The Furbie-esque Nubbins in Sanctuary are a variant of this — they're only dangerous in large groups and when being directly attacked, but their extremely high reproductive rate and lack of predators outside their natural environment make them potentially highly destructive to the ecosystem. Unfortunately, they're a Hive Mind far brighter than they seem, and are more than willing to sacrifice individual lives to escape and spread. Loook what happens to the large, vicious wolf-like abnormal the team sends after the nubbins. Look at the bones, indeed.
In an episode of Honey, I Shrunk the Kids called "Honey, the Bunny Bit It", Nick Szalinski revives the school mascot à la Frankenstein, and chaos ensues as it runs amok.
An America's Funniest Home Videos episode features a rabbit fighting a snake. The rabbit kicks the snake's proverbial ass, forcing the reptile to retreat up a low-hanging tree, despite the rabbit attempting to yank the snake down for more.
Black Adder: Not quite a killer rabbit, but a joke on the trope. In the Black Adder millennial special, the Roman version of Rowan Atkinson character jokes that Hadrian's Wall that he is guarding is as frightening an obstacle as a rabbit with the word "boo" painted on its face.