If James is Gregory's grandson, then surely Gregory has a son or daughter, right? Where are they? Did they go sane and leave? Did they die? Is James actually his son, not grandson? Was he just magicked out of nowhere?
This isn't the only instance of seeing a guy with his grandkid without seeing the generation in-between in fiction. Although with this show, the lack of explanation fits the mood perfectly.
Kind of weird a question, but does anybody else find it weird the that the hotel is called (the) "Gregory House"?