[[caption-width-right:274:We've wiped it off the face of the planet, [[AndThereWasMuchRejoicing and that's awesome!]]]]

->''"We must scour them from the stars before they do the same to us."''
-->-- '''Chaplain Ortan Cassius''' on the [[HordeOfAlienLocusts Tyranids]], ''TabletopGame/{{Warhammer 40000}}''

You know how most wars end when one side gets what they want, or stops caring, or the other side surrenders? This is not that kind of war. This is a war where the only possible outcome is the utter annihilation of the other side. This isn't like many cases of GoodVersusEvil either, where one side wins forever and there's sugar and gumdrops for the rest of eternity[[note]](Or EvilOnlyHasToWinOnce and you get a Crapsack VillainWorld)[[/note]], this is two sides fighting to the death for reasons [[BlueAndOrangeMorality that cannot be summed up]]. Other options are neither explored nor put forth as viable in any way. Don't expect either side to feel guilty either.

This is when ''both sides'' have '''no issues''' in trying to destroy the other side, and the only way that the war will end is with one side's destruction. Peace is not an option, and the only end is when the other side is destroyed entirely and there are no survivors. It may not even be a war: it may just be a natural enemy that is a constant danger to the {{Heroes}}, like the ZombieApocalypse. Don't expect AnAesop or musing about how war is terrible or TheHero is [[HeWhoFightsMonsters becoming like their enemies]]. There won't be an [[GenocideDilemma agonizing decision about whether or not it's okay]] to [[CurbStompBattle annihilate enemy forces if the chance arises]]. These enemies aren't just okay to kill individually like [[WhatMeasureIsAMook Mooks]], these enemies are okay to '''exterminate''' in their entirety. However, one side keeping the other around as [[ImAHumanitarian food]] or [[FaceFullOfAlienWingWong nurseries]] fits in as well.

Frequent users include: ZombieApocalypse, BugWar, RobotWar, HordeOfAlienLocusts, CreatureHunterOrganization. Compare AlwaysChaoticEvil for when TheHero consider the enemy to be guilt free, but don't engage in a protracted war. Compare FinalSolution, which isn't necessarily a war or an instance of BlueAndOrangeMorality or one side does it but the other side is unwilling to. May eventually wind up with WouldBeRudeToSayGenocide. Compare DoUntoOthersBeforeTheyDoUntoUs. Also compare {{Dehumanization}}, when one or both sides see the other as an "inferior race/species/creature".
!! Examples


[[folder:Anime & Manga]]
* ''Manga/{{Mushishi}}'', while Ginko is normally a FriendToAllLivingThings and incredibly forgiving to even the most violent or dangerous mushi, his response when confronted with a species of mushi that exists solely by preying on people is to explain calmly that humans and that breed of mushi cannot coexist, and humans are stronger.
* In ''Anime/{{Gunbuster}}'', the space monsters are described as a galactic "immune system" trying to wipe out the "disease" of humanity. Humanity is aware that their winning may carry consequences for the galaxy, but decides "Fuck that, we're gonna try to survive anyway."
* ''Anime/MobileSuitGundamSEED'': The war devolved into this after the destruction of the Eurasian military forces at JOSH-A, the Earth Alliance was quick to adopt extremely dubious policies like using drugged up SuperSoldiers to keep up with Zaft's genetically enhanced ones, and ZAFT used Genesis to microwave their enemies alive.
** The Veigans and Earth Federation Forces also apply in ''Anime/MobileSuitGundamAGE'', all of the Veigans are fanatically loyal to Elzecant and the Earth Federation knows nothing short of the extermination of the Veigan will stop them.
** Orga's policy towards the enemy in ''Anime/MobileSuitGundamIronBloodedOrphans'' after Biscuit's death at the hands of Carta when Mika goads Orga to a more ruthless direction. This puts them on a much more ruthless and suicidal approach to fighting their foes in battle. The focus of the brutality can be felt after the Turbines were nearly massacred by Iok and Jasley killing Lafter to spark off a violent reaction from Tekkadan which in term resulted in a brutal counterattack without compromise for anyone, even the normally sane Human Debris pilots Nadi and Dante gave Zack a cold glare for suggesting mercy.
* This is ''not'' the case in ''Manga/{{Superior}}'', but most side characters think it is, as does the female lead. The primary conflict between her and the male lead is over whether a peaceful solution is possible. (To make matters worse, they're supposed to be leading opposite sides of the fight--[[InLoveWithTheMark she argues with herself quite a bit over why she hasn't just killed him if she's so certain he'll have to die eventually]].)
* Galactic Alliance vs. Hideauze war in ''Anime/GargantiaOnTheVerdurousPlanet'' definitely feels like this. And at least the Alliance is desperate enough to employ [[DesignerBabies artificially grown]] {{Child Soldier}}s like the protagonist.
** Then it's revealed that [[spoiler: the Hideauze are genetically altered Humans. Suddenly, Ledo begins feeling a lot of guilt.]]
* The primary conflict between humanity and the [[HumanoidAbomination Titans]] in ''Manga/AttackOnTitan''. Humanity is on the brink of extinction, and the protagonist's stated goal is to wipe the Titans from the face of the earth so humanity can be free again. Then it becomes complicated, zigzagging all over the place. [[spoiler: At least some of the Titans are actually humans with a LovecraftianSuperpower, utilizing a trio of {{Tyke Bomb}}s to carry out the extermination. All three begin to crumble under the guilt of their actions, revealing the enemy isn't as mindlessly evil as it seemed. Then the protagonists learn that ''all'' Titans are human, merely innocent victims merged with a monster and unable to control their actions. The senior members of the Survey Corps are deeply shaken by this revelation]].
** Later on, this trope applies to [[spoiler: the Marley vs. Eldia conflict. Marley, at the very least, seems to not care about civilian deaths so long as they can get rid of the Eldian empire as well as Paradis Island and its inhabitants. If recent chapters are any indication, Eren is willing to kill civilians in order to make a statement to the enemy.]]
* Manhwa/WitchHunter has a GuiltFreeExterminationWar on ''both'' sides of the conflict. The human side began to kill witches as a new and powerful religion that spoke against them began to spread, leading to the death of countless mostly innocent witches. In answer to this, the witches began ''their'' own war against the humans, wiping out whole countries using their magic and powerful familiars. The humans in answer to this, started an Organization called WH, made up of powerful humans and witches, with the stated goal of capturing and restraining as many witches as they can, locking them up and draining them of their powers. The main problem is that many of their more powerful non-witch members ''despise'' witches for their actions and kill as many of them as they can, and also wish to kill the ones that fight for ''their'' side.
* One of the central themes of ''Manga/TokyoGhoul'' explores the consequences for both sides, when this sort of attitude is in full force. Since Ghouls can only eat human (or Ghoul) flesh, the majority adopt an attitude that devalues life in order to deal with eating sentient beings to survive. Humanity has passed the Ghoul Countermeasure Acts, requiring the extermination of Ghouls and harsh punishment for any human that fails to report one. Most people don't even realize that Ghouls are people, considering them inhuman monsters that may mimic human appearance but not seeing anything wrong with torturing or killing small children if they are Ghouls. Reality is more complicated, and the series focus on a human turned into a HalfHumanHybrid and taken in by a group of [[VegetarianVampire peaceful Ghouls]] that scavenge dead bodies to survive. Kaneki comes to realize the cruelty of the endless cycle of killing, with humans and Ghouls alike suffering because of it. Encountering him makes Ghoul Investigator [[WorthyOpponent Amon]] begin to question everything he's been taught, while InterspeciesRomance repeatedly plays a significant role in the story more than once. The finale of the original series brings this full circle, with [[spoiler: the CCG raiding Anteiku and both sides left absolutely devastated while the militant [[AntiHumanAlliance Aogiri]] benefits from the carnage]]. The utter pointlessness of it all is driven home by a pair of Investigators wondering if anyone could be considered the victor, while the sequel shows that the consequences have made things worse for humans and Ghouls alike.

