This may sound kind of weird but I think it's nice that this version of Dr. Frankenstein wasn't an evil man and had taken it upon himself to try protect his creation from Dracula, treating him sort of like a son. Makes his ultimate fate all the sadder though...
Dr. Frankenstein: I could never allow him to be used for such evil.
Dracula: I could. In fact, my brides are insisting on it.
Frankenstein's creature's look when Anna thanks him, after he saved her from one of the brides. For someone who has only been treated like a monster or a tool in his life, that thanks meant everything to him, even making him more determined to help the heroes against Dracula.