The White Star-class gunships in Babylon 5. Thanks to a combination of Minbari and Vorlon technology, these comparatively small ships pack quite a punch and have the maneuverability of a fighter. They're also the only ships of that size that can open their own jump points. They're far from invulnerable, though, and many are lost during the Second Shadow War and the Earth Alliance Civil War. Also, compared to the cumbersome EarthForce ships (no Artificial Gravity or Reactionless Drive) during the Earth-Minbari War, the much larger Minbari ships were this. And let's not forget the Vorlons and the Shadows.
Clark Kent, naturally, on Smallville. This version has no compunctions about dropping into 'Clark time' and using his superspeed to take opponents out.
Eliot Spencer in Leverage. The guy Does Not Like Guns (but is still a pro at using them). His introduction involves a flashback of a retrieval mission in the den of some mob boss with a dozen of the latter's guys armed to the teeth. A few seconds, and tons of gunshots later, we are once again shown the inside of the den with all the guys down and Eliot unharmed. In the same episode, Eliot takes out two professional security guards before a dropped bag hits the ground.
In Game of Thrones, if you are stronger than Brienne of Tarth or Sandor Clegane, they will be faster and more skilled. If you are faster or more skilled (there are almost none who could accurately claim both), they can simply brute force their way past your defenses.
Connor from Angel is this, due to being a Dhampyr. Other Buffyverse characters could be described as this too, but Connor is notable because his fighting style is designed to exploit this as much as possible. (unlike, say, Buffy, who, as a Slayer, is supposed to be this, but draws on her power way more than her speed or her durability)
The Flash (2014) has the Reverse-Flash. He's a lot faster than Flash himself and he's strong enough to toss grown men around like rag dolls.