* In the ''ComicBook/MetabaronsUniverse'', humanity is threatened by an alien invasion. Rather than waste resources fighting a war, they agree to a battle between two champions. The loser commits "immediate racial suicide." This is perfectly in keeping with the ''Metabarons'' storyline, where everything is cranked UpToEleven.
* The ''ComicBook/SpiderMan'' series presented a case of this in The 1990's Planet of the Symbiotes storyline. The whole series went as far as to portray the Symbiotes as a HordeOfAlienLocusts dedicated to finding and taking over the bodies of other sentient beings to feed on their life forces until they become decayed hollow shells. The Venom symbiote and its progeny are apparently the only ones who care for their hosts due to a form of mutation. At the end of the series, Eddie Brock as Venom manipulates Spider Man and Scarlet Spider into finishing a plan to send out a telepathic scream that would create enough pain and despair that the Symbiotes would commit suicide. Spider Man feels guilty about essentially causing the genocide of an entire race, but is given the {{Aesop}} that the ends sometimes do justify the means if the species eliminated is a AlwaysChaoticEvil race dedicated to destroying worlds to feed itself. It's even more jarring considering the Aesop was delivered by Mary Jane Watson of all people.
* ''ComicBook/NemesisTheWarlock'': Subverted. Torquemada's holy war to exterminate all alien life is treated as very bad, but this does mean that Nemesis has no qualms about exterminating humanity right back. His ally Purity has to convince him that there's something worth saving after all, reminding him that she's human too.
* ''ComicBook/PaperinikNewAdventures'': Xadhoom's war against the Evronians: they are an imperialistic AlwaysChaoticEvil species who destroyed her homeworld and exterminated almost all of her people, so she's going to exterminate them in return. It's deliciously karmic to see the BigBad of the comic so scared out of their wits by [[GenocideBackfire a problem they themselves created]].

[[folder: Fan Works]]
* Invoked in ''FanFic/TheLastRingbearer'': Orcs of Mordor are actually intelligent and reasonable HumanSubspecies, who were wiped out by barbaric humans and elves, but Middle-Earth historians retroactively justify their genocide by declaring them being AlwaysChaoticEvil monsters.
* ''FanFic/ThePrayerWarriors'' have no qualms with wanting to wipe out all their enemies, since their version of God told them to do so, and they don't believe their enemies are humans, anyway.

* ''Franchise/{{Terminator}}'': In the future, [[RobotWar humans vs the robots]]. Skynet sees humans as worthy of extinction and programs its robot troops to kill any in their path without compunction; the humans' only real way to win the war is to destroy Skynet and its armies for good. This is however subverted by the intelligent Terminator models, who have the potential to understand the value of life. This feature is routinely deactivated by Skynet for field models [[RobotsEnslavingRobots to make it easier to control them]].
* ''Film/IndependenceDay'': The aliens, in keeping with their HordeOfAlienLocusts nature, have no issues wiping out entire cities full of people. [[spoiler:Humanity has no issues returning the favor for the alien mother ship.]] The US President actually does probe for peace even after they destroy every major city on Earth, with an alien that had just slaughtered a team of scientists no less; the response was a MindRape that would have killed him if the alien wasn't shot, and it showed him that their entire civilization is based upon this, moving from one world to another, wiping out the natives, using up all the resources, and then moving on to the next planet to repeat.
** The second film maintains this, as the queens objective is still to harvest the Earth, there's just a side note of revenge. The humans by the end get invited to a coalition of other species that had survived the harvesting of their planets, with the purpose of hitting the Harvester aliens at their home world and exterminating them in turn.
* In ''Film/PacificRim'', the Kaiju are here to kill humanity. There's nothing to hold humanity back from punching them in the face in turn, and eventually [[spoiler: sending a nuclear warhead back through the interdimensional gateway to hit the Kaijus' creators]].
* The Martians in Film/MarsAttacks, they invade Earth and massacre everyone with glee. Then the humans in turn do the same to the invaders when they figured out their weakness.
* In ''Film/ThorTheDarkWorld'', both the Asgardians and Dark Elves are okay with exterminating each other to the last. This is explained because the Dark Elves, created before light itself existed, can only really survive in the dark. Since every other race needs light to survive, it makes it an Us Or Them war for both sides. Even Odin and the new, conscientious Thor never really pause and say "There must be a peaceful way...right?"
* ''Film/{{Aliens}}'': After the first engagement with the Xenomorphs leaves most of the Colonial Marines dead, Ripley convinces the remainder to exterminate the alien monsters by [[ItsTheOnlyWayToBeSure firing a nuclear missile at them from orbit]]. The Xenos are an omnicidal species adhering to a BlueAndOrangeMorality, a species that is heavily implied to be a genetically engineered bioweapon that is supposed to completely supplant any sentient lifeform in the area it infects. The only person to object to this is a CorruptCorporateExecutive with a stake in weaponizing them.
* ''Film/EndersGame'': The premise of the movie revolves around this, as the humans seemed to fight a HopelessWar against the Formics. [[spoiler:[[DeconstructedTrope Then the movie then sends a fist towards the viewers faces]] when the [[HumansAreTheRealMonsters humans]] themselves became too bloodthristy for their own good that they tricked [[ChildSoldier Ender]] into [[ApocalypseHow/{{Class6}} wiping out the entire Formic race]].]]
* ''Film/StarshipTroopers'':
** The film satirizes this by having the Humans take a disturbing amount of glee in the destruction of the InsectoidAliens. The propaganda reel after the alien meteorite destroys Buenos Aires particularly demonstrates this. One of the survivors looking straight into the camera and earnestly declaring, “The only good bug is a dead bug!” The next clip of people at home “doing their part” is of school children crushing cockroaches and their teacher maniacally cheering them on. The one journalist who suggests that compromise is possible if Humans stay out of Insect-populated worlds is immediately shouted down.
-->'''Rico''': I'm from Buenos Aires, and I say, '''''Kill'em all!'''''
** At the end of the movie, when they [[spoiler: capture the Brain Bug, Carl psychically merges with it to learn what it’s thinking. When he announces that it’s afraid, rather than feeling empathy or sympathy, all the soldiers triumphantly cheer!]]
** It's not just the humans who are gleefully genocidal, by the way--[[NotSoDifferent The Bugs feel the same way]]. When one of them talks through a [[PuppeteerParasite possessed human]] in the second film, he expresses his extreme disgust for Humanity's lack of a HiveMind and compares them to a virus that has to be exterminated completely. While the humans are clearly the agressors, it's doubtful that peace would even be possible even if the humans did leave the Bugs alone.
* In ''Film/{{Gremlins}}'' and ''Film/Gremlins2TheNewBatch'', the only strategy against the Gremlins is to kill them all, given that their sole aim is ChaoticEvil.

