->'''Howard''': You ready to talk about it?\\
'''Sheldon''': I'm not nearly drunk enough. ''(takes a sip of beer)'' Okay.
-->-- ''Series/TheBigBangTheory'', "The Mommy Observation"

People you should ''never, ever'' offer a drink to. As soon as they even taste a drop of alcohol, they either pass out (putting you in danger in case that person should ''really'' be awake) or go off the deep end. It rarely gets as far as endless vomiting or a near death experience, or anything else that usually happens after alcohol poisoning, because this is primarily a comedy trope, though it can be used in a dramatic work as well if the person in question is a particularly abusive mean drunk or turns into a disgusting lecherous creep.

This trope is extremely common, and is most often used for comedic effect. If you need to wake him up fast, you'll need a HideousHangoverCure.

May overlap with KissingUnderTheInfluence, IntoxicationEnsues, DrunkenMaster, LampshadeWearing. Polar opposite of NeverGetsDrunk.

If instead the character gets intoxicated from something that's not alcoholic at all, they're DrunkOnMilk.

Depending on how serious the fiction is trying to be, it can very well be TruthInTelevision, although it's more common and more fun to [[IntoxicationEnsues exaggerate it past all semblance of realism]]



[[folder:Anime & Manga]]
* Even though Dr. Hell from ''Anime/MazingerZ'' tends to enjoy AGlassOfChianti now and then, he gets tipsy easily. In the last episodes of one of the manga continuities, he barely could stand upright after one glass. On the other hand, his minions (Baron Ashura, Count Brocken, Viscount Pygman) show a bigger tolerance to alcohol.
* Doctor Clive and Haré (though he is a kid) from ''Anime/HareGuu'' both get drunk from one sip of beer. The Doctor becomes childish while Haré is one mean drunk.
* England in ''Manga/AxisPowersHetalia'' (English dub version). After one drink, he's passed out on the bar, wondering whether he's Catholic or Protestant, declaring himself "The United Bloody Kingdom" and announcing that he can "...[[{{Malaproper}} hild his locker]]" better than America, whining/crying over America not accepting his friendship because of their shared hatred of France, and bawling over how the friendship refusal is "total bollocks!" [[spoiler:The next day, England is under a green blanket, shivering and wondering why the light won't shut up]].
-->'''Bartender:''' Is he okay?\\
'''America:''' Naw, he always gets like this when he's drinking.\\
'''England:''' [[IllTellYouWhenIveHadEnough YOU DON'T KNOW ME!]]
** Possibly subverted, because there was a scene cut and it is never stated how much he drank.
** Also justified, considering the size of Britain.
*** Which in contrast, Russia, the largest country in the world is [[NeverGetsDrunk never seen drunk]] despite [[VodkaDrunkenski his love of vodka]].
** Spain becomes "very sentimental" when he drinks, according to WordOfGod.
** [[PerpetualSmiler Denmark]] is falling off his chair drunk in the Nordic Five Drama CD, to the point that he has to be taken home by his [[OddFriendship best friend]] [[DeadpanSnarker Norway]]. Ironic, considering he's the [[TheAlcoholic heaviest drinker in Northern Europe]], and Norway calls him a drunk in the same CD.
* Sora Wakanae, from the manga ''Manga/FamilyCompo'', falls asleep after drinking one glass of beer.
* Negi of ''Manga/MahouSenseiNegima'' got drunk from one cup of amazake, which is a sweeter, ''low-alcoholic'' version of traditional sake. He is ten years old, but still...
* ''Anime/DragonBallZ'':
** As of ''Anime/DragonBallZBattleOfGods'', Son Gohan is officially this trope.
** This however, was foreshadowed all the way back on the first movie ''Dead Zone'', where upon eating one of the apples in Garlick Jr's palace (said to be alcoholic), he went all-out tripping balls.
* In ''Manga/MythicalDetectiveLokiRagnarok'', Narugami is revealed to be like this, when he's forced to pose as the bride of a shinto wedding (long story) and drinks from the ritual cup of sake -- instantly becoming roaring drunk, which is kinda' odd considering that he's an incarnation of Thor, who was famous for his alcohol-capacity. Of course, Thor was also famous for being a roaring drunk--these two attributes are not necessarily incompatible.
* [[ShrinkingViolet Shinobu]] from ''Manga/LoveHina'' gets wasted after a sip of white wine. Justified, as she's 13 years old.
* Rock Lee from ''Manga/{{Naruto}}'' gets drunk (and goes into [[DrunkenMaster kick-ass mode]]) from just one sip of alcohol.
* In ''Manga/{{Mahoraba}}'', one of Kozue's personalities (ironically the tough one) couldn't drink anything but very weak wine. The anime [[CharacterExaggeration ups this]] to getting knock-out drunk from even ''smelling'' beer.
* Captain Shuusuke Amagai from the ''Manga/{{Bleach}}'' anime gets utterly drunk from a single cup (or sip?) of sake. This becomes a problem (and a RunningGag) due to his friendship with Captain Kyoraku, who ''always'' has sake during their conversations. On one occasion, he became drunk after smelling sake. He claims he has also become drunk from eating food that is ''flavored'' like sake. And you know you're in trouble when smelling sake [[http://www.youtube.com/watch?v=6QyoSOuyTiU leads to this.]] One of the funniest instances of this for the Captain is in his debut episode, where he takes a drink and passes out. Immediately afterward, his squad is sent on an emergency mission. When his squad is about to be wiped out, he shows up, saves the day in a spectacularly badass way, makes an insightful remark, and promptly passes out, still drunk off his ass.
* In ''LightNovel/HaruhiSuzumiya'', [[{{Moe}} Mikuru]] already gets drunk after one glass of whatsoever. She actually got intoxicated with tequila by [[MagnificentBastard Haruhi]] and [[GenkiGirl Tsuruya]] for the Brigade-movie (and Kyon didn't like it ''at all''). [[BadassBookworm Yuki]] [[NeverGetsDrunk can gulp down barrels without being affected at all]] (probably because she's an ArtificialHuman). Haruhi herself is a [[LadyDrunk helpless drunkard]], gulping down one bottle of wine after another. ''Even Kyon'', who snarked about it before, eventually gets totally boozy in the novel-version of "Remote Island Syndrome (although we're not told how much he can handle, he says it's a lot, or how he acted, although it's mentioned he did have trouble walking)." [[CrowningMomentOfFunny It's hilarious]]! The anime aversion actually plays it ''up'', since rather than getting drunk of tequila Mikuru gets drunk off ''amazake'' which has a much lower alcohol content, to the point where it doesn't even bother the censors since [[{{Bowdlerize}} its illegal to show minors consuming alcohol on Japanese TV]] (which also explains the changes in Remote Island Syndrome).
* Van in ''Anime/GunXSword'' is knocked out by a single swig of tequila and rendered helpless by a single glass of wine (which he mistook for something less harmful). He's quite aware of this; his trademark DrinkOrder is milk.
* Train from ''Manga/BlackCat'' cannot hold his liquor. He's shown having a HUGE hangover soon after drinking a small bottle of wine.
* Sagara Sōsuke from ''LightNovel/FullMetalPanic''. Even though he's a soldier, he evidently almost never drinks, and therefore has very little endurance for the stuff. In one chapter of the manga, he's shown taking a sip from a small cup of amazake (a drink that has very low alcohol content), and promptly gets dead drunk, complete with the fever and loss of strength. Kaname even comes out and tells him, "you '''really''' can't hold your liquor." And even after passing out and coming to, he's ''still'' drunk, with Kaname lamenting that there's a limit to how much of a lightweight people can be. Later in the novels, he literally Can't Hold His Liquor, due to [[spoiler:debilitating internal injuries courtesy of a rifle round that relieved him of a portion of his liver]] among other things.
** Bonus points that Sōsuke was raised as a Muslim in Afghanistan, which Islam forbids followers to drink alcohol; which may explain his low alcohol tolerance. Well at least ''some'' Islamic values, he isn't really that religious when compared the folks who raised him. Late into season 2 of the anime, Sōsuke, [[HeroicBSOD having hit rock bottom]], spent most of an episode wandering around Hong Kong with an unopened bottle of brandy. When he finally does take a swig, he promptly spits it out and tosses the bottle in the trash, wondering aloud what people see in the stuff.
* Lilica from ''Anime/BurnUp Scramble'' becomes intoxicated from even small amounts of alcohol, which exacerbates her CuteClumsyGirl tendencies, as well as bringing out the LesYay for Rio.
* Almost everyone gets sloshed (apparently on one glass of wine) in [[CrowningMomentOfFunny episode 20]] of ''Manga/PandoraHearts'', but Gilbert runs the gamut from misaimed belligerence to sloppy begging to a cute but slightly disturbing reversion to childhood. Then he passes out.
* Tsukuyo in ''Manga/{{Gintama}}'' brutalizes Gintoki (and later Shinpachi and Kagura, but mostly Gintoki) after just a small amount of [[strike:sake]] liquor-filled chocolate.
* Marron in ''Manga/SorcererHunters'' in both the manga and OAV incarnations; in the former he passes out after one drink but in the latter the results are more epic.
* Usagi from ''Anime/SailorMoon'', being a 14-year-old girl, can't hold liquor and HilarityEnsues [[https://www.youtube.com/watch?v=KT23P2fen4U when she is given a glass.]]
* Fai D Fluorite from ''Manga/TsubasaReservoirChronicle'' is shown to be both this and NeverGetsDrunk in different worlds.
* In ''[[Manga/SgtFrog Keroro Gunsou]]'', Corporal Giroro passes out from just a few drops of alcohol.
* Aoi in ''Manga/AiYoriAoshi'' gets near passing out from three beers. Possibly justified in that she was highly sheltered growing up and probably had no exposure.
* ''Manga/HidamariSketch'': For Yuno and Miyako's welcoming party, Sae and Hiro buy food and drink. Hiro inadvertently buys alcohol. At the party, the two sophomores get drunk on one glass. While Miyako's antics are pretty normal for her, the bright redness of her face tells the tale. Yuno starts talking about the color of goldfish and the sun, then passes out and is taken to sleep it off (talking in her sleep).
* In ''Manga/DGrayMan'', Allen Walker once got drunk by eating alcoholic chocolates. There's a ''reason'' he's forbidden from touching alcohol. According to the Kuro no Bansenkai Drama CD, he gets vicious when drunk and trashed a restaurant without even remembering it.
* Kinoshita from ''Manga/YakitateJapan'' apparently can't hold his liquor; he gets UnsuspectinglySoused from a single slice of Kawachi's ''sake'' bread, and Mr. Matsuhiro remarks "This guy could get drunk just from the smell of alcohol!"
* In the ''Anime/TenchiMuyo'' manga, Sasami discovers some of Katsuhito's sake by mistake, drinks one cup and promptly passes out. Granted, she's a ''kid'', but still.
* In the ''[[Anime/TheVisionOfEscaflowne Escaflowne]]'' anime, Hitomi is at a dinner party, but she isn't used to the liquor on Gaea (or indeed, alcohol in general, given her age), so she proceeds to get ''very'' drunk on the pink wine or spirit that was given to her.
-->'''Hitomi:''' (''inner thoughts upon hearing about Millerna's engagement'') [[CrowningMomentOfFunny Allen is avaliaaaaable... HIC!]]
* Hibari of ''Manga/KatekyoHitmanReborn''. He is known not to handle alcohol well.
* Zebra of ''Manga/{{Toriko}}'' is one of the biggest badasses alive in a WorldOfBadass, but he can't handle alcohol. His favorite beverage is cola (then again, cola in the world of Toriko can be really, ''really'' good).
* Throughout ''Anime/PumpkinScissors'', Alice refuses to drink alcohol under any circumstances. In the final episode, when Oland gives a speech about protecting her, she responds by giving him the opportunity--she drinks half a glass of wine and immediately passes out, falling into his arms.
* Kurama from ''Manga/KamisamaKiss'' has a very low alcohol tolerance, which is in direct contrast to his brother [[NeverGetsDrunk Jirou.]]
* Both Lucy and Saya from ''Manga/ServantXService'' has low tolerance of alcohol. Strange, their relationships with a male member of the cast were both cemented in such circumstances, with Yutaka and Jyoji doing {{Bridal Carr|y}}ies on them, respectively.
* Coo the {{Kappa}} from ''Anime/SummerDaysWithCoo'' gets drunk very easily if you pour alcohol onto the plate on his head.
* Subverted in ''Manga/ICantUnderstandWhatMyHusbandIsSaying''. Kaoru doesn't get drunk easily. But when she gets drunk, she gets DRUNK.
* ''Manga/TokyoGhoul'' has several characters that cannot hold their liquor.
** In a CrowningMomentOfFunny, Akira and Takizawa both turn out to be light weights and get easily plastered. Amon ends up caught in the middle of their drunken bickering, much to his growing horror.
** Shinohara mentions wanting to have a drink with his partner, Juuzou. (Amon recalls that he's an infamous light-weight that once beat up [[TheJuggernaut twenty]] of his coworkers when he got drunk.)
** An omake suggests that a single sip causes [[TheQuietOne Yomo]] to ramble uncontrollably and then pass out.
* At the start of LightNovel/CatPlanetCuties, Kio takes one sip of beer and passes out. He [[LampshadeHanging notes what a lightweight he is]] on his way down.
* Played with in ''Manga/AhMyGoddess''; Belldandy can take in liquor like water, but give her even a sip of cola and she'll be completely hammered. Since she is a powerful goddess, this gets problematic.
* Despite being a Valkyrie, Rossweisse from ''LightNovel/HighSchoolDXD'' really can't handle her drink. One cup of sake has her slurring out an angry rant, a second gets her helplessly snockered, and the next day she's still sporting a brutal, dexterity-killing, [[VomitDiscretionShot nauseating]] hangover.
* ''Anime/DivergenceEve'': The girls go out on leave in "Specular". At a nightclub Luxandra drinks one martini and immediately passes out.
* In ''Manga/Brave10'', Kamanosuke and Isanami get real drunk real fast during Jinpachi's drinking challenge. Kamanosuke even becomes flushed from the first drop that lands on him.
* Yun of ''Manga/NewGame'' doesn't handle alcohol very well. At Aoba's welcoming party, she passes out near the very start.
* Suzu from ''Manga/SeitokaiYakuindomo'' starts getting tipsy just from the smell of Dejima drinking beer. Justified due to how small she is.

