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- The Lost Light in Transformers: More than Meets the Eye is seen as being as much a character as any of the crew. Which makes it all the more distressing when, in the season 2 finale, Getaway and his mutineers steal it and strand the crew on Necroworld. Season 3's plot revolves almost entirely around chasing Getaway down and getting it back.
- Back to the Future Franchise - The destruction of the DMC time machine at the end of the third film has been known to cause some viewers to shed a tear or two.
- Star Trek: The Original Series" - The Search for Spock'' - When the original Enterprise burned up over Genesis, Star Trek fans cried the world over.
- Star Trek: Generations - Essentially the same thing with the Enterprise D. That's what happens when you let Troi drive.
- Chitty Chitty Bang Bang - This instance of the trope is not so much the fault of the audience as it is the fault of the main characters who endow Chitty as a character themselves. One may notice that the characters only take it so far; for example, they never refer to Chitty as 'he,' only as 'it.'
Live Action TV
- Airwolf - The Airwolf Helicopter played such a crucial role in the series that even the main characters routinely endowed it and endeared it as a character all its own.
- Firefly - If Serenity didn't exist, then those space cowboys would have nowhere to go. The characters themselves treat her as part of the crew, as does director Joss Whedon: Serenity is described in director's commentary as the tenth member of the crew, in the context of a comment about the eleventh member being Summer Glau's feet.
- Supernatural - The Winchester's Impala. So much so that the framing story of the season 5 finale was the biography of that car, treating it as the most important thing in all creation.
- Star Trek: Voyager - USS Voyager. In the Year of Hell episode, Captain Janeway even considers Voyager as family, equal to the rest of the crew.
- This has been true of the TARDIS in Doctor Who for years. You can actually see a gradual process of treating it as a simple "capsule" to the Doctor's longest, truest companion over the length of the series. Then, finally, we got to meet her, and it was one of the most tear-jerking, heartwarming episodes ever.
- In MegasXLR Coop seemed to care about his giant robot like it was alive, even saying he loves it.
- In Steven Universe, Lars realizes that Emerald feels this way about her ship, the Sun Incinerator. She's so obsessed with chasing down the Off-Colors because, to her, they weren't just stealing a ship for transport, they were stealing her best friend.