* ''Literature/PandorasStar'' includes an implacable hive mind whose only motivation is to be, not just the only sentient being in the universe, but the only life form at all, and has no problem wiping out humanity. Given that its entire species consists of a single individual, victory for humanity would by definition leave it extinct.
* ''Literature/{{Lensman}}'' stories by E.E. "Doc" Smith: The conflict between Civilization and Boskone was a fight to the death. Neither the Galactic Patrol nor the pirates of Boskone ever surrendered to the other, and entire planets were destroyed in the conflict. The justification was that the Eddorians (the beings behind Boskone) are completely amoral and implacable beings from another dimension who consider plundering whole universes to be not just acceptable but ''de rigeur'' (they did just that with the last dimension they inhabited), and their hierarchy was based upon that philosophy.
* ''Literature/StarshipTroopers'' by Creator/RobertAHeinlein: Neither the Terran Federation or the [[BugWar Bugs (Arachnids)]] have any qualms about wiping the other out in their drive to expand across the universe. The major effort and a significant part of the plot is dedicated to capturing "brain" Bugs, in order to understand their psychology and see if it is possible to reach an understanding. It's after succeeding in this task that humans conclude that the only way to end war is to wipe Bugs from the face of the universe. This is one of the few things retained by [[Franchise/StarshipTroopers all]] of the adaptations.
* ''Literature/OldMansWar'' by John Scalzi initially presents humanity in a constant state of war with other species for colonies, using a similar justification to that of Literature/StarshipTroopers (one of Scalzi's inspirations) in that "this galaxy ain't big enough for the two of us". But [[spoiler: it is subverted in later books by the Conclav]]
* ''Literature/LordOfTheRings'': The humans and elves vs the armies of Mordor. The closing section of ''Literature/TheHobbit'' talks quite pleasantly about the goblins being hunted into extinction in the Misty Mountains, without any hint that anyone ''could'' have a problem with this (except, presumably, a large number of dead and therefore irrelevant goblins.) Out-of-universe, author Creator/JRRTolkien was ''very'' ambivalent about this particular plot point, and [[FlipFlopOfGod went back and forth]] about whether the orcs were really as AlwaysChaoticEvil as they seemed right up until his death.
** Nearly every major battle in the trilogy ends in an aftermath where the surviving human enemies are taken captive and treated well, while the orcs are exterminated to the last, and unceremoniously burned. This is even brought up in ''Two Towers'' by two orcs who comment that the only way for them to survive is through Sauron's victory, even though they aren't all that fond of the Dark Lord, themselves.
* The Franchise/DoctorWhoExpandedUniverse novel ''Sky Pirates!'' revealed that the Timelords had a couple of wars like this in the distant past, where the opponents were just so utterly different each side regarded the other as an EldritchAbomination to be utterly eliminated. [[CaptainObvious The Timelords won]].
* Literature/TheBible is the UrExample, as the Hebrews are ordered by {{God}} to displace and destroy the Canaanite people. This is supposed to be okay because they practice child sacrifice and temple prostitution, and also [[BecauseDestinySaysSo because the 'curse of Canaan']] [[FateAndProphecyTropes says it will happen]]. It's up to the reader whether this is ValuesDissonance or not.
** The Orthodox Jews consider even today the extermination of Amalekites (and their assumed descendants) as a ''mitzva''.
** Technically, only the Amalekites were supposed to be destroyed... that is, the rest of the nations were given the option to clear out. Allegedly, one did.
* In ''Literature/CodexAlera'', the conflict between the Alerans and [[HordeOfAlienLocusts the Vord]]. Most of the Vord are mindless beasts under the control of their Queens, which have a genetic imperative to wipe out any other species and expand to consume all. There is also the war between the Vord and [[spoiler: the Canim]], which ultimately ended with [[spoiler: the Canim being almost exterminated]], save for the ones that [[spoiler: Tavi and Varg were able to evacuate]].
* Related to the {{TabletopGame/Starfire}} example in Tabletop Games is the novels based off it by Creator/DavidWeber and Steve White. In addition to the war with the Rigellians as part of the back story there is the war with the Arachnids or Bugs. No attempt at communication succeeds and they view other sentient species as nothing more than food. The only world that is not subjected to massive orbital bombardment is the homeworld of one member of the Crucian Alliance which is liberated the hard way.
* The ''Literature/InheritanceCycle''. The AlwaysChaoticEvil Ra'zac are exterminated, first by the Riders and then by the protagonist. The moral rectitude of this action is never questioned.
** Granted, they seem to feed exclusively on humans.
** To expand: the "moral rectitude" of this is never questioned because the Ra'zac are a race of apex predators, sentient ones at that, whose sole food and prey is humankind, and who take [[ForTheEvulz direct, perverse joy]] in killing humans--[[WouldHurtAChild especially children]]. One may question the author's intent all one wants, but the world is better off with the Ra'zac gone. The same way the real world is better off with Smallpox gone.
* ''Literature/EndersGame:'' [[spoiler:Subverted with both sides due to a major misconception. The buggers, being a hive-mind, didn't realize that humans were individually sentient. When they realized their mistake after killing millions of humans they felt so guilty that they let humanity wipe them out with the exception of one pupal Queen. On the other hand, when Ender destroyed the bugger homeworld, he believed it was merely a simulation and so felt no guilt about his actions until he learned after the fact that he had committed xenocide for real]]. Card's later ''Ender'' books establish a scale of "alienness" between individuals and species, where on the farthest end of alienness it becomes possible to acknowledge that avoidance or xenocide are the only options for interaction between species because they simply cannot comprehend one another. The moral burden is upon the would-be exterminator to make certain there's no way to communicate with (or just avoid) the other species before committing to the extermination war, however.
* Franchise/StarWarsExpandedUniverse
** ''Literature/BlackFleetCrisis'': The main villains are the Yevetha, who are your typical ScaryDogmaticAliens -- they're well able to learn Basic and sent someone to meet with the New Republic, fair enough, but they only do this as the prelude to starting a war with it, in which we see that they are ''impossibly'' xenophobic and culturally narcissistic; their culture had developed and become advanced with not a single recorded speculation that there was other intelligent life in the galaxy, and FirstContact only convinced them that everything else was unworthy vermin which had to be exterminated. (Granted, their first contact was with the Empire, who immediately enslaved them.) Every member of the species was prepared to die fighting, but after winning the New Republic just destroyed all of their ships and left them stranded on their world. Years later, when the [[Literature/NewJediOrder Yuuzhan Vong]] with their similar if not ''quite'' as extreme xenophobia showed up, the Yevetha refused to submit and were hunted down and systematically killed.
** The Bothans have this as a little-used[[note]]exactly three times in their entire recorded history[[/note]] cultural practice called ''ar'krai''. Every able Bothan is required to volunteer for military service in order to not only slay every last member of the offending group or species, but [[ThereIsNoKillLikeOverkill grind their homeworld to dust]]. They declare ''ar'krai'' against the [[Literature/NewJediOrder Yuuzhan Vong]] after perennial ObstructiveBureaucrat Borsk Fey'lya pulls a HeroicSacrifice during the fall of Coruscant.
*** This example actually provides a bit of {{Deconstruction}}: the rest of the [[TheFederation Galactic Alliance]] isn't quite so giddy about genocide, and finds a ([[EarnYourHappyEnding relatively]]) peaceful solution to the war. This causes some tension between pro-ar'krai Bothans (who form a political party called [[FinalSolution True Victory]]) and the rest of the galaxy, and possibly contributes to [[spoiler:Bothawui seceding from the Alliance]].
* In ''Literature/LastAndFirstMen'' the Fifth Men kill off the native Venusians without a second thought. Of course, by then Earth was dying and Venus had to be [[{{Terraforming}} terraformed]] to be inhabitable. Earlier the Second Men used a bioweapon to wipe out the Martians who had been invading Earth for several thousand years, but it destroyed their civilization as well.
* The Martians in ''Literature/TheWarOfTheWorlds'' have this attitude toward humanity; the humans are too busy being terrified and/or dying to return the sentiment.
** In Garrett P. Serviss's unauthorized sequel ''Edison's Conquest of Mars'' the humans fly to Mars and cheerfully wipe out the Martians who tried invading Earth. Technically it's an accident, but nobody's really bothered by the extermination of a whole species.
* In Creator/WenSpencer's ''[[{{Literature/Tinker}} Wolf Who Rules]]'', Windwolf insists on this, though feeling more qualms that he shows, because of the onis' total LackOfEmpathy and the way they breed like rabbits.
