"He's a mad scientist and I'm his beautiful daughter."A traditional character, although something of a Discredited Trope these days: a Mad Scientist almost always has only one child — a beautiful but innocent girl in her late teens or early twenties, who loves her father dearly, and whom he has kept cloistered away from the world. Sometimes she has some small doubts about his goals or methods. When the question of how a shriveled ugly man has a gorgeous daughter comes up, the response is sometimes "she looks like her mother." Or sometimes because he looked better in his youth. When the Mad Scientist is a good guy, the Daughter is not nearly so cloistered, although she is still a prime candidate as a love interest. Sometimes she ends up The Chick or The Smart Girl in a Five-Man Band when a team relies on the Scientist for their Phlebotinum. This latter version is more common nowadays. This trope is Older Than Feudalism, Medea — and many Fairy Tale heroines — being a recognizable form of it, even if it's the mad wizard's beautiful daughter. Often overlaps with The Ugly Guy's Hot Daughter. May overlap with Daddy's Little Villain.
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Anime & Manga
- Tenchi Muyo!:
- Ryoko, daughter of Washuu, is anything but cloistered or innocent. The mad scientist in question is her mother, and Ryoko generally refuses to even admit they're related (even though the resemblance could hardly be more obvious) — but she still falls for the hero.
- As it is, her mad scientist mother falls for the hero as well.
- Some adaptations of Tenchi do have Ryoko rather scared of her mother because she likes using her as a guinea pig.
- Sailor Moon:
- Professor Souichi Tomoe, the Mad Scientist of the third season, has a beautiful young daughter named Hotaru. Who actually happens to be a) possessed by Mistress 9, the season's Dragon, and b) unknown even to herself until the end, the heroic Magical Girl Sailor Saturn. (Oh, and she's also about twelve years old. Most of the time. And in the manga, a cyborg. She becomes fully human later though)
- Hotaru is a slight subversion as she's only around 12 when she's introduced her being reborn as an infant and later grows up to around this age, but appears younger (possibly due to change in art style in the last season) complicates her real age. However when she's possesed by Mistress 9 her body grows up into a beautiful young woman.
- In the continuities where Juuzo Kabuto is crazier, Kouji Kabuto from Mazinger Z fits like the Mad Scientist's Cute Grandson.
- Lorelei -a secondary character from Shin Mazinger Shiro got a crush on- also fits.
- Lisa, on the other hand, subverted it. Her father -Professor Gordon- was completely sane.
- In Romeo X Juliet, Romeo Condore Van diMontague is the son of the dictator of Neo Verona, the ruthless Leontes Montague, as well as the love interest of Juliet Fiamatta Errs diCapulet, the long-lost heiress of the Capulets. Actually, there are two Mad Dictator's Handsome Sons: one is Romeo and the other is his half-brother Tybalt, who is still Juliet's cousin since his mom was a Capulet. Or three, if we count Mercutio... Dude, that's one messed-up family tree.
- Aina Sahalin in Mobile Suit Gundam: The 08th MS Team is the Mad Scientist's Beautiful Sister, as well as the test pilot for her brother Ghinias's doomsday device. She eventually decides to turn against him when he goes full-on underpants-on-head crazy and starts shooting at her for trying to negotiate a truce.
- The original Mobile Suit Gundam inverts this with the aging leader of Zeon Degwin Zabi, who's fairly reasonable for a tyrannical dictator with a shady past, at least compared to his more handsome son Gihren, who's basically a space Nazi. In the end, Degwin attempts to surrender to the Federation, and Gihren wipes him out along with half of the Federation's forces with the Colony Laser.
- From the perspective of "everyone not living in Zeon and consequently fearing the entire Zabi family", Degwin's very pretty looking youngest son Garma is this played straight.
- Athrun Zala in Mobile Suit Gundam SEED is this note-for-note. He tries to deal with the consequences in the sequel.
- Lyrical Nanoha
- Fate Testarossa fits surprisingly well despite being The Dragon in the first season of Magical Girl Lyrical Nanoha. Beautiful but innocent girl? Check. Loves her (equally beautiful) Mad Scientist mother dearly? Check. Cloistered away from world? Check. Betray mother at inopportune time? Check, though she still held out for her mother's redemption after helping in Storming the Castle. Did so because she fell in love with the heroine? Depending on who you ask, small, kinda check or very, very big check.
- Jail Scaglietti from Magical Girl Lyrical Nanoha StrikerS considers his twelve Numbers as daughters, who see him as their father as well. And the whole family have only good looking members. Only five (actually fournote ) of them are Daddy's Little Villains, the other seven pull a Heel–Face Turn after being arrested by the TSAB.
- Played with in Midori Days, where Mad Scientist Shiro Makinoha wants to capture Seiji and Midori so he can experiment on them, and his daughter Nao wants to stop Shiro since she is in love with ... Midori.
- Franken Fran:
- In D.Gray-Man, the Action Girl Lenalee Lee is the younger sister of Mad Scientist Komui, who raised her. Being an active fighter of evil, Lenalee isn't exactly sheltered, but her brother's attempts to protect her Innocence is the stuff of legends; i.e., When all other attempts have failed, he is usually woken up by being told that Lenalee is getting married, which causes him to immediately wake up and starts freaking out about it.
- Ennis of Baccano!, creation and "daughter" of the 1930 arc's Big Bad, Szilard. She does twist it slightly in that she betrays him not for The Hero, Firo (who, at that point, she thought was dead), but for the comic Outlaw Couple, Isaac and Miria. There's also the daughter of Mad Scientist and unapologetic Manipulative Bastard Huey Laforet, Chane Laforet, who falls in love with the Anti-Hero and professional assassin, Claire Stanfield. This ends up being subverted in that Chane doesn't betray her father for him - instead, Huey just hires Claire.
- Neon Genesis Evangelion:
- Ritsuko and Misato, the former of which takes up the mad science herself, but has yet to procreate. Shinji himself may count as the Mad Scientist's Cute-looking Son, depending on your view. One of the few examples to have mad science on both sides of his family.
- Asuka. Beautiful? Check, Smart? Check, Love Interest? Check, Loves Mad Scientist mother dearly? Check. Mother is insane? Check (Unless you call: A) Reattempting an experiment that ATE the previous person. B) hanging yourself (After losing what sanity you had in said experiment) so that your daughter would be the first person to find your body. Sane)
- Although Rei is not biologically related to Gendo, she is very much introduced this way in a more archetypical fashion than any of the above (socially inexperienced quiet girl, the only one Gendo shows anything resembling humanity around, protagonist gets interested in her, gradually comes to doubt Gendo's methods and betrays him for the protagonist, etc.)
