- The Game: A 2006 sports/comedy/drama TV series.
- The Game: A 1997 film starring Michael Douglas.
- :the game:: An online Flash-based Deconstruction Game.
- The Game: Penetrating the Secret Society of Pickup Artists: A book by Neil Strauss about picking up dates.
- The Game: The seventh book in the Mary Russell series.
- "The Game": An episode of Stargate Atlantis.
- The Game (1984): A 1984 horror film.
- The Games: A 1970 film about the Olympic Games.
- The Game: The eighth studio album by Queen, released in 1980.
- The Games: A Mockumentary series about preparations for the 2000 Olympic Games.
- The Game: A memetically-popular mind game where the goal is not to think about The Game. Which you just lost.
- Big Game: A sports story trope for the climactic face-off between the protagonists' team and the Opposing Sports Team, almost always coming Down to the Last Play.
- The Game: A rapper from Compton, California.
- The Game: A Death Note Crack Fic.
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