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Anime & Manga
- In One Piece: "The Tyrant Kuma is dead." He is now a Cyborg working for the World Government.
- The Mazinger franchise:
- Mazinger Z: This is Big Bad Dr. Hell's favorite trick. This is how he got himself his Co-Dragons. He found Brocken bleeding to death on the ground and turn him into a headless Cyborg. While exploring the underground mazes of Bardos he found two mummified bodies. One half of each body was crushed under rocks. So he sewed the intact halves together, revived it like a Cyborg with a mechanized brain and named it Ashura. And his Mooks? He -or his henchmen- killed people and he turned the corpses into cybernetic slaves programmed to serve him. Now you know what happened to all the people who died in the battles between Mazinger-Z and Hell's Mechanical Beasts.
- Great Mazinger: Ironically, Big Bad Physical God Emperor of Darkness did the same thing to Hell himself, turning him into his newest Dragon.
- UFO Robo Grendizer: The Vegans grafted brains of prisoners into their Saucer Beasts. Duke got a severe Heroic B.S.O.D. when he was told he technically had killed one friend of his every time he blew up a Robeast.
- In Afro Samurai, this is Kuma's backstory. After nearly being killed when Afro first got the Number 2 Headband back, he's brought back from the brink of death by Dharman and the Empty 7 after being turned into a cyborg-samurai.
- The Shitennou in the Sailor Moon manga were Endymion's Generals before everyone was sent into the future to be reborn and fight Queen Beryl in the future. Present day however, they've been brainwashed and now serve her as the Quirky Mini Boss Squad.
- She does this to Tuxedo Mask himself, having Kunzite kidnap him as Sailor Moon is revealed to be Princess Serenity. The irony being, just as she remembers her love for TM and his for her, he is kidnapped, brainwashed, and turned against her.
- It's also the main shtick of Kunzite in the anime version: turning civilians into Monsters of the Week to try and find the secret identities of the Sailor Soldiers, once doing this to Sailor Venus' best friend from London. Quite ironic, considering he's one of the Shitennou (who in the anime don't appear to have the same backstory as in the manga)...
- That's the origin of the Phages, the Monsters of the Week of the fifth season: as a side effect of having their Starseed extracted, people with a fake Starseed (that is, everyone but the Sailor Soldiers) become a phage.
- In the manga, the Daimons of the Death Busters are civilians (or, sometimes, cats and dogs) who had their souls removed and replaced with beings from the Tau Star System, transforming them into monsters at random times. Note that this is when the process fails: successful Daimons keep a human appearance.
- While the anime used objects as the vessels of the Daimons, we still have two similar examples: Germatoid uses professor Tomoe as host in the anime before leaving him near the end of the season (where in the manga Germatoid was Tomoe after becoming a Daimon), while a Daimon in Sailor Uranus' and Neptune's flashback was a kid who assumed the form of a failed Daimon.
- Almost everyone in Blassreiter, especially when XAT almost entirely was infected with Pale Rider. Some managed to remember themselves and turn on their would-be "masters" anyway, but most were taken over completely.
- Naruto: Madara Uchiha does this to Obito Uchiha, turning him into Tobi.
- In Tekkaman Blade, every Tekkaman is an example. The Radam captured a bunch of explorers and subjected them to a harrowing procedure that infused them with awesome superpowers and a parasite controlling their thoughts. Takaya aka D-Boy's father used the last of his strength to free Takaya and interrupted the process. As a result, Takaya had the superpowers of a Tekkaman but lacked the mind controlling parasite, but at the cost of going berserk if he stayed transformed too long, possibly because the process was interrupted prematurely.
- One of the Sequel Hooks of Tokyo Ghoul involved Aogiri's plans to do this, using captured Ghoul Investigators for use in hybridization experiments. These plans come to fruition two years later, when Seidou Takizawa makes their very bloody debut as Aogiri's new Owl. Formerly the Plucky Comic Relief for the human-focused chapters, he performed a Heroic Sacrifice trying to protect Amon and was written off as killed in action by his superiors. Driven insane by experimentation and torture, he turns out to be completely aware of his past and hints at a feeling of resentment over being abandoned by his superiors. His inferiority complex has been used to twist him into a vicious killer, encouraging him to seek out and try to kill Sasaki to prove himself superior to his predecessor.
