->"''I will rebuild what the many have lost. I will create a future with limitless possibilities.\\
I will protect and sustain. I will act as guardian for the many.\\
And throughout it all, I will never forget.\\
I will remember the ones who sacrificed themselves so that the many could survive.\\
And I will watch over the ones who live on. Those who carry the memory of the man/woman I once was.\\
The man/woman who gave up his/her life to become the one who could save the many.''"
-->-- '''Commander Shepard''', ''VideoGame/MassEffect3'' [[note]][[https://youtu.be/lX7HDcvw2pk?t=792 Paragon, Control Ending]][[/note]]

This character has been hit with a ViralTransformation, EmergencyTransformation, become a {{cyborg}}, demon, magical creature, [[AlienTropes alien]] or [[TomatoInTheMirror discovers they were never human at all]]. Despite this, and regardless of any angst over WhatHaveIBecome, they decide that rather than go down the path of TranshumanTreachery and be a SmugSuper, BlackShirt, or TheQuisling, they will do everything in their power to stay a part of humanity. And if their new species/transhuman fellows [[AntiHumanAlliance are anti-human]], they will vow to protect humanity in a pseudo FaustianRebellion.

This can also include {{transhuman}}s who cast themselves in a shepherd-like role for mankind. This doesn't include forcibly applying WhatMeasureIsANonSuper to bootstrap humanity up, though. That's more of a VisionaryVillain who believes UtopiaJustifiesTheMeans. Many {{Friendly Neighborhood Vampire}}s fall in this category.

If the transformation is due to TheVirus, this requires copious HeroicWillpower. These characters can usually pull off a SheepInWolfsClothing gambit. See also MonsterAdventurers. Related to MySpeciesDothProtestTooMuch, which refers to creatures that aren't former humans.

{{Opposite Trope|s}} to SuperSupremacist, a superpowered individual who regards the non-superpowered as beneath them. SuperTrope to VampireRefugee and PhlebotinumRebel. Contrast TranshumanTreachery. See also/compare AGodIAmNot.

%%If you have time, please take time to put examples in alphabetical order. This page Administrivia/HowToAlphabetizeThings should help you with that.


[[folder:Anime and Manga]]
* In ''Manga/AttackOnTitan'', [[spoiler:Eren is a human who can transform into a Titan.]] He is firmly on the side of humanity [[spoiler:unlike the other Titan Shifters, who are either TheMole, or, in case of Ymir, a HeelFaceRevolvingDoor.]]
* In ''Manga/{{Claymore}}'', the eponymous warriors are [[HalfHumanHybrid Half human half demons]] who choose to fight for humanity's sake. [[spoiler: Just about every one who finds out that the organization which transformed them does ''not'' have the best interests of the citizenry at heart ends up going rogue.]]
* In ''Manga/SilentMobius'', some [[spoiler: Type 4]] Lucifer Hawks ([[spoiler: Rally and Katsumi!]]) raised as humans decide to serve humanity.
* The protagonist in ''Anime/BlueGender'' has a "disease" called B Cells which are a form of GaiasVengeance. It's intended to cause humans to rebel against their peers and go kill crazy (which it does spectacularly to two other characters). He manages to stay sane despite the various hardships Gaia and humanity throw at him.
* Ayato in ''Anime/RahXephon'' is part Mullian (basically a human subspecies with blue blood) and when his Mullian blood manifests, there's concern he'll pull a FaceHeelTurn and join the Mullians, but he remains a nice guy on the side of his friends.
* [[McNinja Schwartz Bruder]] in ''Anime/MobileFighterGGundam'' is this. [[spoiler:He is a dead body occupied by the DG (Devil Gundam) Cells to live. Despite being made up by the cells of the BigBad, he is the Devil Gundam host Kyoji Kasshu's physical manifestation, driven to save his brother and stop the Devil Gundam]].
* In ''Manga/{{Hellsing}}'':
** While most vampires revel in their non-humanity even if they fight for humans, Seras does everything in her power to remain as human as possible without neglecting her duties to the organization... which involve drinking blood so that she can use her vampiric powers to kill vampires that threaten humanity.
** Alucard's a weird case. He'll gleefully slaughter ordinary humans just for being ordered to attack him, but he also believes that monsters like himself are, in truth, weak because they could not bear to live mortal lives. He believes firmly that humans are the only ones who could ever truly defeat him, the way Abraham Van Helsing and his companions did in the past. Thus he has a loathing for humans who choose to become monsters for the sake of power, especially the power to defeat him.
* In ''Anime/{{Nightwalker}}'', Shido, a vampire, defends humans from the nightbreed. He apparently has been a vampire for a long time and at first he was not so friendly to humans, but later changed his mind.
* In ''LightNovel/TrinityBlood'', Abel Nightroad is a Cruznik, a being that feeds upon vampires (and is thus two steps above humans in the [[FoodChainOfEvil food chain]]). That doesn't stop him from devoting his life to defending humanity, and using his relatively harmless default form to masquerade as a normal human. He is an interesting example of a Pro-Human Transhuman in that he was a DesignerBaby and thus born a transhuman. [[spoiler: He was also originally quite anti-human.]]
* Kira in ''Anime/MobileSuitGundamSEED'' is accidentally this, being a Coordinator fighting for an army consisting entirely of Naturals (in a war started to exterminate his kind!). Not really his intention: he only fights to protect his friends. When it's revealed that both sides have genocidal intentions, he and his girlfriend, Lacus, form the Three Ships' Alliance, which includes deserters from both the Natural and Coordinator armies, and want an end to the war. Naturally enough, several other Pro-Human Transhumans, including Lacus, Athrun, Dearka, and the Desert Tiger, end up in this faction.
* Amuro Rey of ''Anime/MobileSuitGundam'' upon discovery and confirmation that he is in fact a Newtype argues that this does not make him special or any better than anyone else on the White Base crew. Even later on in ''Anime/MobileSuitGundamCharsCounterattack'' he outright says he is not going to force humanity to change and has faith that humanity can improve on its own.
* This is {{invoked|Trope}} in ''Anime/TigerAndBunny'' as all of the [[{{Superhero}} Heroes]] are trans-humans called [=NEXTs=] with extraordinary powers which they use to save people and stop crimes, all of which are recorded by Hero TV for people's entertainment.
* Most of the characters in ''Manga/{{GUNNM}}'' [[MarketBasedTitle /]] ''Manga/BattleAngelAlita'', largely justified by the fact that, because the percentage of {{Hollywood Cyborg}}s in the setting is roughly equal to the percentage of the Americans owning cars, the question of WhatMeasureIsANonHuman simply doesn't come up. It is still played straight in cases of [[FriendlyNeighborhoodVampire Caerula Sanguis]] and [[PersonOfMassDestruction the protagonist]], though. In fact, even [[BigBad Aga]] [[VillainWithGoodPublicity Mbadi]] is in it just for the [[PresidentEvil world]] [[EvilOverlord domination]].
* The sequel to ''Manga/TokyoGhoul'' has the members of the Quinx Squad, all experimental {{Half Human Hybrid}}s created as a new potential weapon for CCG to use against Ghouls. Their existence and usage is controversial, with many other investigators expressing unease about the organization performing human experimentation and blurring the line between humans and Ghouls. In particular, team leader Haise Sasaki was transformed into a Half-Ghoul against his will and made the decision to use his new-found powers to protect humanity. [[spoiler: Or rather, after Ken Kaneki was fatally wounded and lost his memory, CCG took him in and studied him before putting him to work as a potential trump card. As such, it isn't clear how genuinely "pro-human" he is]].

