindly's clutches before his knowledge can be harvested, Kindly sees it as no big loss, since no one will believe what the boy has to say, and he still has Rico's stolen cold fusion thesis to claim as his own and get rich off of. A greedy, sadistic Serial Killer, the professor stands out as the show's starkest example of Humans Are the Real Monsters, as his episode is the only one without any paranormal elements.
  • My Dad the Bounty Hunter: Pam is the new representative of the Endless Horizons Conglomerate tasked with gaining control over Doloraam's kaletite. Despite her pleasant demeanor, Pam truly loathes having to negotiate with a "backwater planet" like Doloraam and would much rather take their kaletite by force. After Empress Gurira declines the Conglomerate's offer, Pam gleefully gives the order to destroy Doloraam, having her troops murder numerous citizens as they steal the kaletite. When her abused second-in-command, Beta, refuses to kill Shaun under her orders, Pam takes manual control of her, alongside the other shock troops, and nearly kills Shaun, and later, Lisa, herself. When Tess foils her plans, Pam takes sadistic pleasure in trying to kill her; happily admitting that the Conglomerate doesn't even need kaletite to prosper and that she's motivated solely by greed.
  • The Mysterious Cities of Gold:
    • Conquistador Francisco Pizarro is the conqueror of the Incan Empire and a cruel, greedy man out for his own enrichment. Seeking the Cities of Gold, Pizarro tries to have entire villages razed and to kill or enslave young Esteban and his friends. Taking over the Incas, Pizarro forces them into slavery and massacres a great deal of them, wiping out their empire to establish control. Ostensibly loyal to the Spanish crown, Pizarro's only true loyalty is to himself and his insatiable greed.
    • King Menator is the cruel ruler of the Olmecs, an underground race seeking immortality. Tyrannizing many of the local tribes, Menator kills and harvests countless innocents for their skin cells to rejuvenate himself and the Olmecs, trying to have Esteban and his friends subject to the same fate and ordering an entire village massacred when they escape into its borders. Menator seeks the Cities of Gold for its priceless technology, using his flying weapon to vaporize many of the Mayans—-whom he regards as utterly inferior-—when they rise up against him, and even horribly beating the young Tao against a cliff side with the threat of killing him if he's not allowed access to the Cities of Gold. Though preaching everything he does is for the benefit of his race, Menator only intends to preserve those "worthy" while dismissing the lives of the rest and even his own loyal soldiers, intent only on taking what he can and killing everyone else in his way.
  • Mythic Warriors: Guardians of the Legend's "Icarus and Daedalus" & "Theseus and the Minotaur": King Minos is the tyrannical ruler of Crete. Minos asks Daedalus to build him weapons, claiming he will only use them to defend his kingdom. After the Athenian fleet arrived following his call for peace negotiations, Minos has Daedalus's weapons, including a giant robot named Talos, unleashed on them, resulting in the destruction of the whole fleet. Those who survived are locked in the Labyrinth, an inescapable prison built by Daedalus which houses a man-eating Minotaur. Minos reveals to Daedalus that as the price for their defeat in the war, every year the Athenians must send seven sons and seven daughters to be sacrificed to the Minotaur or Athens will be destroyed. When Daedalus refuses to make any more weapons, Minos imprisons Daedalus and his son, Icarus, with the only way out being through the Labyrinth. Upon learning of the two escaping with man-made wings, Minos orders his men to shoot them down. After the last batch of Athenians arrive, Minos has them them taken to an arena to face his bulls unarmed, with those lucky enough to survive being sent to the Labyrinth. Following the Minotaur's death and the escape of the Athenians, Minos orders them to be stopped, threatening to have his general beheaded if any Athenian leaves the harbour alive.
  • The New Adventures of Ocean Girl: Galiel is an alien sorcerer whose obsession with obtaining eternal life and ultimate power led him to steal one of the four magic crystals that sustain the planet Oceana. Using the crystal's power, Galiel spent the proceeding 2,000 years conquering and plundering worlds like Bandor, whose emperor he executed in front of the man's son, Prince Jobah. When his crystal's energy begins to wane, Galiel is reduced to a decrepit state, so he returns to Oceana to get the other three gems, opposed by the planet's prophesied chosen one, Princess Neri. In his quest to obtain the crystals, Galiel terrorizes the Oceanans with natural disasters, attempts to bomb the royal palace, and repeatedly possesses King Nemon to try and turn everyone against Neri. He also frequently tortures his two minions, Elgar and Moza, and is eventually revealed to be the one who destroyed the latter's home world, only sparing the infant Moza so that he could be raised to serve him. When Elgar takes one of the crystals for herself, Galiel seduces her into giving it to him, and uses it to rejuvenate himself before abandoning Elgar and setting off to get the remaining two crystals while laying waste to all of Oceana.
  • The New Adventures of Speed Racer: Caligula P. Barnum is the richest man in, and de facto ruler of, the world in the late 21st century. Barnum rules with an iron fist the only remaining city on Earth after a poison apocalypse, exploiting its people for profit and exiling anybody who disagrees with him into the toxic wastes. People exiled into the toxic wastes who—if they survive—are turned into monstrous mutants and used in slave labor for Barnum's empire or participants in deadly battle races for the amusement of the non-mutated population. After the popularity of the battle races decreases, Barnum uses a time machine to kidnap Speed Racer and force him to compete. Paranoid that Speed and his friend will try to stop the creation of mutants, Barnum sends his minion Des to assist the creator of the mutagens, Largo Sludge, in his work. Barnum ultimately sends his mutants to eliminate Speed and Racer X, having them attack Fontana Centre city and kidnap Speed's friends and family to become slaves, while supplying Largo with a new factory for his mutagens, which Barnum rigs to explode in order to create more toxic waste.
  • Ōban Star-Racers: Canaletto is a scheming, self-concerned ex-god who orchestrates the ruinous events in Eva's life to assure his own return to godhood. Formerly the Avatar, Canaletto embarked on an omnicidal, planet-destroying crusade to wipe out all life in the galaxy and restart it according to his flawless designs, before being sealed away by the next Avatar Satis. Canaletto patiently and seamlessly manipulates events in his favor for the next 10,000 years, using Eva as his pawn by causing the accident that killed Eva's mother and fractured the relationship between her and her father, ruining Rick's racing career and murdering his own servant after Rick learns of it, and personally killing Sul to place Eva as the lead of the Oban Cycle. Once he eventually frees himself, Canaletto reduces Oban to a life-deprived desert, before trying to claim the powers of the Avatar. Though Canaletto claims himself as "the Lord of Purity," his definitions of "pure" are twisted, a fact which Satis calls Canaletto out on before Canaletto tortures him to death in fury before moving on to restart his omnicidal agenda. A callous, selfish, and arrogant demon of a deity, Canaletto remorselessly ruins the lives of everyone he manipulates to further his own ascension and spares no pity to the many who ultimately die at his hands.
  • Onyx Equinox: Tezcatlipoca is a celestial god intent on wiping out humanity. Seeking yearly sacrifices of great warriors in order for them to become his heralds, when the goddess Mictecacihuatl falls in love with Yaotl, Tezcatlipoca has Yaotl's memories erased and promises to destroy him in Mictecacihuatl ever speaks of their affair. He makes a bet with Quetzalcoatl about the fate of humanity, with the winner getting all of the loser's sacrifices. Tezcatlipoca sends Yaotl to monitor Izel, Quetzalcoatl's chosen champion. Summoned by Izel alongside Quetzalcoatl, Tezcatlipoca tries to use every loophole to win the bet and kill Izel. Ultimately winning, Tezcatlipoca expresses joy at watching Quetzalcoatl slowly wither away before turning Yaotl into a normal jaguar and starting the slaughter of humanity. Cruel, petty, and vain, Tezcatlipoca proves himself to be the worst of the setting's Jerkass Gods.
  • Over the Garden Wall: The Beast is the nightmarish creature that stalks the woods of The Unknown. Finding lost travelers wandering the forest, The Beast would turn their souls into Edelwood trees after driving them into complete despair, then grind the trees into oil to fuel his lantern, prolonging his own life. When The Woodsman steals his lantern, The Beast tricks him into continuing to grind Edelwood trees and keep the lantern burning under the illusion he was saving his daughter's life. The Beast later makes a deal with Greg to show him and his brother, Wirt, the way home, however said deal was just a trick to drive the boy into despair. When Wirt attempts to save Greg, The Beast tries to manipulate him into becoming his new lantern-bearer, falsely promising Greg's soul would be kept alive within the lantern. After Wirt turns down this offer and reveals The Beast's lies to The Woodsman, The Beast makes one last attempt to kill the boys by trying to coerce The Woodsman into cutting them down with his axe. Taking deep joy from committing his atrocities, The Beast was a cruel and manipulative monster who prized his own immortality above all else.
  • Papyrus:
    • Aker, the High Priest of Set, is fanatically devoted to the rule of the god of evil and destruction. Ruling a cult of demons, Aker sends his minions who take possession of innocent bystanders to carry his plan in order to bring disasters to Egypt. Aker regularly plots to murder Pharaoh Merenre and his daughter Theti; imprison benevolent gods; and inspire wars between Egypt and other nations. His worst crimes include striking the land with a drought; poisoning the source of the Nile; causing a country wide conflagration; destroying Thebes with an earthquake and turning its citizens into stone; flooding the country with the Nile; and announcing the death of all childbearing women in the land. Furthermore, Aker is revealed to be behind the death of heroine Theti's mother and the burning of Papyrus's village.