[[folder:Comic Books]]
* There was once a very quiet, long-running joke about how ComicBook/SpiderMan's alcohol tolerance is probably the lowest of any major superhero in the Franchise/MarvelUniverse, after an issue where someone spiked the punch at a party and he had to fight Hobgoblin while drunk.
** His clones don't fare much better. Kaine managed to pass out after a grand total of THREE beers.
* In an ''Film/XMen'' comic book detailing the origin of movie Rogue, she gets drunk just by touching a drunk trucker.
* In ''ComicBook/{{Asterix}}'', Obelix gets drunk pretty fast, since he usually only drinks goats' milk. And a guy with SuperStrength shouldn't do that.
* In an appearance by the ComicBook/GreatLakesAvengers (they were calling themselves the Great Lakes Initiative at the time), all the superheroes in the MarvelUniverse have been inebriated by a Dionysus powered ray; Mr. Immortal, however, is the only person to succumb to ''alcohol poisoning''. Needless to say, he got better.
* Brian from ''ComicStrip/KnightsOfTheDinnerTable''. He is the reason why the Knights no longer allow alcohol at the gaming table. Any time this rule is relaxed, his behaviour quickly reminds them why it was instigated in the first place.
* In ''{{ComicBook/Violine}}'', Violine takes a swig of whiskey to prove that it is not poison, and gets immediately drunk. Justified, as she is only ten.