[[folder:Comic Books]]
* Just about every superhero ever, or at least the ones that aren't space aliens or [[BadassNormal Badass Normals]].
* ComicBook/{{Blade}} chooses to use his vampiric abilities as a {{Dhampyr}} and daywalker to hunt vampires.
* In the original ''ComicBook/ThirtyDaysOfNight'', sheriff Eben purposefully infects himself with vampirism and manages to save the survivors with his newfound strength. [[spoiler:He then kills himself since he can feel the bloodlust coming on and knows he can't maintain his original self for much longer.]]
** The second comic series, ''Dark Days'', has an originally less-than-nice vamp pulling a gradual HeelFaceTurn (at first helping Stella out purely for revenge against the BigBad, but later on out of genuine feelings for her); by the end of the story, he doesn't even try to feed on her, despite having the perfect opportunity, which is saying something as vampires in that 'verse are pretty much all bloodthirsty (in both senses) AlwaysChaoticEvil sociopaths from the moment they're turned, even if they were dedicated vampire killers just before. [[spoiler: Unfortunately, after his resurrection, vampire!Eben is not quite so inclined...]]
* ComicBook/{{Hellboy}} is a half demon fighting demons for humanity.
* The ''ComicBook/XMen'' are a whole organization of mutants who behave this way.
* Creator/DCComics hero ComicBook/{{Metamorpho}}.
* Michael Costner and Sasha Bordeax, two of the ''ComicBook/{{OMAC}}s'' in the post ComicBook/InfiniteCrisis continuity.
** Sasha Bordeaux, formerly a Batman companion and then part of Checkmate, was infected with [[TheVirus the O.M.A.C. nanovirus]] to become a more advanced O.M.A.C., with enough free will to coordinate and command the other units. That enables Sasha to rebel, [[spoiler: destroy Brother Eye]] and later reclaim a less advanced, but more useful and human-like cyborg form for herself.
** Michael Costner, a young thief and grifter is activated as a regular powered O.M.A.C. unit to help rebuilding a thrashed Brother Eye. A peculiar combination of [[TheAtoner guilt for his past as a common burglar]], lack of self worth, his earlier bout with drug addiction and ThePowerOfLove enable Michael to shake off his programming and fight against Brother Eye for the sake of the world and his girl. [[spoiler: In the end, while his pregnant girlfriend Vienna acquires his very same powers and rushes to his help, she dies and with Brother Eye deactivated, Michael loses access to his powers. In a bittersweet ending, Clark Kent manages to have Michael and Vienna revered as heroes and saviors of the human race]].
* The Thing of ''ComicBook/FantasticFour''. His teammates too, although they can pass for ordinary people in a way he can't.
* Dr. Manhattan in the beginning of ''Comicbook/{{Watchmen}}''. Though this is actually his main character arc-- he becomes less and less so as the story goes on, eventually getting to "Why would I save a world I no longer have any stake in?". By the end, [[spoiler: Silk Spectre II must convince Dr. Manhattan that humans lives are worth protecting. It's the revelation that her father is [[SociopathicHero The Comedian]] that does it - realizing the sheer improbability of human life is enough to restore his interest in protecting it.]]
* Gunn in ''Angel: After The Fall'' (a direct sequel to the ''Series/{{Angel}}'' series). He is determined not to become a monster and continue being a hero, though he's really trying to prove he's better than Angel, who he blames for letting him get turned.
* The Confessor in ''ComicBook/AstroCity'' is a Batman-like hero who is secretly [[spoiler: a vampire. He wears a cross as his ChestInsignia so the constant pain will help distract him from his thirst. After he's destroyed, his sidekick is surprised to find the Cross Breed, a local Christian super hero team, mourning him; they assert that as far as they're concerned, he was always doing the Lord's work.]]