* The "Holy War" that annihilated the race of the Ghouls in E. R. Eddison's ''Literature/TheWormOuroboros'' is treated that way by the polite nations of the world of Mercury. Lampshaded when Lord Gro tries to mine the genocide for anti-Demonland propaganda and is rebuked by the Red Foliot (a peaceful and mild-mannered chap), who assures him that the extermination of the Ghouls was most certainly a praiseworthy heroic. As the Ghouls were cannibal sea-raiders, it can be inferred that the Ghouls felt no different towards the other races of Mercury.
* ''Literature/MonsterHunterInternational'': The vast majority of the undead fall into this as they fall under the "humans are tasty" clause. Many other creatures do as well, like fishmen which like to [[FaceFullOfAlienWingWong lay eggs in live human beings]]. While the government takes this stand in general against most non-humans, they're aware that not every supernatural being are inherently incapable of getting along with people, they just use it for black mail.
* Larry Niven's ''Literature/KnownSpace'' universe: any war among [[AbusivePrecursors Pak protectors]] is one of these. The protector-stage Pak are hyper-intelligent and, at the same time, have incredibly powerful, genetically-hardwired instincts that drive them to fanatically protect their own offspring and close relatives and exterminate anything or anyone else. While the Pak can, and do, wipe out other threatening species, their killer instinct is strongest for other Pak who are not in their own bloodline, because they "smell wrong" (this also applies to their own descendants who are mutants, a relatively common occurrence on the Pak homeworld, which abounds with radiation both as a consequence of being near the galactic core and having loads of nuclear fallout from very frequent nuclear wars). Pak protectors are rational enough to form alliances with non-relatives for mutual advantage, but the very ''instant'' there is an opportunity for betrayal, a Pak will take it. The Pak have wrecked their homeworld with constant wars of mass destruction, including nuclear weapons and exotic anti-nuclear countermeasures, and biological weapons (they are quite fond of genetically-engineered plagues which sterilize certain genotypes, as unlike nukes plagues leave behind land and resources which can be seized).
** [[spoiler:Even when the Pak flee their homeworld ahead of the core explosion, the Pak fleet is in a constant state of war with itself, which often spills over on planetary systems on their path, which the Pak fight to plunder for supplies.]]
** When a Pak Protector comes to one of their lost colonies in the outer edges of the galaxy he finds that the Protectors died off and the colonists evolved into a species that is intelligent enough to build starships before becoming Protectors, but they smell wrong so they must be exterminated. He captures one of the mutants for interrogation and accidentally turns him into a Protector, said mutant learns everything about the Paks, then kills him as a threat to his children. Fortunately [[spoiler: human]] Protectors are also rational enough to realize that unrelated members of their species aren't automatically a threat.
** Three billion years earlier the galaxy had been conquered by the Thrint, a race with the ability to telepathically brainwash any non-Thrint species. The only exception were the Tnuctipun, a race of hyper-geniuses who managed to fake being under Thrint control until they were ready to rise up. The war was one of absolute extermination, ending with the losing Thrint triggering a doomsday device that killed ''all multi-cellular life in the galaxy''.
* The Final War with the Melconians in Bolo. The entire war becomes a war of genocide with the only strategy being "kill everything of the enemy's before he kills yours." And the authors do mean EVERYTHING.
** The fact that everyone that survived the war was horrified at what happened, with what little remains of both sides agreeing that it was a terrible thing, shows that it wasn't really guilt-free at all.
* ''Literature/TheIronDream'' is a {{deconstruction}} of this trope, in a DoesThisRemindYouOfAnything manner -- in an AlternateHistory, a sci-fi writer called UsefulNotes/AdolfHitler writes a popular sci-fi pulp novel in which the hero is on a crusade to exterminate all mutants who are contaminating his race.
* {{Deconstructed}} in ''LightNovel/MaoyuuMaouYuusha'' - while the story is introduced as a ''[[EveryoneCallsHimBarkeep very]]'' stereotypical HighFantasy with BlackAndWhiteMorality, not only does "demons are evil" turn out to be propaganda (with demons believing the same about humans), but the Demon King believes that [[WonTheWarLostThePeace humans would end up worse off if they actually won]]. [[spoiler:What's more, the highest ranks of the Human Church and the Blue Demon Clan (the most influential anti-demon and anti-human factions respectively) are actually working together, using the war to achieve their own objectives.]]
* In ''[[Literature/TheChroniclesOfPrydain The High King]]'', Taran uses the sword Drynwyn to [[spoiler:kill off ''all'' of the [[OurZombiesAreDifferent Cauldron Born]], previously thought to be unkillable (when he ran through ''one'' of them, ''all'' of them fell at once because Dyrnwyn actually broke the curse that kept them undead). Since the Cauldron Born were made from the dead being dragged into undead servitude, this is portrayed as a MercyKill.]] The very end of the story also reveals that [[spoiler:all of the gwythaints were dead as well. This is mentioned in passing, which is a bit jarring when one remembers that the gwythaints distinctly ''weren't'' an evil species and only served Arwan through him torturing them as fledglings, and that Taran is pretty easily able to win the loyalty of one by sparing its life and healing its hurt wing.]]
* Subverted in ''Literature/TheDresdenFiles'' with the war between the Red Court of Vampires and the White Council of Wizards. Initially, it seemed to be one of these - [[AlwaysChaoticEvil Red Court vamps only gain their power after their first kill]], and were responsible for starting the war in the first place ([[UnwittingPawn their manipulating Harry into striking first notwithstanding]]) in order to wipe out the White Council. In ''Literature/{{Changes}}'', [[spoiler: Dresden killed all of the vampires with a blood curse that affected everyone who shared a blood link with the Red King: the entire court.]] However, subsequent books point out that this action [[spoiler: also took out the [[PhlebotinumRebel Order of St. Giles]] as collateral damage, created an EvilPowerVacuum that still hasn't been cleaned up, and has inarguably left the world in a worse and more unstable position than they were with the Red Court at full strength.]]
* Creator/RoaldDahl's ''Literature/TheWitches'' features a thoroughly horrific WitchSpecies as AlwaysChaoticEvil antagonists whose prime directive is to exterminate every child on Earth in various nightmarish ways. At the climax of the story, a boy and his grandmother hijack the witches' ultimate weapon and use it to massacre all the witches of England along with the [[MonsterLord Grand High Witch]] herself. The book concludes with our heroic duo laying out a plan to wipe out the rest of the world's witches using the same weapon.
* The war against the Pitar in the Literature/HumanxCommonwealth novel ''Dirge'' becomes this unintentionally. When they are exposed as having [[LeaveNoSurvivors murdered every human]] on a colony planet and [[OrganTheft extracted the females' reproductive organs]], they retreat to their fortified home system and fight to the point of their own extinction. They're eventually exposed as {{Absolute Xenophobe}}s who deplored the existence of "inferior" races and, [[AlwaysChaoticEvil without exception]], chose SuicideByCop rather than surrender to a human. The humans oblige.
* In ''Literature/XeeleeSequence'', the Xeelee have been at war with the Photino Birds for practically the entire existence of the universe, and since the two sides are composed of incompatible forms of matter (the Xeelee baryonic matter, the Photino Birds dark matter) that require the same thing to survive (stars) but in mutually exclusive forms (Xeelee need black holes, Photino Birds white dwarfs), it automatically becomes one of these since the only way for one to survive is to wipe out the other to protect their vital energy source.
* ''Literature/MidnightTides'', book five of the ''Literature/MalazanBookOfTheFallen'', opens with the tail end of a mutual extermination war between the K'Chain Che'Malle and the allied Tiste Andii and Tiste Edur forces. The K'Chain Che'Malle have just lost but it's obvious that both sides went all-out on each other, going as far as employing suicide commandos and field-spanning destructive sorceries. The reason? The Tiste didn't want any competition when they set out to settle this world and the only thing both sides would've agreed upon would've been that there's not space enough for both races' egos.
* In the ''Literature/JohnCarterOfMars'' series, particularly the earlier books, a number of Barsoomian races and species get fought or hunted to extinction with little thought to the consequences. With Barsoom being a borderline DeathWorld kept artificially viable by a single "atmospheric plant", there is generally an attitude that the less nations or species there are, the more resources will be left for the survivors.

