Lemon Wacky Hello - Television Tropes & Idioms

Drink cactus juice! It'll quench ya! Nothing's quenchier! It's the quenchiest!

Topher Brink: You know what I like? Brown Sauce? What's it made of? Science doesn't know!
Adelle DeWitt: It's made of brown.
Topher Brink: Brown...mined from the earth by the hard scrabble brown miners of north Brownderton!
Adelle DeWitt: Oh my god, I find lentils completely incomprehensible.
— "Echoes," Dollhouse

One or more characters accidentally partakes of some behavior-altering substance. There are several ways this can happen:

Characters consume a tasty treat which, unbeknownst to them, is laced with drugs.
Characters unintentionally take more than the recommended dose of painkillers or some other prescription drug.
Characters experience mind-altering side effects from overconsuming a completely innocuous substance, like sugar, ice cream, or steak sauce.

However it happens, they wind up behaving in a very loopy manner.

This type of one-shot drug (no pun intended) use is far more likely to cause Hilarity than to be used in the service of a Drugs Are Bad aesop. If there's a Will They Or Won't They situation already established between two characters, the writers may be tempted to bring in Kissing Under The Influence.

See also I Can't Believe It's Not Heroin. If the substance in question goes beyond altering behavior and causes the characters to hallucinate, it's a Mushroom Samba. If the character passes out immediately afterwards, it's a Non Sequitur Thud. Sometimes the Lemon Wacky Hello is caused by a G Rated Drug.

Examples

Anime and Manga

In the manga & anime of Ah My Goddess, Belldandy gets drunk on cola, and proceeds to wander around town granting wishes.
This happens to Usagi twice in Sailor Moon, in both cases she mixes up alcohol with juice. First in the first season in an episode based directly on a manga chapter she winds up Kissing Under The Influence (bad Mamoru!); and a second time in the third (S) where it's actually much funnier. In the second case she goes completely la-la and starts speaking gibberish in both Japanese and English at swanky party, the (English) guests find her delightful.
Usagi: (butting into a discussion on the theory of relativity) The pudding of relativity? Let's see... Well, in other words, you take milk, eggs and sugar, and stir it all up. Then you put a lid on it, and for about 30 minutes, you steam it... Oh! And if you forget the whipped cream, you're no good as a woman. Yeah.
- What's even more hilarious about these incidents is that Usagi normaly takes no more than a couple of sips of the drink in question. Either that's some strong wine they're having or she's an utter lightweight.
- The dub sadly changes this as much as possible into her getting sick from drinking to much juice.
At the beginning of The Tyrant Falls In Love, Souichi unknowingly drinks a bottle of alcohol that's actually a powerful aphrodisiac. It doesn't change his personality (which is as bad-tempered as ever), but it does make him painfully turned on and severely immobilized to the point where he's unable to relieve it by himself. Morinaga, who's wanted him for years, decides to help him in a way that goes far beyond Kissing Under The Influence. What happens in the morning after the drug wears off is not a pretty sight.
Admiral Leti of Magical Girl Lyrical Nanoha downs one bottle of Earth wine in the last Sound Stage of the second season during the Hanami Festival. Then she downs another. Then another. Then she starts screaming out for Hayate's knights using their "Wolkenritter" name while in front of some Muggles and generally making a spectacle of herself until Lindy and Fate leads her away before she blows the Masquerade wide open.
In Hidamari Sketch, Hiro wrongly bought alcoholic juice at Yuno and Miyako's welcoming party, and the two freshmen got drunk. While Miyako is still herself, the generally innocent Yuno started ranting about It Just Bugs Me's... and Sae uttering an Engaging Conversation even she was not drunk...
Rock Lee's sake induced drunken kung fu in Naruto.
In Clannad ~After Story~, after drinking one cup of sake, Nagisa immediately starts acting like a Clingy Jealous Girl towards Tomoya... in regards to her mother. Then said mother gets drunk too, and starts acting flirtatiously towards Tomoya. Needless to say, Tomoya was not very happy about this situaton.
In OnePiece Luffy eats a bit of a cactus whilst trekking the desert of Alabasta in an attempt to quench thirst. Hilarity ensued.
In the first Dragonball Z Deadzone movie, Gohan eats a delicious looking apple from Garlic Jr.'s personal orchard. Turns out that "Children mustn't eat those". Cue the drug trip montage.
Seto No Hanayome has all the female cast and Saru drinking Uoihatsu, a mermaid drink that makes a person "act on their instincts". This leads to a group of drunken junior high schoolers running around a movie set, and hilarity ensues.
Cardcaptor Sakura featured an Omake in which Kero Beros and Spinel Sun fight over and chase the last takoyaki given to them all across town. At one point, Spinel Sun plows face-first into a cake, giving him the Lemon Wacky Hello, complete with a dazed hiccup and crazy mouth lasers of all things.
Genshiken has a "New Member Party" in the first season, where one potential member gets soused and wanders the resturant signing the theme song from ''Kujibiki Unbalance'' loudly. Granted, his character type is one that may do things like that anyway, regardless of alchohol consumption or public exposure.