* Shinichi of {{FanFic/Experiment}} is turned into a {{cyborg}} by Ai, but because he's the only one around, he has to do the {{masquerade}} and try to be as human as possible.
* The shinigami of Creator/{{Vathara}}'s ''Fanfic/ProjectTatterdemalion'' are {{Super Soldier}}s made this way through a live virus vaccine against a superbug, giving them CombatTentacles, [[PoisonousPerson venom]], AbsurdlySharpClaws, an {{EMP}}-based StarfishLanguage, SuperStrength, FlashStep, [[MindOverMatter destructive psychokinesis]], a [[HatesBeingAlone loneliness]] that can only be alleviated by staying near the [[TrueCompanions pack]], a HealingFactor that works fast and a bad case of CuddleBug. Because TheRepublic [[NoTransHumanismAllowed does not allow]] BioAugmentation, they are {{UnPerson}}ed.
* Adam Jensen in [[Fanfic/MassEffectHumanRevolution [=Mass Effect: Human Revolution=]]] is this trope even more than he was in [[VideoGame/DeusExHumanRevolution [=Deus Ex: Human Revolution=]]], to the point where Hein means to use him to force humanity as a whole into a HeelFaceTurn
** "I'm going to turn Jensen into the most powerful human being in the Galaxy. I'm going to make the rest of mankind turn green with envy and stew in their jealousy as Jensen comes to their rescue, again and again and again, and go mad when he fails to turn into the monster they all expect him to become. "


* David Bowman in ''Literature/TwoThousandTenTheYearWeMakeContact''. Transformed into a demigod by the Monolith, one of his first acts after awakening in his new form is to say goodbye to his wife and mother, as well as sending a warning to the crew of the ''Discovery'' for them to evacuate the area around Jupiter immediately before the Monoliths turn it into a star.
* Juxtaposed with TranshumanTreachery in ''Film/CaptainAmericaTheFirstAvenger'': [[ComicBook/RedSkull Johann Schmitt]] believes that Erskine's SuperSerum has elevated him above humanity, while [[ComicBook/CaptainAmerica Steve Rogers]] takes Erskine's understanding of the serum to heart - as it [[PersonalityPowers enhances everything a person is]], Rogers states that the Serum simply made a monster such as Schmitt more monstrous, while ''he'' sees his enhancement solely as a greater responsibility towards his fellow man.
* ''Film/{{Lucy}}'': Protagonist Lucy is exposed to a SuperSerum which vastly expands her mental powers, but which will surely kill her. She searches for a way to record her new-found knowledge for the common good before she dies. Features more shooting and shouting than you might think from that summary.
* Defied in ''Film/{{Ultraviolet}}'', where a human tries to reason with the [[OurVampiresAreDifferent not-vampire]] heroine, saying she was human once, too. She dismisses it, saying that humans were who made her that way and then wanted her dead, so she owes them no loyalty.
* [[OurVampiresAreDifferent The Brotherhood]] is presented this way in ''Film/PerfectCreature''. They are an [[OneGenderRace all-male]] order of [[FriendlyNeighborhoodVampire vampire monks]] that are perceived as superior to humans in every way (stronger, faster, smarter and long-lived) therefore closer to God, but are nominally sworn to guide and protect them and have managed to live in peace and prosperity with humans for centuries, surviving on willingly donated blood by church goers, and they consider abhorrent to drink directly from the body. [[spoiler: However, its revealed that they are corrupt in many ways, such as subtly keeping mankind dependent on their rule by outlawing scientific research, and being indirectly responsible for the main villain's actions by practicing it in secret: in a effort to produce more vampires after no new ones being born in decades, they commission the BigBad to perform experiments on the virus that ends up infecting him and driving him insane]].