[[folder:Fan Works]]
* ''Fanfic/TheChildOfLove'': One beer can is all is needed to get Shinji drunk:
-->'''Shinji''':''"Yeah...sort of...before you arrived, Misato used to tease me by switching the drinks around in the fridge..." (blushing heavily:) "I once got drunk from only one can of Yebichu because of that..."''
* In ''[[https://www.fanfiction.net/s/5971480/1/Link-Mage-of-Fairy-Tail Link: Mage of Fairy Tail]]'', Link is this fullstop. A single drink can get him so plastered, he mistakes the people around him for enemies from Legend of Zelda and starts drunkenly fighting them. [[DrunkenMaster He's actually much better at fighting drunk than you would expect.]]
* ''Fanfic/{{HERZ}}'': Shinji has absolutely no alcohol tolerance. It is because he has no endurance that he does not drink, since getting drunk has gotten him in trouble more than once.
* ''Fanfic/ThousandShinji'': Shinji has no interest on alcohol, ergo he never drinks and if he does he gets hammered and passes out right away. Rei realized it when she [[spoiler:tried to get him and Asuka drunk and he got knocked out instantly.]]
* ''Fanfic/WalkingInTheShadowOfDreams'': Asuka has absolutely no endurance. Sometimes she wonders why a German woman has gone through college twice is such a light-weight.
* Lilly, in ''Series/TheWalkingDead: The Game'' fanfiction ''[[https://www.fanfiction.net/s/9826124/7/What-a-Difference What a Difference.]]'' She has one drink in her bedroom at the motel while Lee and Kenny are in Macon, and Carley is the one who has to deal with her. Lilly then decides to tell Carley drunkenly that she was raped ("had sex") by Danny St. John, which she was. Also, she tells Carley that her middle name is Maleen.
* Jonathan Crane (a.k.a. [[Franchise/{{Batman}} Scarecrow]]) in Lauralot's fic ''[[http://www.fanfiction.net/s/4679528/1/Act_Like_We_Are_Fools Act Like We Are Fools.]]'' He gets falling-down, spill-all-your-secrets drunk after one glass of whiskey. Mostly because of an adverse interaction between his antipsychotics and the alcohol, but still.
* ''Fanfic/PonyPOVSeries'':
** Twilight Sparkle gets a bout of PowerIncontinence from this; [[NoodleIncident apparently]], she ''brought her library to life'', and caused so much chaos that Ponyville had to be convinced Discord hadn't returned. And then she was hungover for ''two days'' afterwards.
** Fluttershy, and [[SharingABody by extension Fluttercruel]]. This annoys Fluttercruel because she honestly wanted to ''enjoy'' drinking. [[spoiler:Unfortunately, her getting them drunk contributed to Fluttershy's transformation into [[SuperpoweredEvilSide Nightmare Whisper]], since it made her more susceptible to depression and her already unstable mental state.]]
* [[Anime/YuGiOh5Ds Yusei]] goes from [[TheStoic stoic]] and [[OnlySaneMan smart]] to giggly and [[AlcoholInducedIdiocy oblivious]] because of this in the fanfic ''[[http://www.fanfiction.net/s/7524001/1/The-Alcoholic-Adventures-of-Team-Satisfaction The Alcoholic Adventures of Team Satisfaction]]''. The author believes Yusei to be a secret case of this:
-->'''Author:''' (''discussing the characters' [[IntoxicationEnsues drunk behaviour]]'') As for Yusei... COME ON. HE ORDERED [[DrunkOnMilk A GLASS OF MILK]] IN A BAR. HE MUST HAVE THE WORST ALCOHOL TOLERANCE EVER. Also, he doesn't seem the type to [[DrunkDriver drink 'n D-wheel]]. Doesn't fit a [[Franchise/YuGiOh YGO]] protagonist.
* Implied to be the case with Fluttershy in the ''Blog/ReadingRainbowverse''. Oddly, though, we never see her drinking... just the results.
* Strangely the case with Hefty Smurf in the ''Fanfic/EmpathTheLuckiestSmurf'' series. The drink in this case is sarsaparilla ale, and one glass of it causes him to stumble to the floor.
* In a party at the end of ''The Coalescence'' in FanFic/PokeWars, Dawn gets completely shitfaced on a very weak alcoholic drink. Justified by her young age.
* Used as TheStinger gag of ''StarWarsDownunder''. After thirty minutes of battling the forces of the evil Darth Drongo just to [[INeedAFreakingDrink get his hands on a nice cold one]], Jedi Knight Merve Bushwacker passes out after only one beer.
* ''Franchise/TheLegendOfZelda'' fanfic ''[[Fanfic/BoundDestiniesTrilogy Wisdom and Courage]]'' has Zelda getting flat-out ''plastered'' after taking only a few sips of Hylian Ale, which she drinks to [[DrowningMySorrows dull the pain of losing Impa]].
* ''Fanfic/AShadowOfTheTitans'': After [[WesternAnimation/JackieChanAdventures Jade]] [[OvernightAgeUp magically ages herself up]], she ends both getting hit by PowerIncontinence and being viewed as a threat worthy of being responded to by the WesternAnimation/JusticeLeague instead of the [[WesternAnimation/TeenTitans Titans]]. This naturally [[FreakOut frustrates her]]. Jinx's way of trying to help is to buy her a drink... and after only a few sips of Belgian Ale, Jade is half-conscious and wailing away on a karaoke machine. Jinx is dumbfounded by how quick it all was, given Jade's [[ExtremeOmnivore appetite]].
* In ''Fanfic/TheVinylAndOctaviaSeries'', Octavia gets much more intoxicated than Vinyl when she drinks, and the effects are much more obvious. To be fair, when she does get drunk it's the result of her drinking a lot of alcohol in a short time.
-->''Octavia merely stood on the same spot, and stared off into the distance. "I just vomited a lot of stuff, Vinyl..." she said weakly.''
* ''Fanfic/{{Bait and Switch|STO}}'': Offscreen, Lieutenant K'lak, a Klingon sniper in the USS ''Bajor's'' security department, gets into a DrinkingContest with one of his opposite numbers from a Klingon ship. Both of them passed out after four shots of Romulan ale, and this from a species that drinks bloodwine, a liquor with twice the potency of whiskey, by the tankard. (In fairness, [[GargleBlaster pretty much everyone who isn't a Romulan has trouble with Romulan ale]].)
* ''Fanfic/FrozenWight:'' Fritz starts an [[IncestSubtext Elsanna]] rumor when he gets drunk.
* In ''Fanfic/MareGenius'', Fluttershy gets completely wasted and ends up singing [[Literature/{{Discworld}} The Hedgehog Song]] after just ''sniffing'' the jug that Applejack had brought to the wedding reception. The jug contained a GargleBlaster, but still...
* Oddly Peach and Daisy are this in ''Webcomic/The3LittlePrincesses'' despite having played their DrinkingGame previously. Rosalina handles Whacka Juice quite well despite never having drank in her life.
* Alcohol is one Cress LaVeda's weakness from Tales of Faith. The moment she even takes a whiff of this, Cress will act like a complete short-tempered drunk. Unless you prepared a bottle of plain water, prepare to be violently attacked by Cress.

[[folder:Films -- Animation]]
* Portly and the chimney sweep from ''WesternAnimation/TheWillowsInWinter1996'' both get hammered off small amounts of alcohol. Toad is an aversion since he drinks a whole bottle and is only a bit tipsy by the end.

[[folder:Films -- Live-Action]]
* In ''Film/BackToTheFuturePartIII'', it turns out that Doc Brown really can't hold his liquor -- he passes out after drinking a single shot of whiskey. And before passing out from drinking said glass of whiskey, he manages to get plastered just by ''holding it under his nose''. Ironically in the script, he actually ''can'' hold his liquor, and then passed out as Marty comes to get him.
* Kim Basinger's character in ''Film/BlindDate'' had an allergy to alcohol that made her as drunk as if she'd had two six packs in mere minutes. She ate two chocolates that had alcohol injected and was literally swinging off the chandelier.
* A single sip of Scotch puts Creator/WoodyAllen's character in ''Film/PlayItAgainSam'' in a cartoonish flailing fit and a dead faint -- still, he tries to impress a date that he's a suave drinker, casually telling her "I've gotta cut down, I'm up to a quart a day."
* Lampshaded in ''Film/TheBrothersGrimm'':
-->'''Will:''' He can't hold his ale!\\
'''Jacob:''' I can't hold me ale!
* It's {{justified}} in ''Film/MadchenInUniform'' as Manuela is only fourteen years old. This trope is PlayedForDrama because she confesses something she shouldn't while drunk on punch after a SchoolPlay.
* Jeff from Creator/AlfredHitchcock's ''Film/{{Mr And Mrs Smith|1941}}'' is completely unaffected by one drink, but immediately crosses into Can't Hold His Liquor territory after two.
* Often a gag on various ''Film/TheThreeStooges'' shorts, where a sip or a swig of most alcohol may, for example, cause a Stooge to have steam fire out of his ears, or in an old Curly film (the one where he tries also eat oyster soup with disastrous results) when a single swig causes him to spin around on his bar stool.
* Dick (Jim Carrey) in the 2000s remake of ''Film/FunWithDickAndJane''. "He only had half a beer!"
* Tracy Lord (Creator/KatharineHepburn) in ''Film/ThePhiladelphiaStory''.
* Straight whiskey gets Theodora really wild in ''Film/TheodoraGoesWild''.
* Michael from the Danish film ''[[Film/TheCelebration Festen]]'' ''(The Celebration)''.
* ''Franchise/MarvelCinematicUniverse'':
** DoubleSubverted in {{Film/Thor}}. Erik Selvig can definitely hold his liquor, but when a mortal gets into a drinking contest with the Viking God of {{Boisterous Bruiser}}s... yeah, he loses.
** Again in ''Film/AvengersAgeOfUltron'': While having a party at Avengers Tower, Thor and Captain America are drinking with several World War II veterans. Thor and Cap are taking shots of Asgardian mead he says is "not meant for mortal men." [[Creator/StanLee One of the vets]] boldly retorts that neither was Omaha Beach[[note]]One of the American landing zones during the invasion of Normandy, and a bloody hell on earth[[/note]] and insists on joining in. One cut (and one shot) later we see him being carted off blitzed out of his mind, with another of his buddies catatonic in the background.
--->'''Veteran''': Ex-''cel''-sior!
* ''Film/TheHidden'': Detective Tom Beck offers his temporary FBI partner Lloyd Gallagher a beer after he invites him for dinner with his wife. Gallagher, who unknown to his partner is actually an alien cop [[PuppeteerParasite residing in a human host]], apparently can't stand the taste and has a hangover from just a few sips.
* ''Film/StrokerAce'': Pembrook is a Sunday school teacher and has sworn off most vices, including drinking. It seems like this is going to be subverted since it takes Stroker some time and coaxing to get her drunk, and then it's played straight when, after she's sufficiently drunk to agree to sleep with Stroker, she passes out in the bed about a second before Stroker can follow her back inside the hotel room.
* Roger Rabbit in ''Film/WhoFramedRogerRabbit'' literally [[HighPressureEmotion becomes a steam whistle]] after a single shot of bourbon. The reaction is demonstrated early on in the movie, and then exploited by Eddie to create a distraction so that he and Roger can escape from the villains.

