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* ''Fanfic/ACrownOfStars'': Shinji and Asuka had finally got the help they needed, they were talking to each other and with the assistance of powerful friends they were ready to take down the BigBad... when the dimensional gate through which they were transporting an army got blocked and they were cut off. Asuka got afraid all this was going to Hell ''again'' because their lives had been a long string of hope spots.
** Described by Asuka in chapter 46:
--->“I just know this is going to go to Hell somehow. It always does. Something good happens, and then the world shits all over us again. You and I meet, then spend years missing each other’s signals. We’re beating the Angels easily, coming together as a team, and then your asshole father springs the Dummy Plug system on us. We survive the Third Impact, then get a world of thugs, rapists, and warlords. And now we finally… talk to each other, and then this… I just know something more is going to go wrong here, because this world hates us,” Asuka said wearily into his chest.
* ''FanFic/ADifferentMedius'' has a particularly cruel one. AU!Sam is swapped with her canon self, and among other things, she prevents a load of angst by defending Buwaro from an angel attack instead of Kieri, preventing the latter from angsting about betraying her own kind, and stops Buwaro and Kieri from playing the Archery Game, preventing Kieri from losing her grip when she would've seemingly missed a target. And, she even gets canon!Iratu to do a HeelFaceTurn and join canon!Rhea's party. [[spoiler: Then Moonshade kills Iratu for betraying him, which wouldn't have happened had Sam not been present.]]
* ''Fanfic/AdviceAndTrust'':
** After getting together Shinji and Asuka's lives had gotten better: they were happier and more stable, they had kicked an EldritchAbomination's posterior together, they were helping Rei to get in touch with her humanity and developing a strong bond with their teammate, their best friends were getting together... and then [[spoiler:the Bardiel incident happened. Hikari got trapped inside Unit-03 and they got fired.]]
** The whole fight against Zeruel was a sucession of Hope Spots. Several times Rei was apparently getting the upper hand or gaining an advantage or rising after getting stomped flat... right before getting pummelled by Zeruel again. And then [[spoiler:Shinji and Asuka came along piloting Unit-03, saved Rei and started to beat Zeruel up... and then they ran out of power.]]
* Late into ''[[http://www.fanfiction.net/s/5362357/1/Carnage_Necropolis Carnage Necropolis]]'', Misty discovers that the L-Ject she got has a chance of curing Ash of his infection. When she reaches him, though, he's too far gone to be healed, and the only thing she can do is kill him.
* ''Manga/{{Evangelion 303}}'':
** After several fights and disagreements Asuka and Shinji got together. They were still confused about their feelings and their relationship, and they still had arguments, but they were happy. Then in chapter 7 [[spoiler:the plane Asuka was piloting crashed. She survived but she spent several months in a coma and when she woke up, she was a different, angrier person.]]
** Later Shinji managed to stop her from [[spoiler:committing suicide]], and it looked like if he had finally reached her out and they could start to repair their relationship. The next day she ran away.
* ''Fanfic/ThousandShinji'': When he arrived on Tokyo-3 Sinji was gradually getting what he always wished: a family (Misato, Rei), a girlfriend (Asuka), and friends. He seemed powerful and cunning enough to take down any enemy, and he and his fellow pilots worked together marvelously. Then [[spoiler:Rei started to behave like a jealous {{Yandere}} and broke their teamwork, his best friend got crippled and his girlfriend's best friend got killed. He got stuck inside Unit 01 and after getting retrieved he was in a coma for a month. During that time Asuka, Rei and Misato fell utterly apart. Asuka got mind-raped by Arael and was in a coma since then, Rei hang herself and blew herself up to destroy Armisael and Misato got jailed.]] Needless to say, when Shinji woke up, he was... more than a ''little'' angry.