- In Digimon Frontier, when Big Bad Cherubimon is unable to recreate/find a Digimon to wield the powerful Spirits of Darkness, he instead snatches up a wandering human (or rather, the human's ghost/astral projected soul), brainwash him, and force him to take the Spirit instead, creating the terrifyingly powerful Duskmon, who comes damn close to wiping out the season's Digidestined. Unfortunately for Cherubimon, the human he snatched turned out to be Kouichi, one of the heroes' long-lost brother, and that lingering connection keeps him from killing the heroes long enough for them to orchestrate a Heel–Face Turn.
- Horsemen of Apocalypse in X-Men, particularly Archangel/Death.
- Psylocke was long thought to be this after she returned from Japan transformed into a psychic ninja assassin. The truth turned out to be a bit more complicated.
- All of the heralds of Galactus are this.
- Incredible Hulk: Back in The '90s the Leader used the dead body and mostly dead brain of Thunderbolt Ross to power the Redeemer armor.
- This is the M.O. of supervillain Deathmonger in Empowered, as he is a necromancer.
- This is what happens to Bucky Barnes, former kid sidekick to Captain America. He's brainwashed by Soviets and turned into the Winter Soldier, an elite killing machine.
- In the New 52, this was, ultimately, how Harley Quinn became a villain; The Joker brought her to the factory where his own transformation had occurred, and forcibly dunked her into the same vat of chemicals, with similar results. (Probably the biggest reason why Harley is far more insane in this version than previous ones, often just as much as he is.)
- Child of the Storm has the classic example of the Winter Soldier.
- HERZ: Combined with Grand Theft Prototype due to the semi-organic nature of the Evas. After Shinji subdued the MP-Evas in 2015, NERV rebuilt them, mind-wiped them and reprogrammed them to serve them.
- This is the SOP of all the Succubae in The Return, both the protagonists and the antagonists. The worst offender in it is Alexia though. Even the other demons thinks she's excessively evil about it. Sailor Dark Mercury has a similar stance towards recruitment.
- In the Pony POV Series, Discord did this in Dark World to the Mane Six and the Doctor, turning them into the Chaos Six and the Valeyard.
- TRON Legacy: There's a reason Rinzler never takes off the mask, speaks in a distorted stutter, and... stops fighting Sam once he realizes that Sam is a User. He's a corrupted Tron.
- Star Wars: Emperor Palpatine's conversion of Anakin Skywalker into the infamous masked cyborg counts, although Annie had already joined the Dark Side and was significantly weaker afterwards.
- An interesting case in Despicable Me 2, where Gru's Adorable Evil Minions are kidnapped and turned into truly Evil Minions by injecting them with Psycho Serum.
- The entire crew of the Cygnus in The Black Hole.
- As seen in the Comics folder above, this is what happens to Bucky Barnes in Captain America: The Winter Soldier.
- In Troll Torok transforms the various tenants of the apartment complex into creatures to do his bidding, only Jeanette retains her original appearance after her transformation.
- The Taken in The Black Company are powerful wizards, defeated in battle and remade into powerful servants. The transformation seems to involve death and the victim remains human in shape only at best.
- Zaknafein in the second book of The Dark Elf Trilogy is reanimated this way by a drow ritual known as zin-carla.
- In The Lord of the Rings, this was the purpose of all the lesser rings (with the One made to control the resulting minions) but only the human recipients of the Nine were fully corrupted and became the Nazgûl. The Nazgûl themselves also have this ability-being stabbed by one of their Morgul Blades turns the victim into a wraith. It nearly happened to Frodo, if it hadn't been for Glorfindel's (Arwen's in the movie) timely rescue.
- In A Song of Ice and Fire, the Others raise the dead as wights. It's heavily implied that Qyburn did this to the late Gregor Clegane, turning him into Ser Robert Strong.
- Mistborn: The Original Trilogy does this interestingly. Marsh, older brother of Kelsier, infiltrated the Steel Ministry disguised as an acolyte. He attracted the attention of the Steel Inquisitors, who, owing to how good Marsh's impersonation was had Marsh forcibly converted into an Inquisitor himself, a stomach-churning procedure Marsh certainly did not sign up for. However, the Inquisitors were not aware that Marsh was a spy, and he was able to retain his personality despite the mind-altering affects of the transformation and betrayed the Inquisitors at a crucial moment, killing their leader Kar and several other high-ups and leading directly to the overthrow of their boss, the Lord Ruler. Unfortunately, the dark god Ruin—ultimate source of the magic that powered the Inquisitors and whom the Lord Ruler had been holding at bay—now gained greater power to affect the world, so he possessed Marsh and made him into The Dragon. So poor Marsh ended up a minion after all, even if it didn't quite work out the way that those who reforged him wanted it to.
