[[quoteright:350:[[Website/{{Cracked}} http://static.tvtropes.org/pmwiki/pub/images/28157_895.jpg]]]]

->''"Science never solves a problem without creating ten more."''
-->-- '''George Bernard Shaw'''

Most writers are not scientists. Whether it is because they perceive science as cold and emotionless, or because they just disliked science and embraced literature [[WritersCannotDoMath after failing math in high school]], [[LuddWasRight luddism]] is an [[StockAesop awfully common philosophy]] in the arts community.

The [[HarmonyVersusDiscipline typical theme]] is that some sort of advanced scientific research has GoneHorriblyWrong, [[TurnedAgainstTheirMasters creating a monster]], causing an [[ApocalypseHow impending natural disaster]] and/or a [[GovernmentConspiracy massive government cover-up]]. The heroes typically discover the [[PsychoSerum side-effects]] of the research and investigate, discover what's going on, and try to stop it.

The antagonist (almost always either [[MegaCorp corporate]] or military/government scientists -- and [[BeautyEqualsGoodness not]] [[HotScientist hot]]) [[TheyCalledMeMad refuses to believe]] that his work could be so badly [[ScaleOfScientificSins flawed and/or immoral]], or simply doesn't care about [[ReluctantMadScientist who gets hurt by it]], insisting that the research is ''ForScience'' They will generally use their influence with the government to make life difficult for the heroes; this can include trying to have them arrested and/or [[MurderIsTheBestSolution otherwise]] [[TheCoronerDothProtestTooMuch silenced]], often leading to a shoot-out, jail break, or ChaseScene.

In the end, the scientist will be [[KarmicDeath destroyed by his own creation]], the heroes will be proven right, and through their efforts the world will be saved from the horror of science. Sometimes the theme is softened by the presence of TheProfessor among the heroes who represents a more reasonable take on the science involved.

Sometimes the problem is much closer to real-life evil done in the name of science, such as the scientist PlayingWithSyringes or [[TheyWouldCutYouUp performing invasive, deforming and/or deadly experiments]] on [[TestedOnHumans unwilling subjects]].

This can often come off as a bit hypocritical, particularly when dealing with speculative fiction, as you get an {{Anvilicious}} message of "everything we have so far is good, but we should stop now".

Nearly every RobotWar story is based off of this (except the ones where everything was all right, until humanity [[HumansAreTheRealMonsters screwed it up by being jerks]] to the nice robots). There are a few popular current fields as well, like [[CloningBlues cloning]], [[GeneticEngineeringIsTheNewNuke genetic engineering]], and [[SinisterSurveillance surveillance]].

For obvious reasons, this is played down in series starring a ScienceHero, heroic android, or RobotBuddy, such as in some anime. It's more likely that there will be a (still obvious) distinction between good and bad scientists. This is usually played up if the heroes are {{Phlebotinum Rebel}}s, though.

Note that not every work with a MadScientist or a threat borne of science falls under this; it's only the case where [[TheseAreThingsManWasNotMeantToKnow Messing With Things You Ought Not To]] is blamed for the problems.

The trope rarely makes a distinction between pure science (research) and applied technology (engineering).

Frequently overlaps with GreenAesop. May be paired with IndustrializedEvil.

Compare and contrast CyberPunk, where the rebel hero goes up against TheMan who maintains control through technology; BioPunk is mostly same as previous but instead using [[OrganicTechnology Biotechnology]] to retaining control of all species and used horrific ways to modify them; PostCyberPunk tends to embrace [[NewTechnologyIsEvil new technology]] less [[CrapsaccharineWorld critically]]. Typically, you will find there is NoTranshumanismAllowed. See also HarsherInHindsight and SeinfeldIsUnfunny for when a world meant to be portrayed as a {{Dystopia}} TwentyMinutesIntoTheFuture bears a curious resemblance to [[LifeImitatesArt present day]] technological advancements that are [[LostAesop taken for granted]] by the audience.

If the writer is sincere in their belief that NewTechnologyIsEvil, they may thrust the characters into a situation (ClosedCircle, AfterTheEnd, etc.) where they must survive without [[ScavengerWorld (most of) the technology]], and take the good with the bad; compare SpaceAmish. The inverse of this is a CozyCatastrophe, where the heroes are able to get General Motors, police and [[BeautyIsNeverTarnished hair salons]] up and running again only a few months after AmericaSavesTheDay, with [[ThrowawayCountry similarly unfortunate]] implications on the [[NoEndorHolocaust opposite end]] [[SpaceWhaleAesop of the spectrum]], implying that the writer believes in the [[StatusQuoIsGod Status Quo]]. {{Zeerust}} can have a similar effect if an otherwise futuristic (or even [[InformedAttribute "dystopian"]]) technocratic society bears a curious resemblance to [[WriteWhatYouKnow when it was written]] and problems the society was experiencing at the time.

Any time this trope shows up, you are very likely to find RomanticismVersusEnlightenment in its wake (and the work will be taking the Romanticist side). Related tropes include the MadScientist, ReluctantMadScientist, TheEvilArmy, GovernmentConspiracy, CorruptCorporateExecutive, [[TheGovernment Government As Villain]], MrExposition, TechnicalPacifist, and WellIntentionedExtremist. The protagonist is often assisted by an AntiHero who used to work for the MadScientist, and frequently has to deal with a PointyHairedBoss. See also ScienceIsWrong. Polar opposite of most stories with a ScienceHero.

Can be paired with the old slogan "Knowledge is Power, {{Wisdom}} is for serving". When the trope is invoked, Power is bad at best, evil at worst.

See also the ScaleOfScientificSins as well as AmbitionIsEvil. Not to be confused with DoNotTryThisAtHome when Science is Dangerous, cause yeah, [[StrawmanHasAPoint sometimes it is.]]



* The [[AnAesop Aesop]] of ''Anime/BlueGender'' is that humanity should never have advanced beyond an agricultural society.
* Averted in ''Anime/EarthMaidenArjuna''. Technological civilization is not an intrinsically bad concept, it's just gonna have dire consequences if you keep using artifacts and processes that are harmful to Earth's ecology. Devastating storms, droughts, infectious disease and the poisoning of the human body are presented through a more immediate, pro-active threat in form of invisible worm Kaijuus.
* ''Manga/NausicaaOfTheValleyOfTheWind'', at least in the manga version (which goes longer than the anime), goes back and forth between playing this trope straight & subverting it. On the one hand, the world was destroyed in a nuclear war, on the other, [[spoiler:the kindly & wise BigCreepyCrawlies were actually created through bioengineering and so were the giant killer fungi which are actually helping to purify the Earth. Nausicaa believes that the natural order of life should prevail and that humanity needs to live or die without the benefits or burdens of the old technology.]]
* The main conflict presented in ''Anime/{{Steamboy}}'' is that though scientists try to help the world there will either be [[CorruptCorporateExecutive people who want to use it for profit]] or people who want use it for war. The protagonist's father is under the belief that science can save the world, the grandfather believes he is going too far, and the protagonist is neutral and just wants to make sure London doesn't get destroyed. In the end, though, the moral of the story feels more like 'science can be bad or good depending on how it's used.' Take for example the Steam Castle, which was [[spoiler: not originally a weapon, but the world's most advanced amusement park.]] Then there's Ray's numerous clever uses of the [[MacGuffin Steamball]], like powering flying machines. At the very least, Steamboy manages to avoid being {{Anvilicious}} by grace of sheer ambiguity.

[[folder:Comic Books]]
* ''Franchise/{{Superman}}''
** ComicBook/LexLuthor, Superman's archenemy, has long been a barometer of the great bogeyman of the era: from the 30s through the atomic age, as a mad scientist he played on readers' fears of science run rampant. (Later, he'd be a corporate shark in the '80s and a corrupt politician at the turn of the millennium.) Though from UsefulNotes/{{the Silver Age|OfComicBooks}} until the Comicbook/{{Crisis|OnInfiniteEarths}}, Superman himself was portrayed as a scientist of great ability (having, at the very least, perfect recall and access to Kryptonian tech), regularly building robots and whatnot. His standard lament to Luthor in those days was his wish that Luthor would go straight and use his brilliance to help mankind instead of being a JerkAss.
** Space travel research was banned on Krypton. [[SubvertedTrope As a result, there were very few survivors when the planet exploded]]. Pre-Crisis, at least, the reason it was banned was that an illegal rocket experiment had recently blown up one of their moons. [[note]]Causing this catastrophe is why Jax-Ur is in the Phantom Zone.[[/note]]
* ''[[http://www.superdickery.com/the-only-hero-protecting-you-from-science/ Hoverboy: The Only Hero Protecting You From Science!]]'' However, Hoverboy is merely an [[StealthParody elaborate hoax.]] Probably.
* ''Franchise/StarWars''
** Subverted by the [[ThoseWackyNazis obvious Mengele analogue]] in a [[BadassNormal Boba Fett]] comic, in which Fett accepted a challenge to wipe out the crew of a [[strike: Nazi]] Imperial [[strike: flying concentration camp]] genocide ship. The Mengele-wannabe is asked by his boss what experiment he's doing; Wannabe admits, "I gave up all pretense of science long ago. I do this for pleasure."
** In ''ComicBook/KnightsOfTheOldRepublic'' there was a Mandalorian MadScientist named Demagol who conducted cruel experiments on captured Jedi and on children (including ''his own daughter'') in an effort to imbue future generations of Mandalorian warriors with the ability to use TheForce. His name was later adapted to "demagolka", the only word in the Mandalorian language for "war criminal".
* [[Comicbook/FantasticFour Reed Richards and Doctor Doom]] can be viewed as symbolizing technology's potential for good or evil, depending on who is wielding it and for what purpose. Reed's a perfect example, as he's often portrayed as the most cold and calculating of the ComicBook/FantasticFour. For instance, during the [[Comicbook/CivilWar superhero civil war]], he designed an extradimensional prison camp to hold his fellow superheroes because cold logic told him that forced superhuman registration was the only way to avoid an Armageddon-level disaster. None of the less scientifically-minded members of the team could stand to be a part of it, and Sue - the conscience of the team - eventually convinced him that it was better to essentially be nice and hope for the best than to be mean for a good reason. Taken even further in Comicbook/UltimateMarvel, where [[spoiler:Reed has a full fledged FaceHeelTurn and de facto becomes the new Ultimate Doctor Doom.]].
* ''Comicbook/ArchieComicsSonicTheHedgehog'' originally averted this in the same fashion as [[WesternAnimation/SonicSatAM SatAM]], from which it derived most of its cast. However, the series started to sink into this as early as Knuckles' first mini-series, with his race's flip-flopping stance on how to view science (It's evil, it must be destroyed! No, wait, only certain things is evil! No, wait, it's all evil! No, wait, it's evil unless we're the ones with it!)

