- Multiplicity is a live-action movie example.
- The Matrix Reloaded: Smith begins cloning himself over other denizens of the Matrix after Neo does... whatever he did to him at the end of the first movie. By the end of Revolutions, he's turned every inhabitant of the Matrix into himself.
Agent Thompson: You!Smith: Yes, me. (hand-stab) Me, me, me.New Smith: ... Me too.
- In The Prestige, Angier uses the Tesla Machine, an electric duplicator/teleporter to create a perfect copy of himself to perform his "Transported Man" magic act. It's never established if the copy is created a distance away from the machine, or if the original is teleported but an exact copy is left behind. Since the trick involves killing the one left in the device, Angier never knows if he's killing an exact copy of himself for the trick, or if he kills himself each night and the copy continues on.
- Non sci-fi example: Blofeld's army of doubles in Diamonds Are Forever.
- In Asterix And Obelix the Druid multiplicates the eponymous duo to repel the Roman invaders.
- Penny the cheerleader in Sky High is the entire cheerleader squad. She ultimately turns out to be one (or several?) of the Big Bad's allies.
- Being John Malkovich: There's a door into John Malkovich's head that allows people to see through his eyes and (with experience) control him. When Malkovich goes through the door himself, he finds himself in a room where everybody has his head (including the women) and can only utter "Malkovich" to communicate.
- In Resident Evil: Extinction, Alice, teams up with a large number of clones of herself, with the intention of going after Umbrella.
- Multiple-Man's superpower in X-Men: The Last Stand.