- Star Wars Legends:
- Some Yuuzhan Vong Shapers tried to do this to Tahiri in the New Jedi Order series (though their primary goal was brainwashing her into believing she was Yuuzhan Vong herself, they also intended to make physical modifications to bring her closer to a Vong physical appearance). Unfortunately for them, Tahiri was rescued and the head Shaper was killed before the process was complete. Unfortunately for Tahiri, there were lingering effects.
- After Darth Vader's physical Emergency Transformation is complete, Dark Lord—The Rise of Darth Vader focuses on Darth Sidious's attempt to restore Vader's confidence in himself and fully indoctrinate him into the Dark Side.
- This is how Chytrine got her Quirky Miniboss Squad, the sullanciri, in The Dragon Crown War. A group of heroes were sent to kill her, and she captured them, manipulated them into accepting a Deal with the Devil with her, and then used immensely powerful magic to convert them into Nigh Invulnerable undead warriors. The specifics of the transformation varies from sullanciri to sullanciri (it's implied to be at least in part Personality Powers), ranging from Anarus (Wolf Man), to Ganagrei and Tythsai (visibly decaying undead), to Neskartu (wraith-like sorcerer) to Myrall'mara (glowing and ethereal) to Nefrai-kesh, Nefrai-laysh, and Quiarsca (outwardly normal, but with Glowing Eyes of Doom and a bit of Uncanny Valley about them), but all were physically transformed in some manner, and had their personalities overwritten with ones more in line with what Chytrine wanted in lieutenants; the procedure is apparently unspeakably agonizing.
- In Counselors and Kings, Big Bad Akhlaur is a necromancer who possesses a spell that can forcibly convert another wizard into a lich - and place them totally under his control (much to the horror of his Bastard Understudy, Kiva, who didn't think such a thing was possible and realizes she may have bitten off more than she can chew with her attempts to manipulate him). The only victim of the spell on-page is Akhlaur's former friend Vishna.
Live Action TV
- In the second season of Dark Angel the formerly dead Zack returns as a cyborg. Sort of like Robocop, only less well-intentioned.
- In Power Rangers Mystic Force and Mahou Sentai Magiranger, Leanbow/Isamu was The Hero of the Great Offscreen War twenty years prior, who stayed behind to make sure that the seal on the evil can worked. This naturally resulted in him being trapped in there with the evil badly wounded from fighting off an army alone, which then took his unconscious body and reforged him into Koragg/Wolzard, their new Black Knight dragon. Yes, becoming a Black Knight qualifies as being reforged, it's a transformation rather than a suit of armor, and he stayed in that form the full twenty years until the spell was broken.
- In Kaizoku Sentai Gokaiger, Joe learns that Walz Gil's bodyguard Barizorg is actually his old friend Sid, whom he thought had sacrificed himself to help him escape, but was actually rebuilt into a cyborg and brainwashed.
- Several of the heroes in the early series of the Kamen Rider franchise come out of failed attempts to do this, starting with the original one. Of course, there are also villains who are the result of successful attempts.
- JackMoon from Madan Senki Ryukendo is a Noble Demon who is set up as The Rival to Kenji Narukami, the eponymous Ryukendo. He dies in what he sees a honorable death against Kenji...only to be rebuilt into the mindless cyborg Mekanimoon by the Evil Genius Baron Bloody. He does return to his old self after the Big Bad is destroyed and dies for real in a Post-Climax Confrontation against his rival Kenji.
- In Smallville, the Monster of the Week in the episode "Prototype" turns out be Wes Keenan who Lois grew up with as a Military Brat, turned into a genetically engineered Super Soldier for Lex Luthor. He was drafted into Afghanistan, severely injured in a battle, and LuthorCorp retrieved his body. He was officially declared KIA, though he unknowingly made a Deal with the Devil, with Luthor promising that he will properly serve his country like never before. Luthor had scientists experiment on him with DNA from several "meteor freaks" and a "Zoner" (aliens from Krypton/had contact with Kryptonians), giving him Super Strength (enough to rival Clark), barrier projection, Invisibility and Super Speed. More so, he was conditioned so that he remembers nothing of his old life, making him a perfect assassin for pesky senators attempting to shut down Luthor...
- Temporarily happened to Captain Picard in the Star Trek: The Next Generation episode "The Best of Both Worlds", as he is captured and assimilated by the Borg to serve as their mouthpiece Locutus.
