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Even more so, when they save Otto from the monkeys.
Buck giving the poncho he's sewn in the Alamo prison with the caption "Larry 3K" to Larry ( Before Buck backed away from Larry trying to hug him) in "Forget the Alamo."
Otto's birthday party in "Love At First Flight". The whole thing is unbelievably sweet, especially when Otto hugs Tuddrussel and Larry after opening his presents.
Otto reuniting with Larry and Tuddrussel at the end of "Orphan Substitute," after Otto is forced back into the orphanage and Larry and Tuddrussel are struggling to find a replacement boy genius to help them on their missions.
While even the following dialogue to be sort of sad and bittersweet, Otto begging for forgiveness during the scene is just precious. You just want to give this kid a hug?
Otto: I'm sorry I got mad at you I'll be good and I'll let you win at video games and I'll let you steal my dessert and I don't want anyone throwing me in trash cans anymore except you!
Tuddrussel: Aww, I'd throw you into a trash can any day, little buddy!
Lewis and Clark getting back together in "Lewis and Clark and Larry."
Clark: I've been doing terrible without you! My clothes stink, I don't know where I am, and I'm starving! I neeeed you!
Lewis:(delighted gasp) You don't know how long I've been waiting for you to say that.
The scene in Hate And Let Hate where Otto makes wooden copies of Larry and Tudrussel and calls them all "one big happy family" (with Otto mimicking Tuddrussell and Larry before stuffing his face with sand and salt water). It really shows that he does see Larry and Tuddrussell as his parents and the only people in the universe who care about him (even though they didn't realize he was gone until near the end).
"Father Figure of Our Country" has a pretty big one; Tuddrussel gets incredibly jealous of George Washington as the president spends the day with Otto. He treats Otto with more fatherly affection than Tuddrussel could ever muster up, teaching him the things that Tuddrussel had failed at doing and paying attention to his needs. Then towards the end Washington askes Otto if he could adopt him! Otto's overjoyed reaction is just sweet in itself. And when Tuddrussel comes out to challange Washington over who Otto belongs to, Otto has this to say-
Otto: "Wait, you don't understand! I want to stay. (BEAT) But I can't. My place is with Time Squad." Then we get this-
Tuddrussel: Wait, so you're pickin' me over him then?
Otto: "No one could ever replace you, Tuddrussel."
In a Real Life example, on May 4, 2012 Rob Paulsen 's podcast "Talkin' Toons" Mark Hamill was the guest of the week. In the interview the very first topic Mark talks about is Time Squad, saying that he had so much fun working on it and how he loved working with Rob and Pamela Adlon and Dave Wasson. He defended it from the snarky comments that called it a "Peabody and Sherman" ripoff, and just spoke so lovingly about it. He had also expressed wishes that it had gained a cult following like the current Cartoon Network show, Regular Show. Then, Rob and Mark just burst out talking in their respective voice roles as Tuddrussel and Larry, which is just hysterical. Their discussion on Time Squad kept coming back within the interview and they both seemed nostalgic and respectful of the show. Realizing just how much the show was ahead of its time, and knowing that these two voice actors who have done so much work within the last 20 to 30 years have such loving memories about it, is so wonderful to know as a fan.