[[folder:Fan Fiction]]
* In ''Fanfic/HalfLifeFullLifeConsequences,'' the "Combines" come from science and outer space. And science also makes [[spoiler: Gordon Freeman]] tricked and live and strong and big. However what the fan fiction calls "science" is debatable, since in many cases, it is referred to as a tangible object.
* In Act I of the ''[[Fanfic/TheEquestriaChronicles Legends of Equestria]]'' continuity, the main villain is an industrialist who uses his talents to invent new forms of munitions and weaponry. [[spoiler: He also tries to [[MoralEventHorizon murder Celestia, Luna, all their friends, and about half the population of Equestria to get on the throne]]]]. After these events, Celestia goes so far as to ''explicitly'' declare that technology is evil, and strictly bans its proliferation.
* Any pro-Equestria [[Fanfic/TheConversionBureau Conversion Bureau stories]], particularly the ones by the ''very'' divisive author Chatoyance, have the ponies declare technology evil and the reason why HumansAreTheRealMonsters. Anti-TCB stories such as ''Fanfic/TheConversionBureauTheOtherSideOfTheSpectrum'' have addressed that the ponies' own use of technology makes this sentiment very [[StrawHypocrite hypocritical]].
* Mr. X's attempted clone of Mew in ''FanFic/{{Pokeumans}}'' was what caused the genetic shockwave that kicked the plot off. It also drove him mad and turned him into a Mewtwo, which didn't help either.
* {{Inverted|Trope}} in ''Fanfic/TheLastRingbearer''. Mordor is a democratic, highly-enlightened, technology-using ''human'' civilisation, and they're the good guys. The Elves, meanwhile, are a bunch of smug, genocidal pricks who want to conquer Arda, enslave or exterminate humanity and stop all progress forever. [[WrittenByTheWinners The whole point of the work is an examination of the War of the Ring from Mordor's point of view]].

* Inverted in ''Film/{{Avatar}}''; the scientists are all good guys and it's through the scientific approach that they realize they shouldn't interfere with Pandora's ecosystem. The Na'vi goddess is also a real being, fully examinable and explainable through science. The bad guys are the military and corporates who misuse technology. The movie does ''not'' suggest that humans should shift back to hunter-gatherer culture like some supporters and detractors believe. In fact, the supplementary material is pretty adamant that scientific advancement is the only way to rescue Earth from its miserable state, and that research from Pandora is vital to this progress. The message is that aboriginal peoples should not be forced to adapt modern lifestyle against their will, and that horrible consequences caused by environmental exploitation can't be fixed with more exploitation.
* The original ''Film/TheFly1958'', contrary to popular belief, wasn't so much this trope as 'Science must not be approached with carelessness'. It even compares it to a 'great adventure'. In Creator/DavidCronenberg's [[Film/TheFly1986 1986 remake]], this motif is absent altogether: just because it went disastrously wrong ''once'' doesn't mean that teleportation is irredeemably evil. Though the original still features the scientist destroying the machine at the end, rather than seeing that it works fine if people aren't careless like he was.
* Completely turned around by ''Film/{{Darkman}}'', who, admittedly, was hideously deformed in a FreakLabAccident, but the accident in question was caused by TheMafia. When things are going bad, he reminds himself, "I'm a scientist!"
* ''Film/{{Expelled}}'' [[GodwinsLaw explicitly compares evolutionary biology to Nazism]].
* Inverted by ''Film/TheBeastFromTwentyThousandFathoms'', where blunt force ''could'' kill the rhedosaurus, but it spread the beast's disease far and wide, and only our heroic scientist can figure out a way to kill the rhedosaurus ''and'' the disease. Luckily, and [[TheEvilArmy unusually]], the army guys are extremely cooperative.
* In the BMovie ''Film/{{Bats}}'', MadScientist Dr. [=McCabe=] initially justifies creating the rampaging super intelligent omnivorous bats with the words "I'm a scientist! [[ForScience That's what we do!]]". No one finds this explanation even the slightest bit strange.
* ''Franchise/{{Godzilla}}''
** Averted in [[Film/{{Gojira}} the original]] in which sane scientist Dr. Serizawa's Oxygen Destroyer ultimately kills Godzilla at the end. Serizawa is also very careful ''not'' to let his invention fall into the wrong hands by [[HeroicSacrifice dying alongside Godzilla]] and [[NoPlansNoPrototypeNoBackup burning all papers that contain information on the device]].
** He's only concerned about the wrong hands in the American version. In the original Japanese version, Serizawa makes no distinction between right hands and wrong hands, saying that humanity's destructive nature will cause the Oxygen Destroyer to become our very undoing if ''anyone'' gets a hold of the device.
** ''Film/GodzillaVsDestoroyah'' retroactively questions the use of the Oxygen Destroyer by revealing it led to flesh-eating microbes that can strip organic matter immersed in water in seconds. These evolve into car-sized monsters spewing beams that disintegrate materials that possess oxygen molecules. And finally, ''these'' combine into, quite naturally, a flying Kaiju monster with a beam weapon that can kick Godzilla's ass.\\
The monster verges on raising the radiation levels of the entire planet beyond what life could survive. It also questions whether the doctor's sacrifice was actually heroic as the Oxygen Destroyer was, compared to other methods, less likely to destroy cities or attempt to exterminate the human race.
** Played straight in ''Film/GodzillaVBiollante'' in which genetic engineering causes the birth of a giant Godzilla-Rose hybrid monster (Biollante) with a human female soul. On the other hand, the scientists creating the Anti-Nuclear Bacteria is an aversion since it actually is one of the few things that can stop Godzilla, despite the hero's fear that it will create another monster.
** Generally played straight with almost any Godzilla movie that explains the eponymous monster's origins or his reason for attacking. Most often he is the result of the testing of nuclear weapons, which is also the source of his [[TurnedAgainstTheirMasters hatred of humankind]].
* ''Film/BrideOfFrankenstein'' inverts this. The reformed Dr. Frankenstein is forced by evil MadScientist Dr. Pretorius to return to his old ways. The twist: Early on, Pretorious shows us his collection of tiny humans in glass jars, practically announcing that he's Mephistopheles. To this, Frankenstein replies, horrified, "This isn't science!" Here, sane Science Is Good, and has standards, but Magic Is Bad.
* ''Film/EventHorizon''. At one point the inventor of the gravity warp drive (which turns out to be a pretty evil warp drive) proclaims: "Captain, there's no danger... It's contained behind three magnetic fields, it's perfectly safe!" Oh science, what are you like?
* In ''Film/GIJoeTheRiseOfCobra'' nanotechnology is the primary villain, both as gray-goo-inducing nanite warheads and as nanite injections that create superhuman flunkies for [[BigBad Cobra]]. There are many scientists involved in Cobra, and apparently, scientists can't be trusted: [[spoiler: Rex [[FaceHeelTurn switches sides]] because they have nanotechnology]].
* ''Film/TheTimeMachine2002''. Near the start of the movie, the protagonist's friend asks him whether humanity's progress will ever go too far; the protagonist replies, "no such thing."\\
He later has to admit that he was wrong -- when, in the future, he sees ''the Moon shattered into little pieces'' [[SciFiWritersHaveNoSenseOfScale by atomic bombs]]. Earlier, when the protagonist returned to the past to try and save his girlfriend, she was killed by a malfunctioning automobile (just as the protagonist stopped being fascinated with it because it was "just a machine," and not worth taking his attention off of his love).\\
In the distant future, the Eloi are peaceful, good people with very primitive technology; the evil, ugly Morlocks have an industrial society BeneathTheEarth. They also have a BigBad with a giant brain who is especially good at engineering, and at being evil.\\
And in the climax of the movie, the protagonist destroys the industrial Morlocks -- by blowing up his machine in their lair (commenting on its loss with, again, "it's just a machine"). The only positive portrayal science or technology get in the film is with the generally helpful [[ProjectedMan holographic librarian]] (who [[RagnarokProofing somehow survives hundreds of thousands of years]] and is shown reading books to children at the end). But his main function is to keep memories of the past (and, presumably, its follies) alive, not to represent or aid progress.\\
The [[Film/TheTimeMachine1960 1960 version]] doesn't go this far, having more of an anti-war message. Essentially, the 1960 film's message is "science is bad when it's being used to build bigger and more terrible weapons, but it's good when it's being used for peaceful, idealistic purposes like inventing time machines" -- which makes sense when you consider the movie was made at the height of the UsefulNotes/ColdWar arms race.
* ''WesternAnimation/{{Nine}}'' averts this. Science is what created the construction robot, but it was the government and military that put it to evil use. The scientist who created the robot then [[spoiler: sacrificed his own soul so that life, in some fashion, could carry on.]]
* Dr. Carrington in ''Film/TheThingFromAnotherWorld'' is a complete moron who continues to insist in the face of increasingly overwhelming evidence that the alien the base is dealing with is an intelligent and peaceful being, and repeatedly endangers everyone's lives trying to communicate with it.
* In ''Film/RockyIV'' the cold, emotionless Russian boxer Ivan Drago is shown training in a cartoonishly high-tech facility that measures his every exertion while government technicians look on, meanwhile virtuous American Rocky trains on a farm by cutting down trees, lifting bales of hay, and running with a yoke on his shoulders. Guess who wins.
** Also a case of ScienceMarchesOn as it turns out the techniques used there are not as effective as traditional training. Right now most sports training is the traditional ways mixed with a scientifically calculated diet and time table.
* Pick a Film/SyFyChannelOriginalMovie, any Film/SyfyChannelOriginalMovie. The plot is as follows: "Oh noes! Science Is Bad and inevitably results in giant insects! Explosions are the only thing that can rectify the wages of man's hubris! Better call Creator/JohnRhysDavies, Creator/LanceHenriksen, Bruce Boxleitner and/or Creator/DeanCain."
* The first ''Film/{{Mimic}}'' film plays this awfully straight. In order to combat an epidemic that's killing the world's children, scientists create a strain of mutant cockroach. Unfortunately, years after they're released (and successfully end the epidemic) these cockroaches grow to be about six feet tall and able to mimic (and eat) humans. Cue the scientists babbling nonsense lines like "We changed their DNA, we don't know what we did!" and other characters repeatedly saying what basically amounts to "They tampered in God's domain." As if the scientists should have foreseen the consequences of their mutant cockroach strain and done nothing to end the epidemic in the first place.
** In fairness, one critic of what they did ''does'' admit there was no other way, and that their actions in combating the disease saved his grandchildren from a grisly death.
* At least RIFT seems to think so in ''Film/{{Transcendence}}''. The head of the group uses the first brain uploading experiment which involved a monkey on why brain uploading is evil. "It just screamed."
* Like many late-1990s horror movies, ''Film/DeepBlueSea'' takes place in an elaborate science base where research is being conducted to [[CureForCancer cure society of some uncurable ill]] -- in this case, degenerative brain disorders. Lead researcher Susan has genetically modified mako sharks in order to increase their brain mass to harvest more protein, and the sharks get bigger and smarter and start killing everyone when they get into the base. It also takes another common position in this particular sub-genre, which essentially boils down to: Well, since the monsters created by science are chasing ''us'' right ''now'', every part of the research was bad in the first place. Screw those Alzheimer's patients! Bonus points for the two non-science people being the only survivors.
* In ''Film/PerfectCreature'', this view is held by [[OurVampiresAreDifferent Brotherhood]], the theocratic vampire government who had outlawed genetic research, regarding it as a godless, abominable evil. They withheld its progress to prevent humans from figuring out where vampires come from, how to prevent them from being born and gaining independence.