* In the ''Literature/SweetValleyHigh'' book ''A Night to Remember'', Elizabeth and Sam get wasted by ''sharing'' one cup of spiked punch.
* In ''Literature/TheHungerGames'', Katniss gets dizzy from just drinking half a glass of wine. Later, she mentions that even the smell makes her sick. Then in ''Catching Fire'' she gets messed up after a few gulps of white liquor, did ''not'' hold most of it, and had a serious hangover the next day.
* Played with in ''Literature/TheThreeMusketeers''. D'Artagnan and Athos sit for a drinking bout after about half the book. Athos tells D'Artagnan his family history, and D'Artagnan pretends to pass out to not have to listen to any more. Athos comments that "Young people today can't hold their liquor. Even that one, who is one of the best." His judgment might be just a bit skewed due to drinking around 150 bottles over two weeks.
* One of Creator/IsaacAsimov's ''Azazel'' stories is about a woman who was too self restrained, and who could never relax because even one drink made her really sick. Well, the main character called for the titular demon and they remade her metabolism. The problem is, [[spoiler:she acquired such a taste, that the new metabolism made her really fat due to overconsumption]].
* Inverted in ''Literature/TheLegendOfSunKnight.'' EverybodyKnowsThat the Sun Knight is a man who will turn red after the first cup, get a headache after the second, and fall unconscious after the third. In order to act this out, all Sun Knights have been trained to [[NeverGetsDrunk never get drunk.]]
* In the ''Literature/{{Spaceforce}}'' series, the Taysans ''en masse'' react so badly to alcohol that even drinking slightly fermented fruit juice can turn them violently aggressive or sexually disinhibited. Apparently brewing and selling this illegal substance is one of the few instances of widespread criminal behaviour amongst the Taysan people.
* Subverted in ''Literature/StrangerInAStrangeLand''. Michael, having never had alcohol, is very susceptible to it; but having complete control of his body chemistry, he can also sober himself up at will.
* In ''Literature/AnimalFarm'', Squealer and Napoleon end up demonstrating exactly why animals should never drink alcohol, period, even when it isn't in excess, when they end up completely plastered from what is presumably their first drink of alcohol. A horrendous hangover ensues: the other animals are told that Napoleon is dying and has issued a decree that alcohol consumption was to be punished by death.
* Fitz, from the ''Series/DoctorWho Literature/EighthDoctorAdventures'', DependingOnTheWriter. He usually seems to have an above-average tolerance for alcohol: he once drank a whole bottle of wine and remained capable of walking, talking, and assisting in the Doctor's IndyPloy. However, in ''Camera Obscura'', Sabbath gives Fitz and Anji brandy, and Fitz falls asleep/passes out after one glass. Maybe he was just tired, [[TheWoobie poor dear]]. (Anji sips it slowly and suffers no appreciable effects.) But in the one ''AudioPlay/BigFinishDoctorWho'' story Fitz is in, he seems to have more of a tolerance than Anji, and mistakenly gives her a GargleBlaster that knocks her out for twenty-four hours (the Doctor scolds him, because he should have known that you're supposed to only put a single drop on a sugar cube), but goes around drinking it from a hip flask himself.
* ''Literature/TrappedOnDraconica'': There's a reason [[BigSisterMentor Daniar tells Erowin not to drink.]] Just one can make her drunk enough to jump on stage and dance. Justified as she's a young teenager.
* Turns out to be a plot point in ''[[TabletopGame/ForgottenRealms Curse of the Azure Bonds]]''. [[ActionGirl Alias]] is drunk after just two beers [[spoiler:because she is an artificial being that's only a few months old]].
* House-elves in ''Franchise/HarryPotter'' can get blind stinking drunk from butterbeer, a mild malt beverage whose alcohol content is so low that its sale to (human) minors is not restricted. {{Justified|Trope}} due to the fact that a house-elf is roughly half the size of an adolescent human, along with a possible dose of BizarreAlienBiology.
* In ''[[Literature/EddieLaCrosse The Sword-Edged Blonde]]'', Andrew Reese was the violent, non-comedic version of this — a "good man" when sober, but a violent would-be rapist as soon as he got hold of liquor. It's the root cause of all his troubles, and therefore, of the whole book.
* In ''Literature/TheIronTeeth'' Blacknail the goblin gets roaring drunk after a single mug of beer. He then passes out and wakes up with a hideous hangover. This can be somewhat explained by his small body mass.
* In the ''Literature/KharkanasTrilogy'', Galar Baras can't stomach alcohol, although he never explains what exactly it does to him.
* ''Literature/VillainsByNecessity'': Sam almost never drinks since it could potentially interfere with his job, and he needs to keep his instincts and reflexes honed. As a result, when he does drink he goes down fast, though Arcie just attributes this to Six Landers' innate "fragility".
* In ''Literature/TheGirlFromTheMiraclesDistrict'', despite having a HealingFactor, Robin manages to get himself smashing drunk on an hour-long flight - and not even throughout the entire flight, he's already singing shortly after they reach the cruise altitude.

