"Guardians of the Galaxy" may refer to:

* ''ComicBook/GuardiansOfTheGalaxy'': The Creator/MarvelComics series.
* ''Film/GuardiansOfTheGalaxy'': The 2014 movie adaptation of the comic book.
* ''WesternAnimation/GuardiansOfTheGalaxy'': The upcoming 2015 animated adaption of the movie.
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