[[folder: Folk Lore]]
* The American folk tale of John Henry tells of the man's victory in a hammerin' race against a steam-powered hammer. He wins, but the effort kills him. He dies with the old-fashioned hammer still in his hand.

* In the first two books of the ''Literature/{{Divergent}}'' series, most of the bad guys come from the Erudite faction, the faction for scientists and knowledge-seekers. Many of the Erudite characters that we see are villainous [[spoiler:even Caleb turns out to be a traitor]]. Most of the bad things that happen in ''Divergent'' and ''Insurgent'' (e.g. the Abnegation Genocide) are a result of the devious scheming of the Erudite leadership, and it's implied they have a hand in corrupting members from other factions to their cause. [[http://veronicarothbooks.blogspot.com/2012/08/on-erudite-anti-intellectualism-and.html Even the author admits her book's anti-intellectual slant, though she has rightly pointed out that her portrayal of the Erudite became more nuanced, and even positive as the series went on]].
* Jonathan Swift rams this Trope down the reader's throat in the Laputa chapter of ''Literature/GulliversTravels''. The rulers are tyrants (and [[PoliticallyIncorrectVillain chauvinists]]) who respect only science, but it has made them [[TheCaligula incompetent rulers]]; while they are fond of mathematics, astronomy, music and technology, they fail to make practical use of their knowledge. For instance, buildings in Laputa are poorly built and the clothing doesn't fit because they take measurements with instruments such as quadrants and a compass rather than with tape measures. Their [[EvilMakesYouUgly physical conditions have degenerated too]], depicted as becoming so lost in thought that they do not move unless struck by a "bladder", many of their heads have become stuck reclined to one side, and they often suffer from strabismus: one eye turns inward and the other looks up "to the zenith". They don't even know that their wives [[YourCheatingHeart are adulterers]] who are using their husbands' lack of attention to carry on affairs with the more loving servants. Even worse, they've had a negative effect on their subjects. Not only are Lagado and Balnibarbi poverty-stricken, the governor of the former visited Laputa once, and was inspired to build the Academy of Projectors, where completely worthless projects are endlessly worked on. (Ironically, [[OnlySaneMan the governor of Balnibarbi]] is likely the most lucid man in the chapter, one of the few characters Gulliver meets with any common sense.) of course, Swift was using this chapter to mock - [[{{Satire}}among other things]] - the absurd inventions of [[https://en.wikipedia.org/wiki/Royal_Society the Royal Society]].
* This is ''not'' the point of ''Literature/{{Frankenstein}}''. In the novel by Creator/MaryShelley, the point of the story is that Frankenstein brought a creature into the world and allowed it to turn to evil by treating it like a monster. However, this ''is'' the point of every film adaptation of the story, which almost always deliver an {{Anvilicious}} [[AnAesop Aesop]]. With the surprising exception of the Creator/MelBrooks parody ''Film/YoungFrankenstein'', in which the eponymous scientist succeeds where his ancestor failed by accepting his creation like a loving father. When a group of his colleagues recoil in horror at the creature, he admonishes them "We are not children! We are scientists!", and the only real flaw in his creation (its permanently child-like, limited mind) is fixed by ''another'' scientific procedure, which Frankenstein risks his life to carry out. Stephen Jay Gould wrote one essay as a good-natured correction to people who thought ''Frankenstein'' was based around this, pointing out that while Shelley admits that being too excessive in a pursuit is usually a bad thing, ''all'' her examples were ''political''.
* In Creator/AnneMcCaffrey's ''[[Literature/DragonridersOfPern Pern]]'' novels, some of the natives regard the newly rediscovered supercomputer as evil and try to destroy or discredit it, either through superstition or fear of change. The planet was originally settled by people who only wanted to leave their ''dependence'' on technology behind, not to form a Luddite civilization. In time this meant they lost all but the most basic stuff needed for survival, and because of this they suffered. It was eventually ''returning'' to the technological state which saved them, when they found AI which gave them access to all the tech the colonists planned on having, but lost.
* ''Literature/TheLordOfTheRings''
** The trope is played straight in the opposition between Saruman (Science/Knowledge) and Gandalf (Wisdom). Saruman even mentions his slogan in book two: "''Knowledge, Rule, Order''!" All the while, Gandalf warns against swerving from the "path of Wisdom". Saruman is clearly meant to be a Faustian figure, entering a {{deal with the devil}} for greater knowledge.
--->'''Gandalf''': He that breaks a thing to find out what it is has left the path of wisdom.
** Tolkien himself was personally fond of the trope, and invokes it in "Literature/TreeAndLeaf", and in his poem "Mythopoeia":
-->The dark abyss to where their progress tends, if by God´s mercy, Progress ever ends...
** And then there is Aulë, Vala (i.e. "archangel" of sorts) of all makers, craftsmen, and scientists (Sauron and Saruman were both Maiar under him).
* Creator/HPLovecraft goes a step further, though it's [[FantasticAesop not just science]]; H.P. Lovecraft's stories had a recurring theme that [[ThingsManWasNotMeantToKnow ''wanting to know more about the world'']] would inevitably lead to insanity and corruption. Lovecraft had a love-hate relationship with science. On one hand he was delighted and inspired by its discoveries, but on the other he found it horribly formulaic and unimaginative (complaints he also had about mainstream religion). His short story, ''Silver Key'' sums up his less than flattering thoughts towards ''all'' forms of mainstream thinking.
* ''Literature/OryxAndCrake'' has more than a hint of this.
* Every book by Creator/MichaelCrichton, [[MisaimedFandom a good deal of which got a lot of people interested in science]]. Crichton himself averts this trope in that he was a big ''proponent'' of science and more science education. Chrichton's point is generally more along the lines of: science is good if used for something like feeding people or helping the sick, i.e. something benign and obvious. But like anything one must also have the common sense to use it with ''restraint''. Being "pro-science" is one thing, not having the two brain cells needed to stop and say "Gee, I wonder if something could go wrong if we genetically engineer dinosaurs?" is another. Also to note, in most of his novels, what is decried is not the science in and of itself, but rushed science used for no other reasons than to make a quick buck. Find a way to clone dinosaurs? Make a theme park. Finds a way to time travel? Use it to make a theme park. Find a way to make nanobots autonomously intelligent? Use it to get results you can sell faster.
** While Crichton's characters seem to be either Lampshading this trope or living up (down?) to it, if you pay attention, it's really ''Big Business'' and its irresponsible use of scientific discoveries that is bad, not science itself.
* In ''Literature/MaximumRide'', no scientist character is ever good and nothing science ever accomplishes is ever for the good.
* ''The Birthmark'' by Nathaniel Hawthorne concludes with the [[AnAesop aesop]] that [[spoiler:people shouldn't attempt to play God by improving on nature]]
* In the novel ''Literature/{{Feed}}'' by M.T. Anderson, having essentially an internet hookup directly into your brain lets you look up anything instantly, so no one ever bothers to really learn or remember anything, becoming imbeciles with the attention span of gnats.
* This is one of the main messages of ''Ceremony'', along with "White people are evil beings created by witcherey to destroy the world''
* ''Literature/TheWarOfTheWorlds,'' has a touch of this. [[Creator/HGWells Wells's]] Martians are clearly designed as his projection of what man himself might evolve into, given enough time: little more than bodiless brains, helpless if separated from their machines. Wells may have viewed this fate as inevitable for mankind.
* Although most of his later novels were much more pro-technology, Creator/JulesVerne's early novel ''Literature/ParisInTheTwentiethCentury'' portrays a cold, sterile future where artistic and humanistic pursuits have been all but abandoned in favor of technology as an answer to all human problems. The main character, a poet, can find neither work nor sympathy, and [[spoiler: dies starving in the streets]].
* This tends to be a characteristic of many Creator/StephenKing novels, including his magnum opus (the Franchise/TheDarkTower series). We have
** The Great Old Ones from the Dark Tower series, who are explicitly described as being "deceived by the false light of science", replacing the magic with their own imperfect science and technology, then killing themselves off with weapons that leave the world a polluted, ruined mess.
** [[ThePlague The superflu]] from ''Literature/TheStand''. which escapes a government lab and kills off 99.4% of the world's population--the creators designed it to make sure an antivirus could never be made. The mini-series implies that Flagg may have had a role in the release of it, but the book itself describes it as a series of foul-ups and technical errors. Flagg is specifically described by [[WriterOnBoard Glen Bateman]] as "the last magician of rational thought" (!) and he gives an impassioned defense of the concept that they should not be so quick to recreate the technological civilization that created things like nukes and bio-engineered germs in the first place.
-->'''[[TheHero Stu:]]''' ''(of [[MagicalNegro Mother Abigail]])'' Well, it's obvious she's some sort of [[DreamWeaver magnet]].
-->'''[[TheMentor Glen:]]''' So I suppose we start building the whole sorry mess up again... using her as [[FakeUltimateHero magnetic north]].
* In the words of Jean Baudrillard in ''The Procession of Simulacra'', "Science never sacrifices itself. It is always murderous." He didn't think science was inherently bad, despite that quote.
* In the last ''Literature/EmpireFromTheAshes'' book, the world religion of the planet Pardal centers entirely around the suppression of scientific progress, [[CargoCult while at the same time worshiping an ancient defense computer as the voice of God]].
* In the Literature/{{Safehold}} series the need for the deliberately LostColony to revert to a pre-industrial technology level to avoid the omnicidal Gbaba was an unfortunate necessity. WordOfGod is that this trope is part of the thinking behind Langhorne and Bedard's alteration of the original plan to make sure that a technological society doesn't arise again.
* Most movie versions of H.G. Wells' ''Literature/TheTimeMachine'' (as stated in the Film section) emphasize the evils of technology versus a pastoral existence, but neglect his central thesis: [[AnAesop the alienation of the working class resulting in an elite that neither knows nor cares how the comfort in which it lives is produced]]. Wells, a socialist, was not arguing against technology but against the exploitation of the working class in Victorian England. Indeed, most of Wells' body of work, especially ''The Shape Of Things To Come'', is very ''pro''-science and technology, focusing more on how humanity must mature socially in step with its scientific progress.
* In AleksandrMazin's ''TimeForChange'' duology, nature itself follows this trope, with catastrophes striking out against many types of scientific research in a seemingly unrelated manner. For example, the first recorded catastrophe was a massive tsunami that flooded New York. The link was an attempt by [=NASA=] to see if it is possible to give birth in orbit. After that, the International Committee for Prevention of Illegal Scientific Research ([=AKA=] Aladdin) is created in order to enforce the ban. They recruit the scientists and soldiers and equip them with the latest technology allowed by law. They become so powerful that only a few nations can go against them, including Russia, China, and possibly US.
** In the second novel, ''The Morning of Judgment Day'', the Chinese defy the ban and launch a manned mission to UsefulNotes/{{Mars}}. During a historic speech televised throughout the world, another catastrophe hits, causing any Chinese-speaking person listening to the broadcast to go deaf. The protagonist's father parallels this to the Tower of Babel part of Literature/TheBible, where man attempts to reach the heavens, and suggests that humans may have to stay on Earth for good.
* ''Literature/TwentyThousandLeaguesUnderTheSea'': The book show us both sides of this question: In almost all the book, TheProfessor Aronnax, a WideEyedIdealist expert on marine life is shown all the good things the [[CoolShip Nautilus]] can accomplish (scientific discoveries, exploration of the South Pole, treasure hunting, etc). Only after TheReveal, that the Nautilus is used as a terrible (for the standards of the 19th century) WeaponOfMassDestruction, Aronnaxís HeelRealization lets him know that those good things canít justify the terrible violence.
* The 2nd and 3rd ''Literature/{{Dinotopia}}'' books were quite {{Anvilicious}} about this, although they were more anti-technology than anti-science, since the protagonist himself was a scientist (although more of a naturalist, really).
* ''Literature/TheTripods'' used this, but as a pretense of the antagonists rather than an actual theme of the work. The Masters gave the appearance that they blamed science and technology for humankind's evilness, thus pushing humanity back to the middle ages with the Caps. (ie sending the ScienceIsBad message through the caps.) It was really to stifle creativity and independent thinking and make humans easier to subdue.
* In the 1990 extended edition of ''Literature/{{Nightfall}}'', a scientist tells a priest that he's proven how the apocalypse his religion predicted would come to pass[[note]]a previously undetectable moon eclipsing the one sun out of six visible on the darkest day of the year, which occurs every 2049 years and drives everyone mad because of species-wide Nyctophobia[[/note]]. The priest throws a fit because the scientist "[[MeasuringTheMarigolds destroyed the mystery]]" or somesuch.
* In Larry Niven's ''Literature/KnownSpace'' books, all scientific research on Earth must be approved by the government. Violating this can result in a death sentence.
* Played with in ''Literature/AmericanGods''. The New Gods represent different facets of America's modern, technologically advanced culture, but for a while we are led to sympathize more for the primitive -- and seemingly more benevolent -- Old Gods. Over the course of the story, however, we come to learn that a not insignificant number of the Old Gods were violent, bloodthirsty monsters in their time, and some of the New Gods are [[DesignatedVillain not as eager for conquest as they first appear]].
* In ''Literature/ThoseThatWake'', after seeing what technology did to the city, Laura grows to believe science is bad by the second book.
* ''Ape and Essence'' has a sequence symbolically representing WorldWarIII, in which three Albert Einsteins are enslaved by [[ManiacMonkeys baboons]] for the patriotic purpose of developing and unleashing {{Synthetic Plague}}s that kill everyone, including the Einsteins, whose dying protests are that they "never did any harm to anybody" and "lived only for Truth." Thus is enacted "the death, by suicide, of twentieth-century science."
* Isaac Asimov's ''Literature/TheEndOfEternity'' is basically a rejection of this trope, essentially arguing that progress -- even that which seems dangerous -- is vital and necessary to us as a species.

