[-[[caption-width-right:241: The experiment ForScience has [[GoneHorriblyWrong gone horribly wrong]], the EldritchAbomination has escaped its [[WhatCouldPossiblyGoWrong perfectly safe]] ContainmentField and is now [[SurvivalHorror picking us off one by one.]] Needless to say, it went FromBadToWorse.[[note]]Top to bottom: ''VideoGame/MOTHER3, VideoGame/BioShock1, VideoGame/MetroidFusion''.[[/note]]]]-]

The Abandoned Laboratory is a common setting in SpeculativeFiction. But when you place it into a video game, it becomes quite the tour of science gone horribly wrong.

Usually a task set out after finding rumors about a MadScientist. You decide to head to the Abandoned Laboratory, where you are greeted by hostile security units who do not want you to enter the deeper parts of the lab. They are often however no match for whatever lies below, whether it be discarded SuperSoldier projects, sentient [[AIIsACrapshoot robots who plan to exterminate all life]], or horrible masses of biological life which smell dinner. Often they are an evolutionary sort, [[FreakLabAccident starting out with rejected lifeforms and ending up as deadly beings which have exceeded the creator's ambitions]] and can more than easily kill the hero in a heartbeat. Card Keys are a common staple of these wretched labs. Often, [[ApocalypticLog logs]] will lie about, speaking of first pride and then terror of their author's scientific pursuits.

Along the way, as you travel across the lab, you will go from a relatively sanitary environment to one where it feels disgusting just stepping on the ground. Vats full of the specimens lie dormant or are deceased due to being failures (however, if they are less than human, expect them to break free to start munching on something), bits of TechnoWreckage lie about as you realize you are near the scientist or his ultimate creation, which will grant the following...

#A GirlInABox or a SealedGoodInACan, both of which obviously join you.
#The place becomes a CollapsingLair, forcing you to get the hell out of Dodge.
#You recover a biological MacGuffin.
#A massive organic blob awakens, planning to turn you to genetic material.
#MotiveRant (You better get comfortable).

See also MadScientist, ForScience. Also overlaps with AbandonedHospital in some cases, with the hospital residents being used as test subjects.


* This is common in the ''VideoGame/{{Metroid}}'' games, with the earliest example being Tourian in the [[VideoGame/{{Metroid1}} first game]]. Tourian would appear again in ''VideoGame/SuperMetroid'' and ''VideoGame/MetroidZeroMission'', the latter of which is a remake of the first game; both of these later games make clear that the reason Tourian is abandoned is because the Metroids escaped and killed off the Space Pirates.
** ''VideoGame/MetroidFusion'' takes place pretty much entirely on one of these; B.S.L, a large space station full of various creatures from across the galaxy.
** ''VideoGame/MetroidOtherM'' takes place in a station quite similar to the one from Fusion, used as laboratory for researching biological weapons. In fact, it appears to be the predecessor to the secret research carried on the B.S.L station.
** Both games have their own "sectors", which also [[HailfirePeaks combine this setting with other settings:]]
*** Sector 1 of ''Fusion'' is a recreation the Metroids' homeworld, [[UndergroundLevel and is a pretty straightforward cave area.]] Sector 2 is a [[JungleJapes tropical area.]] Sector 3 is [[ShiftingSandLand half desert]] and [[LethalLavaLand half lava.]] Sector 4 is [[UnderTheSea aquatic.]] Sector 5 is [[SlippySlideyIceWorld frozen over]], and Sector 6 is [[BlackoutBasement dark and nocturnal.]]
*** The station in ''Other M'' has three main areas: [[JungleJapes tropical]], [[LethalLavaLand firey]] and [[SlippySlideyIceWorld icy.]]
** Every game in the ''VideoGame/MetroidPrimeTrilogy'' features at least one, usually belonging to the Space Pirates at some point. ''VideoGame/MetroidPrime3Corruption'' also featured a few that belonged to the [[TheFederation Galactic Federation]] and the Elysians, while ''VideoGame/MetroidPrimeHunters'' features two such labs that once belonged to the Alimbics.
* Shandor Island in ''VideoGame/GhostbustersTheVideoGame'', which overlaps with a HauntedCastle. It's abandoned, all right; it's loaded with black slime and filled with all manner of ghosts and ghoulies; there's untold amounts of weird occult science going on; and an imprisoned Juvenile Giant Sloar serves as the icing on this very nasty cake.
* ''VideoGame/TombRaiderLegend'' has Lara visit an abandoned Soviet laboratory in Kazakhstan. Well, the frozen bodies of the scientists who worked there are still lying around, so it counts as a tomb, yes?