- Huge subversion in Mobile Fighter G Gundam. We thought that main character Domon Kasshu was the Mad Scientists's Handsome Son... but he wasn't. Then we thought he was the Magnificent Bastard's Handsome Younger Brother... Guess what. He wasn't. His partner Rain Mikamura, on the other hand...
- Getter Robo's Michiru counts as this in several continuities.
- Star Blazers:
- Dubbing created one of these, with Princess Invidia in the second series, rewritten to be Zordar's daughter instead of a lover. Because of the prevalence of this trope, the change was fairly plausible.
- The Japanese manga omake "The Eternal Story of Jura", about Desslok's daughter. The pretty daughter part of it is played pretty straight; even though she's past the doubting stage about his methods and knows he's evil, she loves him. The betrayal was also done by Jura's mother, not Jura, but Jura condoned it.
- Soul Eater: Medusa's child Chrona joins the heroes, albeit unwillingly at first. They become affectionate towards Maka, and to a lesser extent the other protagonists, but are kidnapped back and driven (more) insane. They do eventually betray Medusa, but remain an antagonist until the end of the series.
- Fullmetal Alchemist: Riza Hawkeye is the Crazy Alchemist's Beautiful Daughter.
- Not to mention Nina. Sure, she is just five and anything but a love interest to the heroes, but she is cute, adorable, adores her State Alchemist Dad who shelters her and maybe would have grown into a very cute young woman if her father hadn't used her for chimera experiments that ultimately doomed her.
- Saiko Waitazuki from Supercar Gattiger, though her father isn't mad, but serves as the team's lead scientist. She, of course, ends up as The Chick in their Five-Man Band.
- Durarara!! has Shinra as the Mad Doctor's Handsome Son. He's... slightly more normal than his father Shingen, but he didn't get away without a screw or two loose.
- Minato Sahashi is a male example, in Sekirei. His mother is the head scientist of the Sekirei Plan, and leaves him innocent and oblivious to her work, as well as the identity of his father. It is, of course, Big Bad Minaka. Higa mistakenly believes the younger Sahashi sibling, Yukari, to be this as well. She's not, and sets fire to his penthouse on her way out.
- Cyborg 009:
- Dr. Isaac Gilmore is child-less, and he subverts this by gaining the Cyborgs as his adoptive children after he stops being a Mad Scientist. And there's the little detail that he was among the mad scientists who created the cyborg team in the first place.
- Also subverted by Cynthia Findor, since her father is doing really crazy experiments but NOT willingly. In fact, Black Ghost kidnapped her to reinforce their intentions to keep Dr. Findor under their thumb.
- Kill la Kill: Subverted with Ryuko, since her father Isshin was a perfectly sane man and the Big Good of the story, despite his eccentric appearance. Double Subverted when it's shown that her mother is Ragyo, who experimented on and threw her away as a child. This also means that Satsuki counts, as well.
- Naruto: It turns out that Mitsuki is the Mad Scientist Orochimaru's Handsome Son. Mitsuki says he respects his parent, but thankfully, doesn't seem to have inherited Oro's twisted personality and madness.
- Tokyo Ghoul has Akira Mado, the stunning daughter of "Quinque Maniac" Kureo Mado. She shares her father's passion for Quinque, and works closely with the Research division in her spare time. She inherited her looks from her late mother, and becomes Amon's new partner and Love Interest after her introduction.
- Ponyo is the prepubescent form of this: a Mad Sorcerer's Adorable Daughter.
- Made In Abyss has Prushka, the adoptive daughter of the White Whistle Bondrewd the Novel. Unlike most examples, her awareness of her father's actions is fairly significant. The degree of isolation that she lives in is enough for her to be incapable of seeing anything wrong with it, though, to the extent of seeing the failed Praying Hands as a tragic necessity and being unbothered when she discovers her father's Cartridges .
- Doctor Sivana, nemesis of Captain Marvel, has a daughter with the painfully obvious name "Beautia"; naturally she sides with the Captain against her father.
- In this case Sivana also has a good/handsome son and an evil/ugly daughter and son, who are perfectly happy to help their dad go up against Captain Marvel.
- Though in more modern works, his handsome son and daughter are portrayed as self-centered, spoiled brats while his ugly, brilliant children are their mother's un-favorites and running their own experiments just to impress their mostly absent father.
- Talia, the daughter of Ra's Al Ghul in the Batman comics. Her loyalty to her father is... complicated. In the comics, it is usually unwavering. She foils his 'destroy the written word' scheme, a lackey shoots her in the leg and the lackey is fed to lions.
- In the video game, Batman: Arkham City, it's played darkly when he makes a move of threatening Batman with her life if he does not kill him. This results her in leaving him after Batman saves her.
- Recently, Sofia Branch turned up in Batman: The Black Mirror as the manager of Gotham's fastest growing bank. Who is Sofia Branch? She's the daughter of Tony Zucco, the killer of Dick Grayson's parents.
- Princess Aura, daughter of Ming The Merciless, in the various versions of Flash Gordon.
- Alicia Masters of the Fantastic Four, stepdaughter of the Puppet Master.
- The Yellow Claw, a Marvel Comics Captain Ersatz for Fu Manchu, had a Beautiful Grandniece, who repeatedly betrayed him due to her love for FBI agent Jimmy Woo. Eventually, he put her in suspended animation until he could fuse her soul with that of a suitably power-mad Egyptian princess. Really.
- Sorta done in Werewolf by Night. When traveling to an island for a cure for his werewolfism, Jack meets the local mad scientist Miles Blackgar and the beautiful daughter Marlene. Marlene helps Jack at first and doesn't even fear him when he's in wolf form, but after he knocks out her father she turns out to have a Gorgon gaze and turns Jack to stone for grabbing her arm. She also seems to help Jack more out of self preservation, since she mentions that her father ultimately intended to experiment on her, to cure her gaze of stone.
- Since Magneto also is a scientist, the Scarlet Witch and her (on and off, currently on) half-sister Polaris qualify. Wanda looks almost exactly like her mother.
- Laura "X-23" Kinney is this. Her creator, Dr. Sarah Kinney, was described as the foremost expert on mutant genetics and was hired by the Facility after her proposal to clone Wolverine. Despite the ethics of the project, Sarah's interest was purely For Science!, directly likening the idea of cloning a mutant, when mainstream science had only just cracked cloning sheep and cats, to godhood. All this knowing full well that the child would be raised to be a Living Weapon heading in. Laura herself is frequently described as Sarah's spitting-image (explained by some writers as Sarah using her own DNA to stabilize the sample taken from Wolverine), and it's made quite clear Laura is intended to be a quite beautiful young woman.
- Dr. Zabo/Mr. Hyde doesn't have much in the looks department (and his inside matches is outside), which is probably why he frequented prostitutes. His daughter, Daisy Johnson/Quake is consistently described as gorgeous, and is one of SHIELD's real lookers, and can't seem to do anything in civilian mode without someone hitting on her.