[[folder:Live Action TV]]
* ''Series/{{Smallville}}''. Any scientific research is bad in that show. Example: One episode features a drug which can heal fatal gunshot wounds in moments. However, it makes the user rather cranky for a certain period of time. Various [=ER=]s could probably get around that by tranquilizing the patients for a while!
* A recurring theme in ''Series/TheOuterLimits1995''. It is the basis for the plot of many (though not all) of its episodes. A prominent episode, "Final Appeal" involves a trial in the TwentyMinutesIntoTheFuture United States, which has forsaken technology and banned teaching science under the penalty of death. A 20th century scientist develops TimeTravel and goes to the future only to be arrested for breaking the ban. She goes before the Supreme Court and argues to repeal the ban, as a plague will wipe out most of humanity in the near future if technological research is not restarted. Another time traveler arrives to argue for the opposite, as humanity's expansion to the stars will eventually cause us to piss off an advanced alien race and lead to our destruction. In the end, they send the second time traveler to the past and agree to repeal the ban, only for the second guy's fusion bomb to activate and wipe out Washington, DC.
* Creator/JossWhedon has said the idea behind the Initiative from ''Series/BuffyTheVampireSlayer'' was to create a conflict between science and magic, and when that happens, magic eventually kicks science's ass. The Initiative goes on recon to study the habits of vampires and captures them so they can do further tests, all to [[DoingInTheWizard better understand how they work and how they can best be contained]]. Buffy just stakes 'em. Guess which works better?
* ''Franchise/StarTrek'', despite being the best-known SpeculativeFiction series, often dipped its toe into this trope. Worked on a sort of sliding scale, where the level of science the Federation had at that particular point in the episode was the exact right amount and trying to advance beyond that was just asking for the technological equivalent of [[CantGetAwayWithNuthin not being able to get away with a damn thing]]. Offscreen advance of science: good. Onscreen advance of science: bad.
** ''[[Series/StarTrekTheOriginalSeries The Original Series]]'' episode which most directly addresses this is "The Way to Eden" (the infamous "space hippie" one). Dr. Sevrin's followers want to abandon technology and return to a pastoral existence. Between his Vulcan half's admiration for their (ahem, [[TechnicalPacifist technical!)]] pacifism, and his human half's submerged longing for exactly that sort of simple life, [[RoundedCharacter Spock]] of all people ends up sympathizing with them. He's deeply disappointed when their leader turns out to be nuts.
** ''[[Series/StarTrekVoyager Voyager's]]'' take on the [[SufficientlyAdvancedAlien Q]] is interesting. ''[[Series/StarTrekTheNextGeneration TNG]]'' had previously established that the Q believed humans might one day develop into a civilization comparable to themselves (and were [[FantasticRacism not very pleased about it);]] yet, in ''Voyager'', most of the all-but-omnipotent Q are shown to be bored half out of their minds, because life offers no challenges any more.
** Averted in Roddenberry's novelization of the first [[Film/StarTrekTheMotionPicture movie,]] which claims that most of humanity outside of Starfleet is actually going a transhumanist route, forming into massminds and such. Kirk, as narrator, regards this as a generally good thing and chides himself for being old-fashioned. However, this claim [[CanonDisContinuity is not supported]] anywhere else in Trek canon.
** In TOS, BunnyEarsLawyer Sam Cogley's speech in "[[Recap/StarTrekS1E20CourtMartial Court Martial]]" about liking his book collection better than his computer, even though he admits it can display any of their contents instantly.
** The TOS episode "The Ultimate Computer" is a great example of this trope, combined with a little LuddWasRight. The ''Enterprise'' is testing a brand-new computer that could automate starships completely, making crews and captains all but obsolete. AIIsACrapshoot, things go south fast, and our heroes must pull the plug and save the day, but not before the sorrowful moments where Kirk faces the thought he may become obsolete. The scientist who designed the computer also turns out to be insane at the end, just to drive the point home.
** In the [[Series/StarTrekDeepSpaceNine DS9]] episode "Paradise," the neo-Luddite colonist Alixus deliberately stranded her colony ship and used a [[{{Technobabble}} duonetic field]] to disable electromagnetic technology, forcing them all to live as SpaceAmish. Her influence over her fellow colonists was so great that even after Sisko and O'Brien disabled the field generator and revealed that she had stranded them there deliberately, many of the colonists wanted to continue living the way she had preached (or very near to it, perhaps making exceptions for medical technology).
*** The episode in many ways was a deconstruction of this trope. None of the characters entirely disagree with or refute her claims that there is value in doing things the hard way rather than living comfortable lives with "modern" Federation technology. Instead, they condemn her actions and methods for forcing this lifestyle on others as deplorable: deliberately stranding the colonists (instead of recruiting like-minded volunteers), deceitfully sabotaging any technology, invoking corporal punishment (solitary confinement in a hot-box for any violation of her rules), and withholding life-saving medical technologies (resulting in unnecessary suffering and many deaths).
*** Contrasted with the "Sons of Mogh" in the episode "Children of Time", in which a group of alternate-timeline descendants of Worf (some by blood, others in "spirit") choose to live as pure hunters/warriors, foregoing any technology more advanced than spears or bows. This (voluntary) group is portrayed as everything ''good'' about the NobleSavage archetype, peacefully coexisting with their technology embracing neighbors and even trading with them for what few necessities they require beyond their own capability to produce.
* ''Series/{{Fringe}}'' seems to take a stance of science being both bad ''and'' good, since its used to both cause ''and'' help solve the Freaky MysteryOfTheWeek! The GreyAndGrayMorality of the show seems to imply that science can accomplish good things, but at the cost of other good things, and the scientist's [[YMMV/{{Fringe}} mileage may vary]] as to whether the accomplishments are worth the cost. This is especially obvious when comparing and contrasting Walter and Walternate; each crosses lines that the other will not. For example, Walter is willing to experiment on children while [[WouldntHurtAChild Walternate is not]], but Walternate is willing to trap people alive in amber while Walter is not.
* While the ''Franchise/{{Stargate}}'' series mostly avert this, the ''Series/StargateAtlantis'' episode "Trinity," wherein [=McKay=] finds an abandoned Ancient experiment to produce limitless energy, it's repeatedly suggested that he is getting in over his head (The Ancients did not complete the program, and it went rather wrong). Despite constant protestations that this is a field they are simply not ready for, [=McKay=] continues. In the end he ends up destroying about five-sixths of a solar system (it's not an exact science). While the episode plays the aesop straight, a later episode has a solution to the problems from the first time, and the attempt is assisted by an Asgard, the most technologically advanced race who will talk with humanity.
* On an episode of ''Series/{{CSINY}}'', this trope is used to demonize the science of Genetics. It starts off with a supposed dead man being stolen from the back of the van that was bringing it to the morgue. Then the body is dumped in the river, fished out and then found to be alive... brain dead, but alive. They find their way to a genetics research lab that's making goats produce silk in their milk and rats grow ears on their backs. The scientist in charge explains the benefits of it (silk in bulk, replacing a lost body part) but the cops just remark about how weird it is and when they leave remark that it's wrong. The main character going so far as to say progress was great, "but should've stopped."\\
Turns out the genetics lab induced human hibernation on the victim, which the victim was involved in voluntarily and by accident the vic took too much of the mixture they created too fast. He ran out choking and collapsed. They stole him from the van thinking he was alive, thought he was dead when they couldn't revive him and dumped him before they got in more trouble for their unethical experiments. When confronted by this news the head scientist can only remark about his delight that it worked and lists off all the benefits like prolonged space travel and how he will be famous.\\
The second suspect tries to tell the cops how putting them away will "shut the door on the future" as [[NoPlansNoPrototypeNoBackup no one else knows the formula but them]], but to the cops the complicated issue is simple, they committed attempted murder (even though they thought the guy was already dead) and are going to jail. It's not "robot apocalypse" or "mutant monster" worthy, but it still denotes the same thing: science is weird... and bad.
* ''Series/EleventhHour'' generally runs on this trope, as should be expected of a show about a duo that takes down people who apply new technology unethically. However, it does at times depict the potential good that can be done with stem cells, genetic engineering and the like.
* Most of ''Series/{{Battlestar Galactica|2003}}'' avoids this, but the finale takes a great big swerve into WriterOnBoard territory. [[spoiler:First, everybody decides to chuck their technology -- including, one assumes, their various medical advances -- and revert to hunter-gatherer barbarism in the hopes that their descendants will do better. Have fun rediscovering penicillin a couple hundred thousand years in the future, humanity! Second, Ron Moore confirms that, after a thoughtful examination of how difficult it is to break the cycle of revenge, he chucked the metaphor and explained that [[http://www.nj.com/entertainment/tv/index.ssf/2009/03/battlestar_galactica_ronald_d.html he's scared of our new Japanese robot overlords]].]]
* An episode of ''Series/TheColbertReport'' featured Stephen interviewing the author of a book about robots and AI. The author pointed out that the West is largely wary of AI (see ''[[Film/TwoThousandOneASpaceOdyssey 2001]]'') while the East (especially Japan) generally sees AI as a positive thing (see ''Manga/AstroBoy'').
** Stephen often says things like "I'm no fan of science," but seemed entirely keen on one specific form when hearing about a superlaser that concentrated laser beams into a small area to produce the temperatures and pressures of a star:
---> '''Stephen''': ''We have our own [[Franchise/StarWars Death Star!]]''\\
''(Cue rain of black balloons and a big "WE HAVE OUR OWN DEATH STAR" sign flashing in the foreground)''
** Stephen Colbert's views on science can be summed up as this. Cool Science = Good, Boring Science = Bad.
* An inversion in an episode of ''Series/{{Sliders}}'' the gang ends up sliding to a world where all new technology was banned after the end of UsefulNotes/WorldWarII. This world's version of Quinn was killed by polio, and they convince Quinn's dad that technology is not bad and would have saved his son. He helps them to repair their timer with his dead son's illegal technology. The local Evil Corporation decides to steal the timer as they have been creating technology in secret so they can corner the market once the ban is lifted.
* Dark Science Empire Deathdark, the villain group of ''Series/DaiSentaiGoggleFive'', revolve around using science for evil things. It's also informed that they helped the invention of sword so it can be used to kill. Ouch.
* ''Series/{{Lost}}'' played with this trope with Dharma Initiative being the "we will do it no matter what" side. Taken to the logical conclusion in season's 5 finale [[spoiler: where they continue to drill over a pocket of electromagnetic energy, although they know that in-universe EM is a [[ArtisticLicensePhysics bad, explosive thing]]]].
* This is the basic philosophy behind the Consortium in ''{{Series/Eureka}}''.