Comic Books

In comics, one adventure Superman had resulted in acting in a very... festive◊ manner.
- Another (also featuring kryptonite) had him seeing every member of the Justice League in overly-cartoony chibi-style, using heat vision on the TV when he sucks at video games, and getting a severe case of the munchies.
  Superman: Oh man, I smell brownies! You guys smell brownies cooking? *Runs to the window and looks out across the vast gulf of space between the Watchtower and Earth* Oh man, someone's making brownies in North Dakota! Oh my god, we totally have to go to North Dakota, they have brownies!
  - This troper would like to suggest a petition to make that last phrase North Dakota's motto.
  - This troper seconds the notion.
  - This troper wants to know why that isn't already North Dakota's motto.
  - Win.
  - This troper would like to point out he recently bought a "Let's go to North Dakota. They have Brownies." T-Shirt, so I suppose this is half the battle.
  - Edit: This troper found the strip after googling it and laughed HARDER
  - here is a LJ post of the comic
In Jeff Smith's Bone, Thorn and Fone Bone get tipsy from hiding in the woods and eating nothing but berries.
- The berries could have fermented. This happens, and birds get drunk from the juice and fly into things. Hilarity Ensues

Fan Fiction

In Harry Potter fanfic The Well of Shadows Professors Hillary and Gregory Proteus, who are Harry and Ginny's future selves do this to Severus Snape. The first we hear about this is when Snape greets his class with a bright "Good mornin' all you happy people!". Hilarity and disbelief ensue.
In Chapter 13 of Daniel Jess Gibson's megacrossover fanfiction ''Sic Semper Morituri,'' one character, while recovering from emergency surgery and loopy from drugs, grabs another character and kisses him on the mouth, in front of his girlfriend, no less. The reader may find this to be welcome comic relief after some rather horrific events. Or not.
A Yu Yu Hakusho fanfic Purple High is entirely this, when Kurama attempted to breed a Makai plant capable of curing burn wounds, and instead creates a powerful hallucinogen that, among other things, prompts Kurama to reveal his stash of green spandex, gives Hiei the munchies, compels Botan to prostrate herself before Kurama to learn his hair-care techniques, and turns Yukina into an Ax Crazy, Cloud Cuckoo Lander Card Carrying Villain.

