OTHAR TRYGGVASSEN, Gentleman Adventurer! fits this, especially in the radio play, as lampshadedin this comic (of a radio play). Othar has been "kidnapped" by Ferretina, the Weasel Queen, famous for devouring young men, grilled with cheese. One of the closing questions is "And what kind of cheese goes best with grilled ham?"
Pushed even further into the zone of absolute hamminess by Cheyenne Wright portraying Othar in the audio plays.
Ferretina herself qualifies.
"I think it's the loneliness that makes a...person begin to have...strange thoughts. Thoughts that drive her to explore the twisted, blasphemous back alleys of science. That allows - no - forces her to create monstrosities! Monstrosities fit only to unleash upon those sanctimonious villagers who reviled and mocked her because of her father's experiments!"
Hamminess and chewing the scenery seem to be a consistent side effect of the Spark. Othar and Ferretina are just the ones who do it when they aren't going off on a Mad Scientist rant.
The Jagermonsters have tendencies that way as well.
"Ve kin only redeem ourselfs vit honourable death!"
"Yez, svift, painful, honourable death!"
"Hyu knife, brodder!"
"Right here, brodder!"
"*sigh* Ve didn't gets caught, hyu eediots."
"Whew!"
The as-yet unnamed Doctor Ham who shows up here, escorted by copious lampshading and enough chewed scenery to put the carpenter's kids through college.
Dr. Disaster from Gunnerkrigg Court. He starts hamming it up with his very first lines: "Spacemonauts! The Earth is in peril!" It's unclear whether he's like this all the time, or just acting. Ironically, he has a crush on Jones, the resident Stoic.
Parley knows how important it is to put up a good show (later, Mort joins too).
The Inexplicable Adventures of Bob! has Galatea ("CRAZY? YOU DARE?! ALL THE WORLD IS MAD AND ONLY I AM SANE!!") and Riboflavin ("I SAID BOW, YOU HALF-SENTIENT LEMUR!"). Galatea has a big crush on Riboflavin at one point.
Homestuck's Vriska, a fact which Karkat lampshades in the AlterniaBound flash by effortlessly predicting her next lines without having any Psychic Powers at all. (Initiate a conversation with Vriska as Karkat to see this).
Nathan Fillion puts the "ham" in Captain Hammer. But he's playing a smarmy, self-absorbed superhero caricature—it would be impossible to portray the character any other way. Fillion remarked that it was the only time in his career a director had to tell him to be more of a ham.
Captain Hammer (singing while giving Dr. Horrible the finger): "Everyone's a hero in their WAAAAAAAY?!?"
Doctor Horrible himself becomes Doctor Hamible in the last act, during the song "Slipping", and Act II - Brand New Day is a delicious slice of ham.
O'Malley from Red vs. Blue may very well be the largest ham in the history of Machinima.
"Now be careful, mustn't give away our position with maniacal laughter!"
"Even though what I want is something frightening! WHAT I WANT is something PURE EVIL, AHAHAHAHAHAHAHA!!"
O'Malley's the undisputed king of this in Red vs. Blue, but fellow villain Wyoming is no slouch, and The Director shows shades of this as well at times.
"I don't give a DAMN about you and your committee!"
Strong Bad from Homestar Runner. In SBCG 4 AP, when Dadgeresque, AKA Senor Cardgage, "died", and Dangeresque, AKA Strong Bad, sounded like his head was about to blow off his body. This was just one of his many instances of hamminess, however.
Strong Bad: "Well, I heard a techno song one time that went like, 'Doom doom doom doom', and then this other part came in and it was like, 'Dudalado! Dudalado! Dudalado! Dudalado!' And there's always this high-pitched noise, you know, like a siren that's like, 'DOO-DA-DA-DIDDLE!! DOO-DA-DA-DIDDLE!!!' And then there's the obligatory old movie quote from some sci-fi movie, it's like, 'The system is down! DOO-DA-DA-DIDDLE!!! DOO-DA-DA-DIDDLE!!!!'"
Strong Bad: "WHY? WHY DO MY THIRTY-YEAR-OLD ELECTRONICS KEEP BREAKING ON ME???"
The lonelygirl15 recurring villain Ted McKinley (aka PharmaGuy), especially in his first appearance.
The Angry Video Game Nerd alternates between somewhat constrained and really exaggerated Unstoppable Rage (particularly during rants, and sometimes even silent, like his Kaiju impersonation during the Godzilla video).
Spoony can serve up the ham, especially as Dr. Insano. Angry Joe can be as passionate as his name suggests and Linkara has his moments too, for HE is A MAN!.
Out of the women on the site, The Nostalgia Chick's sidekick Nella is the one who revels in ham delightfully.
Phelous in general, especially when he starts growling his words.
Diamanda Hagan could easily give Nella a run for her money. Ham-off away!
Linkara's dad as Whatley in the Silent Hill: The Grinning Man review, in a wig that wouldn't look out of place in Spinal Tap, and it is glorious.
Mille Chanteau of Ilivais X is the queen of ham. If she's in battle, it's all but guaranteed anything she says is an epic speech of some kind, and it's not limited to then either. Of course, there's also Seyne (that comes with being a Sanger ZonvoltExpy though), most of the GEKICOM and STRUQ members, hell, even Iriana has her moments.
There Will Be Brawl is a series that plays melodrama so straight that it's almost a parody, so this kind of acting is a requirement. Ganondorf and Wario (played by Ham extraordinaire Kyle Hebert) deliver.
Snape, Draco, and Voldemort all qualify, with Snape being the most egregious example by far. Dumbledore is up there as well, especially when he starts lapsing into a Yiddish accent. Really, half of the play is the actors all trying to out-ham each other... which doesn't detract from it at all.
"Malstrom- World-wide sex symbol to women. When a new article appears, his mailbox gets flooded by the ladies demanding passion from him. "A business article on video games? That is so hot!" they squeal. Each Malstrom article also gains him a million dollars from jet-sitting super secret investors. Malstrom is also prone to self-delusions. ("Hey," he says, "if you are going to have delusions, might as well go for the really satisfying ones!")"