* ''FanFic/WinterWar''. After many of the cast have already been killed or suffered even [[TorturedMonster worse]] [[FateWorseThanDeath fates]], Grimmjow, Hanatarou, and Hisagi [[spoiler: or rather, Kazeshini controlling his body]] discover [[spoiler: the original Kurotsuchi Nemu]] alive in Mayuri's lab. She's in bad shape, but they hope Orihime can heal her. She explains otherwise: [[spoiler: her zanpakutou has been severed and her soul is being drained into her clones... which would remain even if Orihime tried to reject the damage.]] She [[ICannotSelfTerminate asks them to kill her]], and after some hesitation, they do.
* In the ''WesternAnimation/MyLittlePonyFriendshipIsMagic'' fan fic ''Discorded Ponies'' (the first part of the ''FanFic/PonyPOVSeries''), the AlternateUniverse BadFuture [[http://alexwarlorn.deviantart.com/art/Discord-Ponies-Epilogue-259589869 epilogue]] has Twilight Tragedy turn back into Twilight Sparkle after Traitor Dash couldn't bring herself to kill her best friend. Twilight was then about to embark on fixing everything, but then Discord appears and turns her into Twilight Tragedy again. Turns out she only becomes herself again when and if he feels like it...
** There's another one near the end of the Generational Transitions arc: [[spoiler: Star Catcher uses the Rainbow of Light to defeat Strife, and Pinkie saves Minty from being deleted from existence... only for Minty to die of blood loss anyway, and Strife to reveal that she's [[IAmNotLeftHanded even more powerful than she let on]]]].
** [[spoiler: The [[BadFuture Dark World!]]Mane Six are StormingTheCastle. They've beaten and [[HeelFaceTurn redeemed]] Traitor Dash, killed [[BigBadWannabe the Valeyard]] (causing him to regenerate back into the Doctor), torn apart Discord's defensive line, and manage to convince [[GeniusLoci the Castle]] to remain neutral in the coming conflict. Just when it seems everything is going their way and it looks like they'll save everyone, it's revealed Fluttershy's essentially dead (though in Pony Heaven) and Fluttercruel is merely using her body. Then during the showdown with Discord's remaining minions, it looks like the heroes have the upperhand, Rarity killing Fluttercruel and Spike gaining the upperhand on Rancor... then Angry Pie rips Twilight's Element out and leaves her to die of RapidAging.]]
*** This leads to another one when [[spoiler: Twilight arrives, having survived by obtaining Trixie's Element of Magic, [[BigDamnHeroes just in time to save Applejack and Apple Pie from Angry Pie]]. Her friends all cheer at the fact she's survived... but Twilight doesn't pay them heed and instead begins giving Angry Pie a NoHoldsBarredBeatdown and a viscous TheReasonYouSuckSpeech. And then, [[OhCrap familiar black tendrils begin wrapping around her]] as she begins to [[SuperpoweredEvilSide turn into a vengeance crazed Nightmare.]]]]
** Happens in "Crushed Pearl Necklace", [[spoiler: when after [[OneWingedAngel Odyne!]]Cruelty is defeated, it seems Pinkie Pie has survived the battle...only for Rainbow Dash [[DeadAllAlong to pass right through her when she goes to hug her]].]]
* ''FanFic/InnerDemons'' has several:
** Rarity, Apple Bloom, and Spike are escaping from the castle and planning to go to Shining Armor and Cadence for help in the hope that the latter can use her powers to return Twilight to normal after being possessed by her [[EnemyWithin Queen persona]]. [[spoiler: [[TheDragon Trixie]] intercepts them, and while Apple Bloom and Spike escape, Rarity is recaptured. Meanwhile, Queen!Twilight has learned of their plans; by the time the heroes are reunited, she's gotten to Cadence and [[BroughtDownToNormal stripped her of her powers]].]]
** After [[spoiler: [[TheStarscream Scootaloo]]]] goads Rainbow Dash into a race for the title of fastest pegasus, Dash pulls off a Sonic Rainboom and it appears she's going to win. [[spoiler: Then Scootaloo pulls off a firey equivalent of the Rainboom and not only wins but drives Dash into the ground.]]