- In Lexx, His Divine Shadow stabbed Kai, last of the Brunnen-G, after the latter's doomed attempt to defeat him. Believing that Kai deserved a punishment beyond death, the Divine Shadow had Kai's body "decarbonized" making him into a brainwashed undead Divine Assassin. Two thousand years later, this bit the Divine Shadow in the ass when Kai managed to regain his memories and his willpower.
- Agents of S.H.I.E.L.D.: Mike Peterson is seemingly killed in an explosion by Centipede in "The Bridge". However, the end of the following episode reveals that he survived, albeit captured, heavily scarred and minus a leg, as well as freshly implanted with a Centipede eye device. This is built upon two episodes later, as he's given a cybernetic leg in order to move about as The Clairvoyant's new chief enforcer, Deathlok.
- In The Protomen's Rock Opera, after being destroyed by Dr. Wily's robots, Protoman is rebuilt by Wily and returns as the general of Wily's forces, filled with a seething hatred for the humans who simply let him die on their behalf rather than making any attempt to stand up for themselves. Protoman is an interesting case, in that he appears to have joined Wily willingly, without any coercion involved. He's just that bitter.
- Magic: The Gathering:
- In Judgment, Kamahl's friend and mentor Balthor is brought back from the dead as a superpowered zombie minion after Cabal necromancers find his body post-Heroic Sacrifice.
- In the Onslaught Cycle, Kamahl's sister gets hit even harder — she gets transformed into Phage the Untouchable, a veritable avatar of death.
- Death knights in World of Warcraft are a borderline example - they are Elite Mooks but the people to be transformed are hand-picked to ensure quality.
- They were this exactly in War Craft II: slain Azerothian Paladins reanimated into Undead Squishy Wizards for the then-evil Horde. Warcraft III's Liches are those same Death Knights retransformed into frost magic users (though they kept the Death and Decay spell), and the new generation of Death Knights are human nobles reanimated as melee heroes with a much better survival rate.
- Arthas' transformation from Paladin to Death Knight isn't shown, but it definitely involves this.
- MOTHER 3: Porky uses the body of Claus, your brother who goes missing at the end of Chapter 1, for creating his cyborg henchman.
- Sarah Kerrigan is corrupted to serve the Zerg Overmind in the original StarCraft (and that she eventually emerges on top).
- Seiken Densetsu 3 eventually reveals that this happened in the Darkshine Knight's backstory (assuming you picked Duran as your main character, anyways) - namely, the Dragon Emperor used his magic to revive the knight Loki (no, not that one) after the two of them dropped into a bottomless pit during a struggle, and neither was ever found.
- While it's technically more of an Unwitting Pawn, in Overlord the Player Character is really one of the heroes who defeated the previous Overlord after being recovered after a No One Could Survive That!.
- Mu-12's origin in BlazBlue. More specifically, she's Noel Vermillion note . Terumi/Hazama mind raped her into nihilism, finished the process of turning her into a cyborg killing machine and sicked her on Ragna. All just as a brief distraction so he could kill a god. This far from the only time Relius and Hazama invoke this trope, either;
- The ending of the second game also implies that Hazama and Relious Clover did this to Ragna and Jin's apparently dead little sister Saya to use as some sort of pupper ruler/vessel for a higher power.
- The Extended edition also all but says that Hazama's minion "Phantom" is Konoe A. Mercury AKA Nine, one of the six heroes.
- In "Phase 1" the protagonist Kazuma Kval merges with Terumi (essentially just being a physical body for him) to create Hazama.
- In Chrono Phantasma, Izanami the Goddess of Death using Saya as a vessel does this to Ragna, making him her slave.
- Bulletstorm: Ishi's fate, if you stayed after the credits. Although the screen remains black, the dialogue is implies that the Big Bad not only survived, but managed to patch up Ishi after his heroic sacrifice, and cranked his soulless AI to 11.
- Subverted in Quake IV. Halfway through the game, protagonist Matthew Kane is captured by the Stroggs and turned into one of them. However, Kane's fellow EDF soldiers come and rescue him before the Stroggs can indoctrinate him.
- Jade Empire: Not only is Death's Hand not the Big Bad, or even close to it, it turns out that he's the spirit of the Emperor and Sun Li's youngest brother, mortally wounded at Dirge and magically bound to Sun Li's armor.
- The Dark Side ending to Star Wars: The Force Unleashed has the mortally wounded Starkiller turned into something even worse than Vader and sent out as an assassin, with Palpatine making it clear that as soon as he has outlived his usefulness, then he will die…but not before.