* Terry Pratchett's ''Literature/{{Discworld}}'':
** In ''Discworld/ThiefOfTime'', the character Myria [=LeJean=] is an Auditor, an enemy of humanity, but upon taking human form she realises what it is she seeks to destroy and becomes opposed to her own people, in defence of humanity.
** In ''Discworld/{{Snuff}}'', the Dwarvish demonic entity The Summoning Dark, vanquished by Sam Vimes, becomes his ally in the cause of law and order.
** Also, DEATH himself is fond of people, and on more than one occasion actively defends them. His granddaughter, Susan Sto Helit, is a straighter example since she actually IS human, but inherited some of her grandfather's traits and abilities. She's also his most reliable ally in protecting the people of the Disc from the Auditors of Reality.
* In Creator/FredSaberhagen's ''Literature/{{Berserker}}'' stories, Hilary Gage, an artificial intelligence designed to mimic every aspect of the human thought process, continues to think of "himself" as human, at least with respect to interstellar politics, despite being very much aware of the fact that "he" has no biological body parts. Later, he [[spoiler:downloads himself into a berserker warship's central AI, and has to make sure he maintains enough control to prevent the warship from continuing its fight against humanity.]]
* In ''Literature/OldMansWar'', the CDF consists almost entirely of elderly men and women [[BrainUploading downloaded]] into genetically enhanced pseudo-clones ([[{{Tykebomb}} the rest]] is even less human). During boot camp one guy asks why they're bothering to defend baseline humanity when their new bodies are [[EvolutionaryLevels the next step in human evolution]]. [[DrillSergeantNasty Sergeant Ruiz]] tells him he couldn't be more wrong, all the alien DNA in their genomes makes them sterile and thus an evolutionary "dead end". In fact one of the reasons for the advanced enlistment age is so most of the recruits would have grandkids back home they would want to protect from baby-eating aliens.
* In [[http://www.karenetaylor.com/ Karen E. Taylor's]] ''[[http://www.goodreads.com/series/65538-the-vampire-legacy Vampire Legacy]]'' series, VampireDetective Dierdre prefers working with humans to other vampires, despite the FantasticRacism that carries.
* In Creator/LarryNiven's ''Literature/KnownSpace'' Pak Protectors evolved to be this, they are hardwired to protect their descendants no matter what, however they will attempt to exterminate any other sapients including other Paks (except for the rare few whose descendants are all dead and have dealt with it by protecting the whole species), and will even kill their descendants who have mutations. Humans evolved from a LostColony of Pak Breeders and have differentiated so far that Pak Protectors will destroy them if given the chance, however humans can become Protectors and are intelligent enough to rationalize that they should protect all of humanity. Unfortunately [[TheUnfettered this includes using the virus]] that causes Protector transformation on an entire planet to [[WhatTheHellHero kill off everyone too young or too old to become a Protector]] and create an army of childless Protectors [[IDidWhatIHadToDo to fight off the coming Pak invasion fleet]].
* In the ''Literature/RevelationSpaceSeries'', the Conjoiners are a faction of Transhumans who use advanced nanotech to enhance their minds and physiology. When they learn of [[spoiler: the Inhibitors coming to destroy humanity]] they make preparations to flee, leaving the "baseline" humans to their fate. However, their nominal leader, Clavain, [[spoiler: defects in an attempt to warn human space of what's coming.]] Captain John Armstrong Brannigan also became a pro-human transhuman after he [[spoiler: becomes one with his starship]] and got over his [[DrivenToSuicide repeated attempts to kill himself]], cooperating with Ilia Volyova to try and save as many people from Resurgam as possible before [[spoiler: the Inhibitors blast it with a directed solar flare]].
* The Great Ones in ''Literature/BelisariusSeries'' embody this trope, being all for freedom, diversity and free adaptation of the human race to the new circumstances, while [[TheRival their archrivals]] the New Gods are {{Politically Incorrect Villain}}s bent on [[ANaziByAnyOtherName racial purity]] and conformism.
* This is the case in stories written by Creator/GregEgan, thereby [[JustifiedTrope justifying]] how transhumanism led to utopia rather than some sort of crapsack FeudalFuture-- apparently the process causes those who undergo it to become more empathetic than baseline humans, meaning that the first transhumans worked selflessly to peacefully uplift everyone else to their level instead of exploiting or subjugating them.
** The trope is downplayed in ''Literature/{{Diaspora}}'' in the treatment of the ''statics'', people who remain baseline humans rather than accept any BioAugmentation, [[{{Cyborg}} cybernetics]], or BrainUploading. Their choice is respected and their communities protected, but most individuals disregard them as being backwards, short-lived, and absurdly limited in their capacity for experience. [[spoiler:When the Earth is scoured by a gamma ray burst, a few [=AIs=] try to save them by [[EmergencyTransformation forcibly uploading]] as many as possible, others offer assistance on the statics' terms, and many have no qualms about standing back to watch the organics' self-righteous principles come back to bite them in the rear.]]
* Mira of ''Literature/TheAccidentalSuperheroine'', chooses to side with humanity rather than Orlov, although she has the occasional second thought about it when government organizations attempt to capture her for experimentation.