Film

Alan Tudyk's character in Death At A Funeral. A strait-laced businessman takes what he thinks is an anti-anxiety pill, and spends the rest of the movie making funny faces and stripping. At, as the title suggests, a funeral.
Joe Dirt: Joe gets the idea to ask a police sketch artist to make a portrait of his missing parents. He raises the money, but... "Somethin' happened to my head. See, I spent the night in what I thought was an abandoned circus tent... I guess there was no circus." Cue the gibberish singing and crazy nudity as Joe is whacked out on bug bombs. Needless to say, this throws off the sketch artist considerably.
In Dick, the two air-headed female leads, who are working as White House interns during the Nixon administration, use their older brother's "secret ingredient" - which they don't realize is marijuana - when making brownies. Nixon loves the brownies and serves them during an important meeting with officials from the Soviet Union. (It goes rather well.)
- Not just officials — his famous summit with Russian Premier Leonid Brezhnev is a success thanks to this trope.
Lover Come Back
Subverted in Euro Trip, sort of. The characters eat brownies at a Jamaican-like shop in Amsterdam, which they believe to be laced with marijuana - but in fact aren't. This doesn't stop them from acting all loopy until the owners point out that they're completely drug-free. (Then there's the time when the brother and sister make out after taking Absinthe for the first time...)
In Bad Boys II, Marcus accidentally ingests LSD, and starts acting weirdly - just as he and Mike get to their boss' house to report progresses in investigation...
I love you Alice B. Toklas: She had a freaky cookbook.
Blind Date Kim Basinger's character is allergic to alcohol (with predictable results when she imbibes). Bruce Willis injects a box of chocolates with brandy in order to sabotage her wedding to John Larroquette's Jerkass.
In Juno, the titular character tells a classmate about a girl who overdosed on psych meds, stripped naked and dove into a mall fountain shouting "I'm a kraken from the sea!". Said girl turns out to be Juno herself.
In the movie Saving Grace the two old ladies who run the village store are told that a marijuana plant is an exotic tea. They steal a few leaves and brew them up so they can taste this new tea. They proceed to get stoned much to the bewilderment of their customers.
- Which is a case of Did Not Do The Research; THC is not water soluble, so a cannabis tea would have virtually no psychoactive properties unless some a fatty component was added.
Harry Potter on Felix Felicis - probably the funniest moment of the entire movie.
The Hangover starts out this way. The majority of the movie is the protagonists trying to unravel the resulting Noodle Incident.
In Never Been Kissed, Drew Barrymore's character eats a brownie at a dance club. The man who gave it to her said it was rich in "Vitamins T, H, & C!". She ends up passing out, and her hand-stamp ends up writing "loser" on her head.
In Flirting With Disaster, Ben Stiller's character finally meets his birth parents, old hippies who manufacture LSD. His newly-acquainted resentful brother doses his dinner with the stuff, but it gets eaten by a Federal agent who is along for the trip (as it were).
In Charlie Chaplin's short film "The Cure," the protagonist has gone to a health spring resort to cure himself of alcoholism. The management finds his secret stash of alcohol and gets rid of it . . . by throwing it out the window, and right into the health spring. A wild party ensues.
- In Chaplin's Modern Times, he mistakes cocaine for salt and ingests a generous dose. In the ensuing frenzy he ends up foiling a prison break and is hailed as a hero.

Literature

A Running Gag throughout The Areas Of My Expertise is "getting either very high or very autistic".
I Claudius has a rare serious version where after Claudius finds out that his wife Messalina has been cuckolding him (something everyone else in Rome has known for years) and that she is on the verge of having him overthrown, his evil but loyal chancellor gives him some drug which is supposed to calm his nerves. While on the substance, Claudius experiences delusions of grandeur and is able to calmly sign the death warrants of Messalina and the other 500 people at a party she held when plotting treason, something he would have been too kindly to do with a clear head.
Neil Gaiman's Neverwhere has a scene where Richard and Door drink some wine from Atlantis: apparently, when wine ages, it gets more potent. Richard gets tipsy on the way out and wonders if Door wants him to kiss her. Thankfully, he doesn't go for it.
In Anne Of Green Gables, the titular character accidentally gets her best friend drunk at a tea party when she serves currant wine instead of the less-potent raspberry cordial she meant to bring out.
In HG Wells' First Men in the Moon, eating the lunar flora has this effect. The conversation is truly ludicrous.
Max on Valium, from Maximum Ride. She has to get drugged up to get rid of the chip in her arm. Hilarity Ensues.
"I love you! I love you sooo much!!!"

