Most stories that are in a school setting feature a [[AlphaBitch mean, but insanely popular girl]] and a [[CoolLoser likeable, but considerably less popular girl]] who will invariably be at odds with each other. In the worst case scenario, each will routinely be at the other's throat. (That may form a great deal of the story's plotline.) Even in the best case, these characters will rarely be able to share a civil conversation. Either way, it's very unlikely that these two characters will ever be friends.

Except that, in some stories, they ''were'' friends at one point, but some kind of rift came between them and split them apart. Their friendship may stretch back all the way to the first day of kindergarten, but now it's history...bitter history. Common causes of the rift are a romantic entanglement in which one of them ended up with a boy the other had a crush on or the simple fact that the AlphaBitch outgrew her awkwardness and became popular and the CoolLoser didn't. In stories of this type, don't be surprised if the AlphaBitch and the Cool Loser eventually start on the path to being [[LovableAlphaBitch friends again]]. At the very least, the Cool Loser may express the sentiment that popularity has changed her friend and that she wishes things could be the way they were before.

Subtrope of WeUsedToBeFriends.



[[folder:Anime and Manga]]
* [[spoiler: AlphaBitch Aya and {{Yandere}} Mariko]] in the anime of ''Manga/OniisamaE''. More exactly: [[spoiler: Aya threw Mariko under the bus during a school competition while in junior high]], and now in highschool they hate each other. [[spoiler: Though they make amends...but not before Aya presses Mariko's BerserkButton ''to the bottom'' (which gets her kicked outta the Sorority and almost expulsed from Seiran) and later is subjected to BreakTheHaughty.]]
* In ''{{Naruto}}'', back when they were in the Ninja Academy, Ino was the most popular girl, and Sakura was shy and had no friends. Ino befriended her and helped her gain more confidence, but Sakura ended their friendship when she found out they both had crushes on Sasuke ''and'' this made her realize that she was in danger to eternally be under Ino's shadow. After they fight one another, they end up as VitriolicBestBuds for a time, before largely setting the rivalry aside after the TimeSkip when Sakura teaches Ino how to be TheMedic.
** Certain flashbacks (some canon and some filler) actually shows Naruto being friends with Shikamaru, Chouji, Kiba (all the former), and even Sakura and Ino (both the latter.
* In ''Manga/MyHeroAcademia,'' protagonist [[NerdActionHero Izuku]] was childhood friends with [[HeroWithAnFInGood Bakugo]], who would become his middle school [[TheBully bully]] and high school [[TheRival rival]]. Once Bakugo got [[HandBlast a powerful Quirk]] he began to look down on Izuku, who was a MuggleBornOfMages, and gets ''[[BerserkButton insanely]]'' [[HairTriggerTemper mad]] at any implication that Izuku thinks that they can be equals. Interestingly, Izuku never stopped admiring Bakugo's [[{{Determinator}} ambition]], nor did he ever stop calling him by the AffectionateNickname "Kacchan"[[note]]from Bakugo's given name, Katsuki[[/note]].

* [[AlphaBitch Stacey]] and [[CoolLoser Anna]] in the 2003 version of ''Film/FreakyFriday2003''. Notably, Tess thinks this can be solved with a [[EpiphanyTherapy heartfelt speech]], which blows up in her/Anna's face almost immediately.
* Janis to Regina in ''Film/MeanGirls''. In an interesting variation of the trope, Janis proves [[NotSoDifferent to be almost as bad as Regina.]]
* ''Film/{{Heathers}}'':
** Played straight, only with the old friend being a minor character. It turns out that Heather D., who is becoming the new head of the school's food chain, was once best friends with the unpopular, unattractive, and obese Martha "Dumptruck" Dunnstock. Heather D. is so ashamed of this that when she finds out J.D. has photographs of the two of them playing together, she pays him to get rid of them.
** Averted with Veronica and her best friend Betty. They are still friends but don't get to hang out as often due to Veronica being seized by the popular crowd. They reunite by the end when Veronica severs ties with the Heathers (Whom she didn't really like to begin with).
* The title character from ''Film/JennifersBody'' is the AlphaBitch; the narrator is her best friend and a HollywoodNerd . The entire film is about the main character escaping from this relationship.
* The original version of ''Disney/OneHundredAndOneDalmatians'' invokes this, although the characters have long since finished school: "Oh, must be Cruella, your dearly devoted old schoolmate."
* Amy to Dylan in ''Film/GeekCharming''...though she still considers Dylan a friend regardless and wishes for her to get over her [[AlphaBitch Alpha Bitch-iness]] so they can hang out together again, which happens in the end.
* Inverted in ''Film/ThirteenGoingOnThirty'' where the AlphaBitch is Jenna's best friend when she's 30 but they didn't get along in school. Subverted, when they aren't really friends at all.
* Chris Otter and Katie Twentybreed in "The Mysterious Alpha Bitch" (2013). They were friends as little girls, but one day someone killed the Katie's dog while Chris has custody and Katie blamed Chris.

