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In the final scene of the third O'Neill issue, Vic visits Myra's daughter at the orphanage (It Makes Sense in Context). He helps some kids build a snowman. And he waxes nostalgic about how kids don't have the cares adults do.
Almost every conversation Renee and Vic have reveals some sort of deep emotion, but the Crowning Moment is split between the last two conversations they have: Before Vic lapses into his cancer-induced delirium, and before he finally dies just beyond the gates of Nanda Parbat. They are awful, but they reflect the strength of the bonds between them and just what they mean to each other.