- Linea in Warlord of Mars is a Black Martian noblewoman whose father is a mad priest of Issus that wants to activate a Doomsday Device that will wipe out all life on Mars (since the defeat of their people at the hand of the Red Martians, he would rather destroy the planet than let themselves be ruled by lesser races). Its revealed that her grandmother was Issus herself, and she qualifies as a Mad Goddess' Beautiful Granddaughter too.
- New Gods: Orion's wife Bekka is the daughter of Himon, the scientist that created the Mother Box and was even forced to work for Darkseid. During the "Death of the New Gods" its implied that he became a Serial Killer and started murdering New Gods left and right, regardless if they were from Apokolipis or New Genesis. Turns out to be a Red Herring, the actual culprit is Infinity Man.
- In The Two Kings' Children, the daughter advises the prince how to carry out her father's Impossible Task.
- Prunella is helped by the witch's handsome son.
- Harry Potter:
- In the French fandom, Voldemort was supposed to have a daughter called Ange (false rumors copied on every fan site). She was rumored to enter Hogwarts in book five. Actually it was one of many false rumors that were copied from one French Harry Potter fansite to another.
- If fanfiction is anything to go by, Voldemort has about a million Mary Sue daughters. It seems he mostly sends them to Hogwarts to kill Harry only for them to (of course) fall in love with Harry. Expect her to show up openly using "Riddle" as her surname with the author acting as though we won't see The Reveal coming a mile away. If it's explained who her mother is, it will probably be Bellatrix.
- For awhile, it was rumored that Snape was Luna Lovegood's father, which would have kind of fit this trope. Too bad the identity of Luna's father was firmly established from the moment of her first appearance. Still J. K. Rowling ended up refuting this on her website.
- Globally subverted in the forum story The Mad Scientist Wars. In the story, the trope is reimagined as the "Mad Scientist's Beautiful Daughter ploy", in which the daughter will always pretend to help the hero escape, then drop him into some even nastier bit of trouble. Apparently, it's hard on the heroes and fun for the daughters.
Films — Animation
- Beauty and the Beast utilizes this with Belle and her father, with alterations in the form of the 'mad scientist' being a good person (more of a Bungling Inventor, really) and the fact that plot starts because the mad scientist's daughter is loyal to him.
- The Nightmare Before Christmas:
- Dr. Finklestein and his beautiful artificial creation Sally. He's smotheringly overprotective, to the point that she has to poison him repeatedly to get a simple night out. Also, Finklestein is actually on friendly terms with Skellington — really, the person he antagonizes most is Sally.
- Interestingly, in an alternative ending, Finklestein being on friendly terms with Jack is subverted with Finklestein being Oogie Boogie, in order to teach Sally about choosing Jack over him, making the Finklestein/Sally relationship seem more carnal. This, along with canonically the next person the Doc creates to replace Sally seems to be a wife (who looks exactly like him and even shares half his brain), has quite a few fans calling bullshit on the "beautiful daughter" explanation.
- For Despicable Me: We have the cutest daughters, Margo, Edith, and Agnes.
Films — Live-Action
- In the 1996 film adaptation of The Island of Doctor Moreau, they give the title doctor a beautiful cat-woman daughter — who conveniently slides into love interest for the hero Douglas.
- Island of Lost Souls started the cat-woman daughter of the mad scientist.
- As the song goes, "Anne Francis stars in Forbidden Planet", based on The Tempest, as Altaira, the Beautiful Daughter of the Mad Scientist, Dr. Morbius.
- Actually a semi-aversion, though, since Morbius specifically denies being a mad scientist, and is ultimately proven to be misguided rather than crazy.
- Occasionally appearing in a Godzilla movie as well, most notable being Katsura from Terror of Mechagodzilla, cyborg daughter of Dr. Mafune. Also, it is worth mentioning that Emiko Yamane, heroine of the original Gojira film, was The Professor's daughter.
- Natalie Connors from Agent Cody Banks fulfills this trope as if the writer had been reading this Wiki.
- Freder Frederson of Metropolis is a Slightly Unhinged Dictator's Handsome Son. Incidentally, the Mad Scientist was in love with Freder's mom.
- In Willow, Sorsha plays the Mad Sorceress's Beautiful Daughter. With some help from a Love Potion and Heel–Face Turn from her mother.
- Tara from Attack of the Killer Tomatoes! fits the trope almost perfectly (right down to the betrayal part), except for having been created by her mad-scientist father to be a cook, house-cleaner and sex-slave. You may squick if you wish.
- Bullshot (1983). Rosemary Fenton, though her father is more of an Absent-Minded Professor who's being forced to work for the villain. She does fall in love with the hero though.
- Cally in Doomsday. Notable mostly because her father's paranoia over her brother's rebellion causes her to fear for her life from him, justifiably as he winds up blaming her for bringing in "impurity". Also notable because the main character is a woman, so Cally winds up a sort of Implied Love Interest for a more minor character.
- Blade. One of the vampire scions helps bring down her house.
- Helen Kokintz in The Mouse That Roared, except that her father is not mad.
- Nanelia in Battle Beyond the Stars is a fairly archetypal example.
- Dione, the daughter of Melanthius in Sinbad and the Eye of the Tiger is an example of the daughter of a good scientist. And he is not really mad, just a little batty.
- Young Sherlock Holmes. Professor Waxflatter is more eccentric than mad, but his daughter is quite beautiful.
- The learned Rabbi of the silent movie The Golem has his beautiful daughter Miriam, who promptly falls in a forbidden love with the christian Knight Florian. Their romance turns out to be a Red Herring Twist, though.
- Amy Szalinski in Honey, I Shrunk the Kids is an example of the daughter of a good guy mad scientist, Wayne Szalinski. However, she's not an only child, as she has a younger brother, Nick, and the sequels include another younger brother named Adam. She is, however, the only girl.
- Elsa Frankenstein from The Ghost of Frankenstein is Dr. Wolf Frankenstein's beautiful daughter. She has a more prominent role as the titular Mad Scientist in the sequel Frankenstein Meets the Wolf Man.
- Kyra in Sinbad of the Seven Seas is the daughter of the Cloud Cuckoo Lander inventor and "wizard" Nadir, and ends up as Sinbad's Love Interest.
- The above two comic book examples both draw elements from Sax Rohmer's Fu Manchu mythos, including the Beautiful Daughter; however, Fu's own daughter Fah Lo Suee was a full-fledged Femme Fatale (or even Vamp) rather than a cloistered innocent — just as likely to turn against him, but because she wanted to take his job....
- A Lampshade Hanging: in Robert A. Heinlein's novel The Number of the Beast, Deety Burroughs introduces her father and herself to her future husband Zeb Carter by declaring, "He's a Mad Scientist, and I'm his Beautiful Daughter." Zeb, in his role as the Narrator, comments immediately on the cliché.