    • Shepsheska is a felonious priest who willingly serves Aker and repeatedly betrays Pharaoh Merenre. Poisoning and attempting to usurp his master in his first appearance, he later brainwashes Princess Tethi into profaning a cat sanctuary to draw the wrath of Bastet on her family; attempts to murder Ratoufer and release the destructive Red Sphinx on the land. Abducting a dozen people, Shepsheska has their ka stolen and sacrificed to Sekhmet in order to brainwash the Pharaoh into warring against the Libyans. In his worst scheme, Shepsheska threatens to set the Nile on fire before the flood to cause a country-wide conflagration.
  • The Pirates of Dark Water: The Dark Dweller is the being behind the titular "Dark Water," a menacing oily substance that devours whatever it touches and is spreading all throughout the world. By proxy, the Dweller is responsible for countless deaths of places that the Dark Water has devoured. The Dark Dweller is focused on domination and destruction who plans to unleash its Dark Water throughout the world, focused only on consuming and controlling what it can.
  • The Powerpuff Girls (1998)'s two-parter "Knock it Off": One-shot villain Dick Hardly is a former colleague of Professor Utonium defined by his greed. Seeing financial profit in Utonium's daughters, Dick manipulates the girls into giving him samples of Chemical X and mass produces crude replicas of the girls that deteriorate easily. Displaying his callousness towards his sapient creations by ordering a perfect replica of Buttercup melted down for its excess Chemical X, Dick traps the real Powerpuff Girls and slowly, painfully drains them while boasting that he could kill the girls and have Utonium as his slave at the same time. With no charm or comedic traits to his name, Dick was a monster even before drinking Chemical X.
  • Primal (2019):
    • "Rage of the Ape-Men": The Shaman is the religious leader of the Ape-Men and responsible for the savage and brutal nature of their primitive society. The Shaman has sole control over a mysterious black goo that gives its consumer monstrous strength, and he forces the strongest members of their society to fight to the death for a mere drop. When Fang and Spear are captured by the Ape-Men, the Shaman plans to use them as prizes for the champion to take sadistic pleasure in tearing apart in a completely one-sided battle, among the countless such victims given the vast array of bones in their arena.
    • "The Night Feeder": The titular Night Feeder is a vicious, sapient predator of a dinosaur that kills solely for sport and pleasure. Slaughtering one hapless creature and leaving the remains in a manner that panics even the hardened T. rex Fang, the Night Feeder centers in a large herd of herbivores and butchers all of them, simply for the thrill of killing frightened beings. Centering in on Fang and Spear, the Night-Feeder attempts to hunt them down, savoring their terror all the while.
    • "The Primal Theory": "The Mad-Man" is a giggling cannibal murderer who barges into an English manor after escaping his asylum. The Mad-Man goes about killing everyone in the manor, often eating parts of them while they're still alive, killing all but two of the gentlemen in the Historical Society and their cook to boot. When he's trying to finish the two of them off, the Mad-Man elects against drowning one of them to instead start eating the other alive as he finds it crueler, evincing clear sadistic intelligence behind his seemingly primitive savagery.
    • "The Colossaeus" three-part arc: Queen Ima is an utterly ruthless, sadistic woman who uses her warship to sail the world looking for lands and peoples to pillage. Ima enslaved Kamau's people years ago, taking Kamau's daughter Amal as a hostage to turn him into her personal killing machine and forcing him to slaughter countless thousands of people against his pacifistic nature. Even when a peaceful island offers their goods and servitude to Ima, she coldly forces Kamau to massacre the population anyway. Upon confronting Spear, Fang, and Mira, Ima takes Fang's eggs as hostage to Spear and Fang into more warriors of hers, and forces Mira to become a sexual dancer for Ima's pleasure, killing a man in front of her just to prove a point. When Kamau and Spear lead a revolt against her, Ima spitefully tries to kill Amal and Fang's babies to punish them all.
  • Prisoner Zero: General Vykar is a brutal, ruthless, yet superficially charming Imperium officer, renowned for his habit of casually destroying planets or just killing their entire populations. In the first two episodes, he has the neutral world of Arcadia enslaved, bombarded, and then destroyed, all because of his injured pride over the fact he lost control of the Rogue, an ancient starship. Imprisoning an entire planet's population, Vykar uses the people as Bioweave capacitors, granting himself superhuman abilities. After being deprived of this, he proceeded to commit atrocity after atrocity to further for his goal of ultimate power, uncaring how many innocents died because of his actions. In the series finale he betrays the Imperium, slaughters multiple ships of their fleet — killing his own loyal soldiers — and attempts to gain ultimate power by draining the life of everyone in the galaxy who was connected to the Bioweave. Vykar is so bad that one of the plans for dealing with him at this point involved sacrificing an entire planet's population to get him away from his latest superweapon.
  • Project G.e.e.K.e.R.'s "23": GKR 23 is an artificial human with a computer brain made by Doctor Maston as a replacement for Geeker. However, after realizing his powers makes him superior to his creators, GKR 23 decided to betray them, claiming they are inferior to him. GKR 23 would later plan on taking over the world himself by eradicating all of humanity on the planet so that he could have Maston breed a new species of artificial humans for himself to rule over. When Geeker refuses to join him, GKR 23 decided to have him killed along with his friends as he deemed him a threat to his genocidal plans and world domination.

    R – Z 
  • Rambo: The Force of Freedom: General Warhawk, the leader of S.A.V.A.G.E. (Specialist-Administrators of Vengeance, Anarchy and Global Extortion), is a power-hungry despot bent on world domination. He tries to blow up the Boulder Dam as a diversion to rob Las Vegas; demands to be paid one million dollars and blows up the shipping on the Suez Canal when his demands are not met; tries to start a war between two neighboring countries by stealing a white rhino; seizes control of the Warton Missile Complex and launches an attack from the missile base to all of North America when his demands aren't met; along with his troops hijacks a supertanker, planning to cause an ecological disaster unless his demands for a warship are met; and sends Mad Dog to hijack a space shuttle called Xenon with plans to blow up satellites unless his demands are met. Not even children are safe from his wrath, as he has tried to have young peace activists killed.
  • ReBoot: Megabyte abandons his occasional moments of genuine affability to fulfill his role as The Virus in Season 3. Trapping the Guardian Bob in the Web, Megabyte uses the chance to attempt to take over the Mainframe, intent on infecting the Supercomputer and eventually the entire Net. Having his insane sister Hexidecimal killed then revived, Megabyte has her fitted with a Shock Collar, using her immense power to force her to power his weapon. Breaking into the Central Office, Megabyte decapitates the Mainframe's head Phong, torturing the still-living sprite to amuse himself; all the while tormenting the young sprite seeking to save the Mainframe, deleting countless other sprites and casually mistreating his own minions. Even once defeated, Megabyte leaves the Mainframe so damaged it is unable to recover, forcing the heroes to risk crashing the system for the chance of rebirth.
  • Ring Raiders: Scorch — real name Stanley Smith — is the leader of the evil pilot organization, "Skull Squadron". During his college years, Scorch challenges another pilot, Victor Vector, to see who's the best of them all, using underhanded tactics to do so, even so far as to murder him. Disgraced after the fight, Scorch kidnaps several scientists in order to make him stronger, and after he forms the "Skull Squadron", he causes destruction across the world. Scorch hatched several nasty plans to Take Over the World, such as attempting to cause a chain reaction of explosive volcanoes that would wipe out several major cities across the world; stealing a Kill Sat; and confiscating a plane that contains a pollen in order to unleash a plague if the world didn't surrender to him. In addition, he kidnaps a Ring Raider pilot in order to challenge Vector, threatening him by sending her to the Jurassic period.
  • Rocket Robin Hood:
    • "Warlord of Saturn"; "Who'll Kill Rocket Robin?"; "The Plot to destroy N.O.T.T.": The Warlord of Saturn is a despot scheming to rule the galaxy. He captures Little John and brainwashes him in order to destroy Robin and his Merry Men and take over New Sherwood Forest Asteroid. Allying himself with the Baron Blank, Mister Cool, and Laser in order to destroy Robin, the Warlord plans to have them killed once they've served their purpose. Stealing the Galactic Doom missile, the Warlord blackmails Prince John into surrender or he will use the Doom missile to destroy the asteroid of N.O.T.T. and all its surrounding planets, including Earth.
    • "Dementia Five" & "Return Trip": Infinata is a powerful psychic and ruler of Dementia Five. Learning that the people of the planet Gorth discovered his secrets, Infinata uses his powers to destroy their entire galaxy, Gamma Za. Finding out that the Library of Gorth is in Robin's possession, Infinata pulls him and Will Scarlett into Dementia Five and tries to persuade them to give up the library by tormenting them with illusions. Encountering Robin again, Infinata puts him on the missile heading for New Sherwood Forest Asteroid, forcing him to either disable the missile or die with the rest of his Merry Men.