* ''WesternAnimation/PinkyAndTheBrain: The Master Plan'' appears to consist entirely of this, level-wise.
* ''VideoGame/{{Shinobi}} III'' featured the third stage: "Body Weapon", where Joe battles robots, guards, and unleashed bioweapons. It culminates in a fight against a giant in a room full of MeatMoss.

[[AC:AdventureGame / VisualNovel]]
* VideoGame/TheWhiteChamber has one or two, depending on how you count. With card keys, at least one MadScientist and a GirlInABox (the player character).
* ''VisualNovel/NineHoursNinePersonsNineDoors'' featured a laboratory room. Although one wonders if it was ever actually used as such (then again Clover claims that it was in one of the random conversations you can get in the room).

[[AC: BeatEmUp]]
* The ''VideoGame/{{Splatterhouse}}'' series often takes place in such a level. Mainly because the mansion is/was used by Dr. West as a lab, and now is filled with monsters and demons.

* The [[UrExample Ur]]-FirstPersonShooter ''VideoGame/TheColony'' is set in an abandoned scientific outpost.
* ''VideoGame/{{Killing Floor}}'' with the Biotic Labs and the Bedlam map bunker.
* ''[[VideoGame/HalfLife1 Half-Life]]'''s Black Mesa Research Facility.
* ''[[VideoGame/FirstEncounterAssaultRecon F.E.A.R.]]'' loves this trope. There's the Armacham Labs and Origin Facility in the first game, the Perseus Compound in ''Perseus Mandate'', and several others in ''Project Origin''.
* ''Franchise/{{Halo}}'':
** The Forerunners' Flood research labs are the most common type found in the series.
** In the second level of ''VideoGame/Halo5Guardians'', Blue Team investigates a lost ONI research station. As it turns out, the Covenant squatters aren't the ones who killed the original occupants; instead, audio logs reveal that [[spoiler:they accidentally killed themselves when a bioweapon test went horribly wrong]].
* The X-labs in ''[[VideoGame/{{STALKER}} S.T.A.L.K.E.R.]]''. They are far and wide [[NightmareFuel the scariest places in the series]].

* The end levels of the first ''Videogame/CrashBandicoot1996'' game are mostly set in Cortex's labs, as you progress through them towards [[TheDragon Dr. N. Brio]].
* The entirety of ''{{VideoGame/Jumper}}'' takes place in a lab [[AlternateHistory abandoned since World War I]].
* Carpaccio's Lab in ''[[VideoGame/WarioMasterOfDisguise Wario: Master of Disguise]]''. It actually isn't abandoned, but Wario's enemies cut the power to slow him down.
* In ''VideoGame/SonicAdventure2'' and ''VideoGame/ShadowTheHedgehog'', several levels on the Ark have this sort of vibe.
* Burst Man's stage in ''VideoGame/MegaMan7.''
* Split Mushroom's stage in VideoGame/MegaManX4 is described as this.

* ''VideoGame/ThePinballOfTheDead'' has the "Movement" table, which is set in a desolate laboratory filled with rusty implements.

* The Aperture Science labs in ''VideoGame/{{Portal}}'' probably fit this trope.
** At first in Portal 1, this is somewhat misleading, as [=GLaDOS=] is still maintaining the test area (where the player spends the majority of his/her time in) where everything is as white and shiny as an iPod, everything that's supposed to move moves, and it seems to be all good, until the player finally reaches the last chamber where [=GLaDOS=] tries to kill you and you make your way through the unmaintained area, you finally get a sense of how long this place has been abandoned. Even more so in Portal 2 where, [=GLaDOS=] is dead, and the whole place is overrun by plants. But the area underground the more modern labs [[TheCakeIsALie takes the cake.]] By the look of things, it was used in the 1950s and abandoned much later. Not to mention that the announcer in the stasis chambers says that you've been in stasis for nine nine nine nine nine nine nine.... days. Which means you've been asleep for quite a while.