- Hawthorne published Rappaccini's Daughter in 1844. This story has an interesting twist on the trope.
- Though Sloan from the Inheritance Cycle is more Jerk Ass than Big Bad ( though he does betray his village in Book 2), his daughter Katrina might count.
- Philip José Farmer gleefully inverted this trope with "The Beautiful Scientist and her Mad Daughter."
- Children's author Allan Ahlberg wrote a notably creepy poem called The Mad Professor's daughter.
- Subverted in Alexander Belayev's The Air Seller: while Nora Engelbrecht is certainly that trope, her father turns out to be not really mad. He is forced to serve the Big Bad Bayley, who secretly threatens to murder Nora if Prof. Engelbrecht will not help him with his Doomsday Device. At the end, Nora commits suicide to free her father and save the world.
- In the Animorphs series, the Andalite Estrid fits this outline fairly well, although she is only a protege of the Mad Scientist character, Arbat. (Ax speculates that Estrid may be Arbat's niece, but she is no relation at all.) Arbat is a kind of alien General Ripper who intends to deploy a biological weapon (which he designed with help from Estrid) that will destroy both the Yeerks that are invading planet Earth—and probably the human race along with them. When Estrid meets the Andalite main character Ax, they hit it off and she becomes Ax's Girl of the Week. Estrid was initially a Well-Intentioned Extremist who agreed with Arbat's goals, but she became convinced it was wrong and helped to defeat Arbat.
- The First Law plays this straight with Bayaz and Tolomei. Then, in a brutal twist, it is revealed that Bayaz was the one who threw her from the tower, not her Mad Scientist father, in order to hold a monopoly over the secrets which she possessed.
- The heroine of Edgar Rice Burroughs's The Monster Men is the daughter of a mad scientist who is producing the title Monster Men — he hopes to marry her off to one. (He gets better, though.)
- The likeliest "tradithion" to spawn the beautiful Igorinas in the Discworld.
- Heralds of Valdemar:
- The Mage Winds trilogy features Nyara, biological daughter and sexual/magical plaything of Big Bad Ma'ar in his latest incarnation. She "attempts escape" several times, but her Heel–Face Turn doesn't actually occur until Skif nearly dies to save her.
- Lackey's retelling of Swan Lake, The Black Swan, makes Odile into one of these. Her father expects her to betray him, which is painfully ironic since she is a textbook example of a Well Done Daughter Girl — the Heel–Face Turn starts because she starts actually spending time with the swans, instead of just looking down on them. The supernatural control, ie him using her as "Odette" without her permission, is just the last straw that makes her realize his true character. And her turning on him is hardly subtle - she's the one to kill him, after all.
- In A Song of Ice and Fire King Aerys managed to beget a ridiculously good offspring (well, if you don't mind Viserys' mental health). Rhaegar was always in the collective imagination (don't mind Robert Baratheon) the Mad King's handsome and noble son, who'd have made a great king some day. Daenerys is as well a bright young woman who before hitting 16 is already considered World's Most Beautiful Woman and tries hard to not make the same mistakes her family did.
- Elizabeth Faulkner, the daughter of an irrational Elizabethan steam-engineer, in Phra the Phonecian by Edwin Arnold.
- Georgette Cuvelier in Harry Dickson's Adventures. The young woman turns out to be the daughter of Pr Flax, a former archenemy of the hero. Played straight in that she has a huge crush on Harry Dickson. Subverted in that she remains evil and would rather avenge her father and die than surrender.
- Angie Mitchell in William Gibson's Sprawl Trilogy, particularly in Count Zero.
- Played with in Theodora Goss's short story "The Mad Scientist's Daughter," which also namedrops a who's who of iconic Mad Scientists in fiction.
- Andre Caroff's Madame Atomos was a vengeful scientist with a hard-on for radioactive zombies and madness beams. She created a younger version of herself named Mie as a backup plan, who promptly turned on her after falling for Atomos's nemesis, Smith Beffort of the FBI.
- In the short story "The Girl of My Dreams" by Hilary Ayer (a crossover between the Torg and Paranoia roleplaying universes), this is not just a trope, but a law of nature.
Professor Thistlebottam: I was a Scientist, therefore I had to be either Sinister or Mad. I seem to have been cast as Mad, therefore by the laws of the cosm, I had to have a Beautiful Daughter.
- In The Bride of the Wind, the eponymous character's father was a scientist, and she said to be beautiful, if unique-looking.
- In one of the Schaduw (Shadow) detective/policiers by Havank, a Dutch writer, the eponymous main character encounters the most beautiful young woman he's ever seen. As this happens in a remote castle somewhere in Normandy, she can't be anything but a Mad Scientist's daughter. The guy has engineered spiders to be a bit bigger and powerful (the biggest eats a grown pig in a couple of seconds), but he's disappointed their brains have not kept up. But now this human brain has come walking in ... perfect. The kicker: he's named his daughter Aranea (could have qualified as a Meaningful Name, but she herself tries to keep herself away from his shenanigans).
- Miranda Taligent from the Steam Punk novel The Dream of Perpetual Motion. She eventually goes mad herself.
- More or less gender-inverted in Mistborn: The Original Trilogy by Elend Venture, who is the handsome but innocent son of Evil Overlord Straff Venture. Ends up Defecting for Love.
- Invoked in Gene Wolfe's "The Last Thrilling Wonder Story": the author is deliberately writing a pulp story, so of course the scientist has a beautiful daughter, and the protagonist knows he will love her before they even meet.
- Subverted in Die Alchimistin. Aura Institoris is certainly beautiful, and kept cloistered in her castle and then at the institute at her father's wish, and her father in an alchemist who is most definitely not all there, and she is (in the beginning) his favorite child, but it turns out that he was maintaining their bond and keeping her away from theyo turns out that Aura's mother was her father's daughter as well.
- In The Reefs of Space, Donna Creery is the daughter of the Planner of Earth, chief executive of the computer-controlled dictatorship which rules Earth, but she's sympathetic to Steve Ryeland, the scientist who's been arrested for reasons he doesn't understand. She eventually helps him escape when he ends up facing a death sentence.
- In Fyodor Sologub's The Poisoned Garden, the Professor's daughter, only called the Beauty, is an example. He uses her to lure young men into his garden and poison them in revenge for his ancestor's death.
- The title institution of The Secrets of Drearcliff Grange School is basically a finishing school that turns mad scientist's beautiful daughters into femmes fatales to help them snag a good superhero (or villain) husband. While the viewpoint character isn't this trope, many of the other students have diabolical masterminds as children.