  • RollBots: Vertex, a vicious spiderbot who desires to tear down Flip City's defense grid and Safety Net so as to lead a full-scale genocide against all Rollbots, enacts various atrocities in an attempt to see his plans fulfilled. These atrocities include setting apartment complexes aflame; bombing a race track and its audience; or trying to freeze every Rollbot in an endless time loop. Having zero care for his minions who he regularly abuses, Vertex murders one of them to ensure that important knowledge is kept to himself, and later butchers a rival crime lord to secure his position of power. In the end, Vertex is revealed to have wiped out Spin's entire tribe in a destructive campaign against the Rollbots, and drags Captain Pounder down with him to his death.
  • Roswell Conspiracies: Aliens, Myths and Legends: Many antagonists in this series are well-intentioned, tinted in gray, or otherwise redeem themselves. However, many are still irredeemably vile:
    • The Shadoen agent Wraith is the one responsible for nearly all the misery within the story. Stationed in Earth back in 1946 to divide the alien races and allow the Shadoen to invade and conquer the planet, Wraith butchers the real James Rinaker and assumes his identity, bombing a Conduit safehouse and killing several innocent aliens to pin the blame on the Alliance's co-leader Walter Logan before trapping Walter himself in eternal stasis to take over the Alliance. As Rinaker, Wraith traps hundreds of innocent aliens in the Alliance's prison and has little compunction in arranging torture, bombings, and heavily destructive missions with little care as to who or what gets caught in the way, whilst simultaneously sabotaging several of the Alliance's missions and endangering several more lives. After his initial attempt to pin his crimes on Nick Logan, Wraith personally murders Ms. Smith-Heisen once she gets too close to the truth without an ounce of emotion on his face before discarding his disguise, rigging the entire Alliance bunker to explode and take out half of New Mexico, and savagely murdering Trueblood with his own claws. Rejoining the Shadoen fleet and still unsatisfied with how he's being treated, Wraith tricks the Shadoen high command into being nuked by the human army and spearheads the invasion himself, ultimately resolving to blow up the moon and kill off most of humanity to conquer what remains, with his only stated regret being the loss of "breeding stock" this will incur. A traitorous, manipulative sociopath even by the standards of the world-destroying Shadoen, Wraith is the most dangerous — and vile — alien to grace the series.
    • Lord Hanek is the vampiric leader of Intracom, a powerful family of vampires disguised as a worldwide organization. Hanek is behind several of Intracom's malevolent affairs, such as burning down vast sections of the rainforest to biting and turning several innocent people into vampoid slaves. Hanek demonstrates his vileness by attempting to have the Tree of Light destroyed, which would in the process completely wipe out the Banshee Sisterhood, and turns an innocent woman into his vampoid concubine to hurt one of the Alliance's agents. Hanek truly comes into his own in his last appearance in Season 2's "Showdown": to power his teleporter technology, Hanek attempts to utilize the Banshee as living generators, in the process torturously draining the life from them and eventually killing them. Hanek endangers the life of main character Nick Logan to lure Sh'lainn and the Sisterhood into his clutches, tricks the escaped Minotauri Kahn Mort into downing a helicopter filled with his own men into a hospital, and finally forces Nick into a Sadistic Choice involving the lives of Sh'lainn and his stepfather Nathan. Always possessed of a callous sophistication in whatever situation he's in, Hanek stands miles above the other major alien antagonists in terms of depravity.
    • "Devil Inside": The Aeseri twins, Odin and Loki are rampaging psychopaths released from the Alliance's maximum security containment unit to commit wanton havoc. Shooting down every Alliance operative that pursues them, Loki is captured and contents himself with playing sadistic mind games with Nick Logan, utilizing illusions and later attacking his way through the Alliance to commandeer one of their airships. Odin, meanwhile, makes his way to Iceland, attacking a submarine and a town in Iceland before making his way into the mountains. Once the two reunite, they reveal their ultimate plan: release and control the Frost Giant and cause an apocalyptic Ragnarok for no other reason than to thrill themselves, with Loki gleefully stating he can't wait until the two reach a populated city.
  • Samurai Jack Season 5: While Aku himself, the Arch-Enemy of the titular hero, is Made of Evil, this duo from the final season proves that, sometimes, Humans Are the Real Monsters:
    • The High Priestess is the leader of the Cult of Aku, and a zealot dedicated solely to appeasing the dark god she worships by any means necessary. Drinking Aku's essence and giving birth to septuplets with Aku's dark energy within them, the High Priestess dubs them the Daughters of Aku and proceeds to horribly condition them into unfeeling weapons whose sole purpose is to kill Samurai Jack. The High Priestess systematically abuses them for years on end, searing their flesh with hot coals while they're still young and putting them through brutal, life-or-death training routines where every slight distraction means torture and beatings — sometimes simply for things as minor as looking outside. Having the Daughters graduate by having them massacre her own devoted followers, the High Priestess sends the Daughters into the world to kill Jack and callously brushes off the deaths of most of them at Jack's hand, furiously attempting to kill Ashi, her only surviving daughter, with her own hands after she finally turns on the High Priestess. An unfeeling fanatic able to rival her own dark god in evil, the High Priestess justifies her cruelty simply by stating Jack must die at any cost — regardless if that cost is her own flesh and blood.
    • "XCVI": The Dominator is a sadistic Torture Technician seemingly motivated purely by a desire to hurt people. Slaughtering a village of innocents and abducting all of their children, the Dominator painfully transforms all of the children into psychotic killing machines to be used as weapons, and tests them out on Jack and Ashi once they try to retrieve the children, with complete knowledge Jack's refusal to hurt innocents makes him easy prey. The Dominator brutally tortures Ashi upon capturing her with clear lascivious intent, gloating that children are easily manipulated tools — and that Jack's refusal to hurt them only makes him a "righteous fool".
  • Samurai Rabbit: The Usagi Chronicles: The Makkine Supreme Commander is the leader of the mechanical Makkine, under whose leadership they plunder the multiverse. It has countless world razed and what remains of their inhabitants enslaved, or utterly destroyed if the world shows too much resistance. When the Unu fight back against the Makkine, the Supreme Commander has the race brought to near extinction while freezing the survivors in stasis and reducing them to microscopic size, forcing their leader Kagehito to see the fate of his people before enslaving him to its will; it sends Kagehito to Usagi's world to open a gateway for the Makkine invasion. When the portal is finally opened, the Supreme Commander sends warbotto and the mechanical beast to raze Neo Edo to the ground, planning to subject the now free Kagehito to a Fate Worse than Death. When the heroes successfully destroy the beast, the Supreme Commander orders the entire planet destroyed.
  • Sandra the Fairy Tale Detective's "The Forbidden Room": Bluebeard is even more monstrous than his original counterpart. Having already murdered his seven previous wives, Bluebeard keeps their bodies in a room in his castle. When his eighth wife Marie discovers his secret, Bluebeard attempts to kill her along with fairy tale detectives Sandra and Fo, who have come to rescue her. A Serial Killer and attempted child murderer, Bluebeard was a surprisingly dark villain for such a lighthearted children's show.
  • The Savage Dragon:
    • Overlord is the leader of the Vicious Circle, and Dragon's most persistent, personal enemy. A Superfreak who seeks to take over Chicago and enslave every human in the city, Overlord uses his gang of freaks to commit crime and spread fear across the city. These include murdering She-Dragon's father for refusing to sell him a chip that would grant him access to the city's computer system; taking the city's train passengers hostage and attempting to have them crash into an unfinished tunnel; planting a series of bombs across town, with the final one planted inside the police department during a charity ball; and gaslighting Dragon into believing that he was the original leader of the Vicious Circle in an attempt to break his mind and ruin his life. Despite his rhetoric of freaks never harming other freaks, Overlord frequently tries to have Dragon and pals killed, and isn't afraid to torture or gruesomely punish his lackeys should they fail him, even once attempting to assassinate a freak running for mayor under the belief that only he shall lead the freaks.
    • "Possession", "Armageddon", "Ceasefire": Horde is a sapient Hive Mind of leeches from ancient times who seeks to obtain global domination. Having the ability to control one's mind by planting one of his leeches onto them, Horde seeks to have every human on Earth under his control, viewing the concept of humans lacking free will to be exciting. After Horde is resurrected after an encounter with Dragon, he manipulates the corrupt Dr. Reginald into using his new laser to destroy the ozone layer, which will cause a heat-themed apocalypse that'll allow Horde to walk amongst the Earth and take it over, later betraying Reginald when his plan's almost complete. Returning one final time, Horde possesses the minds of the Vicious Circle to get closer to the world's leaders, hoping to plant his leeches onto them and be able to control the world through them.
    • "Loathing", "She-Fiend", "Endgame": The Fiend is a demonic entity who gleefully feeds on hatred. Regularly possessing people who have a strong hatred for somebody, the Fiend regularly enacts his hosts' hurtful desires for fun. Possessing a hateful self-help guru about to give a seminar on a yacht, the Fiend tries to have everybody on the yacht killed by steering the ship into an island. Later taking control over She-Dragon to feed off her hate for Overlord, the Fiend taunts Dragon over the fact that he's endangering her. In his final appearance, the Fiend acquires a magical orb, using it to absorb the agonized souls of hateful people to increase his strength, utilizing its power to open up a portal and suck up every hateful soul from across the entire universe.