* ''VideoGame/PokemonRedAndBlue'' and their remakes have the Pokemon Mansion, where the experiments to clone Mew to create Mewtwo took place (before it had GoneHorriblyRight), and which is now filled with assorted Fire and Poison-types and the scientists' logs of their experiments.
** ''VideoGame/PokemonColosseum'' has the Shadow Pokemon Lab, which has only recently been cleared out when you arrive.
** The Shadow Pokemon Lab returns in ''VideoGame/PokemonXDGaleOfDarkness'', though it's considerably less abandoned this time around, having been reclaimed by its former owners during the five years since Colosseum.
** ''VideoGame/PokemonBlackAndWhite'' has the nearly-abandoned lab where Genesect was created. It's not a dungeon per se, but you will be able to battle the lone scientist still there for two of Genesect's Drives (the other two are in the other version) if you bring it with you to the lab.
* The [=BioSytems=] lab in ''VideoGame/PhantasyStarII''. Birth Valley in ''VideoGame/PhantasyStarIV'' is hinted to be the same location. In both games it's the birthplace of the cute CatGirl in your party.
* Project Purity in ''VideoGame/{{Fallout 3}}'' when you first come upon it.
** Hell, just about any of the "scientific" Vaults will be like this, as well as various abandoned shelters and named buildings.
** In ''VideoGame/{{Fallout 4}}'', a sealed section of Vault 81 was used for virus experiments on Mole Rats, overseen by the Miss Nanny robot Curie, and they continued breeding in there after it was abandoned. In the quest "Hole in the Wall", a kid named Austin discovers the lab and gets infected, so you have to venture into the lair yourself to obtain the cure from Curie, who then becomes a companion.
* ''VideoGame/{{Mother}}''
** In the fangame midquel ''[[VideoGame/CognitiveDissonance Mother: Cognitive Dissonance]]'', there is one that is used to craft Starmen [[spoiler: who are actually Martians]].
** Pictured above is the chimera lab from ''VideoGame/{{Mother 3}}'', it's only mildly creepy at first...then the [[{{OnehitKO}} ultimate]] chimera gets loose.
* The Ocean Lab in ''VideoGame/DeusEx'', where an act of sabotage has released plenty of genetic experiments and thrown the electronic security systems out of whack. The staff is dead to a man.
* ''VideoGame/MarioAndLuigiSuperstarSaga'' has Woohoo Hooniversity, a half school, half laboratory area which has been attacked by Cackletta and Fawful. Enemies include students mutated into mad doctors and [[DoctorMario viruses]].
* During ''{{VideoGame/Mass Effect 2}}'''s Jack's loyalty mission, you go to one [[spoiler: to blow it up, so she can forget her past]].
* Most of ''VideoGame/ParasiteEve2'' takes place there.
* The ''Geneforge'' series has quite a number of these, as experiments GoneHorriblyWrong or GoneHorriblyRight are major drivers of the plot.
* ''VideoGame/TheSecretWorld'' has a couple of these as dungeons. Both are examples of SovietSuperscience with a magical flavor, and both involve projects that were officially abandoned, but with research in fact continuing until closer to the present day.
* The True Lab from ''VideoGame/{{Undertale}}'', is not technically abandoned ([[spoiler: Alphys still goes there from time to time]]) but is still worn down, dark and dirty and has been left unused for a long time, and is full of [[spoiler: creepy-looking machines, logs about Alphys' experiments with Determination, and the Amalgamates, the terrifying (but [[TheGrotesque largely harmless]]) results of those experiments]].
* The Underground Research Lab underneath Emil's Mansion in ''VideoGame/NieR''

* The first ''VideoGame/TraumaCenter'' game and its remake have the protagonists visit an abandoned Delphi research lab. They comment on how creepy it is, but it was long since picked clean and they're in and out within the space of a cutscene.

* The ''Franchise/ResidentEvil'' series is utterly in ''love'' with this: almost every game has at least one. The Underground Laboratory, first explored in ''VideoGame/ResidentEvil2'', appears in three games and ''possibly'' ''VideoGame/ResidentEvil0'' as well[[note]]It's appearance in that game created a PlotHole as to it's location and, with no concrete proof it's the same facility, fans are divided on whether it is or a similar facility elsewhere[[/note]].

* ''VideoGame/HouseOfTheDead'' uses this in most of the games in the series, notably the 2nd and 3rd games.