* Chantal Simmons in ''The Geek Girl's Guide to Cheerleading''. She used to be friends with the heroine when they attended the same dance school, but Chantal became a cheerleader and the heroine became a nerd. This marked the end of their friendship.
* Samantha Deveraux in Marlene Perez's ''Literature/DeadIs'' series. In the first book, ''Dead Is the New Black'', the heroine mentions that she and Samantha were friends until they had a falling out. By the beginning of the second book, ''Dead Is a State of Mind'', they're working on becoming friends again. It helps that Samantha's bitchiness is mostly an act.
* Subverted by Aravis and Lasaraleen from ''Literature/TheHorseAndHisBoy''. They weren't the chummiest of friends, but [[TomboyAndGirlyGirl they did have a history together]] and Lasaraleen is more of a BrainlessBeauty than a true AlphaBitch since, for all her snobbishness and irresponsability, she does care for Aravis in her own way.
* In ''Amelia'', a variation happens where Amelia and Lucinda are best friends at the start but once Amelia's family loses their money, Lucinda acts more like an AlphaBitch and looks down on Amelia for being poor.
* Sam from ''Literature/AllAmericanGirl'' used to be childhood friends with AlphaBitch Kris Parks before temporarily living abroad. [[spoiler: Fortunatelly, Sam's sister Lucy happens to be more popular than Kris and can help with standing up to Parks when situation requires.]]
* In ''Literature/BeforeIFall'', [[spoiler: Lindsay and Juliet "Psycho" Sykes used to be friends, before Juliet took the blame for Lindsay's bed-wetting.]]
** Kent [=McFuller=] used to be [[TheProtagonist Sam's]] best friend and was even her first kiss. Then he became a freak, as Sam puts it.
* Not directly true with Janine and Candayce in ''{{Literature/Dinoverse}}'', but when Janine was a new student in a new, handmade dress, Candayce made a show of acting nice to her before ruining it. Later Candayce went to the effort of turning Janine's best friend against her, getting her to join a more popular clique after publicly assaulting and denouncing Janine. Over the course of the book they slide from bitter enemies to something still loaded with sniping, but friendlier.

[[folder:Live-Action TV]]
* Kate and the titular heroine of ''Series/LizzieMcGuire''. They used to be best friends until Kate become popular because she developed early in regards to puberty.
** Something of the sort happened when Kate got dethroned by Claire due to Kate breaking her arm.
** If TheMovie is any regards, there are hints they'll be friends onc e mroe when they grow up.
* In ''Series/BuffyTheVampireSlayer'', it was established one time that Cordelia, Xander and Willow all used to hang out together when they were preteens. Cordelia becomes more friendly with the Scoobies once she starts dating Xander, but then goes through another phase of being their "ex-friend" after he cheats on her with Willow. They apparently make up eventually, at least to the extent that Cordelia calls Willow in an episode of ''Series/{{Angel}}''', though calling them outright ''friends'' might be pushing it since Cordelia only found out Willow was a lesbian after she had been out of the closet for a whole year.
* Abigail Armstrong and Kat Karamakov from ''Series/DanceAcademy'' at first appear to be a subversion of this trope, as it seems to viewpoint character Tara that ambitious, unlikable, dedicated (and unpopular) Abigail ditched gregarious, pleasant, careless (and popular) Kat as a friend after she stopped taking ballet seriously - but in fact the trope proves to be played rather straighter, as the truth is that when Kat (the daughter of a prima ballerina and a choreographer) started being unhappy with her ballet-focused life, she decided her former best friend Abigail was a boring 'Betty Bunhead' and ditched her.