[[folder:Live-Action TV]]
* ''Series/OneThousandWaysToDie'': A very ''dark'' example. One of the victims was an Amish kid on his Rumspringa, who was invited to a Halloween party by a bunch of hot girls, and ended up getting drunk. Problem was, he had a rare condition which prevented him from [[OhCrap digesting alcohol]], and was poisoned. He was one of those rare deaths from something that [[TearJerker really wasn't his fault]].
* ''Series/BabylonFive'':
** Vir is different from most other Centauri in the fact that he doesn't handle liquor well. In one episode he takes a sip of Londo's drink and promptly collapses. He later builds up his tolerance, [[DrowningMySorrows drowning his sorrows]] after he [[spoiler:killed [[TheCaligula Emperor Cartagia]] in "The Long Night."]]
** The ''entire Minbari race''. Give them only a little, and they turn into violent psychotics. Naturally, teetotalling is part of their culture. Explained via BizarreAlienBiology -- despite being relatively HumanAliens, their bodies don't process alcohol the way ours do.
** Late in the series, Londo discovers that drinking enough will knock out [[spoiler:the Drakh Keeper attached to him]], giving him brief periods of drunk-but-functional freedom thanks to his history of drinking giving him a high alcohol tolerance while [[spoiler:the Keeper]] is unconscious.
* Max gets incredibly drunk from a small sip of whiskey in an episode of ''Series/{{Roswell}}''; it's explained that he has less tolerance due to being an alien.
* Done for laughs on ''Series/UglyBetty'' when Henry gets full-out drunk on half a wine cooler.
* Lucy Ricardo on ''Series/ILoveLucy'' actually got completely plastered twice from two products that were only sort of alcoholic: Vitameatavegamin, some sort of vitamin/nutritional supplement that technically had alcohol in the same way that Ny-Quil does [[note]](though Ny-Quil is 25% alcohol by volume, so you ''could'' get drunk on the stuff)[[/note]], and once from water that had apparently been spiked. In the first case one reason this happened is because they had to keep reshooting the scene.
* Carlton from ''Series/TheFreshPrinceOfBelAir'' is known to get drunk off of a single scoop of rum raisin ice cream.
* Subverted in an episode of ''Series/HogansHeroes''. Schultz and Newkirk go into a bar (the bartender is an underground agent Newkirk must make contact with). Newkirk orders a beer for Schultz and a bottle of schnapps for himself. Schultz gets totally drunk because Newkirk kept dumping shots of schnapps into the beer.
* In ''Series/TheHoneymooners'', Alice claimed that Ralph once got a three-day hangover from a slice of rum cake. (That's actually impossible, because prepared rum cake has no alcohol in it. What's in the small amount of rum that is used to make it evaporates when it is baked.) Regardless, when Ralph wanted to drink a bottle of wine simply to prove that he could, Alice poured it down the drain when he wasn't looking and replaced it with grape juice; Ralph and Norton ''still'' got drunk from drinking it. (The fact that it happened to Norton was no surprise either, seeing as Trixie claimed that he "got tipsy just by reading the labels".)
* The trope shows up twice in ''Series/StarTrekVoyager'':
** Seven of Nine gets drunk on synthehol after drinking just one glass. As explained in an episode of ''Series/StarTrekTheNextGeneration'', the point of synthehol is it's a synthetic alcohol substitute meant to mimic the flavor of alcohol without getting you drunk, and it gives you the pleasant side of being intoxicated (buzz, relaxation, "light" feeling) without the negative sides (hangovers, lowered inhibitions, toxicity).
** In another episode, an alien ambassador gets utterly hammered aboard the ship because his species' liver cannot process alcohol/synthehol. The plot revolved around keeping him from embarrassing himself too badly while an antidote is developed.
* The title character of ''Series/{{Monk}}'' got drunk from a few sips of wine.
* Played with in an episode of ''Series/{{Angel}}'' where Fred and Wesley are (unbeknownst to them) affected by a magical spell that makes them drunk.
-->'''Fred:''' I am totally drunkfaced!\\
'''Wesley:''' You just can't hold your... what are you drinking?\\
'''Fred:''' Nothing.\\
'''Wesley:''' You can't hold that!\\
'''Fred:''' Oh yeah? Lightweight! How much have you had?\\
'''Wesley:''' Including this... about a third of a half of this beer.
* Both Corky and Miles in ''Series/MurphyBrown'' can't seem to take more than one drink before they're out.
* Josh on ''Series/TheWestWing'', who can barely handle two drinks with his "very sensitive system," according to his assistant Donna. She finds him passed out in his office one morning after a bachelor party, and there was apparently also an incident where he showed up at her apartment and yelled at her roommate's cats.
* Done once on ''Series/{{Scrubs}}''. J.D., Turk, and Elliot are out drinking. Elliot proclaims "I have magic breasts," and passes out at the bar.
-->'''J.D.:''' How many has she had?\\
'''Turk:''' (''picks up Elliot's beer bottle'') Almost one.
* Richie from ''Series/{{Bottom}}'' only needs a single sip of liquor to get drunk... or at least to ''think'' that he's drunk, which amounts to the same thing. It's more likely that it's all in his head -- on one occasion, he takes a quick shot to settle his nerves, and only after it does the trick does he find out that it's a soft drink.
** Rick, played by the same actor on ''Series/TheYoungOnes'', once passed out at a party after half a glass of cider, and staggered home so wasted that he apparently put himself to bed without realizing an escaped murderer had broken into the house and was asleep in his bed. He wakes up with no memory of the party's events, realizes the killer (who is female) is there, and leaps to all the wrong conclusions.
* Sam Ballard of ''Series/RumpoleOfTheBailey'' is fall-on-the-floor drunk after a mere five small glasses of sherry--perhaps enough to make most people a bit tipsy, but not much else. In the event, Ballard is so drunk he only thought he had three or four. Claude Erskine-Brown kindly informs him of the truth. In a later episode, he is seen laughing hysterically and falling down next to a wall. While we don't hear how much he had to drink, it is very clearly implied that it wasn't all that much.
* An entire episode of ''Series/{{Blackadder}} II'' centers around the title character's inability to tolerate strong drink. It takes him all of forty-two seconds to get roaring drunk after downing a flagon of ale.
* Tom Haverford, the resident CasanovaWannabe of ''Series/ParksAndRecreation''. As [[UsefulNotes/{{Basketball}} Detlef]] [[AsHimself Schrempf]] put it (watching Tom making a complete ass of himself at a bar):
-->'''Detlef Schrempf:''' He had two beers. Light beers.
* In ''Series/TheBigBangTheory'', Sheldon has gotten drunk twice in the entire series and both times he severely embarrassed himself. Also applies to coffee and valium.
-->'''Sheldon:''' (''waking up after his award speech where he drank some wine'') Where are my pants?\\
'''Leonard:''' [[InstantHumiliationJustAddYouTube You might want to check]] Website/YouTube.
* ''Series/MyNameIsEarl'': Randy is perfectly competent after four beers -- but after number five...
* Bunk Moreland on ''Series/TheWire''. His best friend, the Irish American Jimmy [=McNulty=], is definitely less of a lightweight.
* In ''Series/{{MASH}}'', Frank Burns can't hold his liquor and readily admits it. Also, beer goes through him rather fast (a trait that Hawkeye and Trapper cleverly took advantage of in one episode to get a urine sample from him.)
** Radar as well. Justified seeing he's often too timid to drink, so he wouldn't have much of a tolerance. In one episode, he attempted to [[DrowningMySorrows drown his sorrows]] upon facing a court martial for a crime he never committed, and ended up getting sloshed. Klinger asked him how many drinks he had. He was barely on his second one.
* In one episode of ''Series/UnhappilyEverAfter'', Tiffany eats one rum ball, gets black-out drunk and has to spend the rest of the episode figuring out [[WhatDidIDoLastNight what she did under the influence]].
* ''Series/DoctorInTheHouse'' and its sequel series feature two examples.
** Lawrence Bingham, who appears in ''Doctor at Large'' and ''Doctor in Charge'', is teetotal, generally sticking to tomato juice when at the hospital bar. In several episodes, the other doctors spike his drinks or secretly order him a Bloody Mary instead, and it only takes one or two to get him fall-down drunk.
** James Gascoigne in ''Doctor on the Go'' only ever drinks the odd half pint; any more than that and he is too drunk to function. So when he drinks half a pint of ''whiskey'' in "For Your Own Good" after a fight with his father, he signs the elder Gascoigne up for every painful medical test he can think of in a drunken haze.
* The "stag party" montage in ''Series/{{Sherlock}}'' has Sherlock and John bar hopping, with Sherlock insisting on using large graduated cylinders for a precise volume of beer. The sequence makes it look like Sherlock knows exactly how much liquor both of them can take. What he didn't realise is that John was adding shots to the beer, ruining his calculations. Then they get absolutely wasted and go to Sherlock's place to sleep it off. Mrs. Hudson comes up and reveals that they've only been out for 2 hours. It's pretty lame.
* On ''Series/{{NCIS}}'', Team Gibbs uses Jimmy Palmer's StagParty as part of a sting. All the drinks are watered down, but Palmer still gets hammered.
* On ''Series/{{Chuck}}'', Emmett (Chuck's season 2 SitComArchnemesis) is boring enough that he gets absurdly hung-over after a drunken poker game relative to the amount he actually drinks.
-->'''Emmett''': I should never have gone for that second Fuzzy Navel. That wine cooler had ''4%'' alcohol.

[[folder:Professional Wrestling]]
* B-boy apparently got drunk on half a corona glass in between Wrestling/ProWrestlingGuerilla shows.
* Wrestling/LondonAndKendrick's "broke into" the [[Wrestling/RonSimmons Acolyte]] [[Wrestling/JohnBradshawLayfield Protection]] Agency's office on WWE Velocity to celebrate a victory, leaving the APA upset that someone was drinking their beer. Their anger soon became amusement though when it became clear the two had no tolerance for alcohol whatsoever. So much so the two were invited to their bar room brawl at a Smackdown pay per view. Incidentally, Paul London is [[TheTeetotaler a teetotaler]] in reality.
* When Wrestling/KevinNash was running Wrestling/{{TNA}} Impact, he only allowed [[Wrestling/LisaMarieVaron Tara]] and ODB, who were feuding at the time over Tara being a "[[RealWomenDontWearDresses diva]]", their hardcore grudge match to take place if they each drank a six pack of beer first. ODB seemed unaffected but Tara, who didn't even know what liquor was, was at an insurmountable disadvantage.
* During JakeRoberts' "born-again Christian" gimmick and subsequent feud with JerryLawler over Roberts' battle with alcoholism, Roberts once staggered to the ring, bottle in hand and appeared to be highly intoxicated. GorillaMonsoon -- not knowing what was going on (or perhaps he did) -- came out to get Roberts and usher him back to the dressing room, but Roberts eventually managed to climb into the ring, where Lawler was insulting Roberts and calling him a drunk. This was, of course, averted, as the perfectly-sober Roberts eventually grabbed Lawler and DDT'ed him, before pouring liquor on the loud-mouthed King's face.

