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- An A-1 Steak Sauce commercial depicted a man using one of these centrifuges to get the absolute last drop of sauce out of the bottle. "Yeah, it's that important."
- Happens in a Buck Danny comic where the main characters take part in the X-15 flying program. Sonny rather insistently asks the pretty doctor assessing them for a date, prompting said doctor to ask the centrifuge operator to crank up the test Sonny is about to be subjected to. Sonny spends the test yelling and collapses upon exiting the centrifuge.
- Moonraker. While on a tour of Drax' aerospace facility James Bond was put in such a machine by Holly Goodhead and given a spin. While he was undergoing this, Holly was called away and Drax's henchman Chang took over, turning the dial up and subjecting Bond to multiple gravities of force. Just before falling unconscious, Bond used one of his gadgets to shoot the control panel and turn the machine off.
- In a rare example of being used for its intended purpose, the centrifuge appears in The Right Stuff as part of astronaut training.
- In the film Muppets from Space, Rizzo spins in the centrifuge in C.O.V.N.E.T. while enduring science experiments.
- Not related to training, but on The Iron Giant, Hogarth and the Giant are playing test pilot with an old car. The Giant spins the car a little faster than Hogarth imagined.
- The centrifuge is used in the film Spies Like Us. The heroes then go to lunch looking and sounding weird.
- The movie Rocket Man (about a manned mission to Mars) has one. When the Idiot Hero is riding it, he is so unaffected by the forces that the supervisors keep raising the speed, causing the seat to detach itself and go plowing through several corridors.
- Moscow — Cassiopeia had these.
- The infamous "Tequila" scene from The Sandlot involves a bunch of kids trying chewing tobacco to emulate their baseball idols, and then getting onto a fast spinning carnival ride. Vomit ensues.
- The over-the-top amusement park rides in the opening scene of Spy Kids 2 are mainly of this type.
- In Godzilla vs. Mechagodzilla II, Kazama Aoki is put in a similar device while training to pilot Mechagodzilla. The chair spins in place instead of around an object.
- In the Moonbeam series of picture books about a chimp at NASA, there is a scene where Moonbeam is put in one these machines, and spends the next few pages stumbling around bumping into things.
- In the Discworld illustrated story The Last Hero, Leonard straps Rincewind into a Clock Punk centrifuge machine (the diagram of which looks a lot like the Vitruvian Man) before their dragon-powered spaceflight, on the basis that the only way to train for the unexpected is with unexpected training. Before his experience in the centrifuge, Rincewind protests that they're heading for certain death, which you don't need any training for; afterwards he says that if you did, that would be it.
- Averted in Space Cadet where zero-G training is done via a gravity-drop tower built against a 2000-foot high cliff. On reaching the bottom, you're accelerated up to the top and start over at a faster drop rate.
Live Action TV
- Used in Battlestar Galactica to simulate difficult targeting conditions for Viper pilots.
- Kerbal Space Program supplies both the page image (via Fan-Art) and now, in the official trailer for release .21, an animated CGI version.
- In Sam & Max Hit the Road, the Cone Of Tragedy at the Cushman Bros. Carnival spins around at insane speeds, as befitting its name. If you ride it, you will lose all your stuff and have to get it back from the Lost and Found... along with an item you need to progress in the game.
- Adventure Time, "Five Short Graybles": Princess Bubblegum puts a cow into a centrifuge to make the perfect block of cheese.
- BenMummy and a Werewolf-esque alien fight next to one of these in an episode of Ben10.
- The Disneyland show episode "Man in Space", which was made in 1955, had a section on how astronauts would be trained, including being put on a centerfuge. Seeing how far the show predates the actual space program, it's remarkable how far ahead the scientists involved (who were consultants on the episode) were preparing.
- The Simpsons: Homer & Barney each get put in one of these when they're being trained as astronauts. Homer in particular briefly turns into Popeye due to the G's.
- My Little Pony: Friendship Is Magic: In the episode Wonderbolts Academy, the Dizzytron is an obvious parody of this trope. It's also an unusual usage, as it's designed to launch pegasi into the air after it's done spinning—the pegasi are then timed on how quickly they can recover and land safely.
- Pinky and the Brain were put into a one in the episode "Where No Mouse Has Gone Before".
- One episode of Arthur had an amusement park ride called the Hurl-a-Whirl that did pretty much Exactly What It Says on the Tin: basically a dumbbell-type centrifuge, except the car itself spun perpendicular to the arm as well. The individual cars actually had a dial to increase the ride speed, with the highest setting being "Liquefy".
- An episode of Rugrats showed Angelica getting on something like this at a carnival. It turns out to be a very high speed one, and when Stu tries to get the operator to shut it off, he misunderstands and turns it Up to Eleven. When Angelica gets off, and Didi asks if she's alright, she responds, "I think so, Uncle Stu."
- Happen to Chip and Dale in Chip 'n Dale Rescue Rangers with Gadget and Jack at the controls. They are Squashed Flat when the centrifuge finally stops.
- Tiny Toon Adventures: Hampton's family go to Epcot and go on a centrifuge-like ride (this episode debuting years before Epcot even had such a ride); Hilarity Ensues.
- Briefly shown in Barbie And The Rockers Out Of This World. Barbie, whose Mary Sue-ness has been ramped Up to Eleven (to the point where she is able to afford the bajillions needed to paint a space shuttle pink—Unlike Life in the Dreamhouse, this is not a parody), is shown having used one, but showing perfect composure and with her massive perm still intact.
- Inspector Gadget gets the centrifuge treatment in "Launch Time".