[[folder:Live Action TV]]
* ''Series/DoctorWho'':
** The war between the Thals and the Kaleds would only end with one destroying the other. The Thals "won" by destroying the Kaled bunker thanks to information leaked to them by Kaled scientist Davros - who then turned his creation, the Daleks, on the Thals, thus destroying them as well.
** The Daleks themselves are utterly convinced that every single non-Dalek lifeform in the universe must be exterminated; they are also genetically engineered to feel "no emotion but hate", and once engaged in a mutual civil war of annihilation when Davros made a new breed with only trivial, aesthetic differences between them. The Doctor himself varies on the issue; on rare occasions he will try diplomacy or some more peaceful tactic, but on plenty of others he's more than ready to literally KillEmAll, and is horrified when JokerImmunity kicks in and a handful, or even a lone, Dalek survives.
*** As was said in the new series episode where the Cult of Skaro first encountered the Cybermen: "THIS IS NOT WAR! THIS IS PEST CON-TROL!"
** The Last Great Time War seems to be this as well, from what little we know of it. The Time Lords and Daleks seemed to be out to simply destroy each other, and at some point the Doctor decided that both sides had to be destroyed. There is, however, ''lots'' of guilt on his end due to the billions of innocent Gallifreyan lives that were lost, not to mention at least some reason to believe he [[IDidWhatIHadToDo was out of alternatives]]; the implacable nature of Daleks had already been shown, and "The End of Time" showed the Time Lords had become just as bad. The guilt is examined at length in the MilestoneCelebration "The Day of the Doctor", in which the Tenth and Eleventh Doctors have to confront their past self's actions, accept them, and [[spoiler: then Eleven's companion Clara Oswald, horrified by their acceptance, convinces them and the War Doctor that they can find another way to end the war; all of the Doctors through Twelve manage to hide Gallifrey in a pocket universe, an act that only destroys the Daleks attacking the planet at the time]].
** The audio drama ''Doctor Who and the Pescatons'' has its reliance on this trope to be one of the many reasons it's considered SoBadItsGood - the Doctor and Sarah commit genocide against a race of shark people who are trying to find a new planet to live on after the destruction of their own world on the grounds that "[[AlwaysChaoticEvil they are a truly evil race]]", and [[OutOfCharacterMoment neither show any moral conflict or remorse about it at all]]. This should be strongly contrasted to the Fourth Doctor's attempt to commit genocide in "Genesis of the Daleks", which was ''not'' guilt-free at all, and he was unable to go through with it.
* The humans on ''Series/{{Battlestar Galactica|2003}}'', for the most part, believe this since the Cylons wiped out 99.99% of humanity in the pilot. They will frequently torture and kill captured Cylons because they're "[[JustAMachine just machines]]" and don't really feel pain. People who object are typically just written off as incredibly naive or crazy. [[spoiler: During the series, however, this attitude decreases to the point where the humans and some rebel Cylons form an alliance against the rest of the Cylons]].
* ''Franchise/StargateVerse'':
** ''Series/StargateSG1'': the Replicators are (initially) non-sentient, will consume anything and everything to replicate, and the only way to stop them for good is to destroy them, so the war with them inevitably becomes this. A different type of Replicators appear in ''Series/StargateAtlantis'', and this applies to them as well.
** ''Series/StargateAtlantis'': the fight against the Wraith is generally seen as an us-or-them game as well -- the Wraith certainly aren't out to ''kill'' all humans, and in fact go out of their way to use non-lethal weaponry unless a human civilization particularly resists or threatens them... but that's only because humans are their food supply, and treat a war with us as being like a farmer fighting his own cattle. Later on, Dr. Beckett develops a virus that turns Wraith into humans, but it wears off without regular boosters and is nigh-impossible to deliver. Even later the Replicators and renegade Asgard force the Atlantis expedition into multiple EnemyMine situations with one Wraith faction and at one point offer them an experimental treatment that would allow them to live without feeding on humans.
* [[MagnificentBastard Scorpius]] spends a lot of time in the later seasons of ''Series/{{Farscape}}'' trying to convince Crichton that the Scarrans want to wipe out or enslave everyone, and have to be stopped by any means necessary. Considering that they started wiping out as many species as possible during "The Peacekeeper Wars", Scorpius was probably right. But then Crichton figures out [[TakeAThirdOption a third way]] that actually ends the war with all sides still intact...''including his'', which was his big motivation for pulling it off.
* ''Series/GameOfThrones'': The "War for Dawn" and the "Long Night", which occurred thousands of years in the past, was fought between the King of the North and the White Walkers and their undead army. It ended in a defeat for the Walkers and forced them to retreat back to their arctic homeland, but they eventually return for another war against the living. There's literally no possibility of a truce and this war will only end when one side is completely obliterated, since the White Walkers are essentially a LivingWeapon gone wrong and their only purpose is to kill every man, woman, and child.
* ''Series/FallingSkies'': In the finale, [[spoiler:Tom kills the Espheni Queen, and it's indicated that the entire Espheni race is wiped out, down to the last one. Its also indicated that all the Skitters (who mind you are slaves) are also wiped out. This is treated as a completely good thing.]]