[[folder:Puppet Shows]]
* In ''Series/LesGuignolsdelinfo'', the puppet from François Bayrou. He can get drunk on non-alcoholic beer (or other harmless, alcoholic-looking beverages found in France). Once, trying just one draught of ''panaché'' (shanty) put him in an alcoholic coma. Naturally, sketches often paired him with [[TheAlcoholic hard-drinker]] Jean-Louis Borloo.

* ''Radio/TheNavyLark's'' Sub-Lieutenant Phillips, drunk beyond belief on half a Lemonade Shandy.

[[folder:Tabletop Games]]
* ''TabletopGame/{{GURPS}}'' has the Alcohol Intolerance Quirk to represent this.[[/folder]]

* In Creator/WilliamShakespeare's ''Theatre/{{Othello}}'', Cassio can't hold his liquor, but Iago pressures him into toasting Othello. Turns out Cassio is a violent drunk and the resulting fights with Roderigo and Montano lead to Othello firing Cassio. Readers will know that this is actually part of Iago's EvilPlan.

[[folder:Video Games]]
* [[TeamDad Kim Kaphwan]] from ''VideoGame/FatalFury'' and ''VideoGame/TheKingOfFighters'', [[AllThereInTheManual according to side notes]] and as seen in [[http://www.youtube.com/watch?v=syewNvULmL0 the Fatal Fury Team]] ending of ''The King of Fighters XI'' -- where he apparently got plastered on ''one mug of beer''.
** In [[http://www.vgmuseum.com/end/neogeo/a/kof95england.htm the Women's Team ending]] of ''KOF 95'', both Mai Shiranui and Yuri Sakazaki are drunk off their butts much to the annoyance of King. Neither girl has "gotten better" in these regards by the time ''XIII'' rolls, as [[http://youtu.be/hSRZQk-TJBw?t=4m53s King tells Athena]] when she says she wants to join the Women's Team [[https://www.youtube.com/watch?v=35iWEB7QIvs and the ending shows.]]
* ''VisualNovel/{{Tsukihime}}'' has [[{{Meido}} Hisui]]. During the small welcoming party her, Kohaku, and Akiha throw for Shiki after his arrival at the mansion, drinks are served and she's the first casualty, despite drinking the weakest drink. In her route, one thing leads to another and Shiki wakes up the next morning in bed with her...though after the initial shock they determine nothing inappropriate took place while they were drunk.
** Shiki himself may count due to [[IllBoy his poor health]], though he knows to moderate himself.
* Blaise in ''VideoGame/RuneFactory3'' doesn't drink because of a NoodleIncident that he cannot remember and no one will elaborate on, besides looking embarrassed and urging you to '''never''' give him alcohol.
* Ronaldo in ''VideoGame/DevilSurvivor2'' might as well be the king of this trope. He is reduced to stumbling and slurring his speech after being force-fed ''a single liquor chocolate''.
* ''VideoGame/ResonanceOfFate'': In an early cutscene, Zephyr takes a single sip of champagne... only to spit it out and break into a coughing fit.
* ''Franchise/MassEffect'':
** In ''VideoGame/MassEffect2'' Jack accuses Shepard of this when s\he passes out after one drink on Omega. This is a subversion, though: Shepard's cybernetic enhancements make him/her far more ''resistant'' to alcohol; what knocked him/her out was actual poison from the [[FantasticRacism human-hating]] batarian bartender. Jack herself might have been with Shepard in the toilets on the Citadel after drinking three of the strongest legal drinks, then smuggled Batarian ale, then ''radioactive'' Krogan liquor.
** Tali (unsurprisingly) and Javik (much more surprisingly) are shown to be this in ''VideoGame/MassEffect3'' and its ''Citadel'' DLC. (The latter, even if your party is relatively sedate, includes Tali sitting on the bathroom floor rambling in hilarious non sequiturs.)
* An [[NewGamePlus Avatar of Boris]] in ''VideoGame/KingdomOfLoathing'' cannot drink past five Drunkenness, while the starting limit for regular character is fifteen. Boris's alcohol tolerance was very low.
** When you [[spoiler:fight him at the end of the Avatar of Jarlsberg path]], it's revealed the reason for Boris's low alcohol capacity is not because he can't hold his liquor, but because he has to limit his intake so that he can keep his physical form at its peak.
** The Zombie Slayer path, in which you're a zombie, has the same limit. Alcohol does weird things to a zombie.
** The Avatar of Jarlsberg, meanwhile, has a limit of ten in both Drunkeness ''and'' Fullness, due to his [[PickyEater intensely fastidious eating habits]]; however, he can learn skills that raise both to the normal line.
** In the Actually Ed the Undying path, Ed starts off unable to eat or drink at all, what with being a mummy without any organs and all. He can buy replacements, though. The Replacement Liver comes from a church-going little old lady, and only has a Drunkenness limit of five.
* ''VideoGame/SuperRobotWars'' has two examples:
** Sanger Zonvolt, a well-built German samurai, and quite possibly the most badass character in a game full of badasses, will faint at the slightest taste of alcohol.
** Then there's Tetsuya Onodera, Executive Officer of the Hagane, and later Captain of the Kurogane. After drinking a glass of sake with Captain Daitetsu Minase, he gets sick during an enemy attack and must give command to ''BridgeBunny'' Eita until the captain returns.
* The title character of ''VideoGame/{{McPixel}}'' falls into this, as demonstrated in a level where he gets drunk off a drink that is revealed, on close up, to be 1% Alcohol. He gets so blitzed he groin kicks Guy Fawkes and ends up destroying the bombs he has to defuse that level in the process.
* ''VideoGame/BioShockInfinite'': Strangely enough considering that Booker more or less crawled inside a bottle and never left after [[spoiler: giving up his daughter, Anna, to Comstock]], picking up ''one flask'' of whiskey gets you blind stinkin' hammered, [[InterfaceScrew giving Booker double vision and making him wobble as he walks]], and making it much harder to fight if you accidentally grab a bottle during the middle of a shootout.
* Cookie Masterson in the Language floor of ''VideoGame/YouDontKnowJack The Ride".
* ''VideoGame/BarOasis'': Even though Kane looks to be the toughest biker in all of England, he becomes a babbling, crying mess as soon as alcohol touches his lips. The Boss tells you that if he should order a Singapore Sling, you should serve him a Shirley Temple instead. Alternatively, switch a Cinderella for a Margarita.
* ''Franchise/SuperMarioBros'':
** They don’t have this in the American version, but in ''[[VideoGame/WarioLand Wario Land 2]]'', there’s a penguin-like enemy that throws beer in Wario’s face, which causes him to get plastered rather quickly. (Meaning Wario fits this Trope to a T, seeing as he’s a big guy, and beer is, at most, 5% alcohol.) Incidentally, the American version has the bird throw a bomb at him; clearly, the censors think bombs are okay, but drunkenness is not.
** Believe it or not, Princess Peach fits too, and wine is something you should keep away from her. (No, this is ''not'' from a fan art version.) In ''VideoGame/SuperMarioKart'', they give the winner a bottle of champagne; they don’t drink it in the American version, but they do in the original Japanese. Bowser even gulps the entire bottle, but seeing as he’s a huge turtle-monster, he doesn’t even get tipsy. Peach, on the other hand, if she’s the winner, does the same thing, and gets seriously soused. (Champagne is about 12% alcohol content, by the way; this scene comes as a shock to any American player.)
* You have to wonder why Tiki in ''VideoGame/DragonsCrown'' even tries to drink, seeing as she’s a tiny little fairy; even one goblet of wine would likely make her pass out. And it does. Every time you go to see her in the tavern, she’s passed out in the half-empty goblet of the wine she tried to drink, drunk.
* ZigZagged in the drinking contest minigame in ''VideoGame/TheWitcher''. The trick is that the game tracks Geralt's drunkenness by the alcohol content of what he's drinking, but only tracks the ''number of drinks'' for his opponent. Drink only beer and you're golden, but if you drink wine or hard liquor you'll typically have the magically mutated monster hunter getting drunk under the table by some random fat guy in a bar.