* The entire ''01011001'' album by the metal opera group Music/{{Ayreon}}. See the song "Unnatural Selection" for a particularly {{anvilicious}} example.
* Music/SystemOfADown's "Science" from the album ''Music/{{Toxicity}}'' is entirely devoted to explaining in detail how ScienceIsBad and has "failed us," as "spirit moves through all things." [[HypocriticalHumor Performed on electric instruments.]]
* Music/{{Styx}}'s album ''Music/KilroyWasHere'' includes some brief diatribes, not against science per se, but against technology:
-->The problem's plain to see\\
Too much technology\\
Machines to rule our lives\\
Machines dehumanize.\\
-- ''Mr. Roboto''
* Music/TheAquabats' song "The Cat with Two Heads!" is about a scientist who creates the eponymous two-headed feline, only for it to escape from captivity and go on a vengeful rampage against its creator.
* The song [[http://www.justsomelyrics.com/1897771/Red-Guitars-Good-Technology-Lyrics Good Technology]] by Red Guitars doesn't necessarily condemn technology, but does lampshade its absurdities and moral ambiguities. The last verse sums it up:
-->Sometimes I wonder what it is all about\\
There's lots of leisure time to sit and work it out\\
There's a TV show I've got to see\\
Good, good, good, good, good, good technology\\
Good technology
* Ultimately subverted in Sepultura's ''Biotech Is Godzilla''.
--> Bio-technology ain't what's so bad
--> Like all technology, it's in the wrong hands
--> Cut-throat corporations don't give a damn
-->When lots of people die from what they've made
* The song "La concubine de l'hemoglobine" ("The concubine of Hemoglobin") by French rapper [=MC=] Solar: unbridled science entails war and wholesale destruction:
--> Science sans conscience (science without conscience)
--> egale science de l'inconscience (equals science of the unconscious)
--> Elle se fout du progres mais souhaite la progression (it cares not of progress but wishes the progression)
--> De tous les processus qui menent a l'elimination (of all processes that lead to elimination)
* Nitin Sawhney's piece "Street Guru" features some random dude's bitchy platitutes over various things in modern life. On technology:
--> I think there's going to be a backlash against technology. You know, I don't know what's gonna cause it. I hope it won't be any environmental disaster shit, you know, for sure for my kids that wanna live a better life.... You know sometimes it's good just to go in the woods and just go hiking and get back in touch with yourself and nature. You know, then you come back here and you realize that this is like, better. Ludicious all this emphasis on technology and 50 different internet devices and shit and internet devices you can put in your pocket. Sometimes I feel threatened by it but you know, that's the future and I am a man of the past. I'm a low-tech man in a high-tech world there ain't shit I can do about it... You know, what's going on we can't use our brains: It's being a person. You know it's being a ''fucking'' person man!
* Zager & Evans "In The Year 2525."
* "Cursed Be Iron" by Turisas appears to condemn ''iron-working'', but is probably a metaphor for military technology or the misapplication of technology. It includes the demand that iron "[[YeOldeButcheredeEnglishe Come and view thine evil doings]]/ And amend this flood of damage", seemingly avoiding the idea that science or technology are ''inherently'' bad.
** The lyrics are lifted straight from a 1888 English translation of Literature/TheKalevala, [[http://www.sacred-texts.com/neu/kveng/kvrune09.htm Rune IX: Origin of Iron]], making this arguably OlderThanFeudalism. Taken in context, it's ''not'' about the evils of science or technology ''at all''.
* "White Coats" by New Model Army appears to fit this trope, although it can be interpreted as criticising science when practiced without foresight or ethics, particularly given that it was written during an apparently self-destructive [[UsefulNotes/ColdWar US-Soviet nuclear arms race]]- "Those last few days at Jonestown ain't got nothing on this ".
* "Internet Killed The Video Star" by The Limousines has a repeated lyric "The kids are disco dancing, they're tired of rock n' roll/don't bother telling them that drum machine ain't got no soul." Though, this appears to be less of an overt science diss, so much as commentary on the modern youth culture failing to give enough credit to yester-year artists and musicians.
* [[Music/InsaneClownPosse The Insane Clown Posse]]'s infamous song ''Miracles'' (about appreciating the majesty of everything around you) suddenly includes the lines "And I don't want to talk to a scientist/Y'all motherfuckers lying and getting me pissed," which makes the song sound more like it's accusing science of sucking the mystery out of everything.

* Subverted in a strange and depressing sort of way by Arch Oboler's ''Lights Out'' radio short [[http://thethunderchild.com/RadioDrama/LightsOut/TheChickenHeart.html "Chicken Heart"]] (as made famous by [[http://www.youtube.com/watch?v=3vPimtcK3-A Bill Cosby]]); the scientist responsible for creating the spreading, cancerous blob of chicken muscle knows exactly how to stop the monster, but he can't get the authorities to [[Film/{{Cloverfield}} drop the hammer]] in time or with enough force. [[spoiler: If only they'd known about the monster-retardant properties of Jell-O.]]