- In the Angel episode "Guise Will Be Guise", plays this straight - with MAGIC! In order to save Cordelia, Wesley is forced to impersonate Angel and ends up playing bodyguard to an evil Warlock's beautiful daughter. Hilarity Ensues.
- Play straight in Denji Sentai Megaranger which Hinelar had beautiful daughter name shizuka.
- Star Trek: The Original Series:
- Such as Rayna, Flint's "ward" from "Requiem for Methuselah". He was neither evil nor mad, he just didn't want his privacy to be disturbed (and for good reason).
- Inverted in "Conscience of the King", where it is the daughter who is the mad one, trying to protect her accused father (he wasn't squeaky clean either tho).
- And then there's Tora Ziyal from Star Trek: Deep Space Nine, the innocent daughter of Gul Dukat who always tried to give her father the benefit of the doubt. It didn't end well for her: she dies a pretty pointless death at the hands of Dukat's Dragon when even she was forced to accept that her father had run out of excuses for the way he behaved and the decisions he took. Always mentally unstable at best, her death was what snapped the last remaining thread of sanity Dukat had ever possessed.
- Alex on Lost fits this role, giving information learned from her adoptive father to the crash survivors. Different because it was, perhaps, simply a form of teenage rebellion against him, especially his treatment of her boyfriend.
- Her dad isn't really a Mad Scientist (he employs them instead), but Elle from Heroes works too, down to flirting with the protagonist (Peter). Of course, she's pretty damn evil, and her way of flirting is to electrocute him a little bit each day to make him want it, but still....
- Ziva David in NCIS could be considered this, to a point. Her father could be viewed as a Well-Intentioned Extremist but he's more likely just a Jerkass. Gibbs himself points out to Ziva that her father, despite being the director of Mossad, is dirty and sometimes crosses the Moral Event Horizon into pure, selfish evil. Her response? Sometimes she's on his side, sometimes she's on Gibbs... and now she seems to have crossed permanently into Gibbs' camp by quitting Mossad and terminating all contact with dear old dad.
- Fringe: Male example: The series has a female lead and the son of a Mad Scientist who doesn't exactly approve of his father's activities. By the end of season 2 romance between Peter and Olivia is canon.
- Parodied in an episode of The Monkees where they spend the night in a mad scientist's house. Micky opens a door and finds a woman standing there:
Micky: Who are you?
Woman: I'm the doctor's beautiful daughter.
Micky: Well, what do you have to do with all this?
Woman: Nothing, I'm in the sequel.
- Lampshaded in Danger: UXB when Lieutenant Ash delivers a defused bomb to Dr Gillespie and his daughter Susan, who are building a Heath Robinson Machine in their backyard for steaming explosives out of unexploded German bombs. Ash later reports to his superiors on the phone, deriding the device as completely impractical and describing Gillespie as the proverbial Mad Scientist who even has the requisite beautiful daughter — said daughter has of course just entered the room behind him.
- Spooks: Ros Myers isn't exactly sweet or innocent, but she does prove to be the weak link in her father's Well-Intentioned Extremist conspiracy.
- Doctor Who:
- In "The Evil of the Daleks", Maxtible and Waterfield have one innocent, beautiful daughter each: Ruth and Victoria, respectively. Victoria even becomes a companion.
- In "The Web of Fear", Professor Travers has one, Anne Travers, who is also a Mad Scientist herself. She and Victoria appear to bond somewhat over the similarities between their fathers.
- Mad Scientist's Beautiful Granddaughter: Susan Foreman, the first Companion of William Hartnell's Doctor. While she is his granddaughter, they have this exact relationship, and she was obviously intended to fit this trope (until the series began to Grow the Beard and the Doctor became something much, much odder than simply the mad scientist he was conceived as).
- The Eighth Doctor Adventures kind of introduce Susan's mother, in the form of a young girl whom the Doctor adopts who seems to be Gallifreyan. She happens to be named Miranda and happens to have that beautiful-but-sheltered-and-Oblivious to Love thing going on (at first), and the Doctor has a few scenes of doing sciencey laboratory stuff throughout the book.
Myths & Religion
- From Classical Mythology: Medea of "Jason and the Golden Fleece" fame — she is the daughter of King Aeëtes who sets seemingly impossible tasks for The Hero Jason before he can have the fleece. Although Medea herself is evil and out to serve only her own interests; she eventually betrays Jason, too, although not before killing her own brother and her own children. However, she only killed her children intentionally if you rely on the Euripides version of the myth. Earlier versions had it either being an accident, or murder by other people. She also only killed her brother to save Jason from her father. In fact, the only people she didn't kill for Jason, according to the earlier myths, were the princess of Corinth, whom Jason abandoned her for, and the King of Corinth, who died trying to save his daughter.
- Even the Euripides version assigns most of the actual blame for how things worked out to Jason's heroic flaw of ambition, and presents her desire to destroy the legacy that she'd lost everything to create for him (the fact that she did most of the work in her section of the Argonauts story is lampshaded thoroughly) is treated less as the sinister kind of evil and more the righteous rage of a betrayed demigod whose strained patience at being slowly discarded finally snapped.
- Theseus and Ariadne of Chrete. Ariadne betrayed her father and her people for Theseus and his friends. Theseus and Ariadne fall in love, but Theseus comes up with an interesting way to break it off — leaving Ariadne stranded in an island in the middle of nowhere because of a dream.
Some myths explain that the dream was sent by a god (more exactly, Dionysius the god of wine, theater and fertility), and basically was a "Hands off my woman" message. It may have included a fairly detailed explanation of why one does not want to play the Romantic False Lead to a god. He picked her up after Theseus decided to wisely drop her off; one hopes he told her why instead of just shoving her overboard at the suggested drop site and fleeing.
Also, Theseus soon gets some Laser-Guided Karma for abandoning Ariadne like he did. He had promised to use white sails on his ship to let his beloved father Aegeus know he was alive... he forgot to change his black sails, Egeus saw that and was Driven to Suicide. And not to mention what happened when he got involved with Ariadne's sister Phaedria, too...
- Older Than Steam: Miranda, the daughter of the sorcerer Prospero in William Shakespeare's The Tempest. She fits the trope, except for the betrayal part. Prospero's actually for the match, he just wants to make sure Ferdinand's love-at-first-sight won't end up as out of sight, out of mind.
- Odile from Swan Lake. Daughter of the evil sorcerer, he sent her to seduce the hero.
- Though not quite a mad scientist, Caldwell B. Cladwell's daughter (appropriately named Hope) in Urinetown certainly fits. It is often remarked upon how beautiful she is, she has no idea how cruel her father is, and, of course, falls in love with Bobby Strong. Also a good example of a Daddy's Girl.