[[folder:Video Games]]
* ''VideoGame/TheSandMan'': Part of the reason Sophie doesn't stand up to Regan's constant harassment is because she remembers being friends when they were younger.

* The now-ended webcomic ''Webcomic/AsIf'' had Hunter and Sandy, who used to be [=BFFs=] in junior high. (Hunter even says Sandy used to throw amazing TabletopGame/{{Risk}} parties). But as time went on, Sandy got into makeup and boys, and Hunter...[[{{Tomboy}} well, let's]] [[TheDaria just say]] [[InformedLoner she didn't]].
* ''Webcomic/PennyAndAggie'': Apparently Helen used to be friends with Penny and is ''still'' bitter.
* Sayuri Morita of ''Webcomic/RedString'' used to be friends with Miharu and Reika in middle school, but after only Miharu and Reika were chosen to appear on a sidewalk TV show, she became obsessed with being popular and pretty much declared them her enemies. Flash-forward to high school where she's given herself a new image, gained a clique, and keeps making Miharu, Reika, and Fuuko's lives miserable.

[[folder:Web Original]]
* In ''Literature/SailorNothing,'' Aki has a falling-out with Ami after the former's [[EnemyWithout yamiko]] ruins her reputation. It's actually the best thing that could have happened to Aki, who finally sees how shallow her life had been.
* ''Literature/{{Worm}}'': Until the summer before they started high school, Taylor's best friend was Emma Barnes. After that summer, Emma was instead the leader of the trio of [[TheBully bullies]] responsible for making her high school life pure hell.
* ''Literature/FunnyBusiness'': Not only did Isabella use to be the best friend of the protagonist Jeannette, but [[spoiler: she used to be a ShrinkingViolet too shy to interact with anybody else]]. However, even then, she had always been jealous of Jeannette's RealityWarper powers, and after the latter uses them to help her overcome her shyness, she effortlessly integrates into the popular crowd and becomes a bully, with an advantage over the others in that she knows what makes the protagonist tick.

[[folder:Western Animation]]
* Sharon Spitz and [[AlphaBitch Nina Harper]] from ''WesternAnimation/{{Braceface}}''--they were best friends as little kids, but Nina ended their friendship when she saw that someone had decapitated all of her beloved fashion dolls, and blamed Sharon for it (despite having no evidence to prove that Sharon was the culprit)--Nina's parents and Sharon's dad assume that the girls are still friends. Early in the third season, it turns out that a mean cousin of Nina's was the true culprit, and Nina, realizing the truth (and the fact that she wasted so many years being mean to Sharon for nothing), she tries (but ultimately fails at) reconciling with her.
** However, over the course of the series, it's implied that Sharon and Nina will eventually become friends again--their relationship just needs a little more time to regrow, and they probably won't be as close as they were when they were little kids.
* On ''WesternAnimation/TheSpectacularSpiderMan,'' Peter and [[JerkJock Flash]] were friends when they were in preschool, and they still live just around the corner from each other. [[AmazinglyEmbarrassingParents Flash's mom]] [[ParentalObliviousness assumes]] that her son and Peter are still friends, and even sent Peter an invitation to Flash's birthday party. It also turns out that Peter was behind Flash's nickname originally (and it was for more hilarious reasons than expected).
* ''WesternAnimation/TinyToonAdventures'': The episode that parodies ''Film/CitizenKane'' shows Buster Bunny and Montana Max used to be friends until Max's parents [[RagsToRiches won the lottery]].
* Mimi Morton and Sincerity Traverse from What About Mimi.
* ''{{WesternAnimation/Sixteen}}'': Caitlin to Tricia. After Caitlin maxed out her credit card and her parents forced her to get a job to pay it back, Tricia ended her friendship with Caitlin after seeing the uniform she was forced to wear at her new job, essentially saying that she can't be seen with someone who has to work for a living.