  • Scooby-Doo! Mystery Incorporated: The Nibiru Entity is a member of a normally benevolent inter-dimensional alien race called the Anunnaki, which consider him the most evil member of their entire species. He's spent untold centuries corrupting and manipulating everyone around him, especially the team pets of mystery solving teams, by perverting his species' ability to use animals as mediums to communicate, all working towards freeing him from his prison. In the process he's ruined and ended countless lives through his pawns, including Professor Pericles, whom the Entity turned into a murderous psychopath. When he's finally released in the finale, he proceeds to gleefully eat his loyal minions alive, along with Mr. E. He follows this by turning Crystal Cove into Hell on Earth and devouring the entire town with sadistic glee, planning to move on to the rest of the universe when he's done, all for the sake of power. When Mystery Inc. finally kill him, erasing him from time in the process, we see what Crystal Cove would've been like without his influence: a normal town with everyone living good, happy lives, showing just how much pain and misery he was truly responsible for.
  • The Secret Saturdays:
    • Vincent Vladislav ("V.V.") Argost is the Arch-Enemy of the Saturday family and the eerie host of "Weird World" whose lust for power is only matched by his charismatic flair for the theatrical. A Himalayan Yeti who years ago spent his days hunting and attacking travelers in the mountains, taking trophies from his kills and claiming the lives of Drew and Doyle's parents during this time, Argost eventually disguised himself as a human so as to better hunt down the legend of Kur. Argost would go on to steal the Kur Stone from the Secret Scientists in a fight that left 43 of his enemies dead, and years later concocted a series of schemes to further bring him clues to Kur, from killing the king of Kumari Kandam and spurring the civilization towards war to assisting the Naga in their murderous plans. Eventually draining the power of Kur from Zak Saturday's doppelganger Zak Monday at the cost of the boy's life, Argost hoped to first conquer, then kill, all of humanity, and nearly murdered Zak Saturday in the exact same way as Monday in an attempt to achieve his goal of subjugation and extermination of all humankind as his grandest "show" yet performed.
    • Rani Nagi is the Queen of the snake race known as the Naga, and is obsessed with the utter extinction of all humanity. At first allied with V.V. Argost in a search for Kur, Rani Nagi strikes out on her own and causes earthquakes worldwide, threatening to destroy the entire planet's surface and all life on it. Upon discovering Zak Saturday is the current incarnation of Kur, Rani Nagi tries to force the boy to be their God of Evil by attempting to slaughter his family then lead a massacre of humankind. When Zak consistently resists her corruption, Rani Nagi turns back to Argost and convinces him to use his newfound Kur abilities to wipe out the human race, with Rani Nagi later murdering Leonidas Van Rook for standing in her way.
  • Sectaurs:
    • The evil General Spidrax, lord of the Dark Domain, seeks the powerful Hyve of the Ancients to destroy Shining Realm and all within it. In his conquest, Spidrax opens the series by razing a village; traffics in slaves while gleefully planning to work two of his Arch-Enemy Dargon's friends to death when he captures them; has a corrupt magistrate try and feed the heroes to a monster which nearly destroys another village; and abuses his own men and allies, cowing murderous bandits to his command and tossing another ally who fulfills his demands to the letter to his intended death with a mocking "good job".
    • "Trapped in the Acid Desert": Crawla is the leader of the Laser Bug bandits of the Acid Desert. Known for raiding and murdering those who pass his domain, Crawla became the Arch-Enemy to Pinsor when Crawla lead a wholesale slaughter of Pinsor's homeland Kornap. Crawla wiped out every last man, woman, and child of the city before torturing Pinsor half to death, Crawla leaving Pinsor alive just to further his suffering. Later contracted by Spidrax, Crawla tries to kill the Sectaurs in the cruelest way possible, trying to destroy their water supply in the desert so they will slowly die of thirst and exposure.
  • Seis Manos: El Balde, real name Baldemar, the Orphan Maker, is a brutal drug lord who seeks power and the expansion of his organization. Having been manipulated by his mother Alejandra to murder his father as a child, Balde became a gangster who kills parents while leaving their children to become orphans, having killed Silencio's father and pregnant mother and mutilated the young Silencio's tongue. Discovering the power of Alejandra, he locked her in a tomb once she grew old, using her blood, tears, and flesh to turn himself and his own men into monsters, which Balde plans to use to take over San Simon. With zero care for anybody, even his own men, once Balde takes over San Simon, he kills the drunk Piyojo; murders the town mayor in front of the townsfolk to send a message, while also fatally wounding Garabina; murders every adult in town; and keeps the children as slave labor for his drug operation. Faced with Alejandra, Balde sheds all love for his mother by trying to kill her in order to prove himself as a true man, a sadist without a heart.
  • Shadow Raiders: The Beast Generals, the malevolent servitors of the world-devouring Beast Planet who help their master The Beast scourge entire solar systems and destroy all worlds within them, each qualify in their own right:
    • Lamprey is a master of deceit and subterfuge who weakens worlds from the inside out through complex gambits, occasionally pausing to murder people who cross her path for little other reason than to amuse herself. Lamprey introduces herself tricking Emperor Femur into installing a device meant to drain all the life from Planet Bone. After this, Lamprey possesses Tekla and tries to use her to destroy the Alliance from the inside out, contenting herself with subjecting her to horrific Mind Rape of her planet's destruction and trying to slowly kill her from the inside once this fails. After this fails, Lamprey murders a resident of Planet Fire and pins it on Jade's hands, intending for her to be horribly executed by being dipped into a fall of lava. Lamprey's final crimes in the series stem purely from petty spite: Seeking revenge against Tekla, Lamprey has her Beast drones attack a bar with the intent to kill everyone inside, personally disintegrates Captain Blaze once he gets in her way, and furiously attempts to kill everyone who stands between her and Tekla before her own demise.
    • Blokk is a brutish warrior who firmly believes in the power of absolute force over everything else, preferring to overrun worlds through his armada to destroy all they see whilst basking in the carnage. Blokk's repeated attempts to attack the planets in the Cluster result in numerous deaths and the successful destruction of Planet Jungle. Blokk personally attempts to trick Cryos into killing his own daughter whilst leaving his planet vulnerable, and grows more and more vicious after his repeated punishments at the hand of the Beast. In the finale of the series, Blokk takes over Planet Rock by force by besting and killing Lord Mantle, while promising to give the Alliance members he's captured — two children among them — a slow death at the Beast's hands. Once he's left stranded on Rock, Blokk slaughters his way to Rock's World Engine, personally executes Feldspar, and sets the entire planet on a collision course with the nearest star out of sheer spite.
  • Silverwing: Goth is a giant cannibal bat from South America. Captured by humans, he's sent to lab in a North American city for study. After escaping the lab, Goth begins to kill owls and birds, which General Brutus blames on the Silverwing bats, causing him to persecute them. Killing an owl hunting the Silverwing bat Shade, to seemingly befriend Shade, Goth plots to have Shade lead him to his colony so he may devour them all. Shade discovers Goth's true intentions after finding the corpse of a Brightwing bat Goth had eaten. Later, Goth and his brother-in-law Throbb eat a coven of bats and take the metal bands they were wearing as trophies. When Shade and Goth are trapped in a mine, Shade suggests they work together to escape, but makes Goth promise to allow him and his friends to live, a promise Goth instantly reneges on when he is out of danger. Near the end of the series, Goth teams up with the wolves to take over the forest and goes on a killing spree against the owls to fulfill his part of this deal.
  • Skeleton Warriors: The suitably-named Baron Dark was an ambitious nobleman who hungered to steal the Lightstar Crystal powering the lands of Luminaire. Dark arranged for the King's shuttle to crash in hostile territory, and manipulated his younger son Joshua into going for the Lightstar Crystal himself before attempting to steal it. Its energies made the Baron's evil manifest fully as he became the first Skeleton Warrior, an immortal living dead creature who transformed all his forces into the same. The Baron attacked Luminaire's civilians and upon discovering he could only turn evil people into Skeletons, Dark furiously ordered the rest of the population murdered, only relenting when one of his men reminded him they'd need slaves. Dark would force a population's compliance by starving them and withholding medicine to force them to do his bidding, attempted to wipe out the ape-like Semigons to steal their refinery, and once he gained the Lightstar Crystal himself, Dark attempted to remake the world into a hellish landscape where only his chosen Skeleton Warriors would survive.
  • Skyland:
    • Oslo is a Commander of the Sphere; a powerful Seijin; and a megalomaniac who believes himself to be The Chosen One who is destined to rule all of Skyland with the help of a prophesied "Lady of Light" who will give him the means to take over the Sphere. After imprisoning his old friend Mila, Oslo begins hunting for her daughter, Lena, a young Seijin who he is convinced is the Lady of Light. Regularly terrorizing "the peasants" and crushing all resistance to the Sphere's regime, Oslo worst atrocities include blowing up a hidden refuge full of orphaned Seijin children; increasing his own power by sucking the life out of his kindly twin brother Darius; and rampaging through Temuera in search of a power-enhancing relic, at one point attempting to force the Temueran leader to talk by threatening to make him watch as his people are either enslaved or executed by the Sphere's Brigadiers.
    • "Secret Power": Shinseiki is a Seijin who was kicked out of the Guardian Academy due to her obsessive belief that she alone was destined to bring about the reunification of Skyland by telekinetically reshaping it back into the Earth. Abducting other Seijins, Shinseiki uses a machine to leech their power to add to her own, and is implied to have fatally drained numerous Seijins by the time she captures Lena. While she admits that her attempt at reassembling the Earth will probably ravage entire inhabited Blocks and kill thousands, Shinseiki dismissively states that that is a small price to pay for "my kingdom" and the chance to get back at the Sphere for expelling her from the Guardians. When Dahlia tries to stop her by challenging her to a fair fight without any powers, Shinseiki initially plays along, but then cheats and uses her abilities to try and kill Dahlia and Mahad before attempting to suck the life out of Lena and her other captive Seijins.