Live Action TV

The Trope Namer is an episode of Just Shoot Me in which all the characters try a dirt-flavored Chinese treat which turns out to be a potent drug. (Personal note: this is one of the funniest episodes of television, ever.) Another episode had Maya accidentally get high off of Nina's nicotine patch when she mistakes it for a Band-Aid.
- Another had the office being bombed for bugs while Nina was still inside, causing the letter she was writing in voice over to descend into gibberish.
Seinfeld, Elaine takes too many pain pills, laughs at everything, yells "Stella!" a lot.
Friends, Ross takes too many pain pills, accuses Chandler of being gay, declares his love for Rachel, passes out. On Rachel.
- Ross has a sugar rush - twice - on a later episode.
Frasier, Martin unwittingly eats a hash brownie, devises a vague notion of a dog army.
- Hilariously, this is because Niles wanted to get high and thinks he succeeds, his hash brownie being switched with his dad's.
That 70s Show, the parents accidentally eat Hyde's special brownies and share one of those drug-addled Round Table Shots their kids usually indulge in.
- Another episode of That 70s Show had Donna order a few iced teas while at dinner with Eric. The waiters brought her Long Island iced teas. Donna tried to drag Eric under the table for a "private rendezvous."
Coupling, Jane takes a couple of mystery tablets, reinvents herself as a children's entertainer, creates a sock puppet who insults everybody including her.
Jane: I'm not self-centred.
Jake the Snake: You're arguing with yourself!
Jane: Well, so are you!
I Love Lucy, Lucy does a commercial for 80-proof health tonic Vitameatavegamin, but keeps having to do extra takes, swigging the stuff each time. This results in her becoming drunk and making increasingly comedic bloopers. Possibly the first example of the trope.
The Drew Carey Show, an experimental sex drug from DrugCo is dropped in the Buzz Beer tank the day Drew has to go to court.
A rare dramatic example: in The Dead Zone, Johnny accidentally inhales a massive dose of ketamine, which renders his normally literal visions bizarre and cryptic.
On an episode of Barney Miller, Wojo's girlfriend bakes him brownies which he brings to the station. Of course, they're hash brownies, leading the characters to utter such lines as "Let's go down to the docks and shoot some clams," and "Has anyone seen my legs? They're about this long."
Brennan and Angela inadvertently ingest crystal meth at a club in an episode of Bones. Their goofiness is short-lived, but does result in an exchange that sums up the trope:
Booth: Are you two high?
Angela: Yes, but only accidentally, so it doesn't count.
- In the Christmas episode of the same show and season, the team gets given an antidote for a fungus they might have inhaled. Booth has a bad reaction and pretty much gets high. What makes it even better is he starts doing this after a laundry list of side effects are read off to them, including vomiting and skin rashes, making Hodgens proclaim,
  "That is so not fair."
- Also, when Booth hurts his back in "The Princess and the Pear," vicoden "makes the furniture feel friendly"
President Bartlet on The West Wing complains in a first-season episode that his back medication makes him loopy...and is proven right, as when on the painkillers (two different kinds) at the end of the episode, he spaces out, confuses the names of his staff, and announces — with all the gravitas of the President of the United States — that he's been seriously thinking about getting a dog.
- Frighteningly close to the reality of the Kennedy administration. JFK spent much of his Presidency stoned on painkillers for a back injury, which led to serious issues in how Khrushchev perceived him, and is theorized as an indirect cause of the Cuban Missile Crisis.
- Likewise Anthony Eden was using Benzedrine (then regarded as a harmless stimulent) which likely contributed to his poor handling of the Suez Crisis.
In Malcolm In The Middle, Lois refuses to take her painkillers on the grounds that they make her 'loopy'. Reese spikes her milk with them. There follows an odd, disjointed conversation with the high, giggly, mellow Lois and her husband, who hasn't even noticed.
In the Three's Company episode "Up in the Air", Jack unintentionally mixes tranquilizers and alcohol and winds up dancing with a planter on his head.
- It was a plant in a pot, not a planter (and not observably pot either). Er, Or So I Heard.
On one episode of WWE Smackdown!, John Bradshaw Layfield accidentally shot himself with a tranquilizer dart he had intended to use on The Big Show. While high on tranquilizers, he came out to the ring in a jacket, tie, and boxer shorts, and cut an extremely surreal promo, in which he beat up an inflatable dinosaur, claiming it was Godzilla, and commented repeatedly that The Big Show "eats pizza".
- This troper was rather entertained by JBL during this segment—the first and possibly only time I was amused by his antics during his title run, actually...