- Disgaea 2 features Rozalin, the Evil Overlord Zenon's Beautiful but Spoiled Daughter who's contractually bound — much to her annoyance — to follow the ridiculously impulsive hero on his quest to kick her father's ass. While she starts out as outright murderous, things do start to change when she starts realizing that daddy doesn't seem to want her back safely so much as he wants her out of the way. Then again, he's not actually her father. Or the real Overlord Zenon, for that matter...
- Super Robot Wars:
- Due to the traits of Lemon Browning, Lamia Loveless fits here, as she is the creation of Lemon that eventually got her own conscience and rebels against her creator. She's not the only daughter, however. Lemon also has another daughter and another son (though they did not directly rebel)
- A Mad Dictator's Handsome Son variation exists in Super Robot Wars Destiny, the male protagonist Joshua Radcliff. He did respect his father in a way, but in the same time, he dislikes his father for being too workaholic and bordering a Mad Scientist, because he experimented Rim mercilessly to further his research/job, uncaring that she develops a Split Personality afterwards. And guess what, said father got killed and absorbed into the Big Bad Perfectio and Joshua ends up killing his father to amend his wrongdoings.
- Lune Zoldark, daughter of the original Big Bad Mad Scientist Bian Zoldark, who eventually joins the good guys because she got a crush on one of the heroes, Masaki Andoh. Her defection from her father and falling in love are backwards, (she meets up with the good guys when she's coming back to fight her father, who she thinks has been corrupted by power, and after they've already defeated him), but she's probably one of the best examples.
- Fire Emblem has several:
- Thracia 776 has Sara, who is the adorable-looking granddaughter of the mad priest Manfloy.
- Blazing Blade has both the Handsome Son (though "younger" than most, in a sense) and the Beautiful Daughter. Ninian and Nils are the children of the Big Bad of the game, the Dark Druid Nergal.
- Not to mention another beautiful — okay, cute — daughter in Sonia's (adopted) child, Nino. Sonia is actually one of Nergal's morphs.
- In Fire Emblem Awakening, the Player Character is the runaway son/daughter of the very weird-looking Dragon, Validar. Even when using the older builds for the character (especially the 'older male' one), s/he is always said to be good-looking by the other characters.
- Jade Empire has Silk Fox, the insane emperor's beautiful daughter.
- Mass Effect:
- Liara is the daughter of Matriach Benezia, and it is possible to romance her whether your character is man or woman. Benezia's "madness" isn't her fault, though. It's somewhere between Brainwashed and More Than Mind Control in her case.
- In Mass Effect 2, we discover Tali's father Rael, who performs some ethically questionable experiments on geth, even if he is not evil per se.
- Miranda Lawson is a subversion, since her father clearly intended her to to be this, having created her in a lab from his own DNA to create the perfect daughter and secure his dynasty. Naturally, Miranda had other ideas.
- There's also Alyx Vance, daughter of relatively stable physicist and teleporter scientist Eli Vance. Given that he worked in the Lambda complex and was therefore at least partially responsible for the events which brought the Combine to earth, he probably counts as a little bit mad.
- Next to Doctor Magnusson, Eli is arguably the most sane among the Black Mesa survivors. Alyx's "uncle" and family-friend Isaac Kliener definitely fits the role of Mad Scientist, however; not only does he dabble in experimental and often dangerous technology (such as teleportation and patchwork rockets), he also keeps a defanged, flesh-eating alien parasite for a pet.
- WarioWare has Penny Crygor, Mad Scientist's Beautiful Granddaughter. Of course, she's just as crazy and intelligent as her grandfather, and given the males of the series, is probably grateful for the lack of romance.
- Marta in Tales of Symphonia: Dawn of the New World.
- Nina Cortex from Crash of the Titans, the young niece of longtime series Big Bad, Dr. Neo Cortex. More of a subversion, if anything; She's not exactly 'beautiful', and the reason for betraying Cortex was because she felt he wasn't being evil ENOUGH, and becomes the game's Big Bad. She's still a villain, if somewhat more minor, in her other appearances.
- Keira from Jak and Daxter is the daughter of a mad green eco sage who serves as the main love interest, and serves as the resident Wrench Wench.
- In Overlord, either mistress you run into in the game turns out to be a daughter of the Big Bad (or rather, they are daughters of the wizard who became possessed by the Big Bad).
- In Trauma Team, we have Rosalia Rossellini, Professor Sartre's adopted daughter.
- Pop'n Twin Bee has Dr. Murdock and Madoka.
- Chrono Trigger:
- Schala is a Magitek version of this. Her mother, Queen Zeal, ordered the creation of the Mammon Machine and Black Omen which exploits the power of Lavos which in turn is eating the planet from its core. She succeeds, and become an immortal at the cost of Schala and Janus.
- Lucca and her dad are a Subversion in that both of them are fairly mad (10th century time machine!), but are otherwise decent people and are on your side.
- Scarlet Nova is the daughter of the evil emperor of Gravora in the B-Movie inspired game The Deadly Tower of Monsters.
- Chrono Cross: Kid is Schala's clone/reincarnation/something like that.
- From Pokémon Black and White: N. Let's see: Mad dictator for father? Check. Only son? Check. (If they are related at all...) Beautiful? I think we can let the fangirls field this one. Innocent? His views about the relations between Pokemon and Humans are certainly naive. Late teens? Check. Loves his father dearly? Unfortunately. Kept cloistered from the rest of the world? Oh yeah, to the point where much of Ghetsis' plan revolved around the way this would warp his views! Sometimes has doubts about his methods? He certainly starts to question himself after hearing the PC's Pokemon talk. Falls in love with the hero/heroine? Well...something like that, anyway. At the very least, he comes to see the PC as a friend. Betrays his father? Not until said father has already revealed himself as a monster, so that's a no, but otherwise, N has this trope covered.
- Lady in Devil May Cry 3: Dante's Awakening is eventually revealed to be the daughter of Arkham. She chose to use the name Lady to distance herself from him.
- In Tactics Ogre, we have Mad Necromancer Nybeth, who loves experimenting with the dead. He has three beautiful daughters, two of which rebel against him.
- Resident Evil 6: Sherry Birkin, in addition to She's All Grown Up.
- Borderlands 2 has Angel, the daughter of Handsome Jack who communicates to the player through their ECHO devices initially as part of Jack's scheme to take down Sanctuary but later to help the heroes take down her father (who keeps her around as more or less a supercomputer due to her Siren powers).
- Oblio of video game Dance Central, is the son of the evil mad scientist Dr.Tan, but unlike his father, is beautiful.
- In Mad Father, Aya is one to Dr. Drevis.Of course, this makes her father more eager to make her into a doll, and she becomes a Mad Scientist like her father in the true ending.