  • Solar Opposites: Out of all the people Yumyulack shrank down and sent to The Wall, the following are the vilest:
    • Season 2: Ethan was a disturbed man who tried to suffice his murderous impulses by causing the Flooding of the Nerds, killing countless people. After surviving, Ethan becomes a Serial Killer with a god complex, having already gruesomely murdered 5 people before getting detained by Halk. Ethan would proudly confess to committing these murders with plans to continue his killing spree by blackmailing The Wall's leader, Tim, into letting him go.
    • Seasons 3-4: Sister Sisto murdered the previous leader of the Bowinian Church to bring herself to power. Revealing Cherie's child to the residents of the Wall, Sisto has the child branded to make her a false symbol to the Church. Sisto is revealed to have turned the Church into a cult, having anyone who enters said Wall executed if they do not accept Jesse as their god, with their heads being displayed on a wall as a warning. When one of the residents discover the temperature decreasing at an alarming rate, Sisto reveals that she had been personally lowering it before having said resident executed. After Cherie and Montez manage to escape, Sisto sends her soldiers after them, many getting killed by the traps left for them. After Sisto discovers that they had already escaped, she abandons her soldiers and leaves them to freeze to death, revealing to Nova that she never believed in Jesse to begin with and was lying to her the whole time about reviving her husband, breaking Nova in the process before attempting to stab her to death.
    • "The Cubic Lattice Crystallizer": Platinum Stevie is a survivor of The Wall's flood who would become leader of the Cannibalistic Muck People, having them kill and eat anyone they see. Encountering a party led by Cherrie and Halk, Stevie seemingly complies with their efforts to establish diplomatic terms, only to kill and butcher their ally, Joe Sanders, and feed them his remains, before attempting to kill the party and declare her intent to reach the Upper Wall to kill and devour as many people as possible.
  • Spicy City:
    • "Sex Drive": Otaku is a technician who works for M&G Corporation, and is involved in virtual prostitution. To this end, Otaku abducts prostitutes, experiments on them, and extracts their personalities on behalf of his superiors, leaving the prostitutes catatonic, subsequently reworking their personalities on a disc to make them compliant. Capturing the cyborg prostitute Virus, Otaku extracts her personality and programs her to seduce his superiors at M&G and extract their intelligence so he can overtake them. When Virus returns, Otaku gropes her as he extracts information from her, unaware that police officer turned taxi driver Nisa Lolita is recording the exchange.
    • "Raven's Revenge": Corbin is the CEO of AlternaCeuticals, the company that created Raven. A psychopathic eugenicist, Corbin wants to wipe out all those he's deemed genetically inferior and aberrant, and plans on doing it with a virus that he tests on Raven and carnival freaks. When symptoms begin to manifest in the carriers, Corbin has the crowded carnival bombed under the pretense of containing an outbreak before instructing his men to Leave No Witnesses as they move in to capture Raven. When confronted, Corbin implies that he was responsible for the death of Raven's mother, and rants about how he is going to eliminate all the "mutants and freaks" with his plague, which he also intends to profit from thanks to his "good fiscal policy" of Withholding the Cure to diseases in favor of overpriced treatments that are developed as slowly as possible.
  • Spirou (1992-1995 series): Cyanure—French for Cyanide—does everything her comic counterpart did and goes much farther. When she comes across one of the Count's creations, which can reduce anything or anyone's size, she uses it to reduce anything's and anyone's size for her own amusement. A sadist, Cyanure laughed at Spirou and Fantasio's cries of pain when she uses speakers at maximum volume against them, and laughed at a tied-up mini Fantasio when a toy train was about to run over him. In an attempt to kill all humans by mass-producing herself into an army, she kidnaps Professor Sushiyaka to record his paralyzing scream. When he refuses, Cyanure attempts to kidnap her nephew, and when capturing Fantasio instead, she dismantles and set aflame one of her own clones in front of Sushiyaka and threatens to do so to Fantasio if he doesn't record the scream. Even Cyanure's supposed care about machines when she talks about liberating them from humanity's control is subverted when she badmouths Domus's robots and shows no empathy to their destruction—nor Domus's, who was completely faithful to her—proving that Cyanure ultimately cares for no one but herself.
  • Stargate Infinity: Commander Da'kyll of the Tlak'kahn Empire is the ruthless, bloodthirsty leader of the Warrior caste, known for his habit of turning his adversaries into living trophies in suspended animation while he works on finding a way to break their spirits and turn them into mindless servants. After orchestrating the massacre of Major Gus Bonner's old team, Da'kyll has him framed as a traitor to Stargate Command, and relentlessly pursues him and his new squad across the universe, intent on capturing Bonner's mysterious alien ally Draga, who Da'kyll is convinced is one of the Ancients. Da'kyll at one point takes a village hostage, and threatens to destroy it unless Bonner surrenders to him; when Bonner does give himself up, Da'kyll orders that the village be razed anyway before deciding that it would be more fun to let its inhabitants die slow deaths from an illness that is ravaging them. When the Mardan, one of the Tlak'kahns' Slave Races, help him capture the Stargate crew, Da'kyll destroys the team's cure for a plague that the Mardan are suffering from while noting that if the Mardan manage to survive the sickness on their own, they will have proven worthy enough to be used as Cannon Fodder. Da'kyll threatens soldiers who fail him with torture, murders his professional rivals, and frequently flouts the authority of the Nax'kan Council, who he intends to overthrow using the knowledge and power of the Ancients.
  • The Story Keepers:
    • Nihilus, the centurion in service to Emperor Nero, is defined by his ruthlessness and utter lack of conscience. After participating in the burning of Rome, Nihilus continues to lead The Purge of Christians, having countless victims captured to be thrown to lions. At one point Nihilus implements a plan to have entire neighborhoods burned down, endangering hundreds of people. Upon learning that his fellow centurion Tacticus was secretly a Christian, Nihilus attempts to have him executed. Learning that Ben was a Christian leader, Nihilus arranges a public crucifixion for him while attempting have his wife and adopted children burned alive. Murdering his colleague after he saves Ben’s life, the disgraced Nihilus follows the heroes into the desert, planing to kill Tacticus and leave children to die of thirst as revenge.
    • "Starlight Escape": King Herod was a paranoid and temperamental tyrant who ruled over Israel. After being informed of the birth of King in Bethlehem the new King in Bethlehem by the traveling Magi, Herod tries to manipulate them into finding the child for him in order to kill him and secure his own rule. After the Magi don't return with the location of the child, Herod spitefully orders his army to kill every male child in Bethlehem under 2 years old.
  • Street Sharks:
    • "Shark to the Future" & "Shark Wars": The future version of Dr. Luther Paradigm, like his past self, is the Arch-Enemy of the Street Sharks. In the future, Paradigm perfected an air born gene-altering virus that transformed everyone in Fission City into his mutated slaves brainwashed into serving him. Deciding to spread the virus across the world, Paradigm becomes the despotic tyrant of the Earth and tries to eradicate those who were immune to his virus. After being foiled by the Street Sharks from the past, Paradigm rebuilt his Time Machine, and he helps his past self create the virus; leads an invasion in the present day; and kidnaps one of the Street Sharks, Jab, and brainwashes him into his loyal servant. Paradigm tries to have Jab attack his brothers and mutate them into brainwashed servants.
    • Season 3: Bad Rap is the leader of the Reckless Raptors, an intergalactic criminal who ravaged his home world and move across the galaxy to spread chaos and destruction in his wake. Upon being reawakened by Paradigm on Earth, Bad Rap contacts his minions to eradicate the human race and rule the planet. Bad Rap launches nuclear missiles unto major capitals across the world so that the entire planet would wage war upon each other and destroy themselves for Bad Rap to rule what's left, a tactic he uses on other planets. In "Shark Quake", Bad Rap tries to activate all of the world's volcanoes to make the world uninhabitable for humanity, endangering the lives of millions. In "Jungle Sharks", Bad Rap tries to set the Amazon rainforest on fire to prevent the Street Sharks and Dino-Vengers from finding a cure for a deadly disease. In "Trojan Sharks", Bad Rap attempts to launch the Dino-Vengers to be trapped in space forever while trying to restart his plan of kick-starting a global nuclear holocaust.
  • Superbook (2011):
    • Satan himself is the cruel, manipulative devil who rules over Hell and wants to taint all of God's creation. After leading a failed coup in Heaven where he murdered many angels, Satan corrupts Adam and Eve, unleashing his influence onto the Earth and allowing him to spread death and chaos. Satan causes natural disasters for fun, orders his demons to drive people insane, and personally ruins the life of Job, killing many of his servants and sons in the process just to try to prove a point. Satan's final plan is to destroy most of humanity and enslave the rest, a plan which he personally tries to start by murdering two children while mocking them.
    • Haman is the despicable advisor to King Xerxes who, after feeling personally insulted when the Jew Mordecai won't bow to him, decides to exterminate every Jew in Xerxes's kingdom. Haman tricks Xerxes into believing the Jews are a violent and treacherous people and sends out the order to kill every Jew young and old in the kingdom, personally constructing a gallows in his own home so he can watch with glee at Mordecai's death by hanging.