Spike, in his first appearance in Buffy The Vampire Slayer, recounts an incident where he "fed off a flower person" at Woodstock. ("...and I spent the next four hours watching my hand move.") Vampires in the Buffyverse are especially susceptible to unwittingly taking drugs by drinking the blood of users, and one episode depicts a designer drug meant to be shared by a human and a vampire.
In a darker inversion, a lonely movie star on season one of Angel gives Angel a happiness inducing drug without him realizing it. What she doesn't know is that she doesn't want Angel to get happy, as he (this time temporarily) turns evil and tries to kill her.
The first episode of Walking With Beasts has some proto-horses getting drunk off fermented berries. Their reflexes are so dulled by this that one of them gets eaten by a whale.
In an episode of the Naked Brothers Band, Nat acts like this after going to the dentist.
In an episode of Taxi most of the cast gets baked out of their skulls eating Latka's (unintentionally) cocaine-laced cookies.
Jim: They're coca leaves . . . [chew-chew] . . . from Peru . . . [chew-chew] . . . southern Peru . . . [chew-chew] . . . before the rains . . .
- In the episode "Reverend Jim: A Space Odyssey", Jim slips a tranquilizer (not a Chiclet) into Louie's coffee while the others are trying to figure out how to get him a job at the taxi company. It takes effect almost immediately, causing him to act significantly nicer than he usually is, start singing, pass out on one of the taxis, and agree to giving Jim a job when Bobby asks him.
In the Firefly episode "The Train Job", Simon drugs the mercenary Jayne to keep him from causing trouble while waiting to The Captain Mal to get back. Jayne manages to get to the cockpit/bridge and yell at Wash for a bit before the drugs take effect and he passes out.
Jayne: Now we're finishing this deal, and then maybe, maybe we'll come back for those morons... got themselves caught... and you can't change that by getting all... bendy.
Wash: All what?
Jayne: You got the light... from the console to keep you... lifting you up... they shine like... [starts grabbing at the air] little angels...
[Jayne promptly falls flat onto the floor.]
Wash: Did he just go crazy and fall asleep?
- Simon did tell Jayne to sit down...
The My Name Is Earl episode "Robbed a Stoner Blind"? Randy ends up eating some "herbs" intended for his head wound and we end up viewing most of the episode via Randy's eyes in Claymation form.
Six Feet Under. David stashes the E tablets his boyfriend gave him in an aspirin bottle in the family kitchen. Nate decides to start taking an aspirin a day. The two events coincide the evening of a family dinner party. (See also Mushroom Samba for other repercussions of the E-filled aspirin bottle.)
In an episode of Spaced, Simon Pegg's character ingested a lot of "bad speed" before the episode begins. He spends the rest of the episode just barely in his mind before crashing, while at the same time delivering wonderful insights to his friends inadvertently and fantasizing about killing zombies after a drug-laced session of Resident Evil 2.
A variant from an episode of Perfect Strangers: suffering from a terrible cold on the eve of a big date, with all other options exhausted, cousin Larry agrees to take "the Mypos Cure." Balki mixes up a batch of the awful potion for Larry, who forces himself to gulp it down when Balki leaves the room... returning with a tiny spoon, the intended dosage for a single person. Larry passes out and awakens several days later - hey, but at least his cold is gone!
Stephen Colbert marked the demise of (father of LSD) Albert Hoffman when his interns made him a sheet of little stamps. He decides to pre-lick the entire sheet right away. The results start at Contemplating Your Hands and go all the way to an epic fourth-wall-breaking freakout over whether he's a real person and why he does the things he does. He ends the show in his set's "fireplace" (a set piece looking like a brick fireplace with a flat-screen TV showing a burning fireplace fire) and claims that the fire looks fake.
- He had a similar reaction when he briefly ran out of the prescription painkillers he'd become addicted to.
  "You have your math but he has the math. I see numbers! And five is very angry. Come back, five!"
Thats My Bush - After a drug bust, the President takes three hits of ecstasy, which were indistinguishable from run-of-the-mill aspirin.
The Black Books episode "The Blackout" has Manny consuming too many espressos while watching cop shows, leading him to chase a purse snatcher, be mistaken for a plainclothes policeman, and sit in on an interrogation (and nab a confession through his unconventional Good Cop Bad Cop performance).
- Another episode, "The Big Lock-Out" has Manny trapped in the bookstore with nothing but a bottle of Absinthe, which he drinks and in the ensuing dementia roasts and eats the bees he finds on the windowsill.
