Wee, Ill start. In the movie: Who was making the noise for help before the mayor's stapler incident? How did it reach Horton's ears before there was a special way for the sound to travel?
Maybe it was all the people freaking out all at once when it suddenly made that big swerve, or just Jojo testing his array in the observatory. Or maybe the world itself cried out. I dunno.
Maybe the "yelp" Horton heard was the Mayor calling for his assistant, Miss Yelp.
Personally, I have a theory, regarding... KATIE. Whatever she really is, she knew what the speck was from the beginning. After rewatching, she's the only other person in that scene with an 'Oh Crap' look when the speck first floats by. Everyone else is just bewildered at Horton's antics. But she looked like she knew exactly what was going on there. Especially with the last shot being her floating out of the Jungle of Nool and into the Void between all worlds, which are all revealed to look like specks of dust.
Dr. Larue, the doctor Mayor McDodd went to in order to find out what would happen to his floating speck of a world, starts to believe him later in the movie because of the unexplainable snow... yet does NOTHING when he's being ridiculed by the Council! She told him straight to his face that he was right about their world being in terrible danger, so why doesn't she step up and defend the poor man?
Maybe she was afraid of being ridiculed too?
Vladd drops the flower into an endless field of flowers that all look identical. So why did Horton go through what was obviously an unrealistic task of finding that one flower with that one dust speck. No one else would have bothered. The speck was safer in that sea of flowers than standing alone on an easy vantage point on a cliff.
Horton was feeling protective of his tiny friends. He may have feared that Katie would later go find it and cause more harm.
How exactly did Morton learn that Sour Kangaroo sent Vlad Vladikoff after Horton? (In the movie)
All versions of the story portray many of the denizens of the Jungle of Nool as loose-lipped yentas. It can be assumed that Morton heard it from a guy who knows a guy who knows a guy, etc.
In the climax, how did Kangaroo and the residents of Nool get to Horton despite the fact that he destroyed a bridge earlier, and the only way to get to Mount Nool was across said Bridge?