[[folder:Tabletop Games]]
* In ''TabletopGame/{{Warhammer 40000}}'', nearly every single race has reasons and plans to exterminate every other race.
** This is quite literally the Imperium's standard colonization protocol: drop a few [[BadAssArmy Imperial Guard]] regiments, exterminate all sentient life on the new planet, ship colonists in. The stone age Tau only escaped that fate thanks to a freak warp storm.
** The [[TheFederation Tau]] don't automatically exterminate every species they come across, preferring to integrate and "adopt" other species as they discover them. Still, when they do encounter a species that they determine unfit or unable to peacefully coexist, they will ruthlessly exterminate them. Considering [[CrapsackWorld the]] [[UpToEleven galaxy]] they live in, this probably happens pretty frequently.
** Tyranids exist to eat, breed and absorb the best characteristics of every species that they can get their claws on -- only characteristics that facilitate those three imperatives, of course.
** Pre-5th Edition, the Necrons served beings that wish to annihilate everything related to the Warp. The Warp is sustained in part by the emotions of living beings. Nothing more needs to be said.
*** Said beings also eat the souls of beings slain by their undead robot minions.
*** In 5th Edition, they just want to conquer and dominate, but are willing to wipe out all life on a colonized tomb world and also capture a lot of people for destructive scientific experiments.
** Orks vs. anyone that isn't another Ork comes down to this. Orks are strongly implied to be a bio-engineered species, essentially {{Super Soldier}}s taken to LivingWeapon levels; they literally cannot understand the concept of ''not'' fighting, and so anything that isn't an Ork essentially needs to be wiped out. There's admittedly no ''malice'' to it, they're essentially a whole species who think "fighting is super awesome fun!" and don't understand that other races don't think this way. Other races, accordingly, treat Orks as the ultimate form of dangerous vermin, a pestilence that needs to be eradicated wherever it appears. Given the fact Orks ''multiply like crazy'' (depends on the edition, but the implication is that they ''way'' outnumber everybody else save for possibly the Tyranids), they have a point.
* ''TabletopGame/{{Starfire}}'' by Task Force Games: The Third Interstellar War between the Alliance (Terrans and Khanate of Orion) vs. the fanatically racist and warlike Rigelian Protectorate. The Rigelians were determined to wipe out the Alliance, and the Alliance was forced to destroy the Rigelians completely to eliminate them as a threat.
* ''TabletopGame/MagicTheGathering'' deals with this whenever [[TheVirus Ph]][[ZombieApocalypse yre]][[CyberneticsEatYourSoul xi]][[FromASingleCell ans]] get involved, especially in ''Invasion'' and ''Scars of Mirrodin'' blocks.
* ''TabletopGame/DungeonsAndDragons'' has the [[EvilVsEvil Blood War]] between the Lawful Evil devils/baatezu and the Chaotic Evil demons/tanar'ri, it's been raging for millenia and is unlikely to end until and unless one or both sides gets totally exterminated. Which is fortunate for everybody else because the fiends could probably wipe out the celestials and everybody else in the multiverse if they weren't so busy fighting each other.
** Beholders with even the slightest morphological differences from one another will always try to destroy one another out of pure, uncompromising bigotry.
** It's [[WouldBeRudeToSayGenocide glossed over quite often]], but humanity and its allied races are engaged in one with almost every sentient evil-aligned creature in the books. In some cases (such as the [[SlaveryIsASpecialKindOfEvil neogi]], [[ImAHumanitarian illithids, and vampires]]), it's a justified trope: only their extinction will spare humanity from a FateWorseThanDeath.
* Frequent in ''3:16 Carnage Amongst the Stars''. Because it's [[OmnicidalManiac us]] [[BugWar or them]].
* In TabletopGame/GURPSReignOfSteel this is the attitude of ''most'' of the Zonemind computers toward humanity (if not all living things) -- and the attitude of nearly all surviving humans toward the Zoneminds. The only major exceptions are the inhabitants of the British Isles, whose Zonemind ignores them so long as they don't get in its way (the British government can compare with the other Zones nearby, so they know this is pretty much the best situation they could have) and the inhabitants of the eastern US, who think their "tame" Zonemind is a loyal servant and protector (they're wrong about the first, and wrong about the ''reasons'' for the second).
* In ''TabletopGame/WerewolfTheApocalypse'', the Garou war against [[EldritchAbomination the Wyrm]] is framed as this. The Wyrm and its minions are depicted as depraved, irredeemable, and [[OmnicidalManiac determined to destroy Gaia]], making the Garou's savage tactics understandable.
** One of the game's most depraved antagonists was the Seventh Generation, a Wyrm cult that abducts children and uses them as human sacrifices. After ascending the throne, King Albrecht orchestrated a Garou slaughter of Seventh Generation devotees, virtually wiping out the cult.
** The line still subverts it, though. While the forces who've fallen to the Wyrm need killing yesterday, it's made clear the Garou have had times where they haven't been able to tell the difference between "fallen to the Wyrm," "Wyrm-tainted," and "smells of the Wyrm." And yes, there are differences there. As a result, their tactics have resulted in [[NiceJobBreakingItHero a genocidal war that eliminated some of their closest allies and alienated all the others, as well as the destruction of one of their own tribes]], events that they have ''plenty'' of guilt over.