** Applejack and Rarity are fighting their way through Queen!Twilight's forces, and it looks like they're going to win and escape, only to be confronted by [[spoiler: the brainwashed Princess Luna]].
** Spike confronts Queen!Twilight in Fillydelphia, and for a moment his [[IKnowYoureInThereSomewhereFight heartfelt pleas]] seem to be getting through to the real Twilight -- then she punches him across the room.
** Applejack finally confronts Queen!Twilight and overpowers her; it appears as though she's going to kill her and, at worst, give the story a BittersweetEnding. [[spoiler: Unfortunately, she can't bring herself to kill her best friend, giving Queen!Twilight the opportunity to beat her, and place her under a spell that leaves her [[FateWorseThanDeath in a state of perpetual fear]]]].
** During the FinalBattle, [[spoiler: the Elements of Harmony are used on Queen!Twilight and, combined with her inner light and own Element of Magic, force the darkness out of her, both freeing Twilight and evolving her element to armor... but then the darkness takes on a [[EnemyWithout life of its own]], which proceeds to kidnap Twilight and flee.]]
* ''FanFic/AceCombatTheEquestrianWar'' has a few:
** In chapter 14, the pegasi manage to [[spoiler: retake Cloudsdale]]. Then [[spoiler: Canterlot is attacked and besieged by the griffins]].
** In chapter 17, [[spoiler: Canterlot is liberated and the griffins are driven out of Equestria]]. But by the end of the chapter Derpy reveals that [[spoiler: Axe told her about Red Cyclone's new superweapon, Fortress Intimidation]].
** In chapter 19, [[spoiler: Fortress Intimidation is destroyed, Red Cyclone dies]] and it seems the war is over. But as ponies and griffins alike celebrate, [[spoiler: Firefly is struck down]].
* The first time Calvin reels in the canoe in ''Fanfic/CalvinAndHobbesTheSeries'', it appears to be going good until it gets stuck on a rock. [[spoiler:It gets subverted when Calvin uses a ChekhovsGun to get it back to shore.]]
* ''FanFic/MyLittleMagesTheNightmaresReturn'': [[spoiler: When Nightmare Moon first emerges, Celestia very nearly manages to purify her. But since that would render the entire plot null and void, the [[TheDragon Grand Master]] interferes and mortally wounds her.]]
** [[spoiler: After Nightmare Moon announces herself and that Celestia is dead, Twilight receives a letter via Spike, which implies she's still alive. However, it turns out the letter was [[DeadManWriting only supposed to be sent if Celestia died]], which kills the mood.]]
* ''[[http://hetalia-kink.livejournal.com/15769.html?thread=41731481#t41731481 Close Every Door]]'' has two. The first is when [[Webcomic/AxisPowersHetalia Russia]] realizes that [[spoiler:America is insane and most likely is the one who kidnapped England. It's ruined when [[CassandraTruth no one listens to him]], thinking that he is just slandering America out of jealousy.]] The second is when [[spoiler:a witness tells Canada that a man matching England's description was seen carried into a house in Virginia, leading the nations searching for him to scour the state. Unfortunately America realizes that they caught on, and moves England to another state.]]
* In the ''Fanfic/ChildrenOfTime'' finale, Beth finally makes it into the heart of Moriarty's base to rescue [[Literature/SherlockHolmes Holmes]]. For a moment, he even seems pleased to see her. But just for a moment... because then he tells her ThatManIsDead. The scene rolls BrokenPedestal, BreakTheCutie, HeroicSacrifice, DrivenToSuicide, and FamilyUnfriendlyDeath all in one go.