[[folder: Roleplay]]
* Averted in ''Roleplay/DinoAttackRPG''. While the main antagonists are a science-based organization, they actually started off with good intentions, researching [[EldritchAbomination the Maelstrom]] in an attempt to keep it from [[CosmicHorrorStory obliterating the universe]], and they only lost sight of their original goal when [[spoiler:the Maelstrom started controlling their leader; after Dr. Cyborg took over as their new leader, they returned to their original goal]]. Additionally, a large percentage of the Dino Attack Team consists of scientists including Einstein, Fuchs, Crusher, and Reptile, all of whom are "good" scientists whose research is beneficial to the team.

[[folder: Stand Up Comedy]]
* Parodied by comedian Patton Oswalt in his standup routine where he lambasts science for allowing a couple in their sixties to conceive due to it being horrifying, Ending with the line "Hey, we made cancer airborne and contagious. You're welcome. We're science, we're all about could, not should". This, however, is an exception in that quite a few of his other routines exalt the virtues of science and progress, however.
** Reversed in "Werewolves & Lollipops" when he and his wife are expecting and their friends advise a "natural birth" like the pioneers did it. Oswalt jokes about wanting the exact opposite, including a machine that helps greatly but kills every 1-in-100 infants during delivery.

[[folder:Tabletop Games]]
* ''TabletopGame/{{Warhammer 40000}}'' has a rather odd relationship with this trope. On one hand, anything resembling actual science is [[{{Understatement}} Strongly Frowned Upon]] by the settings closest equivalent, the Tech Priests of the [[MachineWorship Adeptus Mechanicus]]. The setting also happens to be home to examples of every category on the ScaleOfScientificSins. On the other hand, CyberneticsEatYourSoul and NoTranshumanismAllowed aren't in effect for a sizable portion of the setting, presumably due to the sheer [[RuleOfCool Coolness]] of cybernetics superseding the normally all-pervasive Rule of Grimdark.
** Another subversion, considering that the race that is arguably the closest to being the "Good Guys" (or, [[BlackAndGrayMorality all things considered,]] "least evil") of the setting, the Tau, are the only ones who embrace science and technological advancement.
* ''TabletopGame/MagicTheGathering'': Yawgmoth is portrayed as a rational-minded character who relies only on scientific methods, while others [[BlackBox rely on not better defined "magic"]]. He's the BigBad.
** Averted by other characters, however - Tocasia, Jhoira of the Ghitu, Venser of Urborg, Slobad of Mirrodin, and Arcum Dagsson are all extremely talented artificers, and all are unambiguously heroic. Urza was more...[[AntiHero on the fence about it]].
** Subverted by the set "New Phyrexia"; while the Blue-affiliated EvilutionaryBiologist scientists of the Progress Engine are evil and show many of the common traits of this trope, they are not any more villainous than the religiously dogmatic Machine Orthodoxy and the [[MeasuringTheMarigolds aggressively anti-science]] Vicious Swarm.
** Then there's Ravnica's Izzet Guild, where everyone is a MadScientist and explosions abound. The craziest member of the guild is also their most powerful member and founder Nivv-Mizzet, who also happens to be a ''dragon''. That said, the guild is just as vital to Ravnica as the other guilds, and none of the guilds are straight up good or evil.
* Creator/WhiteWolf's ''TabletopGame/WerewolfTheApocalypse'' and ''TabletopGame/MageTheAscension''.
** In ''Werewolf'', the [=PCs=] are shapechanging super-powered eco-terrorists.
** The Glass Walkers, a technophiliac tribe of the Garou Nation are held in contempt by most of the rest of the tribes, and called "urrah". And towards the end of the gameline, it shifted so fault for the world lay more heavily upon the Weaver, who was the one who drove the Wyrm mad and has plans to calcify all reality. The Glass Walkers are regarded by the other Garou tribes as hopelessly naive about the Weaver.
** In ''Mage'', it's not so much that technology is bad as it is that people are taught that technology is the only way; in this world, [[ClapYourHandsIfYouBelieve reality is what people believe]], and believing there's no such thing as monsters or magic goes a long way to protect humans from the aforementioned shapechanging super-powered eco-terrorists and other supernatural beings out to victimize humanity. Unfortunately, this leads to [[UtopiaJustifiesTheMeans giving up creativity and magic]]. Happily, as a counterexample proving that Science itself is not bad, we have the [[WeirdScience Etherites]] and [[PlayfulHacker Virtual Adepts]], and most members of the Technocratic Union (the main antagonists) are perfectly decent people who just happen to be on the wrong side from the players' point of view, and as they became playable, their views became more human and sympathetic.
** ''TabletopGame/ChangelingTheDreaming'' has a somewhat schizoid attitude towards science: it's the moon landing that opened the doors to Arcadia and allowed the Sidhe to return, but in general technology is seen as just chock-full of imagination-killing (and so changeling-killing) Banality, except maybe for the SteamPunk-ish gadgets of the Nockers.
** The BrokenAesop of the entire [[TabletopGame/OldWorldOfDarkness oWOD]] was that the creeds opposing "stasis", represented by the science that regularly changes the world, were heavily into hierarchy and hadn't changed in centuries.
** In the ''TabletopGame/NewWorldOfDarkness'', things have taken a step or two away. Werewolves still largely distrust technology, because it's done more to screw up the Shadow Realm than anything else, but they accept that it has a place and hold this version's technophile tribe, the Iron Masters, in better regard than their past counterparts. In fact, one of the ''antagonist'' Pure Tribes is given the "Luddites" [[PlanetOfHats hat]] (it's worth noting the Pure are ''very'' reminiscent of the Garou). Over in ''Mage'', things haven't changed as much; the Free Council, SpiritualSuccessor to the Virtual Adepts, are given short shrift largely because they're rather young and tend to make nuisances of themselves. However, science is no longer the primary tool of a WellIntentionedExtremist AncientConspiracy that may have JumpedOffTheSlipperySlope.
** The fanmade ''TabletopGame/GeniusTheTransgression'' certainly can give this vibe, but it's actually not an example since no comment is made on sane science -- or arguably an aversion, since the further a Genius' beliefs differ from reality (the one sane scientists are so busy documenting), the easier it is to slip into outright grave-robbing, god-defying, blood-splattered MadScience.
* Kicked in the balls by ''TabletopGame/CthulhuTech:'' the main reason why humans have a fighting chance is because science found a way to make Magitek and HumongousMecha.
-->'''Random Free Councilor:''' "Told you so!"
* Settings where CyberneticsEatYourSoul. Most of these worlds are CyberPunk [[WorldHalfEmpty dystopias]], so they often feature this trope in other ways, too.
* ''TabletopGame/SLAIndustries'', where it's probably impossible to count all the examples of "SLA tries to solve their problems by engineering a new breed of super-monster, but it goes nuts and [[TurnedAgainstTheirMasters turns against them]]".
* ''TabletopGame/{{Kult}}'', where "Victim Of Medical Experiments" is a viable Dark Secret for players. Oh, yeah, along with the fact that the growth of cities and technology is actually part of the breakdown of the illusion that is reality -- the illusion that's covering up the horrifying ''true'' reality underneath it.
* In ''TabletopGame/{{GURPS}} Traveller Interstellar Wars'' this is averted. The Terrans are excited about science because they like everything new. The Vilani are not interested in advancement but only because their ancestors deliberately decided that it was coming to a point of diminishing returns, not that they hated it in principal. Most of the sympathy is with the Terrans although the Vilani are not treated without sympathy despite the fact that the word Vilani sounds like villain. Both sides are Federations and the chief cause of the war seems to be mutual arrogance.
* In the original ''TabletopGame/DungeonsAndDragons'' "Known World" campaign setting (later renamed TabletopGame/{{Mystara}}), the ancient civilization of Blackmoor was technological, but destroyed itself in what is implied to have been a nuclear war. The Immortals decreed that this could never be allowed to happen again. However, they allowed one pocket of Blackmoor society to endure as a lost land in the Hollow World with the caveat that all of its simulated "technology" is actually magic based, and therefore impossible for its citizens to reverse engineer, reproduce, or improve upon.
* Parodied in ''TabletopGame/{{Paranoia}}''. Science is crazy, even when it's CrazyAwesome, and [[EverythingTryingToKillYou it's trying to kill you]].

* Steve Reich's "video opera" ''Three Tales'', an AuthorFilibuster-filled work that centres around the crash of the airship Hindenberg, the nuclear test at Bikini Atoll, and Dolly the cloned sheep.