[[folder:Live Action TV]]
* In ''Franchise/BeingHuman'' the three main characters are a vampire, a werewolf, and a ghost who still care about humans and are trying to live as normally as they can.
* This happens a couple of times in the new ''Series/DoctorWho'':
** This happens a lot with Cybermen who haven't been 100% perfectly converted.
*** In "Doomsday," converted Torchwood head Yvonne Hartman shoots a bunch of Cybermen while [[MadnessMantra repeating]] "I did my duty for queen and country...I did my duty for queen and country..."
*** Cybermen who resist orders in the Series 8 finale include [[spoiler: Danny Pink and TheBrigadier.]]
** Similarly, [[spoiler:Oswin Oswald]] and [[spoiler:Tasha Lem]] resisted Dalek conversion and helped save the day.
** In "The Pandorica Opens", Rory Williams' UnexplainedRecovery as a Roman soldier despite being [[{{RetGone}} erased from history]] is discovered to be because he was ''[[TomatoSurprise really]]'' an Auton duplicate and ManchurianAgent implanted with Rory's memories. Despite being forced to shoot Amy when his programming briefly took over, his genuine love for her allowed him to break his programming and he vowed to spend the [[TheSlowPath next 2000 years]] protecting the Pandorica with Amy inside until she could be safely revived. [[{{Determinator}} And he did]].
* ''Franchise/KamenRider'' series does this as a tradition. At the very basest level, in every series the Rider's powers are somehow connected the bad guys (most often in the form of stolen technology), but the hero chooses to use his powers for good rather than evil.
** The Showa-era shows (1971-1989) were about ordinary people being subjected to UnwillingRoboticisation by evil organizations or cults, only to escape with their free will intact and use their newfound powers to protect humanity. The few exceptions are [[Series/KamenRiderV3 V3]] and [[Series/KamenRiderStronger Stronger]] (who willingly became cyborgs so they could fight the bad guys) and [[Series/KamenRiderAmazon Amazon]] (whose powers come from a {{Mayincatec}} artifact).
** In ''[[Series/KamenRiderFaiz Kamen Rider 555]]'', Orphenochs are supposedly the next evolution of mankind, and the evil organization forces them to attack normal humans (in hopes of siring more Orphenochs. However, about one in a hundred can be transformed; most just ''turn to dust.'') Some just go nuts on their own. However, there's a trio of renegade Orphenochs living together ''Franchise/BeingHuman-''style. The Rider suits were created by the bad guys, but are not themselves part of the transformation, though for the main Rider, [[spoiler: it turns out there's a very good reason he can use a TransformationTrinket that isn't supposed to work for humans.]]
** In ''Series/KamenRiderGaim'', [[spoiler:both Kouta and Kaito end up willingly becoming Overlord Invase in their pursuit of the Golden Fruit. When Kouta wins, he TakesAThirdOption and sends [[AlienKudzu the Forest of Helheim]] to a remote planet on the edge of the galaxy, sparing humanity from near extinction. Though Kaito acted as a SocialDarwinist for much of the show and followed a different path than Kouta, he was still well-intentioned and wanted to help humanity.]]
** In ''Series/KamenRiderExAid'', [[spoiler:Kiriya Kujo is killed fairly early in the series by Kuroto Dan, and much later on he's revived as a Bugster (essentially a living computer virus). While it looks like he's undergone a FaceHeelTurn at first, it turns out he was just faking it, and jumps ship to the good guys as soon as he steals something important away from the BigBad. Kuroto is also killed and resurrected, but remains [[{{Jerkass}} a complete prick]] with a major [[AGodAmI God complex]]; technically he's on humanity's side, mainly because he hates the other side more. Together they end up developing an important vaccine that helps bring down the BigBad, and at the end of the series they're still Bugsters and still with the heroes.]]
* ''Series/TeenWolf'' does this. Scott. He cares deeply for humans and innocents, even trying to protect the Argents when possible. In contrast Derek is fine offering the "gift" of Lycanthropy to those who crave it, outcasts, the ones who are emotionally damaged and with health problems. Scott is particularly upset at this because of the active hunting werewolves face, making that much more likely the new converts die... Assuming they don't kill someone first.
* ''Series/TheVampireDiaries'' has Stefan. Even though he is a vampire, he still tries to retain his humanity as much as possible.
** Elena as a vampire. She still retains her compassion and empathy even after she turned.
* ''Series/{{Supernatural}}'' has [[SoullessShell Sam when he was temporarily soulless]], he still dedicated his life to hunting (though [[ShootTheDog a bit]] [[TheUnfettered differently]]) and still seemed to care about pleasing his brother.