[[folder:Visual Novels]]
* ''VisualNovel/{{Clannad}}'': Nagisa Furukawa turns love-love-jealous-drunk in the ''instant'' she drinks a cup of sake. HilarityEnsues.
* Both Mary Clarissa and Angie in ''VisualNovel/ShikkokuNoSharnoth'' have next to no alcohol tolerance. When Angie is described as getting drunk quicker than even Mary, who is tipsy after a single drink, you know it must be bad.
* Chris in ''VisualNovel/MajiDeWatashiNiKoiShinasai'' pretty much gets instantly inebriated whenever the [[FrothyMugsOfWater Kawakami Water]] comes out. Played for hilarious effect in her own route, where it leads to [[spoiler: a threesome with Margit]].
* Stunt in ''VisualNovel/{{SC2VN}}'' quickly passes out after a night of drinking. It helps that he's still a high school kid.
* [[spoiler:Hanyuu]] from ''VisualNovel/HigurashiWhenTheyCry'' can [[{{Synchronization}} taste]] what [[spoiler:Rika]] drinks. She [[DoesNotLikeSpam hates alcohol]] so [[spoiler:Rika]] often drinks wine (or eats spicy foods) in order to punish her. [[spoiler:[[TroublingUnchildlikeBehavior Rika]] is [[VagueAge nine to ten years old]] while [[CuteGhostGirl Hanyuu]] died as an adult, which adds a bit of irony to the fact Rika handles liquor better than Hanyuu.]]
* Uendo Toneido in ''VisualNovel/PhoenixWrightAceAttorneySpiritOfJustice'' is such a lightweight that he gets knocked out from eating half of a sake-filled manju bun. [[spoiler:It's enough to knock out all three of his {{split personalit|y}}ies at once!]] This may have something to do with [[spoiler:his hidden fourth personality which only comes out when the other three are indisposed.]]

[[folder:Web Comics]]
* Walky from ''Webcomic/ItsWalky'' gets ''really'' drunk after ''a sip of beer''. His sister Sal is shown to have the same problem in a following strip. As stated by Joyce, it's a family trait. This is shown to be true of their various [[Webcomic/DumbingOfAge Dumbiverse]] counterparts as well.
* Jimmy from the Filipino newspaper and web comic ''[[http://www.beerkada.net/ Beerkada]]'' is so bad at holding anything even remotely resembling liquor that he gets tipsy from ''shandy.''
* Subverted in ''Webcomic/QuestionableContent''. Strips [[http://www.questionablecontent.net/view.php?comic=718 #718]] - [[http://www.questionablecontent.net/view.php?comic=719 719]] has Faye (and later the rest of the cast) getting hammered from a few sips of bourbon. It is discovered almost immediately that the drink was no ordinary bourbon. Not to mention the bottle was ''glowing''. It came in it's own metal case.
** Justified for Tai, who is simply so small that it doesn't take much.
** Steve gets homo tendencies when drunk, usually for an unamused Marten. In one such case, Jeph's rant at the bottom of the page mentions that Steve only had two drinks.
* Florence from ''Webcomic/{{Freefall}}'' has a very low alcohol tolerance as confirmed by WordOfGod, which makes [[http://freefall.purrsia.com/ff1600/fc01525.htm this punchline even funnier]]
* In ''Webcomic/{{Mindmistress}}'', the title character once got drunk with only one cup of alcohol.
* In season 2 of ''Webcomic/{{Sidekicks}}'' Lamia gets drunk enough to pass out after taking a single swig from her hip flask.
* The [[PettingZooPeople Keidrans]] in ''Webcomic/TwoKinds'' have this problem. They get completely smashed off a mouthful or two of normal Ale (Which is actually a very weak liquor). Side effects may include talking like WebOriginal/LOLCats.
* In ''Webcomic/{{Seekers}}'' Giselda passes out after one cup of straight liquor.
* ''Webcomic/BittersweetCandyBowl'', Mike becomes drunk easily when accepting a bet to eat liquor candy in the confrontation arc.
* In ''Webcomic/{{Exiern}}'' after her [[GenderBender transformation to a woman]] Tiff discovers it now [[http://www.exiern.com/?p=48 only takes two drinks]] to get her really drunk. She doesn't see this as a bad thing though since [[HardDrinkingPartyGirl she likes being drunk]] and this means she can do it more quickly.
* In ''Webcomic/TreadingGround'', Aya manages to get drunk on a single O'Douls (a "beer" with only 6 proof).
* In ''Webcomic/DubiousCompany'', after [[TheDragon Izor]] is ignored by his elite guard, he [[GoKartingWithBowser goes drinking]] with Tiren and Walter. When the guards return to pick him up, he's so plastered he [[DoomedNewClothes vomits]] on Mary. Given how much [[HardDrinkingPartyGirl Tiren]] and [[DrunkenMaster Walter]] drink, it's hard to tell whether Izor is this, or he was [[DrinkingContest drunk into oblivion]].
* ''Webcomic/{{Sunstone}}'' has Allyson who has a complete inability to keep her secrets down once she's touched alcohol, she also looses her ability to restrain the dom tendencies in her BDSM relationship with Lisa.
* ''Webcomic/PvP'''s Francis Ottoman had an interesting reaction to his [[http://www.pvponline.com/comic/2006/12/31/dec-31-2006 first beer.]]

[[folder:Web Original]]
* The Franchise/{{Spider-Man}} running joke mentioned under Comics above is referenced in ''WebVideo/ImAMarvelAndImADC'', in which Spider-Man usually orders milk at the bar, and when he ''does'' drink he spends the next few episodes in a drunken stupor babbling parodies of other blockbuster movies, although it's mainly because the other heroes constantly spike his drinks in order to enjoy said parodies.
* Most of the cast of ''FanFic/TheMadScientistWars'' is capable of slugging back drinks probably capable of killing a normal man -- with one noticeable exception. Commander [[DaChief Primary Xerox]] is, surprisingly, capable of getting hammered on a half a cup of banana daiquiri. This is explained in-game however, as he has been stated to have a mild healing factor powered by an insanely high metabolism -- so the alcohol is absorbed into his system faster then it should be. At least he won't get alcohol poisoning...
* ''WebVideo/TheNostalgiaCritic'':
** In his ''Literature/{{It}}'' review, it's only ten minutes before his speech is slurred and he's grinning sloshedly.
-->'''Critic''': The camera's purdy.
** Perhaps Doug Walker himself. On the commentary for ''It'', he says one of the very few drinking games he's tried to play in real life is the ''Series/RedDwarf'' drinking game (Take a shot every time Kryten explains some technobabble). He didn't make it through a single episode before puking and passing out. [=EgoRaptor=] and Rob have also said that if he had actually been drinking as the Critic, the clothes would have come off fast.
* Seemingly nobody in WebAnimation/PeteraDzive can handle drinking booze without passing out instantly. The series exploits this for humorous effect.
* There have been Creator/RoosterTeeth Podcasts talking about the exploits of the others and these kinds of incidents. Incidents including Lindsay Jones locking out Creator/MichaelJones and Creator/GavinFree while she slept in their hotel room, Gavin drunkenly hitting on Creator/MontyOum, Gus Sorola losing to Michael in an arm wrestling and declaring "I HAVE NO DICK!" and Matt Hullum paying for everyone's dinner and ending up broke for it.

[[folder:Web Video]]
* Orma, the female Orc Barbarian of the party in WebVideo/HeroesAndHalfwits is such a lightweight that she gets knocked out with even the smallest of drinks. A problem exacerbated by the fact that she ''never'' turns down a drink and tends to be a [[IdentityAmnesia very different person when she wakes up.]]

