In Ys I & II Chronicles, shooting the villagers in the second game with the Fire spell results in downright hilarious quotes. Of course, they might also get kinda pissed about it.
From the English version of Ys: The Oath in Felghana, we have this Dogi the Wall-Crusher quotenote Probably not a coincidence that this quote was put on Dogi's profile on XSEED Games's English site for the game.:
"Oh, Mams! Why you gotta bust my walls like that?"
From Ys: Origin, when Yunica receives the help of the goddess Feena in order to cure her friends from a petrification spell, she says exactly this before leaving the room:
Yunica: Thank you lady Feena! I love you!
The fact that the screen shakes while she says this and the reaction of Feena and the others make this scene funnier.
Memories of Celceta has one when Karna climbs to the highest point in the starting town in order to try and find Adol amongst the crowd. The citizens are afraid she's set up for a suicide jump and try to talk her down, but she can't hear her and simply waves to all of them. They then send General Leo to scale the wall and bring her down. As he begins climbing, she spots Adol, jumps down from her position, and delivers The Glomp after landing, of course not understanding that her actions aren't entirely normal outside of her village.