[[folder:Tabletop RPG]]
* [=MasterBook=] RPG ''The World of Species'', based on the film ''Film/{{Species}}''. Humans are injected with some of Sil's DNA, causing them to gain some of her abilities. This allows them to hunt down and destroy Sil's progeny, but they have alien thoughts and personality traits generated by the DNA in their systems.
* ''TabletopGame/DungeonsAndDragons'' supplement ''Knight of the Living Dead''. A lich brings a paladin of Torm back from death as an undead creature. The lich orders him to gather magic items to help the lich conquer the city of Waterdeep, but instead he decides to fight against the lich's forces and protect the inhabitants of the city.
** Especially in the d20 fork, there are a lot of transhuman options (of varying degrees of alteration from the base norm) available for good characters (good, of course, being by its nature opposed to a lot of the classic symptoms of a SuperSupremacist).
* In ''TabletopGame/{{Warhammer 40000}}'', every SpaceMarine is a bioengineered Transhuman, yet they serve humanity with zealous ferocity. It helps that the transformation, and the very reason they exist, is explicitly to protect humanity better. Of course their methods of protecting humanity include ruthlessly exterminating anything that isn't human. [[note]]Of course, they also gleefully exterminate humans that oppose the Imperium (heretics!) or those too deviated from the holy human form (mutants!).[[/note]]
** It does actually vary by Chapter to Chapter on whether they're the protectors of humanity or the executioners of the Emperor's enemies. Some of the nicer Chapters including the Ultramarines (who run a LawfulGood and comparatively pleasant sector of the Imperium), the Space Wolves (who pulled an ''epic'' WhatTheHellHero on the Inquisition and actually had a small war with them at one point over it), the Raven Guard (who will save ''everyone'' or die trying due to their TearJerker past), and the Salamanders (who are the only chapter who actively protect civilians, making them something of an EnsembleDarkhorse in the fandom) count especially as this trope. The [[SociopathicSoldier Flesh Tearers]] and [[SmugSuper Marines Malevolent]], and ''especially'' the [[EvilCounterpart Chaos Space Marines]], however...
** [[DeconstructedTrope Deconstructed]] with the Emperor himself. An astonishingly powerful psyker verging on PhysicalGod, the Emperor was essentially on the side of humanity...[[FantasticRacism at the expense of all other species]], meaning that the Great Crusade was as much a war of extermination as it was an attempt to protect human worlds. Additionally, his vast power and long lifespan meant that he had great difficulty relating to the people he depended on to run his great empire, which led to a rift developing between himself and the Primarchs that ended in fully half of them betraying him and setting off a civil war that would ultimately burn the Emperor's goals to ash.
* Virtually everyone who's not a "flat" (unaugmented human) is some shade of this by default in ''TabletopGame/EclipsePhase''. Not much of a choice since the vast majority of those who survived the hard-takeoff {{Singularity}} were transhumans (and the harsh realities of the setting will ensure that they stay the majority no matter what anyone has to say about it); in fact, the setting refers to ''trans''humanity. Though there are exceptions such as the Exhumans (in particular the [[ImAHumanitarian Predator]] sub-faction) and the {{U|bermensch}}ltimates.
* The Carthian Movement from ''TabletopGame/VampireTheRequiem'' aren't exactly advocates ''for'' humanity - some of their plans for alternative models of vampiric government rely on a steady supply of "cattle" - but of the various Covenants, they're the ones most likely to advocate for human ingenuity, believing that human models of civilization will point to a grand replacement for the standing model of praxis. One of their more radical factions, the Anti-Obstructionist Army, actually takes action against anyone who tries to Embrace a human, claiming that human thought is hampered by the [[CreativeSterility somewhat cooling effect]] of becoming a vampire.