* ''[[FanFic/FriendshipIsMagicTheAdventuresOfSpike Friendship Is Magic: The Adventures of Spike]]'': The Equestrian military manages to start winning against the changelings, and the Mane Six reach the Elements of Harmony. [[spoiler: Then changeling reinforcements show up, and the Elements of Harmony refuse to activate. (It's implied to be due to the others not trusting Twilight earlier.)]]
* The [[Fanfic/PonyPOVSeriesChaosVerse Chaos Verse]] has a couple during the FinalBattle. First, [[spoiler: Discord and Fluttercruel seemingly defeat [[BigBad Nightmare Phobia]], only for her to absorb the Shadows of Oblivion and go OneWingedAngel]]. Shortly after that, [[spoiler: they and the Princesses destroy her second OWA form, only for it to turn out to be a puppet of her ''true'' form.]]
* From [[http://www.fanfiction.net/s/9217083/1/Dwarfed-or-The-Blessed-Disaster The Blessed Disaster]] : "I had had my fill of life. Then one day a child came to our lives and made me see the wonder that was still in the world... She's dead now."
* ''FanFic/TwilightRevised'' has one near the end when Twilight breaks free of Nightmare Moon's control and shoots her right through the chest with a magic laser. [[spoiler:and then Nightmare Moon wins anyway.]]
* Discussed in ''[[Fanfic/AradsStardust Stardust]]'' chapter 20: [[spoiler:Shen reprimands Lana for making Twilight think that Matt's romantically interested in her, saying that this kind of false hope will only make things worse once the truth comes out. Lana insists in retort that false hope is better than no hope.]]
* ''FanFic/MegaManDefenderOfTheHumanRace'' has this. In episode 11, chapter 7, everyone is geared up for a fight against Project G-2. There were heartwarming scenes before the battle, everyone is confident Mega will do his best, and he has the full support of the Robo-Commandos and the US army. [[spoiler:And then ''everyone but Mega Man is killed'']].
* ''FanFic/RosarioVampireBrightestDarkness Act VI'' has a brief moment of this during chapter 42. In an attempt to bond with Arial and win her approval, Mizore asks her how Dark was when she first met him. Arial softens toward her for a few brief moments to tell her the story... and then goes right back to her "Mizore isn't worthy of Dark" mentality as soon as she's done, much to Mizore's irritation.
* Occurs twice in ''[[FanFic/TheVinylAndOctaviaSeries Vinyl and Octavia Duel Destiny]]'':
** The first time, Octavia is given evidence which proves who the real murderer is. She's ready to use it...[[spoiler: only to be disbarred from practicing law since it's inadmissible evidence.]]
** The second time, the courtroom doors burst open and it seems that somepony is about to come through and save the case...[[spoiler: only for it to be revealed that Vinyl opened the door with her telekinesis in the hopes of invoking this.]]
* Chapter 5 of ''FanFic/DespairsLastResort'' has a series of them. After going through four trials and witnessing the execution of [[spoiler: Arata]], the seven remaining students declare that they'll no longer play by Monokuma's rules and refuse to kill. The next day, he shows up with a new motive and reveals [[spoiler: not only is there a thief who's identity is unknown but someone among them didn't lose their memories and is working for him]]. It seems like they're still going to work together and decide to look over all the strange items that have been appearing in their rooms. But then Takara and a few others realize [[spoiler: even though they met in a location without cameras, the mole was still with them and could tell Monokuma everything.]]. The students start fighting with each other for a number of reasons, though after Miyako tells them they're being foolish it seems like everyone's going to settle their differences. Miyako even has a plan to make sure it all stops. [[spoiler: Turns out that plan of hers involves committing suicide so the others can work together and letting the killing end.]]
* It was sort of a [[FreezeFrameBonus Blink And You'll Miss It]] but at the end of Crippled - Body and Souls, by Kevin D. Hammel when Shampoo knocked Ranma out of the wheelchair he landed on his legs and felt pain. It was forgotten in an instant due to the situation but it could be a sign that Ranma is regaining feeling in his legs.
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