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Anime & Manga
- In Katekyo Hitman Reborn!, Tsuna becomes afflicted with demonitis. The cure is its opposite, angelitis.
- The Green Lantern Corps includes a sentient smallpox virus, Leezle Pon, who fights off the evil Sinestro Corps virus Despotellis.
- Chimera (virus) and Bellerophon (cure) in Mission: Impossible II. Named for a monster from Greek Mythology and its slayer. This is justified, as those are actually their codenames for the project that created them.
- Subverted in Escape from L.A.: Virus: Plutoxin 7. Cure: Nothing, it's just a common flu virus; Snake is tricked into believing otherwise.
- Orson Scott Card's descolada and recolada viruses in the Ender saga. They translate as "un-glueing" and "re-glueing" because of their effect on DNA.
- Snow Crash and Snow Melt.
- Not a virus, but in Charlie and the Great Glass Elevator, the sequel to Charlie and the Chocolate Factory, there is a pill called Wonka-Vite which makes people younger. The cure for those who are aged too young — that is to say, out of existence, which happened to the Oompa-Loompas he tested the prototypes on — is a Rapid Aging liquid called Vita-Wonk.
Live Action TV
- The Revelation computer virus and the cure Faith in the game Uplink.
- Resident Evil has: T-Virus/Daylight Vaccine (because in the daylight, you don't need an umbrella); G-Virus/DEVIL; Las Plaga/Las Plaga Removal Lazer.
- From the Metal Gear series, there's FOXDIE and FOXALIVE.
- Deus Ex: Gray Death, cured by Ambrosia.
- Also, the "good" AI Daedalus and the "evil" AI Icarus. And they merge to form...Helios.
- Starcraft: Brood War: Hyperevolutionary virus, cured by Infestation Antidote
- Snatcher gives us a backstory where "Lucifer-Alpha" ravages eastern Europe, but mutates into a benign form by the present day. SD Snatcher follows more in line with the trope with "Lucifer-Beta" (the New and Improved virus) and "L-Angel" (the antidote).
- Old-school hackers had a taste for the dramatic that actually made this sort of thing reasonably common, e.g. "Creeper" vs. "Reaper".