[[folder:Video Games]]
* The ''[[Franchise/GodEater God Eater]]'' series features this trope more subtly in the form of the titular God Eaters. In order to use their God Arcs and defend humanity, they need to be injected with Oracle Cells that effectively turn them part Aragami. Otherwise, they would not only lack the strength and endurance needed to fight said Aragami, but would also literally be eaten alive by their own weapons. The use of a [[FantasticDrug powerful drug called Bias Factor]] is the only thing keeping them from transforming fully into the same monsters they fight.
* Sergeant Tarkus from [[VideoGame/DawnOfWar Warhammer 40K: Dawn Of War II]], to the point where he has the FanNickName of "Grim Dark Kenshiro" by 1d4chan.
* In ''Videogame/{{Bioforge}}'' the MadScientist hoped that you would succumb to TranshumanTreachery after he upgraded (and deformed) you, but instead made you into a vengeful PhlebotinumRebel.
* In ''VideoGame/SidMeiersAlphaCentauri'', eventually you gain the technology to turn your people into transhuman "transcendii," who are basically energy beings via BrainUploading. They're still loyal citizens, each and every one.
* If one plays through ''VideoGame/DeusExHumanRevolution'' with a pacifist slant, this is how protagonist Adam Jensen identifies himself in [[spoiler: any of the four]] endings. After all, [[MemeticMutation he never asked for this]]. He does, however, admit that augmentation can be ''very'' beneficial.
* In the original ''VideoGame/DeusEx'', this advocacy is exactly why the Helios AI wants to fuse with [[PlayerCharacter J.C. Denton]] instead of [[CorruptCorporateExecutive Bob]] [[BigBad Page]]. Page is a power-crazed tyrant bent on world domination who would oppress and subjugate. JC has been a staunch proponent of the people, and Daedalus, an aspect of Helios, had been watching the entire time. The "Pro-Human" aspect of JC is what Helios wants, to understand the human condition so it can better function as a benevolent machine god ruler. Helios knows enough about humans to know Bob Page is emphatically ''[[TranshumanTreachery not]]'' a good choice for this. One of the three endings for the game involves JC volunteering and doing just that.
* In ''VideoGame/MassEffect3'', [[spoiler: if [[PlayerCharacter Commander Shepard]] chooses to control the Reapers in the ending, Reaper!Shepard - especially a Paragon one - vows to use them as a force for good.]]
** Technically, Paragon Shepard became Transhuman during the second game, having been resurrected with cybernetic implants, as well as undergoing extensive genetic modification that not only gives them increased speed and stamina, but resistance to small arms fire and strong enough to wield weapons that when fired, would normally shatter every bone in a normal person's arm. Shepard is a Pro-Human Transhuman in either case; paragon Shepard is a hero who protects all sentient life in the galaxy, while renegade Shepard [[FantasticRacism helps humans and nobody else.]]
* In ''VideoGame/DragonAgeOrigins'', part of the Joining Ritual to become a [[BadassArmy Grey Warden]] involves ritually drinking Darkspawn blood, where the Wardens willingly submit themselves to [[TheCorruption the Taint]], becoming immune to its effects [[spoiler: ([[YourDaysAreNumbered for thirty years]])]], gaining the ability to [[MySignificanceSenseIsTingling sense the Darkspawn]] and rendering them the only ones capable of truly slaying an Archdemon, thus ending the latest Blight.
** [[spoiler: [[HumanoidAbomination The Architect]]]] in ''VideoGame/DragonAgeOriginsAwakening'' qualifies, although technically he's [[spoiler: a TokenHeroicOrc]] who is not so much concerned with preventing further Blights to help humanity as much as he desires to [[spoiler: free the Darkspawn from the influence of the Old Gods.]] However, he's not been particularly successful so far, since the last time he tried to help [[spoiler: he ended up accidentally ''causing'' the Fifth Blight.]]
** On the other hand, the reason the Circles of Magi exist is because the Chantry, as well as a good chunk of the population, do not believe that mages can be reliably Pro Humans. This is mainly because of the [[TheMagocracy Tevinter]] [[TheEmpire Imperium]], which is ruled by powerful mages, and controlled much of Thedas centuries before. In fact, according to Chantry teachings, the Tevinter mages are responsible for creating the Darkspawn. There's also the little fact that every mage is a potential conduit for evil spirits of the Fade to enter the world.
*** A good example of a Pro-Human mage would be the father of [[VideoGame/DragonAgeII Hawke]] who taught his mage children to use their powers responsibly and had his own BadassCreed where he reminded himself that his magic would "serve that which is best in (him), not that which is most base." Mage player characters can be this as well... or not.
* In ''VideoGame/TheElderScrollsVSkyrim'', the Dragonborn is a mortal with the soul of a Dragon, prophesied to protect Mankind by [[TheDragonslayer hunting down]] and [[YourSoulIsMine consuming the souls]] of Dragons.
* The player characters Vent and Aile in ''VideoGame/MegaManZX'' are, like most people in this period, crosses of human- and Reploidkind, and fight to protect everyone. In the [[VideoGame/MegaManX earlier series]], Dr. Light is this, having become [[BrainUploading an infomorph]] and continues protecting humanity through aiding his "son" X.
** In the AlternateTimeline of ''VideoGame/MegaManBattleNetwork'', [=MegaMan.EXE/Hub Hikari=], an infomorph in the form of a Net Navi, is fully pro-human.
* All of demigods in ''VideoGame/AsurasWrath'' are transhuman cyborgs, but Asura is the only one after 12,000 years that stands up against them for humans after they start slaughtering them to obtain their souls for more power.
* In ''VideoGame/WarcraftIII'', Night Elf warlock Illidan Stormrage seeks demonic powers to prove himself to his skeptical brother and sister-in-law and ultimately fights against the genocidal undead Scourge. By the time of ''VideoGame/WorldOfWarcraft'' [[TranshumanTreachery he's turned evil]].
** To be fair, his track record includes being subjected to rejection, distrust, betrayal, ten thousand years of incarceration, distrust and rejection... And even at that point, it was because he had no one to turn to when meeting Kil'Jaeden, that he '''at long last''' started his descent into darkness. It took meeting BigBad while being systematically deprived of freedom, support and hope ''by the woman he loved and by the brother he trusted'' to get him to turn. DespairEventHorizon and DarkestHour at their worst. And even then the task he accepted was arguably beneficial to the world of Azeroth - to destroy The Lich King, and he specifically attempted to turn away from Kil'Jaeden and create a place for himself after his first attempt failed.
* In ''VideoGame/{{Crysis}} 2'', humanity's best chance at fighting off an alien invasion is a DeadManWalking, kept alive by a semi-intelligent suit of PoweredArmor [[spoiler: based on [[ImportedAlienPhlebotinum Ceph nanotechnology]]]].
** Taken even further in ''VideoGame/{{Crysis}} 3'', where a protracted nanotech FusionDance has you playing as [[spoiler:an amalgam one dead guy's body, another dead guy's personality, and both of their memories, with an artificially intelligent suit of PoweredArmor holding it all together.]] You're about as transhuman as it gets, but still firmly on the side of humanity and more badass than ever.
* In ''VideoGame/InfinityBlade'', [[spoiler: the Deathless are revealed later in the series to be normal humans from a bygone era, who technologically altered their [[OurSoulsAreDifferent Q.I.P.'s]] and bodies to make them immortal, permanently at their physical peak, and grant them superhuman power. In the second game, it's revealed that Siris, the main character, is actually the Deathless Ausar [[TheDreaded the Vile]], who lost his memories and lived on amongst normal humanity, but this fact doesn't stop him from fighting for humanity's freedom.]]
* Keine Kamishirasawa of ''VideoGame/{{Touhou}}'' is a [[OurWerebeastsAreDifferent were-hakutaku]] who's described as the safest person for a human to be around.
* Mr. House in [[VideoGame/FalloutNewVegas Fallout: New Vegas]] is this in spades. [[spoiler: While he claims to be “flesh and blood, not silicon,” he projects his will through a brain-computer interface into an army of robots, all of which are functional extensions of his body when they’re close enough to the Lucky 38, and any Courier who turns against him will probably see the [[WasOnceAMan extent]] of his cybernetics. And his ''stated'' [[GratuitousFrench raison d'être]]? Nothing less than “[Give me] 100 years, and my colony ships will be heading for the stars, to search for planets unpolluted by the wrath and folly of a bygone generation.” He’s as cold as you like, but he does want to save humanity (though he [[HobbesWasRight doesn’t respect most of it]], much less trust it to [[DemocracyIsBad govern itself]]).]]