  • Supernatural Academy: The Dragon King is a powerful dragon-shifter who started a war of conquest that devastated the Faerie realm. Defeated and sealed by the combined efforts of supernaturals, he cursed the descendants of the individuals who defeated him to be his servants when he returns to either destroy or conquer the human world, leading to the creation of the Dragon Marked. After being freed by the efforts of Archibold Kristov and the East-West Dragon Marked twins, the Dragon King rewards them by brainwashing the twins into his slaves and burning Kristov alive. He tries to kill Mischa and Jessa as a prelude to raining death and destruction on humans and supernaturals alike.
  • SWAT Kats:
    • Dark Kat is one of the Swat Kats' most recurring, and wicked, villains. A complete madman obsessed with the death of the Swat Kats and the destruction of Megakat City, Dark Kat is introduced trying to use a nuclear weapon to annihilate Megakat City and its thousands of residents, attempting to force Lieutenant Feral to watch the carnage as it unfolds. Later attempting to turn the Swat Kats into ground meat while using their jet to frame them for opening fire on civilians and blowing up entire buildings, Dark Kat follows this up by convincing Razer he severely wounded innocents to throw him off his game while Dark Kat uses a robotic arachnid to attack and hopefully tear Megakat City to shreds. In his arguably worst outing, Dark Kat makes an alliance with Dr. Viper, using him to rebuild the Metallikats then install chips in them that allow Dark Kat to torture them at his leisure. Using the Metallikats and Viper, Dark Kat lures the Swat Kats, Feral, and assistant mayor Callie Briggs into a trap to kill them all, ordering the Metallikats to kill Viper when he outlives his usefulness, and ultimately attempts to blow up the entire base as a last ditch effort to kill the Swat Kats, their friends, and all of Dark Kat's own allies in one fell swoop.
    • Dr. Viper was once Elrod Purvis, a greedy scientist whose plan to sell the Viper Mutagen to the highest bidder ended with his supposed death and subsequent mutation into the evil Viper. In his schemes to destroy Megakat City and replace it with a festering "Megaswamp City", Viper regularly attempts to mutate and murder all he can through his chemical weapons and monsters; painfully transforms one-shot villain Morbulus into a mindless bacteria creature that he sets loose on Megakat City, leading to dozens of deaths, including that of Viper's former colleague Zyme; attempts to drown the entire city in toxic spores; teams up with Dark Kat; and finally floods the city with mutative chemicals in a bid to mutate everyone within the city. Regularly murdering innocents in his attempted conquest and seeing beauty only in the fetid and festering, Dr. Viper was about as remorselessly evil as his sinister appearance would suggest.
    • "When Strikes Mutilor": Mutilor is a brutal mercenary who takes over a ship from a peaceful race called the Aquians and attacks Earth, planning to drain every drop of water from the world to sell it off, saying that if Earth dies as a result, then that's just business. When the heroic SWAT Kats interfere, Mutilor tries to torture them to death with electricity, and when the ship is taken, Mutilor attempts to destroy it out of spite so that it crashes into Earth and causes a devastating catastrophe that could easily kill every cat on the planet.
  • Sym-Bionic Titan:
    • General Modula is a cold, cruel man responsible for all the misery within the series. A treacherous man who once served proudly under the Galalunan Kingdom before being mistakenly thought dead by the King, Modula lets his cruelty consume him, allying with the monstrous Mutraddi and launching an invasion on Galaluna that leads to countless innocent people killed and the rest enslaved, with Modula murdering many of the rebels himself. Intent on utterly breaking the will of the Galalunan people by killing Princess Ilana, Modula sends the Mutraddi to wreak swaths of havoc and death on Earth to kill her, even using a living bomb called Tashy 497 to potentially decimate the entire planet to get at her—vaporizing his own minion once he fails to do his job and threatening his successor with the same fate should he fail him. A man who has long abandoned any honorable traits he may have had, Modula is a walking nightmare worse than even the literal monsters he rules over.
    • "Escape from Galaluna": The unnamed Galalunan commander is a smug, ambitious traitor who uses his front as an obstructive, obnoxious military head to ensure the death of captive hostages while pinning their deaths on Lance and leaving him to hang. In truth having allied with Modula, the traitor sells out his entire planet to the Mutraddi forces to see the royal family killed and its populace decimated and enslaved, looking over the carnage and gloating that the only reason he sold his planet out was to lead Galaluna into an age of "conquest and strength" — and the prospect of a vast reward from Modula.
  • A Tale Dark & Grimm episodes 4-6: The Warlock, also known as the Handsome Young Man, first appears to be a kind person who flirts with Gretel and gives food to the orphanage. However, it turns out he is actually a warlock who for the past hundred years lured in young girls to his manor, ripping their souls out in the form of doves to fuel his magic, and keeping them locked in small cages indefinitely. He then erases the memories of the girls from all the townsfolk to make them still think he's a hero. He treats his own mother like a slave, binding her in shackles and has never shown her kindness, and she agrees that he must be stopped. And after he realizes Gretel knows his secret, he begins terrorizing her for kicks before mind-controlling the entire town to attack her.
  • Tales of Arcadia:
    • 3Below: General Val Morando is a would-be Galactic Conqueror who, in the premiere, takes over the planet Akiridion-5 and reduces it to a fascistic hellhole through a brutal coup. Morando plays Varvatos Vex, the defender of the royal family, for years, having murdered Vex's entire family alongside hundreds of other innocent people simply to use a fake pretext to manipulate Vex. When Vex catches onto his lies, Morando gleefully pledges to make Vex watch as he kills his new Family of Choice instead. Throughout the series, Morando murders failed minions and bounty hunters, sometimes for reasons as petty as delivering bad news; strings along the bigoted Colonel Kubritz before killing her as well when she disobeys him; kills many of the heroes' allies; and attempts to transform himself into a god in order to destroy and remake the entire universe to give it the "order" he so craves, nearly wiping out much of Arcadia Bay in the process.
    • Wizards & Trollhunters: Rise of the Titans:
      • Bellroc, Keeper of the Flame, is the master of the Arcane Order and one of the primordial demigods who shaped the universe. Discontent with humanity and their corruption of their order, Bellroc grew blind to the damage they inflicted upon the world, simply deciding to destroy it and start over. Bellroc mortally wounds King Arthur to fully corrupt Morgana le Fay and see her overrun and annihilate humanity, attempting to awaken the Titans by forcing the one repenting member of the Order, Nari, to assist despite her will. Bellroc proceeds to awaken the Titans and lead an attempt to uncover the Heartstone at Arcadia Bay, intending to destroy all that lives according to their own ego.
      • Skrael of the North Wind is Bellroc's subordinate and partner in the Order, being perhaps the most viciously sadistic of the trio. Forsaking his own vow of neutrality, Skrael happily joins the fight to kill many humans with intent to completely exterminate them. In between battles, Skrael enjoys torturing his captives, as he viciously does to Steve, later showing a similar glee in hurting Nari as well before forcing her to attempt to awaken the Titans and unmake all in existence.
  • Tenko and the Guardians of the Magic: Vell is an unscrupulous industrialist who, unsatisfied with the vast riches that he has acquired from plundering the resources of various countries, made a deal with a trapped extra-dimensional entity that had previously destroyed Atlantis. In exchange for unfathomable power, Vell will release the creature and let it ravage the Earth. Needing one of the Starfire Gems to unleash the beast, Vell slashes, burns, and bulldozes his way through the Amazon in search of the Emerald Gem. After acquiring the stone, Vell uses its power to mutate his long-suffering pet jaguar into a monster that he sics on Princess Tenko, who frees the jaguar and shatters the Emerald Gem. Still possessing half of the Emerald Gem, Vell proceeds to manipulate Tenko's rival, Jana, into helping him steal the other half of the Emerald Gem from Tenko, who they lure into a trap by causing a destructive eruption at Mt. Vesuvius. Once he no longer has any use for her, Vell tries to feed Jana's soul to his imprisoned master deep within the ruins of Atlantis.
  • Thunder Cats 2011:
    • Mumm-Ra once plundered the cosmos searching for the legendary Power Stones in his quest to rule the universe. Commanding an army comprised of a number of races he enslaved using explosive collars placed around their necks, Mumm-Ra ordered the destruction of a star in a highly-inhabited solar system, killing billions in the process, simply so he could use the remains of the star to forge the Sword of Plun-Darr. Defeated and sealed inside a coffin, Mumm-Ra is freed by Grune, and soon attacks Thundera with his army, killing Lion-O's father Claudus and enslaving most of the Thundercats. After taking over Thundera, Mumm-Ra proceeds to torture cleric Jaga for information about the Book of Omens. Resuming his hunt for the stones, Mumm-Ra has his army attack the Elephant village suspected of harbouring the soul stone. After failing to trick Lion-O and his brother Tygra into killing each other, Mumm-Ra frees the sadistic killers Kaynar and Addicus to keep his increasingly disillusioned army under control and has Pumyra, who has fallen in his invasion of Thundera, revived to serve as his spy. In the two-part series finale "What Lies Above", Mumm-Ra has the flying city of Avista attacked to steal the Tech Stone, uncaring that this would cause the entire city to fall from the sky.