- In the first episode, Manny, as well as excessive amounts of espresso, accidentally swallows The Little Book of Calm, making him into a sort of stoned, platitude-spouting, Zen... thing.
In one episode of House, House slips a little something in Wilson's coffee...
Wilson: I'm not on antidepressants, I'm on speeeeeeeeeed!
In an episode of MST 3 K, Crow creates a Gargle Blaster called a "Killer Shrew" out of about a dozen different sugary substances. A single sip sends TV's Frank on a hyperglycemic bender as he races around the lab jabbering madly, then passes out.
Appears in the "Who can keep a dead Octopus on their head the longest?" episode of Kenny Vs Spenny, only enhancing the weirdness already present in the challenge.
In the episode of Arrested Development called "Afternoon Delight", Michael asks Oscar to give Lucille some "afternoon delight" so she wouldn't be stressed out. While the delight in question is sex, Oscar thinks he talks about marijuana, and gives her some marijuana-laced brownies. Later, completely stoned, she drives to Balboa Island in her car, runs over Tobias without realizing it, and crashes the car into the Frozen Banana stand.
In Dollhouse, episode 7 - "Echoes" - a hallucinogen that is transmitted by touch wreaks havoc on the dignities of several Dollhouse security guys as well as Ms. Dewitt and Topher.
The Knights of Prosperity didn't last long, but lasted long enough to follow this trope. One episode had the Knights getting stuck in a panic room. Esperanza, who's claustrophobic, takes some medication and subsequently becomes very loopy. Louis observes "I think she took more than the recommended dosage."
Night Court also used the "I ordered an iced tea but they brought me a Long Island Iced Tea by mistake" routine with Christine. (You'd think people would notice the difference in taste ...)
- Considering that a Long Island Iced Tea, if properly made, is meant to taste EXACTLY LIKE ICED TEA, this is not so strange.
On How I Met Your Mother Ted is dared into doing five shots of an unnamed alcoholic drink. He's convinced that, as someone with a "super-brain," he's immune to doing anything stupid. He is wrong.
"How easy do you think it would be to sneak into the zoo? I have to see some penguins, like, right now."
"Go into my stable and take my finest stallion. He's yours! His name is Windjammer!"
My Family had a joint that actually turned out to be made of cinnamon and oregano powered by the placebo effect shared by Ben and Susan. Effects range from Susan overcoming her habitual mental block as to how horrible her cooking is, Ben correcting the lyrics to Jimi Hendrix songs at the top of his voice, and the immortal phrase (on an egg-smashing demonstration of This Is Your Brain On Drugs) "She's killed our brain!"
In an episode of Taxi, Alex is given some uppers and told that they are a headache remedy. He is then summoned to see the boss to explain a minor accident he had been involved in earlier while talking a million miles an hour.
Dead Like Me, "Reapercussions." Mason starts smuggling drugs as a mule to raise cash... but the balloon breaks. Since he's a reaper, the overdose won't kill him, but he still spends most of the rest of the episode complaining about how he can't feel his arms, freaking out, and talking about The Crying Game.
In one episode of MidsomerMurders, Barnaby is offered cookies by a charming elderly couple. He then spends the rest of the day acting quite loopy, laughing and giggling. (Note: Barnaby laughing is among the most terrifying scenes in existence.) Later on, it turns out the elderly couple grew marijuana in their backyard, and everyone (but Barnaby) knew about it but thought he let it slide.
In an episode of The Closer, Brenda's niece, visiting for a few weeks as a "straighten up and fly right" experiment on the part of her parents, receives a "package" from a friend back home, which she bakes into brownies. When Brenda comes back, her impeccable nose for all things sweet conspires with her sweet tooth to lead her to the brownies in the niece's room. Brenda eats three, and while she appears to have a wonderful time, her husband Fritz was not amused when he returned.
- Brenda won't be either if she gets picked for random screening before they completely depart her system.
In a third-season episode of Kingdom, the title character eats a omelet containing some special mushrooms.
Carlton experiences this in an episode of The Fresh Prince Of Bel Air. He consumes a handful of Will's uppers at a high school dance after mistaking them for vitamin E pills, causing him to go wild and steal the dance floor in a scene strangely echoing an infamous episode of Saved By The Bell.
Drop The Dead Donkey. Damien gets high while reporting on soldiers burning a huge pile of confiscated marijuania.
One of the best examples happened in the Australian show Frontline, in the episode "My Generation". Mike, the host, has a headache, and when Shelley the receptionist looks for some Panadol for him, she finds the heroin tablets Marty confiscated from one of the camera dudes. The ending is hilarious.

