Setting the tone for years to come, David Walliams and Rob Brydon's absolute elation when they become the first ever team to nail the "Say What You See" question in the 2004 edition.
One year of BFQ had the guest star as Lola the cat, who was infamously thrown into a bin. When they played the clip, Jimmy Carr asked her owner to "shield Lola's eyes", and the comedians all reacted with shock at the clip, with Alan Carr saying in horror, "Why would you do that?"
On the 2012 90's quiz, Jack Whitehall's unabashed look of joy when he realizes that the secret identity of the mystery guests were as two of the Teletubbies.
What he says next is less heartwarming
Jack: I always wondered what you guys would look like when I opened you up...
Jimmy: You couldn't sound more like a creepy serial killer if you tried.
Jack: You won't know this, but I was the baby that was the sun.
During the 2009 edition of the show, Rob Brydon and Claudia Winkleman are set up as teammates, and decide to pretend that they're a newlywed couple. Later, after originally appearing reluctant to do his "Small Man in Trapped in a Box" routine, Rob immediately relents to it after Claudia (literally) prods him in a gentle fashion. Afterward, Claudia is pretty much beaming with pride.
Claudia: That's who I married.
During the Quiz of the Noughties (00's), Jimmy Carr gently jokes around with the Davies-Carr children (of "Charlie bit my finger" internet fame).
When Richard and Greg get an answer wrong in BFQ 2015, all of the other panelists jump to their defense.
In a minor way: At the end of 2013's Quiz of the 90s, a gunge tank is brought out for the losers to pay their forfeit. However, Jonathan Ross immediately jumps to the losing team's defence. He argues that because no one informed them of the gunge tank beforehand the losers didn't deserve to pay the forfeit, and that Jimmy should instead. He manages to get the losers off the hook this way.