- In Xenoblade, all of the Faces are examples of this trope, most notably Mumkhar, Fiora, and Gadolt. They're cybernetically altered Homs who pilot giant robots, rather than autonomous Mechon. This renders them immune to the Monado, but susceptible to any and all Brainwashed and Crazy-related tropes.
- Mass Effect:
- Rare heroic example: happens to Shepard at the beginning of Mass Effect 2. Notably, the Illusive Man didn't bother installing any real Restraining Bolts, trusting instead in Shepard's gratitude and their mutual goals to ensure that he/she would work for him post-resurrection. Whether he's right depends on the player's choices, although he's ultimately proven wrong in the third game. Shepard can also be made to pay lip service to the idea that Cerberus is working for him/her instead of the other way around.
- If Shepard fails to rescue her in time in Mass Effect 3, this will happen to Jack. It also potentially happens to Legion, but only if you sent their platform to Cerberus without ever getting to know them in the first place. Morinth will also show up as a banshee if she was alive at the end of Mass Effect 2.
- This happens to Nabooru, courtesy of Koume and Kotake, in The Legend of Zelda: Ocarina of Time. She is forced to act as an enhanced Iron Knuckle.
- In Soul Nomad & the World Eaters, Gig used to be the benevolent Master of Death of Haephnes Vigilance. He was slain by Median and had his soul reforged by Drazil into its current Omnicidal Maniac form. Ironically, the protagonist, even on the heroic path, is perfectly capable of beating up and press-ganging people in the street should they want to; and three secret characters can be challenged, defeated, and dominated into your army, despite their protests.
- In Dungeon Keeper, any prisoner who dies in your dungeon will be raised as a loyal skeleton soldier.
- In The Lord of the Rings Online, those who are stabbed by the Morgul Blades of the Nazgul eventually become the red-robed Cargul, lesser wraiths under the control of the Nine, as happens to the Ranger Amdir. Ivar the Blood-hand, one of the Gaunt-lords, is particularly fond of doing this, and does this with an evil Dwarf-lord named Skorgrim Dourhand in the finale of the Elf and Dwarf introductory quests.
- Shin Megami Tensei games have this. As a general rule, once you've slain a boss or midboss, regardless of its previous allegiance or alignment, you can summon it as a new minion at the right level. As an example, in Nocturne, you can slay Metatron, the Voice of God... and force it into your service against God's representative in the Vortex World. Another good example is Futomimi, the Manikins' seer. Instead of reviving him as a Manikin, he returns as a demon. As an added bonus, with careful tinkering, you can slap any moves you want on them.
- In Neverwinter Nights 2 after Black Garius' death, he and the priests who were helping him are resurrected by The King of Shadows as Shadow Reavers, immensely powerful undead beings who act as The King's main agents for the rest of the game.
- Fire Emblem Awakening and Fire Emblem Jugdral both contain the Dreadlords, 12 immortal warrior souls who posses the bodies of powerful fallen warriors. Fire Emblem Jugdral will use allies who you either failed to protect or were not recruited, while Fire Emblem Awakening implies the Bad Future versions possessed the allies who were killed by the Big Bad.
- In WildStar, the Eldan security systems of Nexus are fond of using Augmentation to turn would-be hostiles to their side.
- In The Adventures of Lomax, this is what Evil Ed does to all the lemmings except Lomax, turning them into all sorts of monsters.
- Peashy of Hyperdimension Neptunia Victory was kidnapped and forced into amnesia by one of the villains after she ate a certain apotheosis-inducing item from another one of the villains, becoming a CPU as a result. Neptune and Plutia invoke an "I Know You're in There Somewhere" Fight using various items to trigger her dormant memories, (though they had to weaken her first).
- In Evil Genius, this is how you make Freaks: dipping a body bag into your Bio-Tanks induces a terrifying resurrection, and the result is peak Dumb Muscle — a Freak's maximum Attention is still too low to avoid your own traps. This is also how you permanently dispose of Dirk "Totally Not Rambo" Masters. Turns out he's hopped up on tons of illegal steroids, and the chemicals in your Bio-Tanks cause a delightful Dangerous Phlebotinum Interaction.
- In Marvel vs. Capcom: Clash of the Superheroes, we get Shadow Lady, a a non-canon variation of Chun-Li, forcibly turned into a cyborg by Shadaloo. Aside from retaining a few moves from her non-cyborgified variant, Shadow Lady shoots homing/heat-seeking missiles from her back, thrusts forward with a drill, encase herself in a electric barrier (that also deflects attacks and stuns opponents) and fire a large beam (Big Bang Laser) from her palms.