Video Games

Not sure if this belongs under Mushroom Samba or not, but any MGS fan worth thier salt knows that if you have Naked Snake eat certain glowing mushrooms in Snake Eater, he'll have a very interesting conversation with Para-Medic about how his batteries recharged.

Web Animation

Homestar Runner: In the Strong Bad e-mail "caffeine", Strong Bad slips some instant coffee into his younger brother Strong Sad's orange juice. Hilarity Ensues (for real) as the caffeine turns Strong Sad into a hyperactive talkative loon.
- The real kicker? Strong Bad referred to the substance in his younger brother's juice as Sanka. Strong Sad was somehow buzzing on decaffeinated coffee. Which, admittedly, does have trace amounts of caffeine in it, and Strong Bad did say he added "several heaping spoonfuls" of the stuff.
- Additionally, Strong Bad and the Cheat both drink straight soy sauce with hilarious results in one episode. Strong bad attempts to fly Bub's Concession Stand to the moon, while the Cheat tries his best to eat it.
- In another email Strong Bad starts acting stranger than usual, and Strong Sad asks if he took "some of my pills again", suggesting that this sort of thing is a regular occurrence.

Webcomics

In the sequence from Unshelved where Dewey had mixed his muscle relaxants with his painkillers.
In Shortpacked!, Robin De Santo (who already has a superhuman hyperfast metabolism) ate Cadbury Eggs as a breakfast cereal and when she came down, she had been elected to the U.S. House of Representatives on a platform of getting a Padme Amidala doll produced and flashing her rack. She has no clear memories of doing this.
In this strip of Questionable Content, a change in Hannelore's anti-anxiety medication (for her OCD) causes her to get all the way to the coffee shop without realizing that she was still in her underwear.
- This strip lets us see what's making Tai so giggly while she's singing LSD's praises. "When you use big words, smoke comes out your nostrils!"
In Gunnerkrigg Court, Antimony and Kat eat enough cherries to stain their hands and clothes red. They get tipsy, and the opposite of hilarity ensues.