[[folder:Western Animation]]
* In ''WesternAnimation/InspectorGadget'', the title character once got drunk from a small cup of soda. On the other hand, later in the series, he's shown drinking from a pint of beer with no problems--that spiked soda could have been something much stronger.
* Peter Griffin from ''WesternAnimation/FamilyGuy'' has gotten drunk from drinking a sip of Communion wine (which is very watered down in some places, although other parishes use nearly-neat fortified wine with only a symbolic drop of water) and has passed out from taking one lick of butter rum ice cream, just to name a few examples. The weird thing about Peter is that once he does get drunk, he sort of plateaus and doesn't appear to get any drunker no matter how much he has.
* Stan Smith in ''WesternAnimation/AmericanDad'' turns out to be such in one episode where he starts insisting Francine make him a martini every day after work. Granted a martini is a fairly strong cocktail as she warns him.
* Jay Sherman (and Marty) from ''WesternAnimation/TheCritic''. When they went to France, a waiter offered them a small glass of wine. Cut to a few minutes later, with the glass still almost full, but both plastered.
* ''WesternAnimation/AdventuresOfSonicTheHedgehog'': Scratch and Grounder collapse after sharing a bottle of alcohol in a Sonic Sez.
* ''WesternAnimation/{{Metalocalypse}}'': Pickles, despite his reputation for being TheStoner in the band, and even being [[ImmuneToDrugs completely immune to the negative side effects to one of the most deadly (fictional) drugs ever created]], can't drink much without getting completely wasted. In fact, he had to be sent to rehab -- not for his massive drug abuse, but because he can't drum with a measly few beers in him.
* Parodied in an episode of ''WesternAnimation/TinyToonAdventures'', where Buster, Plucky, and Hamton ''split'' a single beer, and proceed to go on a drunken bender that ends with a car going off a cliff. It was pretty much a spoof of {{Anvilicious}} DrugsAreBad stories.
* Spoofed in ''WesternAnimation/TheAnnoyingOrange'', "Grapes of Wrath", when the gang visits a vineyard. [[CreatorCameo Dane]] is seen [[GettingCrapPastTheRadar getting "drunk" on grape preserves]].

[[folder:Real Life]]
* One common side effect of giving blood is to have one's tolerance significantly lowered, therefore it is not uncommon for regular drinkers to get drunk off only a few drinks after. This is why blood donors are instructed to wait several hours or eat a full meal after giving blood before drinking alcohol.
* Somewhat TruthInTelevision: about half of the population of people of Asian descent suffers from "Asian Flush," an inability to properly break down alcohol. Although they don't actually get drunk faster, a mere one or two drinks can lead to "nausea, headaches, light-headedness, an increased pulse, occasional extreme drowsiness, and occasional skin swelling and itchiness," which can be confused with being drunk. It's theorized that East Asians are less likely to express the genes responsible for making the enzymes that break down alcohol because traditionally East Asian civilizations boil water to make it drinkable, whereas Western ones add alcohol. Also true of Native Americans.
** Mark "LetsPlay/{{Markiplier}}" Fishbach is one such person, and noted that when he needed to drink for a video, he had to take medication to lessen the effects and stick to a responsible amount of alcohol. Even then, at one point he had a serious enough medical scare that he eventually had to swear it off altogether, ending the 'Drunk Minecraft' series.
* Under the right circumstances even experienced drinkers can pass out after a couple of mouthfuls of wine. A good way to get into serious trouble is to not eat or drink anything during a whole day, get a lot of exercise then drink some alcohol. Dehydration will make your blood alcohol content shoot through the roof and you'll be wasted after twenty minutes. At this point, if you don't drink any water, you'll start feeling very bad indeed (initial dehydration + usual effects of the drinks + alcohol-induced dehydration = high probability of passing out).
** Your blood alcohol content can also increase for a given amount of drinking if you have less blood--e.g. after significant bleeding or, more commonly, after donating blood. Hence the practice of some young daredevils of giving blood and promptly finding something to drink (for the higher intoxication), despite the fact that this is the ''exact opposite'' of what all of modern medicine says you should do.
* This can also happen to normal people who make the mistake of drinking before or during an airplane ride. The lesser air pressure exacerbates the effects of alcohol. On lesser scale, the same thing happens to people who come to Denver and drink at ski resorts. Many people also ''intentionally'' get themselves plastered before/during the flight, because they either are afraid of flying, or simply get quickly bored of sticking in the uncomfortable seat watching the same dumb movies for hours. In fact, if you're in business class, the drinks before or during are often free... and why let free drinks go to waste?
** The airlines know this and generally prefer their passengers [[InvokedTrope drunk and asleep over long flights]].
* UsefulNotes/UlyssesSGrant, despite his reputation as constantly drinking, was more likely this trope, which earned him the nickname of "One Beer Grant." He did however smoke like a chimney.
* Bees, as we learn from the Series/MythBusters, get drunk from being ''sprayed'' with vodka. This is because insects don't have lungs. Insects have pores throughout their body called spiracles so they can directly supply oxygen to their body. While quite efficient, it has an unfortunate side effect of rapidly allowing chemicals into their body when coated. This is why bug spray is so effective.
--> '''Tory:''' Oh, it's terrible! They're drunk!
** In certain parts of Texas scorpions are very common, and if people catch them, they like to put two together in a box, and pour a bit of beer on them. The result? '''[[CrazyAwesome DRUNKEN SCORPION DEATHMATCH]].'''
* People that have had gastric bypass surgery absorb alcohol into their systems faster than they used to.
** Similarly, people who have lost significant amounts of weight in a short time period will often find that their alcohol tolerance has gone down, because there's simply less of them there to absorb the alcohol.
* Can be seen in people who are used to drinking one type of alcoholic beverage who try another one with a higher alcohol content but a similar taste: they'll drink at the pace they are used to which is too high for what they are actually drinking. Odd-40% alcohol beers [[http://beernews.org/2010/02/schorschbrau-schorschbock-40-trumps-brewdog-tactical-nuclear-penguin/ Schorschbock]] and [[http://www.brewdog.com/sink_the_bismark Sink The Bismark]] are ''not'' meant to be drunk in one gulp like people do with ordinary beers, which is a bit natural since they have the potency of malt whiskey.
* After having an extreme case of Glandular Fever (mononucleosis, "mono", or the kissing disease to [[UsefulNotes/ThePond Leftpondians]]) a person will find out that they have a lower tolerance to alcohol.
* [[Music/{{Megadeth}} Dave Mustaine]] was kicked out of Music/{{Metallica}} because unlike the other members of the band (who were [[SentimentalDrunk "fun" drunks]]), Dave was a mean, violent drunk who liked to start fights with people when he was intoxicated. It got him fired twice; once for violently attacking Hetfield and [=McGovney=] and threatening Ulrich in a dispute over his dog (granted, Hetfield did himself no favors by kicking said dog after it scratched up [=McGovney=]'s car; nonetheless, Mustaine was allowed back in the day after), and a second and final time due to his excessive drinking, drug problems, proclivity for violence, and exceedingly abrasive personality. His actions also led to [=McGovney=] leaving, as he drunkenly poured beer down the neck and into the pickups of [=McGovney=]'s bass, shocking him when he later tried to play it; this resulted in [=McGovney=] kicking Mustaine out of his house and opting to leave the band not long after.
* While no specific names were mentioned, [[Music/HourOfPenance Davide Billia]] and Paolo Chiti left Putridity at the same time after a long history of inter-band tensions caused by at least one member being a mean, violent drunk culminated in a weekend that was supposed to be devoted to hanging out and practicing but wound up going so poorly that Billia and Chiti quit on the spot and drove four hours home rather than subject themselves to one more second of abuse.
* It wasn't mentioned in the press release, but a heated Facebook exchange with Brent Purgason revealed that this was why Kim Dylla was fired from Music/{{GWAR}}. She apparently had a major problem with not knowing her limits and would regularly drink massive amounts of alcohol before going onstage, where she would invariably perform very poorly because she was completely fucked up (fans who saw them during her time as Vulvatron noticed that she was slurring her words, visibly staggering, and often could not lift her own props), and the final straw was when she broke a rib onstage while in a drunken stupor. As the argument spiraled on, her attempts to rationalize what she could and downplay what she couldn't dug her deeper and made it plainly obvious that she had a serious drinking problem and was in complete denial. A very messy recent incident where she drunkenly assaulted Danny Leal from Upon a Burning Body and completely fabricated most of her side of the story to make herself look better has ''not'' helped her case.
* [[Music/ToshimitsuDeyama Toshi]] of Music/XJapan is the "passing out" version of the trope: He's said in interviews that he likes beer but falls asleep after two. Possibly a case of CursedWithAwesome or BlessedWithSuck, because his bandmates had ''far'' worse alcohol problems.
* People on antidepressants and anxiolytics find out pretty quickly that they can no longer tolerate liquor. People on [=MAOIs=] should completely avoid liquor because of this. [=SSRIs=] merely make alcohol absorption more efficient.
** People taking lithium for bipolar disorder are commonly told to avoid alcohol. It's not that it makes getting drunk easier, it just makes the hangover ''worse'' -- dehydration (a normal side effect of too much booze) throws lithium levels out of whack.
* Certain mushrooms, such as the [[https://en.wikipedia.org/wiki/Coprinopsis_atramentaria inky cap]], can destroy one's alcohol tolerance (by causing almost instant hangover) for a few hours after consumption.
* Women as a general rule are much more susceptible to the effects of alcohol then men, due to body composition, size and different enzymes between male and female bodies.