- Mortal Kombat has plenty of this:
- Shang Tsung's creations include Mileena (who starts as a Stripperific Butter Face and later switches to Cute Monster Girl), Ermac (Whom are a collection of souls bound into a red ninja) and Skarlet (who is similar to Ermac, but with blood instead of souls) While both Mileena and Skarlet are achingly beautiful (for the most part), Shang Tsung himself bounces between playing straight and subverting this trope as well.
- Quan Chi plays this somewhat straight in X, where the Revenants that he makes are of the dead fighters from ''Mortal Kombat 9, all of which are better looking than he is.
- In the third installment of the Dr. Brain series, "The Lost Mind of Dr. Brain", we are introduced to his assistant, his niece, Elaina, who provides the player with instructions on each mission, as well as hints, if the need arises.
- Ace Attorney:
- Change "scientist" to prosecutor, and "daughter" to "adopted son", and you get Miles Edgeworth, especially if you take into consideration the strong emotional bond (platonic or otherwise) between him and Phoenix.
- Franziska von Karma, Manfred von Karma's actual daughter and while she holds to her father's perfectionist ways she's actually got some moral fiber to her. In the third game she becomes an indispensable ally. Edgeworth needs to be a defense lawyer in Wright's place, but apparently he can't technically do that. After they make sure they get a judge who doesn't know Edgeworth, Franziska comes in to serve as prosecutor because she's the only one who won't rat him out.
- In Apollo Justice, take the Mad Artist's pretty daughter, Vera Misham.
- The superhero Falchion from Does Not Play Well With Others is dating the daughter of his arch-nemesis. Actually, she is his arch-nemesis, who wears a suit of Powered Armor with a voice changer to make her look and sound male, and she exploited this trope for all it's worth to save her own ass when Falchion showed up at her evil lair unannounced while she wasn't wearing the suit. The fact that it also helped her get into his pants was a bonus.
- Girl Genius: Given the backstory, "Mad Scientists rule the world. Badly", it's not surprising that there are a lot of these, played straight, inverted, bent, folded, spindled, or otherwise mutilated:
- Back Story-only: Lucrezia Mongfish, daughter of evil Mad Scientist Lucifer Mongfish, and a Mad Scientist herself. She denounces her father's evil and marries The Hero Mad Scientist Bill Heterodyne. Since Bill, his brother Barry, and all of their True Companions are immortalized in the "Heterodyne stories," she is regarded as a Codifier for this trope in universenote . She turns out to be more evil than her father, and is in fact the Big Bad. Maybe. Her two sisters qualify for this as well. maybe.
- Agatha Heterodyne, Bill and Lucrezia's daughter, the protagonist. Also a Mad Scientist. Agatha's not really innocent, though, being trained as a spark herself. And both her birth and her real parents were firmly good-aligned, so she's not really rebelling. So she's more of a deconstruction of the trope.
- Gilgamesh Wulfenbach, Handsome Son of the Mad Scientist and Anti-Villain (not-so) Evil Overlord Klaus Wulfenbach. Also (say it with me) a Mad Scientist.
- Tarvek Sturmvoraus, Handsome Son of the current (now deceased)leader of a not-so-Ancient Conspiracy. Potential love interest and also (you knew this was coming) a Mad Scientist. He has a sister, who decidedly does not fit the trope.
- The whole thing gets sent up by Othar Tryggvassen, Gentleman Adventurer (and, of course, Mad Scientist): he meets Agatha while imprisoned aboard Klaus's flying airship castle, and, being Genre Savvy, assumes she must be his captor's previously-unknown beautiful daughter, there to either taunt him or set him free.
- Zola, Lucrezia's niece, is at least a mad scientist's beautiful granddaughter. Though unlike just about every other example in this work she doesn't show any sign of having inherited the Spark.
- If Word of God is to be trusted about Zeetha being Baron Wulfenbach's daughter and Gil's twin, then she is an Action Girl but, like Zola, is not actually a Mad Scientist herself.
- Colette, daughter of the Master of Paris, is so far the straightest yet iteration of this trope, being the beautiful daughter of a (take a shot) Mad Scientist, who helps out the heroes - but not in defiance of her father, because the Master of Paris is on the good guys' side, just rather stern. Colette ends up ascending to the role of Master of Paris upon her father's death, while finally breaking through to become a Mad Scientist in her own right.
- Michelle Flammel from Monsterful, her father Lionel Flammel is a handsome Mad Scientist/alchemist/magician known for his mad creations. Michelle loves her father dearly but she also thinks that he can be very stupid at times.
- This is expanded in the ongoing Narbonic fanstory The Mad Scientist Wars, where Jane Narbon is the (incredibly beautiful) daughter of Helen Beta and Dave. In addition to being The Vamp, she's also (yup) Mad.
- Helen Beta Narbon, the main character of Narbonic, who is actually a clone of her mother (and comes from a long line of clones) and a mad scientist herself.
- Hannelore from Questionable Content. Raised on a space station by a Mad Scientist and a Corrupt Corporate Executive. She rebels, but doesn't betray either of them. Also, she was less "cloistered away" and more "neurotic to the point she wouldn't talk to anyone except the station's AI".
- Her name is Conquest (Connie for short), and the phrase Anything That Moves hardly does her justice. She is known for giving out sex "free with purchase", any purchase, at her father Galasso's toy store. Nevertheless, he seems to be under the impression that she is a virgin, even though he has continually forced her to copulate with anyone he considers capable of producing a (male) heir for him. There's even mention of a time he witnessed a heroic horse, and tried to use her to breed centaurs. Despite having a head full of air and a libido that's Up to 11, she is surprisingly canny and eventually rebelled against her tyranical father, and is now apparently one of his main business rivals. She's still a tramp, though, and considers a tryst with one of Galasso's more attractive male employees a suitable substitute for a briefcase full of cash as a bribe.
- She's also a direct parody of Talia al Ghul (see above). Galasso decided to name Ethan his successor, and gave him Conquest as part of the deal. He went for it at the time, but later discovered that he is gay and refused to go through with it any more. Galasso didn't even seem to understand the concept, and then ordered Robin to impregnate Connie instead. For the record, Robin is a girl. Yeah, the jury's still out on how someone like Galasso managed to acquire a daughter to begin with.
- Oasis was one of these to Dr. Steve during her first appearance in Sluggy Freelance. Interestingly, Steve actually uses his mind control device to make Oasis fall in love with Torg, much to Torg's displeasure.
- Tabitha in Far Out There is not only a looker, but followed her Daddy's footsteps into being a Mad Scientist herself.