[[folder:Video Games]]
* ''Videogame/LostOdyssey'' inverts this as technology is neutral and it's actually ''magic'' that's screwing with the natural order.
* Frequently a side plot of many ''Franchise/FinalFantasy'' games, though never played straight.
** Subverted in ''Videogame/FinalFantasyX''. The characters (and the population of Spira in general) spend most of the game thinking that the BigBad was created as punishment for bad science, only to find out that [[spoiler:it's actually magic gone wrong. They eventually defeat him with machines believed to be evil, instead of the religious ritual they were meant to use.]] By ''X-2'', both of the major factions (the Youth League and New Yevon) agree science is okay; their major disagreement is how quickly all of the previously-suppressed technology should be distributed and implemented into society (New Yevon being the more conservative faction).
*** It's also the reason that the Al Bhed are ostracised from society; they've always made heavy use of machina, and are the only ones to speak out against the idea of the [[AppealToTradition summoner's pilgrimage]], though this is mainly because of [[spoiler:the fact that the process ends up in the death of the summoner for what would only be a quick breather from Sin's malice]].
*** The Church of Yevon had as one of its core tenets that machina is evil [[spoiler:but since they knew the truth about Sin they had no compunctions against using it themselves. The very heart of their church in Bevelle is actually an advanced {{Magitek}} city in disguise -- the Bevelle temple makes use of machina transporters and their troops wield machina rifles and are supported by war machina.]]
** ''Videogame/FinalFantasyVII'' starts off seemingly with this theme, but introduces more nuance to it as the story goes in. On the one hand, many of the characters rely on technology and science to live and get by, particularly after the events of the game itself. But characters like Hojo, who experiments on people purely to satisfy his own ego, rather than benefiting humanity, and the rest of Shinra Inc. tend to abuse it. Also, the game's environmental message, and going back to a simpler, rustic existence was seen as favorable to an advanced one. However, Bugenhagan, the head of the most rustic settlement in the world, enjoys his ride on the Airship, calling the technology something akin to "the wisdom of man." When Barret, the leader of [[EcoTerrorist AVALANCHE]], meets a man living in a remote glacial house, he says if he were to live in nature like that he'd make it "more comfortable," then quickly realizes that's what technology is and has a brief NotSoDifferent moment about Shinra before quickly recanting. The real message doesn't seem to be that ScienceIsBad, but that Science needs to be used carefully.
*** It's also worth pointing out that Bugenhagen himself operates quite an advanced observatory and planetarium.
* Played with in ''Videogame/{{Okami}}'', where [[spoiler:[[GodOfEvil Yami, God of Darkness]] is implied to be the originator of Technology and is a MechanicalLifeform (albeit one with a seemingly organic core)]] as well as the fact that the demons Lechku and Nechku are robotic owls. However, Waka's Tao Troopers use {{Magitek}} computers and the [[{{Precursor}} Moon Tribe]] apparently do have some access to advanced technology. In fact, helping a mechanic with his research will give Amaterasu the power to summon lightning. Ultimately, it seems that Science and Evil don't exactly go hand in hand.
* ''VideoGame/{{Mother 3}}'' heavily suggests that the proliferation of technology would bring about the world's downfall, especially given how certain scenery transforms as the game progresses. Though it seems to hint more at an '[[{{Eagleland}} American culture is bad]]' message. Which is really ironic given how the first two games celebrated modern society and used the setting as an AffectionateParody of American culture.
** Other interpretations of Mother 3 suggest the game wants you to think this at first, but the message overall is less "science is bad" so much as "happiness is a fuzzy subject that can be defined and measures in a lot of different ways and both science and naturalism are one of many valid ways to achieve happiness."
* In ''VideoGame/{{Fallout 3}}'' the most prominent case is Doctor Lesko, a wannabe MadScientist who [[spoiler:created the fire ants that destroyed Grayditch]] in an experiment GoneHorriblyWrong. Despite this, the game makes it clear that Lesko is merely careless, not evil, and [[ScienceHero science-oriented players]] have the opportunity to lecture on him on proper experimental procedure.
** The ''VideoGame/{{Fallout}}'' 'verse has its share of good and evil scientists. Most "good" scientists adapt existing technology to try to rebuild civilization (such as the Project Purity and Rivet City teams). Scientists who use Forced Evolutionary Virus are depicted either as irresponsible or outright evil.
** In ''VideoGame/FalloutNewVegas'', Veronica, a member of the Brotherhood of Steel and a potential companion is frustrated that the Brotherhood only cares about recovering and preserving specific technology from the pre-war days, such as PoweredArmor and {{Energy Weapon}}s, but not develop new technology or find alternate uses for the stuff they have. Only one Elder insists on alternate avenues of research but his ideas are dismissed as insanity, mostly because he is the only Elder to gain his position via the Scribe route instead of Paladin. That and the fact that Elijah was a madman obsessed with obtaining technology no matter the cost and planned to use technology to enslave the Mojave (with his belief in obtaining non-military technology being portrayed as PragmaticVillainy).
** The New California Republic has scientists working round-the-clock trying to solve their power, food, and water problems.
** This is also one of the teachings of Caesar, who believe that technology led to the decadence of the old world, prohibiting any weapons that do not require infantry and medicine beyond tribal remedies (stating that those who depend on such are weak and deserved to be culled). [[spoiler:[[{{Hypocrite}} Caesar himself has an Auto-Doc for his brain tumor and is willing to take Arcade Gannon as a physician]].]]
*** Plus his disgustingly cruel methods and that absolutely everyone predicts that the Legion will destroy itself if it ever runs out of people to conquer.
** The DLC ''Old World Blues'' is based in functional pre-war research facility that is filled with experiments that are both extremely helpful and extremely cruel. Ultimately in the epilogue of the DLC your own Karma determines whether science is evil or not. (A good courier will use the facility for humanity's benefit, a bad one will use it for personal gain).
** ''VideoGame/{{Fallout 4}}'' generally continues the Science is Bad ethos of the franchise. The Institute, a hidden cadre of scientists descended from M.I.T and the people who create the [[ArtificialHuman Synths]], are generally considered to be the game's BigBad; given [[SlaveryIsASpecialKindOfEvil how they treat]] [[JustAMachine the Synths they create with almost no consideration for their rights]], it's really not hard to see how mostly people come to that conclusion. Meanwhile the most noble faction, the Commonwealth Minutemen, are a bunch of down-to-earth wastelanders with jury-rigged SchizoTech.
** One of your companions, the [[TokenHeroicOrc Super Mutant]] Strong, holds technology in disdain and disapproves of you hacking terminals or using Power Armor.
* ''Videogame/{{Crystalis}}'' takes place 100 years after a nuclear war ends civilization. Since then, the people have abandoned science in favor of magic.
* Similar to [[FanNickname "SatAM"]] ''WesternAnimation/SonicSatAM'' below is ''[[VideoGame/SonicTheHedgehogCD Sonic CD]]''. [[spoiler:Taking Robotnik and his robot generators out of the equation reveals a good future in which technology and nature co-exist harmoniously]]
* ''Videogame/{{Doom}}'' is based on the premise that teleportation is a literal contact with Hell. Half or more of the demons are cybernetically augmented. On the other hand, experimental weapons tend to save the day. In the third game, the company that develops the teleportation device is shown to have also created breakthroughs in energy generation and storage, and is in the process of terraforming Mars.
* Occurs a few times in the ''VideoGame/TalesSeries'':
** In ''VideoGame/TalesOfSymphonia'', all technology uses Exspheres, [[spoiler:which are PoweredByAForsakenChild]]. Furthermore, the BigBad turns out to have this view: for [[spoiler:it's revealed that he split the world into two in order to ensure that neither would have the Mana supplies required to develop weapons of mass destruction.]]
** While not exactly played straight in ''VideoGame/TalesOfVesperia'', the technology actually ''does'' have the unintended side effect [[spoiler:of summoning the Adephagos.]] As it turns out, in-universe, [[spoiler:all technology is actually powered by ''the souls of the Entelexeia, solidified and broken into fragments.]]''
** The BigBad of ''VideoGame/TalesOfGraces'' was once a [[ArtificialHuman humanoid]] who became a WoobieDestroyerOfWorlds [[spoiler:when the only scientist to treat him with love was secretly trying to turn him into Fodra's new Lastalia was killed by another scientist and her humanoids because her and her superiors saw Lambda as a threat because anything injected with his cells would become a monster.]]
** ''VideoGame/TalesOfXillia'' features Spyrix machines. "Natural" magic works by feeding Mana to Spirits and being granted their magic in exchange. Spyrix machines ''burn'' Mana as fuel to create magical effects, thus starving Spirits of their food source. [[spoiler:Spyrix were initially created to level the playing field between those who could use Spirit Magic and those who were biologically incapable of it. This offended the Lord of Spirits enough that he rounded up everything magical in the world and sealed them away in a separate world, forcing the survivors to rely even more on Spyrix to fill the massive magic-shaped gap in their civilisation. It tips the balance so badly that the Spyrix world is practically a wasteland by the time the protagonists visit it]]. Fortunately, the final act of the game has the protagonists use their scientific knowledge to research and develop a new technology that addresses everyone's concerns: [[spoiler:Spyrite technology]].
* This is Myria's viewpoint in ''Videogame/BreathOfFireIII''.
* There are good scientists in ''Videogame/CityOfHeroes''. They're just constantly over shadowed by people like [[MegaCorp Crey]], [[ThoseWackyNazis the 5th Column, The Council]], and [[PlayingWithSyringes Neuron]]. Oh, and Portal Corp, despite being a good organization, [[NiceJobBreakingItHero has caused way more harm than good]].
** There's also the enemy group called the [[ExactlyWhatItSaysOnTheTin Luddites]]. They live in the Rogue Isles and can be seen protesting Dr. Aeon's evil technology all over Cap Au Diable. As it turns out, [[spoiler: his tech [[CassandraTruth really is evil]], just not quite in the way they suspected.]]
* ''Franchise/ResidentEvil'': Science and evil are like best pals in the Resident Evil universe. Most, if not all, the troubles in the series are caused by groups of power hungry scientists who think it's a novel idea to use the T and G-Virus to create unstable monstrosities with a likelihood of things going wrong being above 105%. There is not one good scientist in the entire series and major villains like Albert Wesker and Alexia Ashford are the results of genetic engineering to create the ultimate super-being. Doubly so by the fact that the scientists who started the research and are responsible for all the horror, are also the founders and owners of the company, so they can't get away with the usual "the man used my work for evil" excuse.
* While ''Videogame/{{Spore}}'' doesn't go so far as to outright call science bad, it is notable that the Scientist archetype's special ability is the Gravity Wave, which instantly [[WorldWreckingWave wipes out all life on a planet]] and is one of the only two archetypes whose special ability breaks Galactic Code to use (the other being the [[EasyEvangelism planet-converting]] [[ScaryDogmaticAliens Zealot]]).
* In ''Videogame/AlphaCentauri'', the science-based faction of the University of Planet has an increased number of drones due to 'unethical research'. The fundamentalist faction also rails against the (unrighteous) use of technology, though their leader Miriam is not a Luddite, rather fearing that humanity will lose control of their creations.
-->'''Sister Miriam:''' The righteous need not cower before the drumbeat of human progress. Though the song of yesterday fades into the challenge of tomorrow, God still watches and judges us. Evil lurks in the datalinks as it lurked in the streets of yesteryear. But it was never the streets that were evil.
** In the novelizations, Miriam is perfectly willing to use advanced technology received (read: stolen) from other factions, such as the [[OneNationUnderCopyright Morganites]] and the University, be it using a genetically-engineered virus to wipe out the entire population of a base or putting quantum singularity generators into planet busters (super-nukes) and using them to level entire continents.
* In ''VideoGame/MediEvil'' this trope is referenced. When visiting the HQ of the evil wizard Zarok (your nemesis), which is full of {{Magitek}} and SteamPunk gizmos (from the Steampowered undead soldiers, through a Steam train in eleventh century England, all the way into Time Machines), one of the exposition-delivering Gargoyles mentions that Zarok has mastered "the darkest of all magics: Science".
* ''Videogame/MegaManStarForce 3'' Tia and Jack were both orphaned in war for the technology of their home. They join the Dealers and want to use Meteor G to destroy all the worlds technology.
* The Alliance-UN war central to the plot of ''Videogame/MissionCritical'' is sparked by fear of science going out of control after the first created [=AIs=] caused a university to be wiped out by a KillSat. UN imposes a ban on certain fields of research and demands that all of humanity abide by it. Several nations refuse, forming the Alliance of Free States. Interestingly enough, despite their fear of advanced technology, the UN SpaceNavy is much more advanced than the Alliance one.
* ''VideoGame/BatenKaitosOrigins'' sets itself up with this trope [[spoiler:and then subverts the hell out of it with the true villain of the story being a magic wielder. The ultimate moral seems to be that neither science ''or'' magic are bad, it's merely how people choose to use them.]]
* In ''VideoGame/{{Xenoblade}}'', the nature-based world of Bionis is invaded by the mechanical soldiers of Mechonis, and they are the main enemies of the game. [[spoiler:Until the third act, where it's revealed the Machina are [[WellIntentionedExtremist Well-Intentioned Extremists]], and the spirit of Bionis is the ''real'' villain, thereby [[InvertedTrope Inverting this trope.]]]]
* In ''VideoGame/GuiltyGear'', humanity was pushed to the brink of extinction in a brutal war with the titular [[HumanoidAbomination Gears]], who were created by scientists, [[spoiler:one of whom was Sol Badguy, the main character]], to be the next step in human evolution. Most nations (except Zepp) have outlawed conventional science and technology as "Black Tech" and replaced it with magic, [[HumansAreBastards although that eventually ends up getting abused by humans as well]].