[[folder: Video Games]]
* ''VideoGame/TotalAnnihilation'': Both factions use this and ''have'' to be sure they've wiped the other side out or they'll just rebuild with {{nanotechnology}}. The campaign demonstrates this, since you begin with the last commander unit in the last base on the last held planet and tear apart the entire enemy faction from there.
* In ''Franchise/MassEffect'', variations of this trope are played a few different ways.
** The rachni were hunted to extinction. ([[spoiler:{{Deconstruction}}; they were a peaceful race until they were brainwashed by the Reapers--or possibly the Leviathan.]])
** The turians and salarians used a DepopulationBomb to end the Krogan Rebellion. {{Defied|Trope}}; the genophage was made specifically to avoid this trope, and was originally intended by the salarians to be a deterrent. What the salarians, [[TheSpock impeccably practical]] as they are, seem not to have anticipated is that the krogans would get so demoralised by having their fertility cut to 1% (which, [[ImmortalProcreationClause given how long-lived the krogans are, was calculated to ensure a steady population]]) of its natural level that most of them gave up on reproducing altogether; they either didn't know or overlooked that the plague produced ''a lot'' of [[DeathOfAChild dead newborn krogan]] (according to [[VillainHasAPoint the krogan Clan Weryloc speaker]] in Mass Effect 2). Mordin Solus, a salarian scientist who helped restore the genophage at a time when the krogans seemed to be recovering from it, comes to feel extremely guilty about it when he realises that the krogan species is essentially dying out from ''collective depression.''
** [[PlayerCharacter Shepard]] is personally responsible for wiping out the Collectors. ([[spoiler:{{Reconstruction}}; they were sentient once, but [[CyberneticsEatYourSoul are now mindless]]. However, some do appear in multiplayer after the suicide mission]])
** Shepard is forced to choose HeelFaceBrainwashing or destroying the [[spoiler: heretic]] geth. ([[spoiler:Zig-zagged, PlayedForDrama. Neither side is really portrayed as morally right or wrong (although one gives you Paragon points and the other Renegade points). Killing them does make the GoldenEnding easier to get in ''3'' though]].)
** In general, there's a standing order in [[TheFederation Council Space]] that all [[AIIsACrapshoot AIs are to be terminated on sight]]. The exceptions are those which are authorized by controversial research companies such as Synthetic Insights. Knowing that every organic in the galaxy is united to kill them without a second thought, many synthetic creatures, such as the geth, adopt a similar "shoot first and ask questions later" policy.
** The above two are combined when the quarians throw their entire race into a final war with the geth. ''Somebody'' is getting wiped out, and both sides' hands are so bloody nobody feels too bad about it afterwards either way, maybe bar [[spoiler: the deaths of [[ReasonableAuthorityFigure Tali, Zaal'Koris and Legion]]]]. [[spoiler: There is a third route where they make peace, but it requires [[GuideDangIt a lot of work]] and an OldSaveBonus to pull off.]]
** The Reapers, the central antagonists of the original trilogy, openly view all other species as bacteria, fit only to be purged, enslaved or, in "worthy" cases, [[spoiler: processed into genetic paste to build a new Reaper.]] ([[spoiler:{{Subverted|Trope}} in the Control and Synthesis endings of ''Mass Effect 3''; played straight in the Destroy and Refusal endings.]])
** ''Mass Effect: Andromeda'' seems to be setting up the alien race the kett as targets for one.
* The only option (other than Assimilation Plague) in ''VideoGame/SwordOfTheStars'' before the second expansion added psychology techs that allow a player to force a planet to surrender after just one or two nukes.
* In ''VideoGame/StarFox Assault'' the [[HordeOfAlienLocusts Aparoids]] are exterminated without a second thought. And in at least some of the possible endings to ''Command'' the Anglar are presumably wiped out as well (considering their homeworld is terraformed in a couple endings).
* In ''VideoGame/RatchetAndClankFutureToolsOfDestruction'', pretty much everyone who brings up the subject considers the Lombaxes the "Saviors of the Universe" for completely wiping out the Cragmites. [[spoiler:Granted, it turns out they actually sent them to another universe, but no one else ''knew'' that.]]
* ''VideoGame/{{Starcraft}}'': the [[HordeOfAlienLocusts Zerg]] are a race burdened with a hard-coded biological imperative, instilled by the Xel'Naga, to assimilate and destroy other species. The absolute best that could possibly be done short of true extermination is destroying the Overmind to reduce them to merely ''very'' dangerous animals. [[spoiler: Turned on its head when it turns out the Overmind [[ThanatosGambit intentionally got itself killed]] to place Kerrigan as its successor and finally relieve the Zerg of this compulsion, and on top of that they may be the ''only'' thing standing between the other races and an unknown party that will otherwise destroy all life in the galaxy -- the Overmind executed this gambit because otherwise the Zerg would destroy all other life, then be destroyed in turn by this new threat.]]
* ''Franchise/{{Halo}}'': The Human-Covenant war is mostly this, with the Covenant going to far as to [[ApocalypseHow completely destroy]] each human planet they encounter, since their Prophets have declared that humanity should be wiped out. However, there are still many Covenant members with no real ill-will against humanity, with some even wondering why the Prophets haven't already asked humanity to join the Covenant instead. This trope starts to go away once [[spoiler:the Covenant's Elites get betrayed by the Prophets (with many being forced to team up with humanity) and the Covenant religion itself is shown to be a lie]]; nowadays, while tensions remain, the majority of those left from both sides have no wish to wipe each other out, with many finding ways to even cooperate. Played thoroughly straight by anyone who has to fight [[ZombieApocalypse the Flood]].
* In ''VideoGame/PerfectDark'', [[ActionGirl Joanna]] teams up with the [[TheGreys Maians]] in the last two levels to exterminate all the [[TheReptilians Skedar fanatics]]. This is not remotely depicted as a bad thing, because they have a HiveMind and can't be reasoned with.
* The Human-Locust War in ''VideoGame/GearsOfWar'' is one of these. The Locust want to exterminate humanity so they can have the surface of Sera, and the humans want to exterminate the Locust in self-defense. The Lambent also get in on this when they show up, making it a [[MeleeATrois three-way]] GuiltFreeExterminationWar.
* The war against the Kreegan in ''VideoGame/HeroesOfMightAndMagic III: Armageddon's Blade'' becomes this after Erathia drops out. The remaining anti-Kreegan forces are well aware that the 'Devils' are a severe threat to the world (even if they aren't aware of the full scope of the threat), and finishing the war to the bitter end is really the only long-term option, while the Kreegans built the titular Armageddon's Blade to burn the world. Even before Erathia dropped out, the problems the nobles had with a campaign of extermination wasn't the extermination, but rather the cost in troops and gold.
* In ''Videogame/WingCommander'', the Confederation-Kilrathi war was this for the Kilrathi from the start, and for the humans it became so after the Kilrathi [[ISurrenderSuckers faked a desire for peace in order to build up a massive fleet that was used to completely sterilize several planets]], with Earth on the list for the same treatment before being pushed back as shown in the novel ''[[Literature/WingCommander Fleet Action]]''.
* The gameplay of the ''VideoGame/{{Warcraft}}'' games generally play this straight. To win you typically have to annihilate the enemy force down to the last peasant worker and farm and they'll do the same to you if given the chance. In-story the Alliance refused to wipe out the remaining Orcs when the war was lost, but the survivors were so dispirited that attempts to coexist with them failed utterly and they ended up left in interment camps until Thrall led an uprising.
* ''VideoGame/WorldOfWarcraft'''s quests often boil down to this. There are some specific examples in the story.
** Used in ''Cataclysm'' with the evil Black Dragon's being rendered extinct by Wrathion; apparently the only uncorrupted Black Dragon.
** ''Mists Of Pandaria'' plays this straight with the formerly neutral Zandalar tribe and the Mogu.
* Operation Final Fury in ''[[VideoGame/{{X}} X3: Terran Conflict]]'' is a military operation between [[ProudWarriorRace three]] [[HumansByAnyOtherName separate]] [[FishPeople races]] to completely wipe out a hostile race of BeePeople - the Kha'ak. The player helps out as a mercenary, and is the one to kill off the Kha'ak Hive Queen. By the time ''Albion Prelude'' takes place, the Kha'ak are totally absent - the only sign of them are their abandoned ships drifting through space. Which conveniently allows the [[LostColony Argon Federation]] to focus its resources into trying to kill off the [[HumanityIsAdvanced Earth State]], which they start by blowing up the [[RingworldPlanet Torus Aeternal]] defense station which encircles Earth's equator, causing it to [[ColonyDrop de-orbit and kill tens of millions]]. The Terrans respond in kind by obliterating any Argon ships and stations they come across. The war becomes so brutal and apocalyptic - and the [[AIIsACrapshoot Xenon fleets]], now ignored, were allowed to [[HordeOfAlienLocusts expand exponentially]] - that the Ancients shut down the [[PortalNetwork jumpgate network]], grinding the war - and [[EndOfAnAge interstellar civilization]] - to complete stop instantaneously.
* In [[http://www.huffingtonpost.co.uk/2012/06/12/man-plays-civilisation-ii_n_1589153.html?just_reloaded=1 this]] amazing game of ''VideoGame/{{Civilization}} II'' which has been running on and off for the past '''ten years''', the world has descended into a nightmarish dystopia which proves undeniably that WarIsHell. There are three main factions, the Americans, the Vikings and the Celts, who are locked into a brutal, genocidal, fight to the death and have been for the past 1,700 years. All attempts at peace or even EnemyMine situations [[ViolenceIsTheOnlyOption fail miserably]] with the AI sides betraying and attacking the player and each other scant moments after a cease-fire or agreement is signed, the constant nuclear war has [[DepopulationBomb killed 90% of the world's population]] and reduced the Earth's surface to radioactive swampland, the polar ice caps have melted 20 times so far, and large cities and improvements are a thing of the past because [[WeHaveReserves all available resources go to fueling the war effort]] and any city that does grow large is likely to be nuked.
* In ''VideoGame/GuildWars Prophecies'' this is the nature of the war between the Charr and humans. The Charr are all too willing to wipe out all three human nations on the continent and use the survivors as slaves and entertainment while the humans view the Charr as little more than dangerous animals. Even after the Shamans were overthrown, the Charr persisted in a war to drive out the remaining Ascalonians for over ''two centuries''. It took the appearance of the Elder Dragons to stop the fighting and some hardliners on both sides have decided to keep the war going.
** The Mursaat were willing to kill anyone who refused to submit to their control, resulting in an all-out war between the White Mantle and the free people of Tyria. In the end, nearly the entire Mursaat race was exterminated along with the majority of the Mantle.
* If the two [[ScaryDogmaticAliens Progenitor]] factions are present in a game of ''VideoGame/SidMeiersAlphaCentauri'', this will always be the result. Unlike the human factions, who can overlook ideological differences for pragmatic reasons such as global politics, good trade relations and technology sharing, the Progenitors have their aggression hard-coded into their AI. They will ''never'' stop fighting, and will sink every available asset into grinding the other faction into dust.
* In ''Videogame/{{Stellaris}}'', this is pretty much your only option if your galactic neighbors are a HiveMind with the [[HordeOfAlienLocusts "Devouring Swarm"]] trait, or a machine empire with the [[RobotWar "Determined Exterminator"]] trait (unless you're a machine empire yourself). Such star-nations have HardCodedHostility, limiting their diplomatic options with other races to insults, declarations of rivalry, or declarations of war. [[spoiler:The endgame crisis factions - the Unbidden, Prethoryn Scourge, or the Contingency - as well as the End of the Cycle should someone be stupid enough to make a bargain with it, are even more limited, and are simply in a state of perpetual war with everyone else.]]
** Empires with the [[AbsoluteXenophobe Fanatical Purifiers]] civic also have HardCodedHostility but other empires that conquer their planets can attempt to integrate their populations (though it is difficult).