    • The Ancient Spirits of Evil are Mumm-Ra's masters and are the ones who give him his powers. They task Mumm-Ra with gathering the Power Stones and ruling the universe in their name, ordering him to destroy the Plun-Darr star and kill billions in order to forge the Sword of Plun-Darr. When the Tiger Tribe summons the Spirits to save them from a deadly plague, the Spirits try to make the Tribe's leader Javak kill his newborn son Tygra because they predict Tygra will become their enemy. When Javak instead sends Tygra away, the Spirits let the plague kill the entire Tribe before cursing them to exist as undead spirits who become savage beasts every night. When the adult Tygra and his brother Lion-O encounter the Tiger Tribe, the Spirits manifest and order the Tigers to kill the brothers.
    • Grune was one of the most respected soldiers of the Kingdom of Thundera who secretly desires the throne. After he and his brother in arms Panthro are sent to search for the Book of Omens, an enraged Grune frees and pledges himself to Mumm-Ra, seemingly killing Panthro in the process. Grune helps lead the lizard army to plunder Thundera and enslave its people, even helping organize the death of the king. As Mumm-Ra's right-hand, Grune occupies the elephants' village, suspected of harboring the Spirit Stone, and threatens the lives of its inhabitants. In the end, he even attempts to betray Mumm-Ra, and as he is being sucked into the Astral Plane, tries to pull Panthro with him.
  • Time Jam: Valerian & Laureline:
    • Raymond de Tancarville is a tyrant who steals away the Earth itself and keeps humanity trapped in Medieval Stasis to rule unchallenged, enforcing his rule with robots that have been shown to blast the populace indiscriminately at sign of challenge. To rule the galaxy, Raymond created the Vlagos race and, upon finding a telepath to guide them, murdered her parents and mind-wiped her into believing her own ruler was responsible, in order to have her turn on her people and lead the Vlagos to dominate and destroy countless worlds. To fulfill his ambition, Raymond also tries to murder Valerian and force Laureline to marry him, gloating he'll have her mind rewired to make her a willing, submissive and obedient wife.
    • "Time of Troubles" & "Springtime in Paris": Zlego Zhardan is a greedy man who, 300 years ago, invaded the planet Akba to claim its natural resources. After Akba is hidden inside the Stone of Creation by Ozer Ran the Righteous, Zlego schemes to get his hands on the stone. Kidnaping Valerian and Laureline and forcing them to bring him the stone, Zlego orders his army to wipe out all life on Akba. Following his arrest by Valerian, Zlego attempts to have Laureline killed and Valerian's memories erased.
  • Toonami:
    • The Intruder & The Intruder II: The Intruder, once a mindless, indestructible Blob Monster, became something far worse after consuming TOM 1. Gaining sapience after absorbing TOM 1, the Intruder plotted revenge on TOM for defeating him. Having become proud of the thousands of lives it previously absorbed, the Intruder found TOM 4's signal and gleefully absorbed him and his cohosts Flash and D. Finding the Absolution Mk. III, the Intruder sets out to make TOM suffer before killing him by assimilating SARA and bragging about it to TOM, before trying to kill TOM with the Absolution's canons.
    • The Forge: The Commander of the Forge, "Booger", is a battle-hardened alien who seeks galactic domination. Creating yellow, sapient TOM units to serve as disposable labor for him and his species, Booger destroys every Clyde unit and captures TOM, SARA, and the Vindication, planning to release the Vindication's true destructive power on the galaxy. Murdering TOM 5 after he starts a rebellion, Booger orders his men to destroy every TOM unit who rebelled, telling the new TOM 6 that he'll die a forgotten failure.
  • Totally Spies!:
    • Helga Von Guggen is a greedy fashion designer who makes "seamless" fur coats by kidnapping innocent people, injecting them with a serum that turns them into Beast Folk, then skinning them alive in what appears to be a giant industrial crusher. She makes her debut having already done this to a boat with two hundred people on board, bragging about one of her coats, claiming that it's "genuine lawyer." She later designs a line of apparel that crushes people who wear them, with heavy implications that it manages to kill an innocent shopper off-screen in the opening minutes of the episode it was introduced.
    • "Stuck in the Middle Ages with You": The unnamed Black Knight is in fact a modern aged and misogynistic young man, descending from a royal lineage. Seeking to restore his ancestors' former power and rule the modern world, the Black Knight uncovers time travel, and abducts military scientists and personnel to the Middle Ages and control the destructive Kill Sat E.N.D. to overthrow a past benevolent king. As the Black Knight, he aims to become a warmongering tyrant, leading attacks on the kingdom, using E.N.D. to decimate the King's knights, threatening to destroy his castle and village unless he hands over his crown. Upon taking over, the Black Knight plans to further conquer the medieval world, starting off by having E.N.D. fire upon a village, setting it ablaze.
    • "Creepy Crawly Much?": Max Exterminus was a successful but disgruntled exterminator, who decided to instead to lead and rule over all bugs if he couldn't exterminate them. Taking to gene splicing, Exterminus mutates himself into an insectoid hybrid to lead swarms of insects, and plans to wipe out all non-bug life on Earth and rule over what's left. Raiding military bases for their data, Exterminus creates a rocket filled with weaponized bug venom, planning to launch it into the Earth's jet stream and poison the atmosphere. Taking a lecherous fixation on Alex, Exterminus attempts to forcibly mutate her to be his "Queen" as he launches his rocket, making a remark about the larvae they'll have together in the new world.
  • Trese:
    • Datu Talagbusao is the savage War God who has caused countless instances of death and destruction in a quest to end the world. Upon being summoned to meet his twin children, Talagbusao murdered their mother and tried to consume them, only being imprisoned again by the power of Lakan Anton Trese. Returning later to manipulate mayor Sancho Santamaria to terrorist activity, ripping his way out of his host General Villars, Talagbusao attempts to corrupt Alexandra Trese so they might end the world and destroy every living thing upon it, even enslaving his own sons to assist.
    • Mayor Sancho Santamaria is a crooked politician who murdered his mistress and then murdered her ghost as well. Having slums burned down to enslave the locals, he also tricks residents of lower income areas into "relocation", but all go to the same place: the markets of the Aswang, where the rapacious monsters will keep them caged and devour them while Santamaria profits. Returning in prison, Santamaria organizes a series of terrorist attacks across the Philippines, intending to see the nation burnt down so he may take control.
  • The Twins of Destiny: The Empress Dowager of China is a wicked tyrant who lives in lavish luxury while her oppressed, poverty-stricken people starve and are terrorized by her soldiers and eunuchs. When two children who were prophesied to bring about her downfall are born, the Empress orders them killed, has their doctor imprisoned and tortured, and turns their fathers into inanimate — but still awarestatues, because death would be "too easy", as a punishment for the "defiant act" of bringing her would-be usurpers into the world. After learning that the children were secretly smuggled to France, the Empress gives her eunuchs free rein to destroy anything that gets in their way in their mission to slay the twins. When the twins make it to China, the Empress deploys her armies against them, and allows the soldiers to raze villages and summarily execute people in an attempt to flush the children and their allies out. The Empress regularly threatened her servants with death and mutilation, had planned on murdering her Evil Sorcerer on the unfounded suspicion that he was disloyal, and foregoes executing her incompetent head eunuch in favor of demoting him, because the eunuch spending the rest of his life haunted by his disgrace is a far crueler and more amusing punishment than death.
  • The Venture Brothers: Dr. Jonas Venture is the self-absorbed and abusive father of Thaddeus "Rusty" Venture who masquerades as a noble and beloved adventurer and scientist. Taking Rusty on dangerous adventures since he was three years old, Jonas allowed him to be trapped, tortured and put in harm's way, to allow himself the excitement of "rescuing" Rusty as the hero. When working on scientific inventions, Jonas frequently grew bored of his works with dire consequences, in one instance leaving a group of orphans to suffer drug-induced nightmares after an A.I. he created ran rampant, much to Jonas's apathy. His own team meaning nothing to him, Jonas viewed his bodyguard as property, taking him from his "best friend" Blue Morpho as "payment", and turned another into a violent Blood Knight by forcing him to use dangerous drugs. Ruining Morpho's life, Jonas coerces the happily married man into an orgy, then blackmails Morpho with the knowledge and forces him to do his dirty work, and later resurrects Morpho into a cyborg slave, which earned the disgust of his team. After spending several decades in a mostly-dead state, Jonas attempts to have the cyborg Morpho killed so that he may steal his body for himself, and then flies into a rage and tries to do it himself once this order is refused. Killing any villains he grows bored of, Jonas proves under the exterior of grand heroics he paints himself with to be an utterly despicable Psychopathic Manchild.
  • Victor and Valentino's "The Collector": Chip is an antique collector, obsessed with keeping his merchandise in mint condition. Growing unsatisfied with collecting only items, he decided to collect people. He turns them into dolls, where they are conscious, but trapped, a fate which he has inflicted on many people, including Valentino's younger brother. He is more than willing to inflict the same fate on Valentino when he tries to rescue them.
  • Wakfu & Islands of Wakfu:
    • Rushu is the king of the Shushu, a race that takes pleasure in nothing but destruction. Rushu slew almost all his primordial brothers at the beginning of creation to ensure there would be no rule to his reign; regularly murders his own Shushu with casual abandon; and has annihilated all life on his native world of Shukrute, a fact which has him constantly scheming ways to invade the World of Twelve to devastate it as well. Kept only in place by the sacred pact of the gods, Rushu finds numerous ways to subvert or simply outright break the pact, occasionally personally appointing Shushu to wreak swathes of bloody havoc and destruction while routinely tempting souls into becoming more Shushu. Rushu collaborates with the Eliatrope traitor Qilby to gain access to the World of Twelve to start razing everything in sight, his advent upon the world only thwarted by his Arch-Enemy Goultard.
