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Anime & Manga
- In the animated version of Ginga Densetsu Weed any time a character has their ear bitten off, it's a pretty sure sign their death is coming up pretty soon.
- Death Note. Anyone whose name is written into the Death Note is marked to die after a period of time.
- Humans have an allotted time to live that is displayed above their heads when viewed through the eyes of a Shinigami.
- In the Astro City mini-series, The Dark Ages, a character is marked for death by the vigilante Blue Knight by the appearance of a crosshairs on the back of his neck.
- In X, this is X's trademark. A single diagonal slash across your face meant that you were warned and you'd better not break his rules again; if he completed the X, he killed you. No exceptions.
- Pirates of the Caribbean: Dead Man's Chest: A character was marked with a literal black spot on his hand.
- The creatures in the horror movie They mark their victims with a dime-sized sore that houses a long, thin bone. This mark is used to track their victims down when the creatures are ready to eat.
- In The Frighteners, a number appears on the forehead of the person that the reaper is going to come after.
- The Final Destination series is pretty much built on this trope.
- Photos of characters slated to die in The Omen (1976) showed strange marks indicating the imminent cause of death.
- L: change the WorLd: After writing his name in the Death Note at the end of the live action Death Note movie, L has 23 days left to live. Using that time to solve cases, L is essentially invincible until his time runs out.
- In Treasure Island, Billy Bones receives "The Black Spot," which means he's about to die.
- Happens in a few Stephen King books. In Insomnia, Ralph is able to tell when people are about to die when they are surrounded by a black "deathbag". In Doctor Sleep, Danny has visions of flies crawling across a person's face when they are about to die or have a serious illness.
- In King's The Dark Tower series, when a Ka-Tet is about to end, they feel Ka-Shume, a sense that the parting of ways is coming.
- The Last Dragon Chronicles: Ms.Gee, literally, by Hannah. Hannah threw her dead ancestors hand at Ms.Gee, and she caught it, dooming her to a horrible death.
- In a third season episode of Criminal Minds, the victims all appear on "Have You Seen Me" posters before they disappear.
- Doctor Who:
- "The Curse of the Black Spot", anyone whose blood is drawn on the pirate ship has a black spot appear on their arm, and is promptly lured in and then disintegrated by a siren. It's subverted in the end: the "siren" is an advanced medical hologram, and the disintegration actually teleports them into a spaceship's sickbay.
- In "Face the Raven", a minor character receiving one of these - a tattoo of a number which keeps changing, counting down the minutes until his death - drives the plot of the episode. Clara takes the mark onto herself partway through to free the original victim from it; unfortunately this turns out to make the mark impossible to remove and she dies at the end of the episode.
- Agent Demetri Noh in FlashForward (2009); while everyone else has seen visions of themselves six months in the future, he has not, a strong indicator that he doesn't live that long.