- Amélie Lacroix from Overwatch was the civilian wife of Overwatch agent Gérard Lacroix, who foiled the terrorist organization Talon's plans at every turn. So she was kidnapped, tortured, brainwashed, and experimented on for the sake of killing him. When the task was completed, they turned her into a living weapon, complete with a new name: Widowmaker.
- In Dominic Deegan, when Karnak takes over in hell, he transforms the damned knight Sigfried to serve him as The Dragon. This bites him in the ass when his new servant regains his free will through a freak magical accident and goes on to overthrow him.
- In The Order of the Stick:
- Subverted when Tsukiko rants about turning Miko Miyazaki into a Death Knight, but quickly changes her mind on seeing the condition of the corpse. This is partly a Take That! at fan speculation that something like this would happen.
- Played straight when Malack kills Durkon and raises him as an enslaved vampire, who is kept in thrall until Malack's death. Though Malack mentions freeing him when circumstances are better, this only gives mental autonomy to the evil spirit possessing Durkon's soul and corpse, but leaves Durkon's spirit trapped.
- Xaos's sword in The Wotch does this instead of killing what it stabs.
- Evan, Ethan's McAwesome's counterpart in Shortpacked!, was killed by a bomb planted by Sydney Yus and thrown out of the store by Ultra-Car, then brought back as a cyborg by Sydney to get revenge on U.C. (It makes as much sense as anything Sydney does.)
- F.O.W.L. tried to do this to Taurus Bulba on Darkwing Duck.
- In Aladdin: The Series, Mozenrath turned the evil wizard who trained him into one of his Mamluk minions.
- Galvatron in The Transformers is a literal example. Interestingly, the reforging completely failed to make him loyal, or even more evil; all it did was change his appearance and abilities, and make him significantly more Ax-Crazy. The Big Bad had to resort to repeated psychic torture to get anything resembling obedience.
- Two scientists who hate all Transformers due to an attack from the Decepticons leaving one's daughter crippled attempt to do this when they recover the body of Optimus Prime, by keeping him powered by some experimental spores containing a Hate Plague that would leave him insane and murderous. When their attempt to repair him fails, they decide to do the next best thing and lure the Autobots to their lab to recover his body, so they can expose them to the spores directly.
- In Batman Beyond: Return of the Joker, The Joker turns out to have done this to Tim Drake, in a way that marks his definitive crossing of the Moral Event Horizon in the DC Animated Universe. After capturing him while he was on patrol, Joker proceeded to horribly torture and brainwash the poor kid over an extended period, eventually turning him into "Joker Junior." The brainwashing held out until Batman and Joker's final battle when Joker ordered Tim to finish Batman off, only for Tim to kill Joker instead.
- In the sequel series to Beast Wars, Beast Machines, Megatron has turned tons of garden-variety transformers into mindless mooks, and two out of the three members of his Quirky Miniboss Squad are ex-heroes who have been reforged into new bodies/personalities.
- Graft in Phantom 2040, rebuilt as a Cyborg by the series' Corrupt Corporate Executive Big Bad.
- In Phineas and Ferb The Movie: Across the 2nd Dimension, in the other dimension Perry the Platypus is captured and turned into Perry the Platyborg, general of Doofenshmirtz's army.
- The Psychocrypt in Adventures of the Galaxy Rangers. The victim has his Life Energy removed, placed in a Soul Jar, and the "jar" used to power a high-level Mook through which Her Travesty has a Psychic Link. Anything the poor bastard might have known is free for her to rummage through and use as a weapon, while they're conscious and unable to do anything about it.
- In Sonic SatAM, the robotized Mobians are this.
- Sterling's rival Barry in Archer, rebuilt as a cyborg by Soviet (er... Russian?) Superscience. Subverted in that he betrays his superior, and usurps the position as head of the KGB (only to be replaced himself in his absence).
- TRON: Uprising: Repurposing takes programs and changes their directive, not necessarily their personality, and makes them loyal to Clu. The victims get their Tron Lines changed to Red, and their ailments removed. It was done to Tron's security team, among thousands of other programs, as well as Cutler. It was almost done to Tron, and may have been done to Dyson, though by all accounts he probably volunteered.
- For season three of Jackie Chan Adventures after Uncle imprisons his original dark chi warriors Daolon Wong turns Chow,Finn, and Ratso into his new dark chi warriors to replace them, he later does the same to Hak Foo, they remain this way until Uncle finally defeats Wong in a chi battle.