History Main / MarkOfTheSupernatural

* Kukuru from ''Animation/FlowerFairy'' typically has blue eyes, which are only noticeable when he's in his more human-looking forms and not his SuperDeformed shape. When he's [[spoiler: possessed by the evil fairy Princess Fannie]] in Season 3, his left eye turns red.

* In ''Literature/TheShadowhunterChronicles'':

* In the Creator/RogerZelazny book ''Literature/ThisImmortal'', protagonist narrator Conrad Nomikos has heterochromia, among other odd features. But then he [[spoiler: is probably a mutant and is definitely hundreds of years old.]] His unique appearance is an important plot point.

* In ''A World of Wonder'', TheChosenMany are called "the Runed" because of the tattoo-like symbol of [[PlayingCardMotifs a card suit]] people [[spoiler:and animals]] gain after chosen by a caterpillar. Gabriel has the heart on his left palm, Renata has the spade on her chest, and [[spoiler:Professor Chimes has the diamond on his back.]]

* ''TabletopGame/WarhammerFantasy'': Mutations are almost always a sign of Chaos in a newborn, but where these signs are welcomed as a blessing of the Dark Gods in Norsca ({{Literature/Wulfrik}} was born with wolf fangs instead of human teeth, Sigvald with a horned birthmark), they're widley feared in the Empire (and not without reason) and the children killed, abandoned or worse. Sometimes the mark comes later in life, in the Empire the victims pretty much have two fates left: be killed by a screaming mob, or escape into the forests and become a slave to Beast-men herds by showing them their village.

* In the ''VideoGame/CommandAndConquer'' Tiberian series, people who have survived Tiberium exposure and have become mutated have green Tiberium crystals embedded in their bodies. They are often referred to as "shiners" because of the way the crystals glow.
* In ''VideoGame/DarkSouls'', the Undead are all branded by the "Dark Sign", a small, circular mark with what appear to be tiny flames coming off of it. Where the Dark Sign came from and why it exists are some of the driving questions of the series: it appears to be a force of nature. Undead afflicted by it do not turn evil... most of them are just regular folk; good people, bad people, stupid people, etc. However, as time goes on, and they "die" more and more, they gradually lose their minds, until they become "Hollow", a state in which the Undead has lost all humanity and reason, and mindlessly attacks anything that comes near. There is no known cure for it, though many in the series search for one.
** ''VideoGame/DarkSoulsIII'' finally gives us an answer on where the Darksign came from in ''The Ringed City''; [[spoiler: it was created by Lord Gwyn as a "seal of fire" meant to deny mankind of their innate access to the power of the Abyss and the Dark Soul. Thus cut off from that which makes them what they are, the dark began manifesting itself as the Undead curse in those with little Humanity, and as an all-consuming power that drives those possessed by it stark raving insane for those with too much, and the lack of control over their souls compared to bearers of light souls only made the problem worse for mankind.]]

* In the original ''VideoGame/{{Fable|I}}'', the most magically powerful characters gain ProphetEyes and glowing patterns under their skin. The wizard Maze has had his develop to the point of VolcanicVeins.

* The omnipotent protagonist of ''WebOriginal/NothingLikeTheSun'' has [[GlowingEyes eyes that glow like the Sun]]. This trait is inherent to her powers, because when she makes her best friend omnipotent too, the friend's eyes start glowing as well.

* Those possessed by demons in ''Webcomic/TheGreenhouse'' eventually develop a permanent physical tell. For main character Mica, it's CuteLittleFangs that get more pronounced as the story goes on. For [[spoiler:love interest Liv]], one of her eyes can turn red. This becomes [[ChekhovsGun useful later]] when [[spoiler:Mica is separated from Red and [[LaserGuidedAmnesia loses all memories of her]] in the process. Her CuteLittleFangs are the only physical proof she has that she's not completely losing her mind]].

