Near the end of the game, if you saved him from the hotel ambush at the end of the first act, your brother Paul appears on a holocomm to say hello. He advises you on the three possible ways you can resolve the situation, but doesn't recommend one above the other - he just says that he believes in you, and that you should do what you think is right.
JC Denton: You sound good. I guess you have the killswitch beat.
Paul Denton: I'm much better. Yes. I'm going to make it - and you will, too. Just do what you think is right.
Several times in the story you visit 'Ton Hotel, run by Gilbert Renton, an old friend of the Denton brothers and a father struggling to protect his rebellious, estranged daughter. The girl ultimately brings in Jojo, a street thug who treats the whole place (not to mention her) as his own. Unsurprisingly Gilbert asks you for a gun to protect her. If you can do it in such a way that he kills Jojo, without obvious help (for a certain value of obvious - you're good as long as Gilbert lands the final blow), and both Rentons survive, he finally earns the respect of his daughter.
You might encounter a beggar near the hotel in Hong Kong asking for 20 credits. You ask her what she want to do with the money and she'll admit it's for drugs. You have the option to give her money, stating that "a forgotten virtue like honesty is worth at least 20 credits."