* Brutally satirized in [[http://dresdencodak.com/2009/09/22/caveman-science-fiction/ this]] ''Webcomic/DresdenCodak'' strip.
** Now has a [[http://www.youtube.com/watch?v=cEChG1DKGvY live action version]]!
* This sentiment is expressed by some characters in ''Webcomic/GirlGenius'', given the damage that [[MadScientist Sparks]] are known to do (and many of the characters who think so were, indeed, casualties of Spark activity). One of these characters is Othar Tryggvassen ([[MemeticMutation GENTLEMAN ADVENTURER]]), a Spark himself, who decided to set off on a quest to eliminate the Spark from the world, ending with his own death, because he's keenly aware of how dangerous they can be.
** Can also be interpreted as a subversion by savvy readers: the spark is very much _not_ science, it's a blatantly magical force which no one but the original user can reproduce that coincidentally mostly produces physical objects which superficially appear mechanical. The few sparks who can treat the spark as actual science (that is, work out the principles, write them down comprehensibly, and explain them such that others can reproduce them) can be counted on one hand and are treated as problem-solvers of the highest caliber worthy of even enemies' respect: the Wulfenbachs, Van Rijin, and possibly the Storm King.
* ''Webcomic/MinimumSecurity'' is a very hard, left-leaning environmentalist comic that oftens takes pot shots at science. Many characters bomb labs and power plants while celebrating a world in which people remained agrarian.
* ''Webcomic/NoBlackPlume'' frequently parodies this, including a six-part series entitled "Science Will Ruin Your Life".
* An implied aversion occurs in Dr. Light's TheReasonYouSuckSpeech to Dr. Wily in the VideoGame/{{Mega Man|Classic}} sprite comic Webcomic/MSPaintMasterpieces.
-->'''Dr. Light:''' Open your eyes, Dr. Albert Wily! Haven't you had enough delusions of world domination? ''You lost'' because you don't understand the true potential science has for this world. Watch and learn.
* An in-universe view in ''Webcomic/TheGlassScientists'' is that science - especially mad science - is source of all evil. The main character's efforts focus on changing this outlook.

[[folder: Web Original]]
* ''Roleplay/InkCity'' has attracted plenty of scientists, including [[WesternAnimation/JimmyTwoShoes Heloise]], [[WesternAnimation/ElTigreTheAdventuresOfMannyRivera Dr. Chipotle Jr.]], WesternAnimation/{{Megamind}}, [=GLaDOS=] and [[VideoGame/{{Portal 2}} Caroline]]. There are also characters who want to use science to analyze and control the unpredictable residents, like [[WesternAnimation/AeonFlux Trevor]].
** [[VideoGame/{{Pokemon}} Mew]] believes that all science is inheritly evil, and that scientists are soulless monsters. Due to this, she sees nothing wrong with [[ColdBloodedTorture subjecting them to]] AFateWorseThanDeath.
*** Averted in the actual Pokemon canon where Mewtwo, who has far more reason to hate science, uses the same cloning technology that created him.
* The Rise of the Steam Soul from Wiki/TheWanderersLibrary, though it's not science per se.
* A short video by Ben Croshaw of ''WebVideo/ZeroPunctuation'' fame had a radio playing during ''VideoGame/HalfLife'''s train ride opening.
-->'''Radio:''' You're listening to Black Mesa Radio: We play the hits while you [[AGodAmI play god]].

[[folder:Western Animation]]
* Practically every episode of the first season of ''WesternAnimation/SuperFriends'' focused not on a villain but on a WellIntentionedExtremist, a MadScientist, or a regular scientist whose invention accidentally runs amok. An early episode had a scientist gain hyper-intelligence (and a cartoonishly enlarged cranium) due to some sort of radiation experiment, and rather than use his superior intellect to take over the world, decides to broadcast the rays so that ''everyone'' on Earth can enjoy the same radically evolved intelligence as him. Thank god the Justice League saved us from the horrifying fate of becoming smarter!
* Dr. Blight from ''WesternAnimation/CaptainPlanetAndThePlaneteers'' is the show's resident embodiment of the trope. Having said that, one Planeteer Alert encourages viewers to learn more about science, since science can be used for good.
* ''WesternAnimation/TheSimpsons''
** Parodied with the ignorant townsfolk going on an anti-science riot, including attacking the Museum of Natural History, with Moe smashing a mammoth skeleton, having it land on his back and crying "Oh! My back! I'm paralyzed! I only hope medical science can cure me!"
** Another episode showed a similar mob set to burn Principal Skinner at the stake for insisting that the earth revolves around the sun.
** In the episode "Bart's Comet", when the eponymous comet burns up in Springfield's polluted atmosphere instead of destroying the town as predicted, Moe shouts "Let's go burn down the observatory so this never happens again!" Cue the angry mob.
* Delightfully parodied in any episode of ''WesternAnimation/TheAngryBeavers'' where they feature B-Movie star Oxnard Montalvo. ([[DullSurprise "The crawling spleen has grown an opposable thumb, oh the humanity!"]])
* Averted in the ''WesternAnimation/SonicSatAM'' animated series. Even though the world has been conquered by [[EmperorScientist Dr. Robotnik]] with an army of MechaMooks and a machine that lets him inflict UnwillingRoboticisation on the victimized organics, despite the fact he is deliberately running his energy plants and factories inefficiently in order to poison the environment and weaken them, science in itself is not portrayed as evil. All of the blame is instead placed squarely on Robotnik being a power-crazed psychotic megalomaniac who is misusing and abusing scientific tools to enforce his own demented desires.
** The Roboticizer wasn't even ''his''. Uncle Chuck invented it as a means of keeping people with terminal illnesses alive until a cure could be found, or even as a means of eliminating amputation. When Robotnik came to power, guess who was the first one to get thrown into the Roboticizer...?
** Sally Acorn, co-protagonist, [[EverythingsBetterWithPrincesses Princess]], and {{Love Interest|s}}, also has her own [[RobotBuddy artificially intelligent handheld computer]] named Nicole, who is consistently helpful to our heroes.
* ''WesternAnimation/AvatarTheLastAirbender'' takes place during the Fire Nations industrial revolution, pitting nature vs science on the expected poles, as they are also environmentally harmful, which is also harmful to spirits. Science as a whole isn't treated poorly(positive examples include The Mechanist and Sokka), but its more often exploited by the Fire Nation, and the butt of some early jokes given the magical nature of the show.
* ''WesternAnimation/TheLegendOfKorra'' plays with this, the technology has advanced, and its portrayed as a good thing, cars and airships abound. Then the Equalist [[spoiler:with Hiroshi Sato as the Evil GadgeteerGenius]] unveil all new better technology with shock gauntlets, robots, and airplanes, in addition to the cars and airships. [[spoiler: Those planes are use to take down the bender army's {{Magitek}} battleships.]]
* Played straight in an episode of the CGI ''[[WesternAnimation/TheGarfieldShow Garfield]]'' series. The first half of the episode features Odie digging up a dinosaur bone, only to have the local museum threaten to get a court order evicting them from their home because "science is more important" the second part of the episode features a cleaning robot gone mad.
* In the ''WesternAnimation/TeachersPet'' movie, the BigBad says, "Nature is dead! Science is king!" [[StrawVulcan Science is the study of nature...]]
* ''WesternAnimation/TheAvengersEarthsMightiestHeroes'':
** While the show doesn't have this as a theme, Thor does have this opinion. [[InvertedTrope He's proven wrong.]] [[RunningGag Repeatedly.]]
** Captain America often chides Iron Man for his reliance on [[PoweredArmor technology]]. [[HypocriticalHumor 'Cause, you know]], it's not like ''his'' powers came from technology, or anything.
* ''WesternAnimation/TheTick'' parodies this trope in "Tick vs. The Proto Clown", in which a scientist who loves clowns theorized that a ''bigger'' clown would be even funnier, and his creation is now terrorizing The City.
-->'''Arthur:''' Good gosh, man. Didn't you know it was against the laws of nature? Clowns were never meant to be that big!
-->'''Scientist:''' [[GoneHorriblyWrong I know that... now...]]
* ''[[http://www.youtube.com/watch?v=PTdzCAGH3lU Invention of Love]]'' has {{Steampunk}} technology in a "too much of a good thing" sense. Mechanical horses? Awesome! A house full of appliances? Convenient! A polluted city without any natural flora or fauna? Throwing away the rose your true love gave you when it wilts ''[[UpToEleven and building a mechanical replacement]]''? ...not so much.

[[folder:Real Life]]
* Sadly common in some more conservative areas of the world, particular along the North American Bible Belt.
** Bill Nye, once having visited a small town in the Bible Belt to give a speech, came out to find his car defaced with the words "[[IncrediblyLamePun Bill Nye the Science Lie]]."