- Webanimation.Happy Tree Friends: The main cast consists of anthropomorphic animals who live in a world where they interact with real animals. For example, in an episode involving a trip in the woods, Lumpy the moose gets mauled by a grizzly bear (about four bears make up the cast! So what does that make the grizzly bear?). Again, in a short Christmas short, Petunia gets stomped to death by a deer, which looks more like a real world deer compared to Mime the deer.
- Many of the cast members are also shown keeping pets, such as cats, gerbils, dogs, and an elephant on one occasion.
- In the episode "Junk in the Trunk", one of the animals kidnapped by Lifty and Shifty is a monkey. The spin off series Ka-Pow! has a monkey named "Buddhist Monkey" as one of the the main protagonists, and said character also sometimes pops up on movie screens in the main series.
- During one episode the characters make a trip to the zoo, encountering animals such as rhinos, snakes and ducks.
- "Home is where the Hurt is" has a moose head in a house. Given that Lumpy was one of the workers in the house, it makes you wonder...
- Averted in Tasakeru, where intelligent animals are "sentients" and unintelligent ones (all non-mammals, boars, rats, goats) are "animals".
- Darwin's Soldiers had this occur twice in the 3rd RP.
- Cpl. Stern has this to say:
Cpl. Stern: So, Vipers. I understand that you can sense motion and heat differently than humans can. Does it works like a real snake's senses?
- Birds chirping outside the window wake up Shakila. Pretty damn sure that said birds are non-anthro.
- Cpl. Stern has this to say:
- One Protectors of the Plot Continuum interlude has this when human agents Laburnum and Foxglove go to the Real World for a holiday and bump into agents Naomi (human), Drake (anthro fox in human disguise), Stormsong (anthro weasel in human disguise), Skyfire (anthro stoat in human disguise), and Stormy and Sky's adopted kids Molly (anthro ferret in human disguise) and Moses (anthro otter in human disguise). In a conversation, Drake wants to go to a zoo, but Sky argues against it on the basis that Molly would have a fit (she broke down after encountering a pet shop).
- The Annoying Orange once talked to a sentient iPhone, but has been shown to have a smaller, non-sentient iPhone of his own in later episodes.
- On Gaia Online, there are normal animals such as the companion items and the fish in people's aquariums, talking animals who may or may not wear clothes such as the tailcoat-and-hat-wearing cat NPC Rufus, furry avatars created by modifying the human base with animal-related bits such as ears, tails, paws and fur, and the animal bases (which are shorter than humans, but still walk upright). It's rather interesting seeing four different levels of anthropomorphism on the same website, or on occasion in the same page of a forum thread.
Rufus the Cat: I don't get along so well with other cats. They never have much to say...