* In ''Webcomic/StandStillStaySilent'', a PlagueZombie apocalypse has made the Nordic countries humanity's last bastion, and even said bastion has gone through a massive DepopulationBomb because of it. Humanity's remaining soldiers hence have few qualms about literally burning down PlagueZombie winter dwellings in the process of land reclamation and shooting any residents that escape the fire. On top of this, the MeatPuppet situation of plague victims means that killing the monsters they have become is a MercyKill.

* The Highbreed from ''WesternAnimation/Ben10AlienForce'' were determined to wipe out every other life form in the universe, convinced they were more "pure" than every other organism. Pretty much every other species had caught on to this, and didn't hesitate to destroy Highbreed in return. [[spoiler: Ben found a way to Play With this trope and resolve the issue: he used the Omnitrix to graft alien DNA into all the Highbreed, leaving them no longer "pure" Highbreed and removing the rationale for their Extermination War. In a sense, they ''were'' wiped out '''as Highbreed''' to resolve the conflict; they just got new lives as hybrids instead of having to die ''en masse''.]]
* ''WesternAnimation/TheDreamstone'' is an understated case. Zordrak frequently threatened to kill off more Urpney minions the longer he had to wait for the Dreamstone and his enemies to be annihilated (and early on was [[YouHaveFailedMe perfectly willing to act on that]]). Only once have members of both sides thought of [[JustEatGilligan joining forces to get him out of both their hair]], otherwise they both tend to think the other is quite cruel for not accepting the brunt of his wrath for their sake. Later episodes tried to underplay the Urpneys' lethal stakes, likely so the heroes could look more morally superior.

[[folder:Real Life]]

* There have been multiple conflicts in the past that are guilt free in the sense that the present day descendants of the exterminators feel no particular guilt about what happened, usually because it wasn't only war that ended their existence. The Selk'nam people of Tierra del Fuego (and the reason for the name, land of fire, due to their campfires) were genocided by bounty hunters paid by sheep farmers. The Celts of Western Europe, and their offshoot the Picts in what is now Scotland, have functionally disappeared, exterminated as much by war as the effects of the rise of Christianity and absorption of Celts into nearby cultures.
* Some of the wars waged by the Romans were seen as this, this in practice, or both. The most famous example is the Third Punic War against Carthage. The conflict's end saw the city of Carthage itself razed to the ground, its entire population killed or enslaved. The Romans seemed to think that this was perfectly fair, probably because (noting it's the ''Third'' Punic War) they've had to deal with Carthage ''twice'' before, and the second time around, they had to deal with an audacious guy named Hannibal who actually gave them a few headaches. Third time around, razing the city was their way of "nuking from orbit": they wanted to be sure this time.
* In 1940, [[UsefulNotes/NazisWithGnarlyWeapons the Wehrmacht]] and the [[ThoseWackyNazis National Socialist German Workers' Party]] played this trope straight when it came to planning [[UsefulNotes/WorldWarTwo a Soviet-German War]] and explaining the reasons for it to their soldiers and citizens. They were in wholehearted agreement that the USSR was going to try to destroy them at some point and that their 'preventative war' against the USSR had to be a ''Vernichtungskrieg'' ('War of Annihilation') in which the power of 'Judeo-Bolshevism' would be destroyed forever via the complete extermination of the USSR's peoples.[[note]] Albeit only eventually. The initial plans (Generalplan Ost) called for an immediate population reduction of 40 million, just 1/4 of the population of the areas to be occupied (and 1/5 of the total, Soviet Asia having another 40 million). The rest were to be retained as slaves until they could no longer serve their masters. NSDAP ideology made it unthinkable for the survivors ''not'' to be enslaved and then exterminated at some point.[[/note]] When it became clear that Germany was losing, most Germans expected that the USSR would exterminate them back and fought all the harder as a result.
* Anybody who's ever had to deal with a bug or rodent infestation in their home or workplace has fought one of these, or at least tried to. Exterminators make a career out of this, gassing and poisoning pests by the thousands.
** This trope is Downplayed when the infestation is of something that is unlikely to cause someone major problems, as such "wars" tend to be extremely one-sided, since while an exterminator can kill bugs by the hundreds, there are relatively few bugs that can cause a fatality in any way but a freak accident.
* Any time humanity has eradicated an infectious disease.
** Though, of course, as of 2016, this has only happened twice: smallpox and rinderpest. We're currently trying to eradicate three others: [[https://en.wikipedia.org/wiki/Poliomyelitis_eradication polio is very nearly down for the count]], with annual wild-type cases down to the double digits and (as of 2017) being confined to Afghanistan and Pakistan, and [[https://en.wikipedia.org/wiki/Dracunculiasis#Eradication_program dracunculiasis (guinea worm disease) is likewise down to double-digit annual caseloads]] spread out over four countries in the Sahel zone of Africa, while [[https://en.wikipedia.org/wiki/Yaws yaws]] is still endemic in several countries but is being targeted for elimination.
* While actual wars are very rarely this in RealLife, it's often played straight in propaganda during wars, in order to keep the war going by drumming up public support. This is known to happen even if relations between the countries were fine before the war started: the UsefulNotes/FirstWorldWar is perhaps the TropeCodifier, as only after then did there start to be serious backlash against this.