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When Cloud goes missing, and later captured by Hojo all the prominent characters do their best to find him.
In the end, it's Cloud's act of kindness in curing Genesis that ultimately results in preventing a whole lot of future misery, rather than bloody vengeance on a Sephiroth who hasn't become a bad guy yet.
In one of the spin offs, Vincent takes Sephiroth to meet Lucretia.
From the same spin off, Cloud finally acknowledging Sephiroth as his friend.
When Cloud finally gives the dying Angeal the spring water.