    • Orgonax was the youngest and the prince of the Mechasm people whose heart was stolen by the Eliatrope traitor Qilby to foment war between the two people. Beyond any hope of reason, Orgonax, in retribution, spearheaded a war with the end goal of the utmost destruction of the Eliatrope people, slaughtering countless numbers of them until they managed to escape the Mechasms' wrath. Orgonax persisted his genocidal crusade long after the rest of his people had retired, tracking down the Eliatropes to the planet that would become the World of Twelve and restarting his campaign of destruction all over again. A being of absolute, unrelenting hatred, Orgonax would let nothing—from the murder of the Eliatrope children, to allowing his Lu-Fu servants to suck the Wakfu dry from countless other species merely cohabiting the planet with the Eliatropes—stop him from exacting his revenge.
  • WesToons (aka WinneToons):
    • Chief Matto-Sih, unlike the other largely peaceable Natives, is an arrogant renegade who only cares about wealth, power, and eliminating his rival, Winnetou. Matto-Sih conducts violent raids against both settlers and Natives alike, and during one of them nearly kills a baby with a hail of Flaming Arrows. Matto-Sih frequently collaborates with the unscrupulous logger Santer, but just as frequently betrays him, at one point abandoning Santer's men to die in the wilderness while also planning to later dispose of Santer. Matto-Sih has enslaved Winnetou's tribe in order to force them to dig for gold; framed other Natives for potentially deadly attacks on railroad workers; attempted to burn down an entire town full of people; and brainwashed another Chief into siding with him for the sole purpose of using him and his tribesmen as disposable Cannon Fodder against the U.S. Cavalry.
    • Harry Melton is a conniving weasel of a man who is introduced attempting to knife an onlooker who had interrupted his rigged game of poker. After installing a fake sheriff, Melton steals all of the gold that prospectors had stored in the sheriff's office, pinning the theft on Old Shatterhand. Melton then abandons his henchmen and tries to kill the phony sheriff after rallying an angry mob to hang Shatterhand. Melton also frames the Apaches for cattle rustling, causing violent tensions to arise between them and the settlers, and tries to crash a train just kill Shatterhand. Melton later uses two Apache youths as shields against booby traps during the search for a legendary treasure, and attempts to gun the two children down once they reach the riches, even though they had earlier saved him from a Pit Trap. In his worst outing, Melton abducted Apache women for use as slaves in a mine; when Shatterhand and Winnetou began closing in on him, Melton covered his tracks by blowing the mine up with all of the slaves still in it, afterward quipping, "You know what they say, the only good Injun is a dead Injun!"
  • Wild C.A.T.s's "Lives in the Balance": Majestic is far more villainous than his comic counterpart. The former commander of the Kherubim forces, Majestic is utterly obsessed with achieving his "destiny" of conquering the galaxy with the help of the Orb. In the past, Majestic crashed his spaceship into the Daemonites' spaceship, not caring about the lives of his own men, causing them to crash on Earth, while he escaped. Awakened in the present, Majestic immediately began construction of the Vortex Device, which he planned to use to destroy the Daemonites, simply to eliminate the "competition". Stealing a quantum energy module from the military base, damaging its core in the process, which endangered all the workers there, Majestic used his Vortex Device to lure Helspont to his trap, while he activated it, despite knowing that thousands of innocent people within that area will be killed along with the Daemonites.
  • Wild West COW Boys Of Moo Mesa: Skull Duggery, despite only appearing in the episodes "The Legend of Skull Duggery" and "Skull Duggery Rides Again", is one of the vilest villains to appear in the show. Skull Duggery was originally a old miner, by the name of Tom Duggery, who staked a silver claim and was too greedy to share it with anyone. He died in a cave in, but his ghost continued to haunt the mine. Marshall Moo's Kid Sidekick, Cody Calf, and 2 other kids go to the mine to look for the silver. Skull Duggery catches them, traps them in a mine shaft and fills it with water, attempting to drown the children. Marshall Moo saves the kids and causes another cave in, sealing Skull Duggery in his mine. However Skull Duggery escapes a year later. Obsessed with revenge against Marshall Moo, Skull Duggery recruits 2 other ghosts to help him. Skull Duggery plans to use a magic spell that rapidly ages everything, people and buildings alike, to destroy Cowtown.
  • Winx Club:
    • The Ancestral Witches, real names Belladonna, Liliss, and Tharma, are the first witches in existence and some of the first evil beings in the Magical Dimension. Under the orders of their master Lord Darkar, the Witches launched an attack across the Magical Dimension which reduced heroine Bloom's home planet Domino to a frozen wasteland, with its petrified inhabitants dragged into the Obsidian Dimension where the Witches torture them. The Witches are also responsible for wiping out the city of Havram to force its king, Erendor, to avoid conflict with them and condemned the souls of the deceased to constantly wander the ruins. The Witches attempt to capture the reincarnation of the Flame Dragon, Bloom, who was just a baby, forcing her elder sister to sacrifice her life to save her. The Witches are also terrible parents, viewing their son Valtor as useless and eventually transforming him into a mindless monster to use as a tool to destroy the Magical Dimension. Ultimately, the Witches plan to wipe out positive magic to rule supreme.
    • Season 2: Lord Darkar himself, the Shadow Phoenix, is the Greater-Scope Villain of the series. Born from the void as the Flame Dragon's opposite, Darkar launched an attack on the Magical Dimension with the goal of destroying it, including ordering the the Ancestral Witches to attack and devastate Domino. Defeated and sealed, Darkar plots to steal the Relix Codex to gain ultimate power. He captures Pixies to learn the location of the Codex, torturing them and their friend Aisha by draining their magical powers. After learning that the Codex has been split into four pieces, he frees Trix from their imprisonment to serve him and captures and tortures Altea's new professor Avalon for months while placing his spy in his place. Darkar successfully obtains all the pieces of the Codex and brainwashes Bloom into being his minion while banishing Trix to the void since he doesn't need them anymore. When her friends come to rescue her and stop Darkar, he almost kills them all before condemning Bloom to die with her friends after she breaks free of his control.
  • Xcalibur:
    • Kwodahn is the demonic mastermind of all evil in the story. Originally a Shogi Monk who turned evil to gain power, Kwodahn began bargaining with potential villains and evildoers to fully back their plans in exchange for their souls. Allying himself with the depraved Prince Bragan, Kwodahn uses every trick up his sleeve to ensure Bragan's rise to power and the elimination of all his foes. Kwodahn's crimes range from granting Bragan armies of demons he uses to slaughter opposing armies, to unleashing a soul-devouring demon onto a province, to later trying to turn an entire city into statue-like zombies. His evil not limited to mass murder and corruption, Kwodahn once sought the sword of Excalibur, and, when the noble Prince Erwann refused his request, Kwodahn first tried to kidnap the man's infant daughter, before settling for murdering his wife for rejecting him. When Bragan is beaten and all their plans ousted, Kwodahn murders Bragan then tries to corrupt and turn the young Arthus into becoming his new servant, before finally flying into a rage and unleashing his forces onto the entire kingdom with orders to kill every living thing they come across.
    • Prince Bragan is the brutal, sociopathic Regent of the kingdom who rose to power thanks to allying with Kwodahn. Murdering his own brother, King Erwann, to ascend to Regent, Bragan immediately begins manipulating his child nephew Arthus into becoming nothing more than a figurehead, while Bragan rules the kingdom with an iron fist. Driving villages to starvation, massacring entire temples, and torturing his foes being regular atrocities of Bragan's, he also frames Prince Edwin and his daughter, Djana, for murdering King Edwin, and constantly tries to execute Djana and her friends in various cruel methods, along with many attempts at slaughtering entire villages they have taken up residence in. Once failing to poison Arthus and claim the throne for himself, Bragan eventually hands Arthus to Kwodahn to with as he pleases, before trying to strike down his partner for ditching him in exchange for Arthus.
  • Xyber 9: New Dawn: Machestro is the Evil Overlord of the Machina, and the orchestrator of all evil in the series. As the Man Behind the Man to King Renard, Machestro supplies him with all the resources and technology he needs to keep his war with the heroic Queen Tatania going, resulting in Terrana's current wasteland state, and even supplies him with a city-destroying rail gun to destroy as much of Tatania's kingdom as possible. Causing droughts, famines, and overall chaos throughout Tatania's forces with his plans, Machestro uses the ancient Hunter Claw robots to lay waste to entire cities and set crops aflame out of spite. Seeking to claim the Xyber 9 so as to blanket Terrana in never-ending darkness, then lead a full scale annihilation of the human race, Machestro tricks the Machina as a whole into believing that they are unable to live in sunlight to keep them under his thrall. In the end, Machestro tries to use the Eye of Darkness to cause an unending night, either unaware or uncaring about the fact that it will result in the deaths of all living things, himself included. Machestro was a sociopathic warmonger obsessed with total domination, and would doom the entire planet due to nothing but his own arrogance.

Alternative Title(s): Adult Swim, Cartoon Network

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