* In ''Literature/TeaWithTheBlackDragon'', Mayland Long is a dragon who has become human. The main sign of his strange origin is his hands, which are unusually shaped, with very long fingers. Most of the people who pay enough attention to him to notice find them disconcerting; Martha merely comments that with hands like that he has the potential to become an remarkable piano player.

* In ''VideoGame/FireEmblemAwakening'', the royal family of Yllise has the Mark of Naga on their bodies, distinguishing them as the wielders of the legendary sword Falchion [[spoiler:and who can awaken its power via the Awakening ritual]]. Chrom has the mark on his shoulder, while Emmeryn has it on her forehead. [[spoiler:Lucina, Chrom's daughter, inherits the mark as well, which is located in [[MagicalEye the iris of her left eye]].]]

* Pictured above is Belldandy from ''Manga/AhMyGoddess''. Goddesses and Demons have respectively blue or red facial markings on their foreheads and cheeks, with different shapes symbolizing their ranks. At one point Belldandy is temporarily turned into a demon and [[GoodColorsEvilColors her blue marks are replaced by red ones to reflect that]].

* In ''Literature/SomethingMoreThanNight'', Stephen Swift's right eye is dramatically bloodshot, a consequence of a past incident when she [[PsychicNosebleed overused her telekinesis]]. She usually hides it behind PeekABangs. [[spoiler:When Ward Home Junior steals her telekinesis, he immediately gets the bloodshot eye as well.]]

* In ''LightNovel/OthersidePicnic'' Sorawo's and Toriko's encounter with the kunekune leaves their bodies permanently altered. After Sorawo looks at the kunekune long enough to perceive its true form (and almost loses her mind in the process), her right eye [[EyeColourChange turns a vivid shade of blue]] and [[MagicalEye gains the ability to perceive the true form of all Otherside phenomenon.]] Toriko, who pulled off the strange growths that appeared on Sorawo's face, ends up having her left hand gradually turn completely transparent, gaining the ability to physically interact with Otherside phenomenon. Combining their abilities gives them a fighting chance against all the strange threats from the Otherside.

* Kukuru from ''Animation/FlowerFairy'' typically has blue eyes, which are only noticeable when he's in his more human-looking forms and not his SuperDeformed shape. When he's [[spoiler: possessed by the evil fairy Princess Fanny]] in Season 3, his left eye turns red.

** A notable trait of those characters like hailing from the [[SoiledCityOnAHill fallen nation]] of Khaenri'ah, once a high-tech {{Shining City}} [[HumansAreSpecial independent of any of Teyvat's gods]] or the control of Celestia, but was [[GodIsDispleased destroyed by the Heavenly Principles]] and [[LookOnMyWorksYeMightyAndDespair left in ruins]] are their four-pointed cross-shaped pupils in {{Icy Blue Eyes}}. These are most clearly seen in Mondstadt's {{Lovable Rogue}} and Knights of Favonius cavalry captain Kaeya Alberich, and also in eyes of the former Khaenri'ahn royal guard Dainsleif who has been [[WhoWantsToLiveForever cursed to immortality]] as part of Khaenri'ah's divine punishment.

* A notable trait of those characters like hailing from the [[SoiledCityOnAHill fallen nation]] of Khaenri'ah, once a high-tech {{Shining City}} [[HumansAreSpecial independent of any of Teyvat's gods]] or the control of Celestia, but was [[GodIsDispleased destroyed by the Heavenly Principles]] and [[LookOnMyWorksYeMightyAndDespair left in ruins]] are their four-pointed cross-shaped pupils in {{Icy Blue Eyes}}. These are most clearly seen in Mondstadt's {{Lovable Rogue}} and Knights of Favonius cavalry captain Kaeya Alberich, and also in eyes of the former Khaenri'ahn royal guard Dainsleif who has been [[WhoWantsToLiveForever cursed to immortality]] as part of Khaenri'ah's divine punishment.