Western Animation

Meatwad of Aqua Teen Hunger Force once had an episode like this, wherein he ingested some expired "cheese" that made him believe he could predict the future whenever he touched people. He began predicting disasters that turned out to be minor annoyances, such as milk going bad or the garbage stinking. In the end, it was revealed that the "cheese" he ate was actually caulk, and a listed side effect of its ingestion is "making you think you can see the future but you can't".
In Daria, Jake picks several unfamiliar berries while the family is out camping, which all but Daria eat. Soon, Jake and Helen are chasing after his spirit animal', while Quinn tries to use a mudpuddle as makeup; in the end, Daria has to call for them to be airlifted to a hospital.
Futurama:
- Lrr, Emperor of Omicron Persei 8, eats a hippy right before delivering a speech in "The Problem with Popplers", and ends up rambling about his hands.
  "Urg...I thinking something some was wrong with that hippie. CITIZENS OF EARTH I WOULD LIKE TO tell you...that my hands. They're sooo big. They can touch anything but themselves... (touches them together) whoa."
  - This Troper's mother absolutely loves this scene.
- Dr. Zoidberg is injected with painkillers in "Bender Gets Made": "Why always with the fighting?"
  Clack... clack.
  - And then minutes later: "Oh God, I'M COMING DOWN!!"
- The essence of pure flavor is nothing more than water. Water laced with LSD.
An episode of Dexters Laboratory has him and Dee-Dee try coffee to see what all the fuss is about. They end up consuming all the coffee in the house and going on a hyperactive bender. Meanwhile their parents learn that they are out of coffee and go through the effects of withdrawal.
Happens in Beavis And Butthead. Whenever the eponymous Beavis consumes too much sugar - which doesn't actually seem to be that much - he slips into his hyperactive alter-ego Cornholio. Part of the transformation involves pulling the back collar of his shirt over his head, holding both hands up, and commencing a quest to find "TP for my bung-hole!"
Whenever Mac from Foster's Home for Imaginary Friends consumes sugar, he gets extremely hyper. How hyper? He once ripped off his shirt, put on camo paint, and started using guerilla tactics to destroy his own birthday party.
In the Space Ghost Coast To Coast episode "Flipmode", Space Ghost gets high on gas fumes:
Space Ghost: Look: bean prints on the wrench. But what is the wrench for?
Moltar:That's for where you were trying to fix the gas leak, and you made it leak.
Space Ghost:Is that where I got all these ideas? 'Cause they're brilliant! Hey, Break all the pipes in the sub for more good ideas! Dive! Dive! Suck on the pipes!
Occurs on The Simpsons. In "Selma's Choice", Lisa drinks the water from a flume ride and declares "I am the Lizard Queen!" in parody of Jim Morrison.
- Also the episode where Bart and Milhouse drink raw Squishy syrup and go on a sugar-induced 'bender'.
- And, of course, the infamous Guatemalan insanity peppers which begin Homer's vision quest.
- Plus the episode where he finds out his middle name is "Jay:" he destroys the hippies' vegetable juice business by accidentally jamming the bottling machine with a novelty flying disc. He makes up for it by picking all the other vegetables and putting them in the juicer, which turn out to be the hippies' "private vegetables;" we see a montage of townsfolk hallucinations and such, and Chief Wiggum tastes it & comments that "it's nothing but carrot juice and peyote."
- Bart goes on another sugar-induced bender with Lisa, when the family are on holiday in London. The shop-keeper warns them that english candy/chocolate "is sweeter than what they're used to" but the pair scoff their faces, and within seconds their pupils are dilated, and chaos ensues.
Teen Titans features a much darker version of this trope when Robin inhales a hallucinogen and believes the assumed-dead Slade to be plotting to destroy the city.
- Bad trip?
Pictured above: Sokka in Avatar The Last Airbender winds up drinking some raw cactus juice in the middle of a desert. Camera switches to Fish-Eye and all he can talk about is how cactus juice is the "Quenchiest!" while offering it to his (much wiser) friends.
- "It's a giant mushroom! Maybe it's friendly!!"
- Immediately after he comes down from this, he decides to lick the fungus on the wall of a cave the group stumbled into. He begins seeing giant "buzzards". The good news is that they are actually there, the bad news is that he is pointing in the opposite direction.
The first episode of Clone High had what ammounted to the entire student body getting drunk on non-alchoholic beer. Even better is Ghandi, who got drunk (and acted the craziest) even though he knew what it was in the first place, since he helped buy it.
- And let's not even start on the episode about smoking raisins, in which a motivational speaker telling the school not to do drugs emphasizes how addicted he was by saying, "I would have smoked anything! I probably would have smoked... I dunno, raisins if I thought it would get me high!" The raisins, believed by everyone to be smokable, become potent mental drugs. It most notably affects Gandhi, who goes on a spiritual quest with a Donkeycorn only to wake up later, completely naked and confused.
Hank Venture accidentally stabs himself with one of Molotov Cocktease's drugged boot-spikes, resulting in him attempting to kill his father with a papier-mache sword.
Abigail and Amelia's uncle Waldo from The Aristocats, who was thrown out of a restaurant after a failed attempt at cooking. He had been basted (more like marinated) in white wine. "Oh, you are just too much!" "You mean he's had too much.

Truth In Television

An Austrian reporter got drunk while doing a report on mead, having to take a sip of the stuff before speaking. Several takes later, and he was hosed.
MMA fighter Luke Cummo is notorious for his stringent Lifefood dietary habits, but after getting a second-hand marijuana high, he devoured a plate of chicken wings, which affected his metabolism and contributed to his DWI arrest.
- Second-hand marijuana high. Yeah...
Sex columnist Dan Savage wrote in one of his books that something like this happened to his mother once. Dan's partner was making margaritas at a family gathering and Dan's mother was acting loopy after just one glass. It turns out the margarita "mix" already had tequila in it, and Dan's partner hadn't realized this (only wondered why the "mix" was so expensive) and had bought a whole bottle to add to it...
This troper's aunt had this experience at a party where the primary drink was a martini. My olive loving aunt, being underage, was very carefully not drinking, but she was going around asking everyone for their olives. Apparently no one at the party saw fit to inform her that the olives were placed in the drink to suck up alcohol, and watched as she merrily got blitzed. Then there was the police officer that pulled her over on the way home....
This is how The Beatles got introduced to acid. John and George were visiting their dentist/friend for dinner one night in April 1965, and he spiked their coffee with the stuff. They liked it enough to share it with Ringo. Paul was reluctant, holding out for about a year before breaking down and trying it. He still preferred weed.