[[folder:Visual Novels]]
* Gilgamesh of ''VisualNovel/FateStayNight'' was created by the gods of his time to tie them to humans, ensuring the continued existence of the gods. Gilgamesh eventually came to love humans more than the gods and rejected his role in the gods' plan, choosing to rule over Uruk because it was worth ruling. Even Gilgamesh's attempts to [[spoiler:unleash Angra Mainyu on humanity]] is driven by his belief that the best humans will survive and be worth ruling.

[[folder:Web Comic]]
* People in ''Webcomic/CrimsonDark'' with lots of [[{{Cyborg}} augs]], despite often [[HollywoodCyborg being less than 20% flesh]], still act just like normal humans.
* ''Webcomic/TheKingfisher'': Vampirism doesn't make one inherently evil, but the pro-human vampires are few: mainly Helen, Vitus, Jack, Tristan, and Darren. Notably, some of the least powerful characters in the story.
* ''Webcomic/GenocideMan'': Genocide Men believe that they are such, except maybe for Joey, using their ceramic skeletons, artificial glands, and suitcases full of ebola to hunt down and exterminate genetic deviants for the good of humanity. Though there are signs that their philosophy is flawed, [[spoiler: and they turned most of the planet into deviants themselves in an attempt to make people immune to designer plagues and less violent, with a virus that killed over a billion people.]]
* The Bowman's Robots from ''{{Freefall}}'' arguably fit into this trope as a whole. Despite being designed as expendable labor, and the evident fact that no ammount of hard-coded safeguards can stand up to the full sapience they (accidentally) wound up with, they still want nothing more than to be of use to humanity. One (minority) faction even believes that the best way they can do so is by wiping themselves out wholesale, not just to ensure that they ''never'' become a threat to humanity, but also because the absence of adversity humanity would be stranded in, surrounded by millions upon millions of eager-to-serve robots capable of independent thought and action, would sap mankind of any philosophical impetus to continue pushing the boundaries of the cosmos - essentially rendering humans 'obsolete' amongst the hardier, faster-replicating robots, no matter how benevolent they may be.

[[folder:Web Original]]
* The Sephirotic Archailects and their ancestors, the early pro-human transapients, from ''WebOriginal/OrionsArm'' are this. The Archai are not specifically pro-''human'' as such (humans are but a fraction of the 10th millennium terragen populace), but generally benevolent towards lower toposophic lifeforms and promoters of sophont rights regardless of singularity level. This is as opposed to the solipsist [=AI=]s, who just don't care about anyone else positively or negatively, or the ahuman [=AI=]s who will, at best, kick lower beings off of their turf, or, for the less fortunate, MindRape them to death or [[FateWorseThanDeath worse]].

[[folder:Western Animation]]
* In ''WesternAnimation/JusticeLeague'', Gorilla Grodd intends to publicly kill the League because they are Transhumans fighting to protect humans, which, according to him, is contrary to natural selection.
* The female lead hero ''WesternAnimation/CyberSix'' from the animated show of the same name. While pretending to be a "normal" human by day and "becoming" the hero Cybersix and fighting monsters by night.
* [[WesternAnimation/CasperTheFriendlyGhost Casper the Friendly Ghost]] is ExactlyWhatItSaysOnTheTin. Most other ghosts in the franchise are mean and just want to scare people.