- Jadis Diabolik of the Whateley Universe, in her first (chronological) appearance, even references this trope. It's one of her hot buttons that she's the daughter of the infamous mass murderer Dr. Diabolik, and she has the Exemplar superpower, but she's isn't actually beautiful - she's plain, and elsewhere would be considered moderately attractive, but compared to all the other Exemplars running around, she feels incredibly ugly (plus, it hasn't been stated for certain that she is an Exemplar or if something her father did just mimics the effects). She is particularly sensitive about not having the Most Common Superpower, which is almost universal in female Exemplars (at lest those who don't get a Body Horror result instead). Despite this, she did have a guy vying for her attention after she saved him from a smalltime super villain thug, and two others at Whateley (though one's a creep who imagines himself to a Batman-esque Byronic Hero, and the other just wants favours from her father and the parents of the other Bad Seeds).
- Gaia Online's Gino Gambino might be a dude, but he otherwise fits this trope.
- Doctor Gladiola Thanos, a Diabolical Mastermind from the Global Guardians PBEM Universe is the daughter of Mad Scientist Doctor Thaddeus Thanos. Her father was active in the 1980s and regularly fought the heroic Captain Challenger until he was killed during a lab explosion that resulted from a fight between the hero and Doctor Thanos's minions. While she originally followed this trope by helping the hero fight against her father's diabolical plots, his death sent her into a Heroic B.S.O.D. that ended with her following in his footsteps as a supervillain. Her first act of villainy was to find and kill Captain Challenger and his entire family.
- An unofficial Champions character named The Scientist has a young, beautiful, virgin daughter. And he always calls her that, much to her chagrin, until her kidnappers (the evil M.A.C.R.O.N.) return her and say "Here you are, your young, beautiful ... daughter." ("It was my idea, daddy. Have you seen what this hunk looks like under his armor?!")
- Dr. Havoc's Diary: We have Ally Havoc, the daughter of the titular Dr. Darren Havoc.
- Though a departure from her portrayal in the comics, Lorna Dane a.k.a. Polaris is made into something of a Mad Scientist's beautiful daughter in Wolverine and the X-Men. She, unlike her siblings, is intentionally kept innocent and naive of the reality of the society her father (Magneto) created on Genosha. And in one episode she falls for Gambit who, while his status as a hero may be suspect, is the enemy of her father (in that he plans to steal from him.)
- Aelita from Code Lyoko, though her father's sanity is more questionable than definitely not present.
- Bonnie Lepton in the Buzz Lightyear of Star Command episode "Eye of the Tempest", the All Grown Up daughter of a former Star Command scientist who became mad after experimenting on himself.
- Jimmy Neutron's nemesis, Professor Calamitous, has a daughter who's actually named "Beautiful Gorgeous". Contrary to the trope, she's possibly more evil than her father, and almost certainly more effective at it.
- My Life as a Teenage Robot:
- Melody is a mad scientist's beautiful robot "daughter"... unbeknownst to her love interest Brad as he struggles to escape from her father's captivity.
- Jenny herself, though it was her mother who made her. At first, she was only allowed out to save the world.
- Phineas and Ferb:
- Vanessa Doofenshmirtz (pictured) plays with this trope in different ways. In early episodes she was outright disdainful towards her father and his experiments, generally playing the role of Deadpan Snarker. She warmed up to him in later episodes, though she remains somewhat annoyed by his exploits and his attempts to make her into a Daddy's Little Villain (though some of her actions hint she may head down that path anyway). She's also notably uncloistered (she only spends alternate weekends with her father anyway) and keeps her relationship with his nemesis friendly but strictly platonic.
- Played Straighter in recent episodes, when she has developed an interest in Major Monogram's son, (human) secret agent Monty Monogram. However, their first date actually devolved into a fight when Monty made a comment about her father, so the betrayal part probably isn't going to happen.
- Ultimately, in the final episode Vanessa convinces her father that he never really wanted to be evil, and that he just felt like his Hilariously Abusive Childhood obligated him to become a mad scientist. Hence his status as a Card-Carrying Villain who gets uncomfortable whenever other villains do something really evil, or when one of his plots unexpectedly succeeds. Cue Heel–Face Turn.
- Kitten from Teen Titans may not even truly have been human, seeing as her father was Killer Moth, and her beauty was clearly only skin deep but given the nature of Killer Moth's scheme's she technically qualifies.
- Subverted in the short-lived MTV cartoon Spy Groove with Sierra Nevada, the daughter of a mad robotics genius/casino owner. Turned out she was the mad genius; daddy was just a robot she built to draw attention away from her while she played this trope to the hilt to fool do-gooders.
- The second season of Jonny Quest: The Real Adventures not only brought back the Quests' arch-nemesis Dr. Zin, it also gave him two daughters, Anaya and Melana, one whom becomes romantically involved with Hadji.
- Though not necessarily a bad guy, Dr. Orpheus from The Venture Bros. is a mad scientist/necromancer with a relatively normal teenage daughter, Triana, whom he loves and cares for, humorously mixing his medieval, renaissance faire-like attitude with the trials of a modern-day single dad.
- In Danny Phantom, Jazz defiantly takes after her mother. Even when she won't admit it and when Jack Fenton is more bumbling than mad.
- In The Legend of Korra Asami Sato is a case where she didn't know she was the daughter of a mad scientist who hid behind the image of a successful business owner that secretly supplies weapons and Mini-Mecha to the Equalists. Even if her father had a strong Freudian Excuse for doing so, she is not happy to discover this.
- And the leader of the Equalists, Amon/Noatak, was the Tall, Dark, and Handsome son of would-be mad dictador Yakone. Same goes to his younger brother, Tarrlok.
- Farmer Brown from the Batman: The Animated Series episode "Critters" can count as a Mad Scientist, seeing as he was using microbiology to create monstrous farm animals. And he did indeed have a beautiful daughter named Emmylou. She was also his enforcer, and was much stronger than her almost petite frame would appear, being more than a match for Batgirl. (She claimed it was due to beef steroids, clearly another of her dad's experiments.)
- In Skysurfer Strike Force, Cerina is the daughter to show Big Bad, Cybron. Unlike most of the examples though, she's clearly evil.
- Julie Kane in Motorcity. Abraham Kane's technically not a mad scientist, but she still fits the trope. She also kept it a secret, fearing her friends will think she's just like him.
- Dr. Vahtoss and his daughter Carmalita from The Tick.
- The Ben 10 series invokes this with Attea, daughter of Emperor Milleous. Her father has her carefully watched, but she manages to betray him, fall for the hero (when he's the same species), and take over daddy's empire over the course of a two-parter.
- In Rick and Morty, Beth (the daughter of Rick and mother of Morty) is older than the typical example, but still qualifies. Much like Rick, she's smart, selfish, and an alcoholic, albeit to a lesser extent. She slips into the typical Daddy's Girl, often giving Rick the benefit of the doubt and putting him ahead of other family members, but isn't above calling him out when his antics are particularly egregious.
- Catherine Barton was the niece of Isaac Newton (he never married and had no children), but she did live in his house in London. She was renowned for her beauty and wit. Newton himself was an Alchemist and heavily into the occult and weird.